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Emeryk A.,Klinika Chorob Psluc i Reumatologii Dzieciecej | Cheslminska M.,Klinika Alergologii Katedry Pneumonologii i Alergologii | Krzych-Faslta E.,Zaksad Profilaktyki Zagrozen Srodowiskowych i Alergologii
Postepy Dermatologii i Alergologii | Year: 2010

Indications for nasal challenge tests with allergens are divided into diagnostic indications, pathophysiological indications and pharmacological indications. It is important to take the following factors into account to ensure that nasal challenge tests with allergens are carried out properly. Source

Specjalski K.,Klinika Alergologii Katedry Pneumonologii i Alergologii
Pneumonologia i Alergologia Polska | Year: 2010

Respiratory infections are one of the major causes of asthma exacerbations. Among numerous pathogens that may lead to exacerbations, particular attention should be paid to atypical bacteria: Chlamydia pneumoniae and Mycoplasma pneumoniae. Despite significant frequency, infections caused by these species are underestimated due to untypical clinical course and lack of easily accessible diagnostic tests. Although acute infection can be easily linked with deterioration of asthma control, the role of respiratory colonisation by Chlamydia pneumoniae or Mycoplasma pneumoniae has not been precisely defined. It is known that serologic signs of both past infection and chronic current infection (IgA) with Chlamydia pneumoniae or Mycoplasma pneumoniae are found more often in asthmatics compared to healthy controls. Besides respiratory colonisation by Chlamydia pneumoniae or Mycoplasma pneumoniae confirmed by culture or molecular tests is also more common in asthmatics. This is particularly relevant in cases of uncontrolled asthma that followed symptoms of respiratory infection. This may lead to the conclusion that atypical infections can play a role in asthma induction in previously healthy individuals as well as deteriorations in the course of the disease. Studies mentioned above have led to the new therapeutic possibility - eradication of Chlamydia pneumoniae. In some of the studies on eradication with macrolides promising results have been gained in terms of asthma control, but in most of the cases improvement was only temporary. © 2012 Via Medica. Source

Gruchala-Niedoszytko M.,Katedra Zywienia Klinicznego | Niedoszytko M.,Klinika Alergologii Katedry Pneumonologii i Alergologii | Chelminska M.,Klinika Alergologii Katedry Pneumonologii i Alergologii | Gorska A.,Klinika Alergologii Katedry Pneumonologii i Alergologii | And 3 more authors.
Alergia Astma Immunologia | Year: 2013

Introduction. Food allergy and intolerance present various symptoms, including severe anaphylactic reaction. Patients with mastocytosis are more susceptible to anaphylactic reactions. Aim. The aim of the study was to analyse the prevalence of food intolerance and food allergy among mastocytosis patients. Material and methods. The study group comprised 31 patients with mastocytosis diagnosed before 2007. Skin prick tests were performed in patients reporting food allergy and concentrations of sIgE against allergens selected using history-derived information were determined. The 5-year or longer follow-up made it possible to assess the effectiveness of the applied treatment. Results. Indolent systemic mastocytosis was diagnosed in 17(55%) of patients, 10 (32%) patients suffered from cutaneus mastocytosis and 4 (13%) were diagnosed with monoclonal mast cell activation syndrome. The symptoms of food intolerance were reported by 20 (65%) of patients, while IgE mediated food allergy was diagnosed in 9 (29%) of the subjects. Conclusions. Food intolerance is common among patients with ma-stocytosis, while correct diagnosis and treatment are necessary for the improvement of patient's clinical condition, particularly in cases involving anaphylactic shock reactions. © Alergia Astma Immunologia 2013. Source

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