Klinik fur Kleine Klauentiere

Hannover, Germany

Klinik fur Kleine Klauentiere

Hannover, Germany
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Ulrich R.,Institute For Pathologie | Buck B.,Klinik fur Kleine Klauentiere | Distl O.,Institute For Tierzucht Und Vererbungsforschung | Wohlsein P.,Institute For Pathologie
Tierarztliche Praxis Ausgabe G: Grosstiere - Nutztiere | Year: 2014

Tumours with skeletal-muscle differentiation are rare in companion animals. They are differentiated into benign rhabdomyomas and malignant rhabdomyosarcomas. A female German Holstein calf displayed a congenital, spherical, subcutaneous mass at the lateral side of the head. Histology revealed an encapsulated, expansile, highly cellular mass consisting of a reticular meshwork of moderately pleomorphic, small spindle-shaped to round cells within a fibrovascular to myxoid stroma as well as multifocal, large, blunt, multinucleated myotube-like cells (strap cells). Electron microscopy demonstrated characteristic cytoplasmic bundles of myofilaments and Z-stripes within the strap cells. Immunoreactivity for vimentin was observed in the small spindleshaped cells and for desmin in the strap cells. The results are consis -tent with the spectrum of findings characteristic for a bovine con -genital embryonal rhabdomyosarcoma. © Schattauer 2014.


Strobel H.,Tierarztpraxis Dr. Strobel | Moors E.,University of Gottingen | Ganter M.,Klinik fur Kleine Klauentiere | Spengler D.,Tierseuchenkasse Baden Wurttemberg | Voigt K.,Ludwig Maximilians University of Munich
Tierarztliche Praxis Ausgabe G: Grosstiere - Nutztiere | Year: 2012

Lameness in sheep induced by infectious agents can cause problems regarding animal welfare, diagnosis and treatment. Individual lame animals and lameness caused by systemic disease, but especially flock problems due to infectious causes of lameness, such as foot rot, can for various reasons pose a problem for veterinary treatment. The causes of lameness in sheep are described with a special focus on infectious flock problems, and the different treatment options such as foot trimming, foot baths and local and systemic antibiotic therapy as well as vaccination are discussed based on a review of recent international research. The limited choice of drugs licensed for use in sheep in Germany is highlighted. Treatment, therefore, often requires off-label use or the import of footbathing agents licensed in other European countries. The legal consequences of this lack of nationally licensed veterinary products in dealing with a "minor species" are discussed, with a final call for political solutions that will help improve this unsatisfactory situation. © Schattauer 2012.


Stau A.,Klinik fur kleine Klauentiere | Seelig B.,Tierarztliche Klinik Dr. Seelig | Walter D.,Tierarztliche Klinik Dr. Seelig | Schroeder C.,LDL Labor Diagnostik GmbH Leipzig | Ganter M.,Klinik fur kleine Klauentiere
Small Ruminant Research | Year: 2012

This study gives a first view into the current epidemiological situation of infections with Mycobacterium avium subsp. paratuberculosis (MAP) in German sheep and goat flocks. Furthermore, the correlation between the flock size and the flock seroprevalence of antibodies against MAP was investigated. On an individual basis, the correlation between body condition score (BCS), age and the serological status against MAP were calculated. For this purpose, the 10 skinniest animals in 167 German sheep and goat flocks were sampled. Serum samples from 1609 small ruminants were investigated for the presence of MAP antibodies using the commercial CATTLETYPE ® MAP Ab ELISA test kit (LDL - Labor Diagnostik Leipzig, Leipzig, Germany).The investigation revealed an overall individual MAP seroprevalence of 15% and a flock prevalence of 65%. Intra-flock prevalence in positive flocks was 22% (17% standard deviation (SD)). The intra-flock prevalence increased with the flock size, except for very large sheep flocks with more than 1000 ewes, but this correlation was not statistically significant. A low BCS correlated only in goats with a higher seroprevalence, not in sheep. No distinct correlation could be demonstrated between MAP serostatus and age. © 2012 Elsevier B.V.


Forsbach-Birk V.,University of Ulm | Foddis C.,University of Ulm | Simnacher U.,University of Ulm | Wilkat M.,University of Ulm | And 6 more authors.
PLoS ONE | Year: 2013

