Klinik fur Rinder

Hannover, Germany

Klinik fur Rinder

Hannover, Germany

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Furken C.,Klinik fur Rinder | Hoedemaker M.,Klinik fur Rinder
Tierarztliche Praxis Ausgabe G: Grosstiere - Nutztiere | Year: 2014

Objective: The effects of rumen-protected choline (RPC) on energy metabolism and milk production in dairy cows were analyzed. Material and methods: Two hundred and ninety-eight primiparous and multiparous cows of a high producing dairy herd (mean daily milk yield: 32 l) were randomly assigned to control or treatment groups and were fed with 0 or 15 g RPC, respectively, (corresponding to 0 and 60 g/d Rea Shure®, respectively) from 21 days before expected calving to 21 days postpartum (p. p.). Blood metabolites were determined for either all cows (glucose, -hydroxybutyrate [BHB]) or randomly (insulin, insulin-like growth factor-1 [IGF-1], non-esterified fatty acids [NEFA]) during the periparturient period. An index for insulin sensitivity (RQUICKI) was calculated and milk production data (dairy herd improvement tests, 100-days-, 305-days-, milk peak yield, colostrum quality) was analyzed. In the statistical analysis, a distinction was made between the feeding groups and between the parity, and their interactions were analyzed. Results: With the exception of a lower 305-day-milk yield in the treatment group (p < 0.05), the evaluated variables did not show statistically significant differences between the feeding groups and no interactions could be found. In comparison to heifers, multi parous cows had less cases of subclinical ketosis a. p. and p. p. (OR a. p.: 0.178; OR p. p.: 0.310), more of them were above the thre shold for somatic cell counts (OR 2.584-3.298), and their milk yields were higher (p < 0.05). Conclusion and clinical relevance: Supplementing RPC did not affect the energy metabolism or the milk pro duction in this herd. Further research in other dairy herds should focus on this topic. © Schattauer 2014.


Objective: To determine the effects of rumen-protected choline (RPC) on health and reproduction in dairy cows. Material and methods: A total of 298 primi- and multiparous German Holstein cows of a high-production dairy herd (average daily milk yield: 32 l) were assigned randomly to a control or treatment group and were hand fed with 0 or 60 g/d of RPC as ReaShure®, respectively, from 21 days before expected calving to 21 days post partum (p. p.) as a top dressing. Health data was analyzed for the incidence of fever within the first 10 days in milk (DIM) as well as the incidence of diseases and the culling rate within the first 200 DIM. Reproduction data were evaluated in terms of the calving data, uterine involution on days 10, 21 and 42 p. p., uterine cytology at day 42 p. p., progesterone concentrations during weeks 3 and 5 p. p. and certain fertility measures. In the statistical analysis, it was differentiated between the control and treatment groups and between primi- and multiparous animals, and their interactions were analyzed. Results: The treatment group had less cows with subclinical endometritis, higher sickness rates after day 100 p. p., lower numbers of stillbirths and more cyclic cows in week 5 p. p. compared to the control group (p < 0.05). Primipara in contrast to multipara had fever more frequently, higher rates of subclinical ketosis p. p., metritis and lameness, higher numbers of sick cows in the first 30 DIM, higher rates of stillbirths and dystocia, showed impaired involution of the uterus on day 10 p. p., fewer animals were cyclic during week 5 p. p. and less animals were culled (p < 0.05). Statistically significant interactions indicated that more heifers of the treatment group were lame, more heifers of the control group developed fever and subclinical endometritis, cows of the treatment group suffered more metritis and were sick more often in the first 30 DIM, and cows of the control group had more dystocia (p < 0.05). Conclusion: Overall, supplementing RPC had only minor effects on the health status and reproduction. Further research in other dairy herds should focus on this topic. © Schattauer 2014.


