Gillissen A.,Klinikum Am Steinenberg Ermstalklinik
Internistische Praxis | Year: 2017
Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation. The long-term goals are to achieve good symptom control, to minimize future risk of exacerbations, and side-effects of treatment. The treatment is adjusted in a continuous cycle of assessment, treatment, and review for the patient's response. Depending on asthma control therapy is escalated or deescalated within a 5 step ranging treatment plan. At each step different medication options are available starting with a short acting β2-agonist as needed in step 1, ending with systemic corticosteroids and/or biologics targeting specifically pro-inflammatory mediators in step 5. Pharmacologic therapy must be complemented with intervention strategies like allergen avoidance, cigarette smoke cessation, optimizing inhaler techniques and others. to reduce the future exacerbation risks. This review gives a cutting-edge summation of modern asthma therapy.