Enzootic abortion of ewes (EAE) due to infection with the obligate intracellular pathogen Chlamydia (C.) abortus is an important zoonosis leading to considerable economic loss to agriculture worldwide. The pathogen can be transmitted to humans and may lead to serious infection in pregnant women. Knowledge about epidemiology, clinical course and transmission to humans is hampered by the lack of reliable diagnostic tools. Immunoreactive proteins, which are expressed in infected animals and humans, may serve as novel candidates for diagnostic marker proteins and represent putative virulence factors. In order to broaden the spectrum of immunogenic C. abortus proteins we applied 2D immunoblot analysis and screening of an expression library using human and animal sera. We have identified 48 immunoreactive proteins representing potential diagnostic markers and also putative virulence factors, such as CAB080 (homologue of the "macrophage infectivity potentiator", MIP), CAB167 (homologue of the "translocated actin recruitment protein", TARP), CAB712 (homologue of the "chlamydial protease-like activity factor", CPAF), CAB776 (homologue of the "Polymorphic membrane protein D", PmpD), and the "hypothetical proteins" CAB063, CAB408 and CAB821, which are predicted to be type III secreted. We selected two putative virulence factors for further characterization, i.e. CAB080 (cMIP) and CAB063, and studied their expression profiles at transcript and protein levels. Analysis of the subcellular localization of both proteins throughout the developmental cycle revealed CAB063 being the first C. abortus protein shown to be translocated to the host cell nucleus. © 2013 Forsbach-Birk et al.


Von Altrock A.,Klinik Fur Kleine Klauentiere | Holtig D.,Klinik Fur Kleine Klauentiere
Tierarztliche Praxis Ausgabe G: Grosstiere - Nutztiere | Year: 2013

Skin alterations can be caused by both environmental conditions and diseases of the organism. Some diseases may only manifest in the skin while others represent signs of a generalized infection. Regarding their origin, skin diseases can be divided into congenital, infectious, and nutritional disorders, and those resulting from housing scarcities. Additionally, there are skin diseases with unknown causes. Skin diseases in a swine herd can result in economic losses through decreased feed efficiency and growth rate and increased mortality. The knowledge of causes and symptoms as well as the selection of appropriate further laboratory investigations provide a valid diagnosis and enable a quick and effective therapy. This description of several skin diseases should provide a background. © 2013 Schattauer.


Ganter M.,Klinik Fur Kleine Klauentiere
Tierarztliche Praxis Ausgabe G: Grosstiere - Nutztiere | Year: 2013

The epidemic occurrence of the Schmallenberg virus has induced numerous congenital malformations in small ruminants. Because of this high incidence of malformed lambs, an overview of the different causes of congenital malformations is provided. The most frequent infectious and physical causes as well as mineral and vitamin deficiencies and toxic agents which can induce congenital malformations are indicated. This list is supplemented by advice on sampling and laboratory diagnosis for an etiological diagnosis of the malformations. © 2013 Schattauer.


Koch R.,Anatomisches Institute | Hennig-Pauka I.,Klinik fur Kleine Klauentiere | Gasse H.,Anatomisches Institute
Pneumologie | Year: 2010

The histological composition of the Lamina propria in pigs especially in the cranial fold of the glottis gives reason to expect other phoniatric properties than in man. Age-related changes must be considered. © 2010 Georg Thieme Verlag KG Stuttgart New York.


Koch R.,Anatomisches Institute | Hennig-Pauka I.,Klinik fur Kleine Klauentiere | Gasse H.,Anatomisches Institute
Pneumologie | Year: 2010

The histological composition of the Lamina propria in pigs especially in the cranial fold of the glottis gives reason to expect other phoniatric properties than in man. Age-related changes must be considered. © Georg Thieme Verlag KG Stuttgart.


PubMed | Klinik fur kleine Klauentiere
Type: Case Reports | Journal: Berliner und Munchener tierarztliche Wochenschrift | Year: 2013

Skin tumors are rarely observed in pigs, and, in particular, only a few cases of squamous cell carcinoma have been reported. The present case report describes the occurrence of a squamous cell carcinoma located in the skin at the center of the udder of a 14-year-old German Landrace sow. The tumor was spherical and 17.0 cm in diameter. The tissue of the distal pole had a cauliflowerlike appearance, was black and ulcerated with a malodorous exudation. The sow did not show any signs of reduced general condition caused by the tumor. No evidence of metastasis was noted in regional lymph nodes and in the lung. The tumor, which weighed 2.4 kg, was surgically removed. The histopathology revealed infiltratively growing pleomorphic tumor cells and cell aggregations with prominent squamous differentiation. Cells were strongly positive for several cytokeratins by immunhistochemistry. The present findings confirmed the diagnosis of squamous cell carcinoma. After surgery, the sow recovered without complications and remained without recurrence at the follow-up three months later. This is the first report ofa squamous cell carcinoma in the skin in the udder in an old sow.


PubMed | Klinik fur kleine Klauentiere
Type: Journal Article | Journal: Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere | Year: 2012

The second part of the recommendations deals with the healthcare and the regulatory framework for the husbandry of sheep and goats. The suggested concept for healthcare aims to develop an individual health plan for every flock. This health plan focuses not only on the prevention of notifiable diseases, but also on chronic and slow infections as well as on parasite monitoring. The emphasis is on early detection of diseases and prophylaxis. In conjunction with this, the handling of lameness, shearing, animal trade and quarantine as well as cleaning and disinfection in sheep and goat flocks are intensively discussed. There are detailed federal and European legal regulations concerning the transport and the physical well-being of animals. These laws are clearly presented and advice for their practical implementation is provided.

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