The group of environment-associated pathogens consists of bacteria which main reservoir is the environment. Coliform bacteria, Streptococcus uberis and enterococci belong to this group. Contamination takes place primarily between milking. However, infection occurs between milking as well as during milking. Due to a relatively short duration of infection, the herd prevalence is usually low. The bulk milk tank somatic cell count often is not increased because of frequent clinical mastitis. Strain differentiation typically reveals many different bacterial strains in a certain herd. However, there are also strains which have acquired the characteristics of cow-associated pathogens with a tendency to chronic infections. Because of their ubiquitous occurrence, cows constantly have to cope with environmental pathogens. Control measures include the prevention of new infection via reduction of contamination between and during milking. Important risk factors for contamination are the hygienic conditions in the barn and during milking. As to the latter, technical aspects such as vacuum stability and the risk of sudden air admission play a role. Furthermore, the local and systemic resistance are of importance, because they decide about the establishment and cause of infection. With regards to general resistance, stress-free housing conditions, adequate feeding (energy, fibre) and a good health management are necessary. With regards to the local resistance, acute and chronic teat changes which quite often can be linked to an inadequate milking procedure need to be considered. The dry period is a risk period for new infections, which can be prevented with long-term antibiotics or internal teat sealers. In summary, the control of mastitis caused by environmental pathogens requires a systematic approach. © M. & H. Schaper GmbH & Co.


Fleisch A.,University of Zürich | Piechotta M.,Klinik fur Rinder | Bollwein H.,University of Zürich | Janett F.,University of Zürich
Schweizer Archiv fur Tierheilkunde | Year: 2013

Fertility after treatment with Eazi-breed™ CIDR® G for 6 or 12 days outside the breeding season in Lacaune dairy sheep This study compares the fertility after short- and long-term synchronization using a progesterone in-travaginal device in Lacaune dairy sheep outside the breeding season. For the experiment 108 Lacaune sheep were treated with Eazi-breed™ CIDR® G intra-vaginal devices (Pfizer Animal Health, Zürich) for 12 days (Group L, n = 60) or 6 days (Group K, n = 48) in combination with eCG (Group L) or with eCG and 125 μg Cloprostenol (Group K) at device removal. Thereafter the ewes were kept together with rams for 60 days, ewes in estrus were recorded and the fertility was assessed after lambing. Blood progesterone concentration was measured at device application, withdrawal and 14 days later. Results show that neither treatment nor parity had an influence on estrus rate (Group L 91.7%, Group K 93.8%, nulli- and pluriparous animals 96.9% and 90.8%, respectively). Group L showed a tendency towards a better first cycle lambing rate and a significantly (P < 0.05) higher overall lambing rate compared to sheep of Group K (71.7% vs. 60.4% and 83.3% vs. 72.9%). Pluriparous ewes had higher (P < 0.05) lambing rates and greater (P < 0.05) numbers of lambs born per synchronized ewe than nulliparous sheep for the first cycle (75.0% vs. 46.9% and 1.4 ± 1.0 vs. 0.9 ± 1.1) as well as for the overall service period (92.1% vs. 46.9% and 1.7 ± 0.8 vs. 0.9 ± 1.1). Fourteen days after insert withdrawal progesterone concentrations were higher (P < 0.05) in Group L than in Group K (7.7 ± 4.3 vs. 5.6 ± 2.7 ng/ mL) and in nulli- compared to pluriparous (9.1 ± 5.6 vs. 5.7 ± 2.1 ng/mL) ewes. In conclusion, the overall lambing rate was higher after long-term compared to short progesterone treatment and nulliparous ewes were less suitable for estrus induction outside the breeding season. © 2013 Verlag Hans Huber, Hogrefe AG, Bern A. Fleisch et al.


Witt L.,Klinik fur Anasthesiologie und Intensivmedizin | Osthaus W.A.,Klinik fur Anasthesiologie und Intensivmedizin | Bunte C.,Klinik fur Anasthesiologie und Intensivmedizin | Teich N.,Klinik fur Anasthesiologie und Intensivmedizin | And 4 more authors.
Paediatric Anaesthesia | Year: 2010

