KMC Manipal

Karnataka, India

KMC Manipal

Karnataka, India
SEARCH FILTERS
Time filter
Source Type

Jayaram A.A.,KMC Manipal | Rao M.S.,KMC Manipal | Padmakumar R.,KMC Manipal | Abdul Razak U.K.,KMC Manipal
Journal of Clinical and Diagnostic Research | Year: 2017

Coronary artery spasm is an intense vasoconstriction of the coronary arteries and may be responsible for the myocardial ischemia, myocardial infarction as well as sudden deaths. Coronary angiography is generally needed to identify the cause. Coronary artery spasm is a multifactorial disease with underlying mechanism still poorly understood. Here, we present case of a 48-year-old male with no significant past history who presented with acute episodic onset chest pain. Clinical, Electrocardiography (ECG) and echocardiographic findings suggested pericarditis but a diagnostic coronary angiography revealed significant coronary vasospasm. Patient’s symptoms significantly improved with calcium channel blockers and Nitroglycerine (NTG). © 2017, Journal of Clinical and Diagnostic Research. All rights reserved.


Sachidananda A.,KMC Manipal | Lin J.T.G.,MMMC Manipal | Usha A.,KMC Manipal
Journal of Global Pharma Technology | Year: 2010

Diabetes mellitus is a growing epidemic and the cost of treating diabetes is increasing alarmingly. There are only few published studies on the cost incurred annually by diabetes patients of India. In this context the present study focuses on the annual medicine and consultation cost spent by the diabetic patients with or without complication. In this retrospective study we have analysed the data of 239 patients who were utilizing the medical care in a teaching hospital. The annual cost spent on consultation, medicine and treatment of different complication in terms of laboratory services, medicine and surgery (if any) were analysed. The data was analysed by Graphpad statistical software The annual medicine cost spent was 10584.71±2113.55 (in INR), 19326.91 ±3253.05 and 25960.2±5698.9 respectively in uncomplicated (group 1), complicated nonhospitalized (group II) and complicated hospitalized patients (group III) respectively with statistically significant difference between group I and II (p=0.02) and I and III (p=0.004). The annual consultation charges spent in these groups were 218.48±12.09, 395.40±31.70 and 742.5±102.44 in group I, II and III respectively. There was a significant difference in annual consultation charges spent between patients who had neuropathy, ischemic heart disease, cellulitis, foot ulcer (p<0.0001). The annual medicine and consultation cost were significantly high in patients who are having one or the other complication and patients with longer duration of illness. © 2009, JGPT.


Ibrahim S.,Louisiana Tech University | Chowriappa P.,Louisiana Tech University | Dua S.,Louisiana Tech University | Acharya U.R.,Ngee Ann Polytechnic | And 3 more authors.
Medical and Biological Engineering and Computing | Year: 2015

Prolonged diabetes retinopathy leads to diabetes maculopathy, which causes gradual and irreversible loss of vision. It is important for physicians to have a decision system that detects the early symptoms of the disease. This can be achieved by building a classification model using machine learning algorithms. Fuzzy logic classifiers group data elements with a degree of membership in multiple classes by defining membership functions for each attribute. Various methods have been proposed to determine the partitioning of membership functions in a fuzzy logic inference system. A clustering method partitions the membership functions by grouping data that have high similarity into clusters, while an equalized universe method partitions data into predefined equal clusters. The distribution of each attribute determines its partitioning as fine or coarse. A simple grid partitioning partitions each attribute equally and is therefore not effective in handling varying distribution amongst the attributes. A data-adaptive method uses a data frequency-driven approach to partition each attribute based on the distribution of data in that attribute. A data-adaptive neuro-fuzzy inference system creates corresponding rules for both finely distributed and coarsely distributed attributes. This method produced more useful rules and a more effective classification system. We obtained an overall accuracy of 98.55 %. © 2015, International Federation for Medical and Biological Engineering.


