KNC Daishin Laboratories Co.

Chengxiang, China

KNC Daishin Laboratories Co.

Chengxiang, China
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PubMed | Baoding University, Hebei University, Shanxi University and KNC Daishin Laboratories Co.
Type: | Journal: Biosensors & bioelectronics | Year: 2016

Two new acetylenic compounds were designed and synthesized as the probes to realize the detection and recognition of Au(3+). The latent fluorophores was rearranged into the fluorescent coumarin derivatives with strong fluorescence by a gold ion-mediated hydroarylation reaction. In the meanwhile, the generated fluorescent substances were also isolated and characterized. The probes identified Au(3+) ions highly selectively over other biologically relevant metal ions, and detection concentration of Au(3+) was as low as 0.1M or less. Fluorescent imaging of Au(3+) in living cells was also successfully demonstrated.


Yang Y.,Hebei University | Yang Y.,KNC Daishin Laboratories Co. | Bai B.,Hebei University | Jin M.,Hebei University | And 6 more authors.
Biosensors and Bioelectronics | Year: 2016

Two new acetylenic compounds were designed and synthesized as the probes to realize the detection and recognition of Au3+. The latent fluorophores was rearranged into the fluorescent coumarin derivatives with strong fluorescence by a gold ion-mediated hydroarylation reaction. In the meanwhile, the generated fluorescent substances were also isolated and characterized. The probes identified Au3+ ions highly selectively over other biologically relevant metal ions, and detection concentration of Au3+ was as low as 0.1 µM or less. Fluorescent imaging of Au3+ in living cells was also successfully demonstrated. © 2016 Elsevier B.V.

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