Background: The recommendations for perioperative maintenance fluid in children have been adapted from hypotonic to isotonic electrolyte solutions with lower glucose concentrations (1-2.5% instead of 5%) to avoid hyponatremia or hyperglycemia. Objective: The objective of this prospective animal study was to determine the margin of safety of a novel isotonic-balanced electrolyte solution with 1% glucose (BS-G1) in comparison with normal saline with 1% glucose (NS-G1) in the case of accidental hyperhydration with a focus on acid-base electrolyte balance, glucose concentration, osmolality and intracranial pressure in piglets. Methods: Ten piglets (bodyweight 11.8 ± 1.8 kg) were randomly assigned to receive either 100 ml·kg -1 of BS-G1 or NS-G1 within one hour. Before, during and after fluid administration, electrolytes, lactate, hemoglobin, hematocrit, glucose, osmolality and acid-base parameters were measured. Results: Unlike BS-G1, administration of NS-G1 produced mild hyperchloremic acidosis (base excess BS-G1 vs NS-G1, baseline 1.9 ± 1.7 vs 2.9 ± 0.9 mmol·l -1, study end 0.2 ± 1.7 vs -2.7 ± 0.5 mmol·l -1, P < 0.05, chloride BS-G1 vs NS-G1 baseline 102.4 ± 3.4 vs 102.0 ± 0.7 mmol·l -1, study end 103.4 ± 1.8 vs 109.0 ± 1.4 mmol·l -1P < 0.05). The addition of 1% glucose led to moderate hyperglycemia (P < 0.05) with a concomitant increase in serum osmolality in both groups (P < 0.05). Conclusion: Both solutions showed a wide margin of safety in the case of accidental hyperhydration with less acid-base electrolyte changes when using BS-G1. This novel solution could therefore enhance patient's safety within the scope of perioperative volume management. © 2010 Blackwell Publishing Ltd.


Lietzau M.,Klinik fur Rinder | Rehage J.,Klinik fur Rinder | Heppelmann M.,Klinik fur Rinder
Tierarztliche Praxis Ausgabe G: Grosstiere - Nutztiere | Year: 2015

A 19-month-old Holstein-Friesian heifer displayed a circular swelling at the distal metacarpal area of the left forelimb with a compact, partially slightly fluctuating consistency. The animal exhibited no weight bearing of the affected limb. Radiological examinations of the fetlock area revealed a physeal osteomyelitis of the metacarpus. Surgical treatment involved a complete resection of the epiphyseal plate using a trephine. After immobilisation using a cast and repeated debridement of the wound cavities, the heifer was discharged with a slight lameness after 10 weeks. Half a year after surgical intervention no lameness was visible. © Schattauer 2015.


Grieger A.-S.,Mikrobiologie | Zoche-Golob V.,Mikrobiologie | Paduch J.-H.,Mikrobiologie | Hoedemaker M.,Klinik fur Rinder | Kromker V.,Mikrobiologie
Tierarztliche Praxis Ausgabe G: Grosstiere - Nutztiere | Year: 2014

Clinical mastitis as a frequently recurrent event can cause substantive economic loss on dairy farms. The reason for recurrent mastitis can be either a persistent infection of the bovine mammary gland by a mastitis pathogen or a reinfection of a quarter or udder after bacteriological cure. The virulence properties of a mastitis pathogen and the cure odds of an individual cow determine the development of persistent infections. Clinical episodes may alternate with periods without symptoms in the course of persistent infections. Strategies to reduce cases of recurrent mastitis have to include improved treatment concepts and measures to decrease new infection rates. The present literature review summarises the knowledge of definitions, frequencies, causes and effects of recurrent mastitis. © Schattauer 2014.


Cording F.,Mikrobiologie der Fakultat II | Hoedemaker M.,Klinik Fur Rinder | Kromker V.,Mikrobiologie der Fakultat II
Tierarztliche Praxis Ausgabe G: Grosstiere - Nutztiere | Year: 2013

Mastitis in cattle is an infection of the mammary gland caused by infection, toxins and/or trauma. Currently, it is assumed that there is a correlation between higher amounts of residual milk and the incidence of clinical mastitis. The amount of residual milk can be exa - mined using different methods. Higher amounts of residual milk may result from an insufficient teat condition and individual detachment settings of milking units. To date, scientific literature has already discussed the relationship between high amounts of residual milk, undermilking and the occurrence of clinical mastitis. The present paper reviews the current status of knowledge regarding residual milk and risk of mastitis. © 2013 Schattauer.


