Bochenek-Cibor J.,Klinika Onkologii UJ CM |
Puskulluoglu M.,Klinika Onkologii UJ CM |
Zygulska A.,Klinika Onkologii UJ CM |
Krupinski M.,Krakowski Szpital Specjalistyczny im. Jana Pawla II |
Krzemieniecki K.,Klinika Onkologii UJ CM
Onkologia Polska | Year: 2012
Synovial sarcoma is a rare tumor, which has an unfavourable prognosis. The tumor presents three types (fibrous, epithelial and poorly differentiated) and is usually found in the soft tissue structures adjacent to the joints and tendons of the extremities of young patients. Authors report a case of the middle-aged female with a biphasic tumor of the right foot. The mass has been growing for years and at the time of the diagnosis, the disease was disseminated to the lungs. The primary tumor was excised and the patient started palliative systemic treatment. Due to the risk of superior vena cava obstruction after the 3rd cycle of the first-line anthracycline/dacarbazine-based chemotherapy she underwent radiation therapy. The second-line treatment containing ifosfamide was stopped after the 7th cycle because of the observed side effects. The patient now remains asymptomatic. Synovial sarcoma is intermediately sensitive to the cytotoxic agents, but hopes are laid upon targeted immunotherapies. Copyright © 2012 Cornetis.