PubMed | KMC Manipal, MIT Manipal, Louisiana Tech University and Ngee Ann Polytechnic
Type: Journal Article | Journal: Medical & biological engineering & computing | Year: 2015

Prolonged diabetes retinopathy leads to diabetes maculopathy, which causes gradual and irreversible loss of vision. It is important for physicians to have a decision system that detects the early symptoms of the disease. This can be achieved by building a classification model using machine learning algorithms. Fuzzy logic classifiers group data elements with a degree of membership in multiple classes by defining membership functions for each attribute. Various methods have been proposed to determine the partitioning of membership functions in a fuzzy logic inference system. A clustering method partitions the membership functions by grouping data that have high similarity into clusters, while an equalized universe method partitions data into predefined equal clusters. The distribution of each attribute determines its partitioning as fine or coarse. A simple grid partitioning partitions each attribute equally and is therefore not effective in handling varying distribution amongst the attributes. A data-adaptive method uses a data frequency-driven approach to partition each attribute based on the distribution of data in that attribute. A data-adaptive neuro-fuzzy inference system creates corresponding rules for both finely distributed and coarsely distributed attributes. This method produced more useful rules and a more effective classification system. We obtained an overall accuracy of 98.55%.


George B.M.,Manipal University India | Kumar A.,K S Hegde Medical Academy | Rao M.S.,KMC Manipal | Rao M.S.,Kuwait University
Journal of Clinical and Diagnostic Research | Year: 2013

Introduction: Few studies regarding foot changes and health of professional coconut tree climbers of south India are report-ed. Medical emergencies are very common, especially due to accidental fall from coconut trees, while on job. Objective of the present study is to analyze the altered biomechanics of lower limb joints used by the coconut tree climbers. Method: Videographs of tree climbing each from a total of 30 male volunteers, all between 30-55 years, engaged in coconut tree climbing profession were collected. Results: The data revealed the coconut tree climbers are us-ing abnormal rages of foot and lower limb joint motions. Conclusion: This study establishes an occupationally induced form of altered biomechanics, which leads to professional health hazards.


Kulkarni C.,KMC Manipal | Vivekanand U.,ASRAM Medical CollegeAndhra Pradesh
Journal of Clinical and Diagnostic Research | Year: 2014

Purpose: To determine the outcomes of extra large temporal sclero-corneal tunnel incision Cataract Surgery.Materials and Methods: This consecutive case series of eyes undergoing temporal tunnel cataract extraction with tunnel length of 8 to 10 mm was identified retrospectively. Surgical procedure details, follow up, complications, visual and astigmatic outcomes at 6wks were recorded and analysed.Results: Ninety six eyes with extra large tunnel incision were identified for analysis from a dataset of 670 manual small incision cataract surgery cases. 58% eyes had NO5 or denser cataracts. Intraoperative complications included, tunnel related problems (1 eye, 1.04%), bleeding into Anterior Chamber (10 eyes, 10.4%), Posterior Capsular Rent (2 eyes, 2.1%). Early postoperative complications included striate keratopathy (7 eyes, 7.3%). The mean Best Corrected Visual Acuity was 6/7.5 (0.1 logMAR) and 98% cases had Best Corrected Visual Acuity of 6/12 (0.3 logMAR) or better at 6wk. The aggregate Surgically Induced Astigmatism was 0.32D at 850.Conclusion: Extra Large Tunnel of length 8 to 10 mm can be self sealing with low SIA. The complication rates and visual outcomes of ETCE are comparable to those of conventional MSICS. This method can be valuable in complicated cases and during learning period. © 2014, Journal of Clinical and Diagnostic Research. All rights reserved.


Thanusubramanian H.,Manipal University India | Patil N.,Manipal University India | Shenoy S.,Manipal University India | Bairy K.L.,Manipal University India | Sharma Y.,KMC Manipal
Journal of Clinical and Diagnostic Research | Year: 2014

The author reports a 55-year-old female diagnosed of chronic kidney disease grade-5 with associated co-morbidities like type 2 diabetes mellitus, diabetic retinopathy and hypothyroidism was admitted for arteriovenous fistula construction. She was started on ferric carboxymaltose for the treatment of anaemia. She was given a test dose before administering the drug intravenously and she did not develop any reaction. The drug ferric carboxymaltose was then administered over a period of one hour. About half an hour after drug administration, the patient developed breathlessness and myalgia. After half hour of the above episode of breathlessness and myalgia. She also developed vomiting (one episode). Patient was managed with oxygen therapy, IV fluids and other drugs like corticosteroids, phenaramine maleate and nalbuphine which controlled the above symptoms. © 2014, Journal of Clinical and Diagnostic Research. All rights reserved.