Pieper J.,Mikrobiologie der Fakultat II Maschinenbau und Bioverfahrenstechnik Hochschule Hanover | Hoedemaker M.,Klinik fur Rinder | Kromker V.,Mikrobiologie der Fakultat II Maschinenbau und Bioverfahrenstechnik Hochschule Hanover
Tierarztliche Praxis Ausgabe G: Grosstiere - Nutztiere | Year: 2013

The dry period poses an extraordinarily high risk of new infections for the bovine mammary gland. Environmental pathogens are of particular importance during this time. Normally, an infection during the dry period does not cause clinical symptoms, but is often responsible for clinical mastitis in the first weeks of lactation. Reducing new infections in dry cows can significantly decrease mastitis incidence in early lactation. During the course of the dry period, the new infection rate does not remain constant, but peaks immediately after drying off and shortly before calving. The chance of a new infection is influenced multifactorially by the animal, pathogen and environment. In this context, the closure of the teat canal using a keratin plug is very important. There are different approaches to antibiotic dry cow treatment. Either all udder quarters of all dry cows are treated (blanket dry-cow treatment) or just the udder of animals with a proven infection or an increased somatic cell count (selective dry-cow treatment). In the latter case, all udder quarters of an animal may be treated or just the one in which the infection or the increased somatic cell count was found. Instead of, or as a supplement to antibiotic treatment, teat sealers can be used. They support or take over the function of the keratin plug by closing the teat canal. In addition, there are some alternative methods to prevent new infections. Nevertheless, reducing the risk of infection is of primary importance. For this purpose, there are numerous options for improving hygiene in the environment of dry cows. © Schattauer 2013.


Bijmholt S.,Klinik fur Rinder | Muller K.,Klinik fur Rinder | Leiding C.,Besamungsverein Neustadt A. D. Aisch | Hoedemaker M.,Klinik fur Rinder | And 2 more authors.
Tierarztliche Praxis Ausgabe G: Grosstiere - Nutztiere | Year: 2012

Objective: The aim of this study was to assess lactation incidences of production diseases in German Fleckvieh cows. Material and methods: Investigations were carried out on six dairy farms (mean milk yield of herds 2008: 7834 ± 708 kg milk [mean ± SD]) in Bavaria. All farms kept the cows in free stall barns and fed them a total or partial mixed ration based on grass silage and corn silage. In total, 116 cows and 58 heifers were examined daily for 14 days post partum and treated - if necessary - according to standard protocols. The acquisition of data for diseases in the further lactation was carried out by regular visits to the farm as well as communication with the herd manager and the farm veterinarian. Results: Pluriparous cows suffered more frequently from production diseases (milk fever, retained placenta, clinical ketosis, ab - omasal displacement, metritis, endometritis, ovarian cysts, mastitis) than primiparous heifers: 33.3% and 46.4% of pluriparous and pri - miparous cows, respectively, remained clinically healthy, while 24.8% and 30.4%, respectively, suffered from one production disease during the first 2 weeks of lactation; more than one production disease was diagnosed in 41.9% and 23.2% of pluriparous and primiparous cows, respectively. The lactation incidences of production diseases varied considerably among pluriparous cows of the six farms: retained pla - centa 16.8 ± 13.2%, milk fever 15.1 ± 7.0%, clinical ketosis 16.8 ± 12.4%, metritis 3.8 ± 3.1%, abomasal displacement 1.1% (median 0.0; 0.0/0.0%), endometritis 11.7 ± 7.0%. Mastitis affected 56.0 ± 7.4% of the pluriparous cows, which experienced 1.7 mastitis episodes on average. At least one follicular cyst was diagnosed among 28.4 ± 8.6% of the cows. Lameness affected 18.5 ± 13.5% of pluriparous cows and heifers during the first 2 weeks of lactation. Conclusion: The lactation incidences of production diseases did not significantly differ from reference values reported for Holstein Friesian cows except the lower incidence of LDA among German Fleckvieh cows. The results indicate that the farm management affected lactation incidences of production diseases to a greater degree than additional factors, such as the breed of the cows. © Schattauer 2012.

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