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Taran K.,Katedra Patomorfologii | Bojanowska E.,Zaklad Patomorfologii Wieku Rozwojowego | Przewratil P.,Klinika Chirurgii i Onkologii Dzieciecej | Kobos J.,Zaklad Patomorfologii Wieku Rozwojowego
Family Medicine and Primary Care Review | Year: 2013

Background. Biology of vascular lesion in children (angiomas and vascular malformations) is not completely known. They appear among 2.5-3.5% of children and consist a serious problem of every day practice of both family doctors and specialists. Objectives. The aim of the study was to evaluate histoclinical features of childhood vascular lesions. Material and methods. 48 cases of vascular lesions were examined according to location and age and sex of the patients. Results. 33 capillary haemangiomas, 9 cavernous haemangiomas, 2 lymphangiomas and 4 vascular malformations were diagnosed. There was no predilection of sex or age. Statistically significant correlation between lesion type and location was found. Conclusions. Most of angiomas appear among boys and their location on the trunk is statistically significant. Real biology of childhood vascular lesions is still under discussion. © by Wydawnictwo Continuo.


Trelinska J.,University of Lodz | Stolarska M.,University of Lodz | Zalewska-Szewczyk B.,University of Lodz | Kuzanski W.,Klinika Chirurgii i Onkologii Dzieciecej | Mlynarski W.,University of Lodz
Onkologia Polska | Year: 2010

Bacteriophages belong to a group of viruses which can infect and destroy a bacterial host. In the antibiotic era they were not in use. But now, in the time of increasing prevalence of antibiotic-resistant microbes, there is a renewed interest in using bacteriophage therapy as a possible alternative for the treatment of bacterial infections. It is effective in all types of bacterial infections, especially those caused by pyogenic Staphylococci and Gram-negative bacteria. Two cases of bacteriophage therapy in Pseudomonas aeruginosa infections in children with acute leukemias were presented. In both patients bacteriophage therapy was used together with antibiotics and symptomatic treatment. Good results of therapy were observed. Presented examples show that phage therapy is a possible and effective aid for treatment of serious bacterial infections in immunocompromised patients. Copyright © 2010 Cornetis.


Jablonski J.,Klinika Chirurgii i Onkologii Dzieciecej | Jankowski Z.,Klinika Chirurgii i Onkologii Dzieciecej | Lewandowska M.,Zaklad Patomorfologii Wieku Rozwojowego | Andrzejewska E.,Klinika Chirurgii i Onkologii Dzieciecej
Family Medicine and Primary Care Review | Year: 2013

Background. The paper presents an author's own experience in use of bone cement with beta-tricalcium phosphate in the management of solitary bone cysts. Material and methods. The authors present results of treatment of 9 children with solitary bone cyst. All the patients were treated by cement based on beta-tricalcium phosphate injection of the bone cyst. The control postoperative X-rays were taken after 6 and 12 months. Results. Radiographic examination revealed indicating bone regeneration. Successful results were observed in all patients. There were no complications after treatment. Conclusions. The good results of treatment, minimally invasive operative management, no postoperative complications and a short hospital stay- encourage more widespread use of bone cement based on beta-tricalcium phosphate in treatment of solitary bone cysts. © by Wydawnictwo Continuo.


Taran K.,Katedra Patomorfologii | Wysocka A.,Klinika Chirurgii i Onkologii Dzieciecej | Sitkiewicz A.,Klinika Chirurgii i Onkologii Dzieciecej | Kobos J.,Zaklad Patomorfologii Wieku Rozwojowego
Family Medicine and Primary Care Review | Year: 2013

Background. Neuroblastoma is the most common solid tumor of childhood outside CNS. Treatment results are not satisfactory. Angiogenesis is a new prognostic marker in this group. Objectives. The aim of the study was to evaluate prognostic value of angiogenesis by comparison with histological type. Material and methods. 29 patients age from 14 days to 13 years were examined. 9 children died. Favorable histology was diagnosed in 18 cases, unfavorable in 11. Tumor tissue samples were stained routinely and used for immunohistochemical research with anti-CD34. CD34 expression was examined accordingto histological type oftumor and patients' survival. Results. In unfavorable tumors CD34 expression (with 'hot spots' pattern) was lower that among favorable ones. Conclusions. Angiogenesis is a potential prognostic marker in neuroblastoma and is modified by various and usually aggressive treatment methods. © Wydawnictwo Continuo.


Jankowski Z.,Klinika Chirurgii i Onkologii Dzieciecej | Jablonski J.,Klinika Chirurgii i Onkologii Dzieciecej | Lewandowska M.,Zaklad Patomorfologii Wieku Rozwojowego | Andrzejewska E.,Klinika Chirurgii i Onkologii Dzieciecej
Family Medicine and Primary Care Review | Year: 2013

Background. The authors present their experience with the diagnosis and treatment of children with primary nocturnal enuresis. Material and methods. The authors analysed 360 cases of patients reported between 2007 and 2012 with initial diagnosis of nocturnal enuresis. Results. In the study group the primary nocturnal enuresis was diagnosed in 118 patients. Non-pharmacological treatment was ineffective. Oxybutynin or desmopressin were used in the pharmacological treatment. Good results were obtained for 78 patients. Conclusions. 1. Finding the cause of nocturnal enuresis is important for the best results of treatment. 2. Early diagnosis and treatment in children with nocturnal enuresis may prevent the occurrence of emotional disorders, low self-esteem and poorer integration with other children. 3. The pharmacological treatment helps children with primary nocturnal enuresis to relieve this symptom. © by Wydawnictwo Continuo.

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