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Chandwani P.,Heart and General Hospital | Prajapati J.,Apollo Hospitals International Ltd | Porwal S.,Kles Dr Prabhakar Kore Hospital And Medical Research Center | Khambhati B.,Sahajanand Medical Technologies Pvt. Ltd. | Thakkar A.,Sahajanand Medical Technologies Pvt. Ltd.
Journal of Clinical and Diagnostic Research | Year: 2015

Introduction: Coronary artery disease is the most common catastrophic disease in India. The safety and effectiveness of dual vessel sirolimus-eluting stent (SES) implantation (used as an intervention in CAD) is currently unknown in Indian population. The purpose of this study was to investigate one year clinical outcomes of patients with dual vessel coronary artery disease after implantation of the Supralimus-Core SES, in a "real-world" setting. Materials and Methods: We evaluated 60 patients between April-2011 and August-2012, who underwent dual vessel percutaneous coronary intervention (PCI) with the Supralimus-Core SES implantation at the same index procedure. Dual vessels were defined as involvement of two major epicardial vessels (right, left anterior descending, circumflex, or left main coronary arteries) or one major epicardial vessel and a branch (≥2.5 mm in diameter) originating from another major epicardial vessel. The primary endpoint was target lesion failure (TLF) defined as the composite of cardiac death, myocardial infarction (MI), and clinically-driven target lesion revascularization (TLR) at one year. Secondary endpoint included combined (definite, probable and possible) stent thrombosis (ST). Results: A total of 120 lesions were treated in 60 enrolled patients (mean age 56.0±9.2 y; 80.0% male) with average stent length of 23.1±8.5 mm. Among 60 patients, diabetes, hypertension and hypercholesterolemia were present in 15 (25.0%), 22 (36.7%) and 25 (41.7%) patients respectively. Indications for PCI were unstable angina in 30 (50.0%) patients and stable angina in 11 (18.3%) patients. Overall, 40 (33.3%) lesions were classified as complex (American College of Cardiology/American Heart Association type B2/C). The cumulative TLF rate was 5.0% (n=3) at one year. Cardiac death, MI and clinically-driven TLR occurred in 1 (1.7%), 0 (0%) and 2 (3.3%) patients, respectively at one year follow-up. The Kaplan-Meier curve of the freedom from overall events at one year was 95.0%. According to the Academic Research Consortium definition, there were no events of stent thrombosis during one year. Conclusion: Our study shows that, dual vessel Supralimus-Core SES implantation allows safe and effective treatment with low rates of TLF at one year follow-up in Indian population. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved. Source


Porwal S.C.,Kles Dr Prabhakar Kore Hospital And Medical Research Center | Halkati P.C.,Kles Dr Prabhakar Kore Hospital And Medical Research Center | Patted S.V.,Kles Dr Prabhakar Kore Hospital And Medical Research Center | Joshi A.,Kles Dr Prabhakar Kore Hospital And Medical Research Center
Journal of Cardiology Cases | Year: 2013

Stent dislodgement is a rare but recognized and potentially serious complication of percutaneous coronary intervention. Stent dislodgement was more frequent in the past when stents were manually crimped onto the balloon. Newer and improved balloon-mounted stents with better radio-opacity have reduced the incidence of stent dislodgement but do not completely eliminate it. We report a case of stent dislodgement which was successfully deployed with small-balloon technique. This patient however was successfully treated with small balloon technique at the desired site.<. Learning objective: Newer and improved balloon-mounted stents with better radio-opacity have reduced the incidence of stent dislodgement but do not completely eliminate it.>. © 2013 Japanese College of Cardiology. Source


Vyas N.,Kles Dr Prabhakar Kore Hospital And Medical Research Center | Ghatanatti R.,Kles Dr Prabhakar Kore Hospital And Medical Research Center | Nerlikar A.,Kles Dr Prabhakar Kore Hospital And Medical Research Center | Gan M.,Kles Dr Prabhakar Kore Hospital And Medical Research Center | Dixit M.,Kles Dr Prabhakar Kore Hospital And Medical Research Center
Journal of Clinical and Diagnostic Research | Year: 2016

Myxomas are the most common and potentially dangerous benign tumours of the heart. They may have either smooth or papillary surfaces and may have thrombus adherent. As both the papillary excrescences and the surface thrombi are friable in nature hence may undergo embolization. We report a case of left atrial myxoma, which underwent excision of the tumour for mitral valve obstructive features. In the immediate postoperative period patient developed ST elevation in lead II, III and aVF. Coronary angiogram revealed normal coronary pattern. Patient was treated with aspirin, heparin and IABP for 48 hours and recovered well. We conclude that there is a tendency for spontaneous recanalization of the obstructed coronary vessels by tumour emboli, hence patient can be managed conservatively. © 2016, Journal of Clinical and Diagnostic Research. All rights reserved. Source

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