Knopp Neurosciences Inc.

Willow Street, PA, United States

Knopp Neurosciences Inc.

Willow Street, PA, United States
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Patent
Knopp Neurosciences Inc. | Date: 2013-08-22

Methods for preparing chirally purified substituted 4,5,6,7-tetrahydro-benzothiazole diamines such as, for example, (6R)2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole and purifying a dominant enantiomer of substituted 4,5,6,7-tetrahydro-benzothiazole diamines from entantiomerically enriched mixtures of substituted 4,5,6,7-tetrahydro-benzothiazole diamines are provided herein.


Patent
Knopp Neurosciences Inc. | Date: 2013-07-15

Pharmaceutical compositions of (R)-pramipexole and methods and kits of using such compositions for the treatment of neurodegenerative diseases, or those related to mitochondrial dysfunction or increased oxidative stress are disclosed.


Patent
Knopp Neurosciences Inc. | Date: 2013-04-12

Compositions of predetermined amounts of R(+) pramipexole and S() pramipexole and methods of using the same, including for the treatment and prevention of Parkinsons disease, are provided.


Patent
Knopp Neurosciences Inc. | Date: 2012-10-10

Pharmaceutical compositions of (R)-pramipexole and methods and kits of using such compositions for the treatment of neurodegenerative diseases, or those related to mitochondrial dysfunction or increased oxidative stress are disclosed.


Therapeutically effective amounts of R(+) pramipexole and S(-) pramipexole for use in the treatment of Parkinsons disease or the symptoms thereof are provided.


Patent
Knopp Neurosciences Inc. | Date: 2012-12-20

Pharmaceutical compositions of dexpramipexole and methods of using such compositions for the treatment of ALS are disclosed.


Pharmaceutical compositions comprising therapeutically effective amounts of R(+) and S(-) pramipexole, multicomponent pharmaceutical compositions of the same, and therapeutically effective amounts of R (+) and S(-) pramipexole for use in the treatment or prevention of Parkinsons disease or the symptoms thereof are provided.


Patent
Knopp Neurosciences Inc. | Date: 2012-09-12

Pharmaceutical compositions of (R)-pramipexole and methods and kits of using such compositions for the treatment of neurodegenerative diseases, or those related to mitochondrial dysfunction or increased oxidative stress are disclosed.


Patent
Knopp Neurosciences Inc. | Date: 2012-05-09

Pharmaceutical compositions of R(+) pramipexole and methods of using such compositions for the treatment or prevention of diseases associated with or related to mitochondrial dysfunction or increased oxidative stress are disclosed.


Modified release pharmaceutical compositions (controlled release, sustained release, and/or extended release) of the R-(+) enantiomer of pramipexole (RPPX) and methods of using such compositions for the treatment of neurodegenerative diseases, or those related to mitochondrial dysfunction or increased oxidative stress are disclosed.

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