Karanth S.S.,KMC Manipal | Gupta A.,KMC Manipal | Prabhu M.,KMC Manipal
Asian Pacific Journal of Tropical Medicine | Year: 2012

Dengue hemorrhagic fever is a more serious form of disease characterised by plasma leakage syndrome, thrombocytopenia and disseminated intravascular coagulation. We present a 51 year old male who presented with fever, petechiae and acute onset of breathlessness. Emergency chest rhoentogram showed a massive right sided pleural effusion. On insertion of intercostal drain, there was a sudden gush of blood tinged fluid suggestive of hemothorax. There was no history of trauma or bleeding tendencies. Laboratory investigations revealed a raised hematocrit and severe thrombocytopenia. Dengue IgM was surprisingly positive. After aggressive supportive management the patient gradually improved and was discharged. While bilateral pleural effusion is a known occurrence in dengue hemorrhagic fever, massive hemothorax is unheard of. We report the first case in literature of dengue hemorrhagic fever presenting as unilateral massive hemothorax. A suspicion of dengue must also be borne in mind in cases of non-traumatic hemothorax especially in endemic areas. © 2012 Hainan Medical College.


Poovathingal M.A.,KMC Manipal | Nagiri S.K.,KMC Manipal | Nagaraja,KMC Manipal
Asian Pacific Journal of Tropical Biomedicine | Year: 2014

Objective: To document the various clinical manifestations, lab parameters, complications and outcomes of Falciparum Malaria. The above data would be correlated with the parasitic index to deduce whether it would be an effective measure of the same. Methods: This was a prospective study among 183 inpatients aged above 18 from Kasturba Hospital, Manipal from May 2009 to January 2011. Ethical clearance was taken. Statistical analysis was done with the independent paired t test, linear correlation and Chi square test using SPSS 16. Results: In this study 78% cases were males. Most cases occurred during the monsoons. Fever was the major presentation with others being jaundice, vomiting and head ache. 50.8 % had complications, including hepatic dysfunction (40.9%), renal failure (19.13%), shock (7%), altered sensorium (9%), ARDS (3.27%) and severe anemia (1.63%). Hypoglycemia and gram negative sepsis were rare. Parasitic index, renal parameters and death were correlating positively. ESR was significantly related (P < 0.003) to complications and not to cerebral malaria. There were 12 mortalities out of which 9 were due to MODS and 3 due to ARDS. Conclusions: 50.8% cases conformed to the WHO definition of severe malaria indicating most present with complications. High parasite index and abnormal renal function are predictors of mortality and complications. Early diagnosis, anticipation of complications, close monitoring and combination therapy to over come drug resistance helps to contain the extent of mortality. © 2014 by the Asian Pacific Journal of Tropical Biomedicine.


PubMed | KMC Manipal
Type: Journal Article | Journal: Asian Pacific journal of tropical biomedicine | Year: 2014

To document the various clinical manifestations, lab parameters, complications and outcomes of Falciparum Malaria. The above data would be correlated with the parasitic index to deduce whether it would be an effective measure of the same.This was a prospective study among 183 inpatients aged above 18 from Kasturba Hospital, Manipal from May 2009 to January 2011. Ethical clearance was taken. Statistical analysis was done with the independent paired t test, linear correlation and Chi square test using SPSS 16.In this study 78% cases were males. Most cases occurred during the monsoons. Fever was the major presentation with others being jaundice, vomiting and head ache. 50.8 % had complications, including hepatic dysfunction (40.9%), renal failure (19.13%), shock (7%), altered sensorium (9%), ARDS (3.27%) and severe anemia (1.63%). Hypoglycemia and gram negative sepsis were rare. Parasitic index, renal parameters and death were correlating positively. ESR was significantly related (P<0.003) to complications and not to cerebral malaria. There were 12 mortalities out of which 9 were due to MODS and 3 due to ARDS.50.8% cases conformed to the WHO definition of severe malaria indicating most present with complications. High parasite index and abnormal renal function are predictors of mortality and complications. Early diagnosis, anticipation of complications, close monitoring and combination therapy to over come drug resistance helps to contain the extent of mortality.

Loading KMC Manipal collaborators
Loading KMC Manipal collaborators