News Article | May 4, 2017
Northern Westchester Hospital (NWH) will hold its Annual Benefit themed “Leading The Way, Together” on Saturday, November 18, 2017 at the Saw Mill Club, 77 Kensico Drive, Mt. Kisco, New York. The Hospital will pay tribute to physician honoree, David William Miller, MD, Chief of Anesthesiology and community honoree, Nancy Karch, Chair of Northern Westchester Hospital Board of Trustees. The benefit co-chairs are Albert and Doris Chance and Steven and Harriett Libov. “Dr. Miller and Nancy Karch exemplify the long-standing tradition of community engagement and steadfast leadership that have been constants since the founding of Northern Westchester Hospital over 100 years ago. They have been unstinting with their time, energy and expertise. Their generous intellectual contributions and financial support have helped position Northern Westchester Hospital as a leading regional provider, an innovator in the delivery of healthcare, and an unfaltering community resource,” says Joel Seligman, President & CEO, Northern Westchester Hospital. “Their dedication to the health and well-being of our community is commendable and an inspiration for many. It is with great pride that we honor them at our annual benefit.” Dr. Miller, a resident of Armonk, New York, and a MEDNAX-affiliated anesthesiologist, has served as Chief of Anesthesia at NWH since 2003. He is a member of the Northern Westchester Hospital Medical Board, Board of Trustees and Foundation Board. “During his tenure, Dr. Miller has recruited and mentored some of the most talented clinicians in the field. His commitment to excellence, high standards, state-of-the art technology and patient-centered care has helped create one of the region’s most outstanding surgical programs,” said Marla Koroly, MD, FACP, MBA, Chief Medical Officer and Senior Vice President of Medical Affairs, Northern Westchester Hospital. In addition, he and his wife Lauri are active philanthropists and benefactors of Northern Westchester Hospital, contributing to the Laurie Bass Sklaver Infusion Center and the Capital Campaign for the first phase of the Hospital’s Surgical Services Modernization, and donating to the Leukemia Society and the Ovarian Cancer Research Fund. “I am thrilled and grateful to be honored at this year’s benefit,” said Dr. Miller. “As both a member of the community and the clinical leadership team, I have immense pride in this institution. I’m humbled by the recognition, and thankful that I’m afforded the opportunity to contribute to the success of such a worthwhile organization.” Ms. Karch, a resident of Katonah, is a former Senior Partner of the international consulting firm McKinsey & Company where she spent 26 years; she joined the Northern Westchester Board of Trustees in 2006. Since then, she has been involved in some of the most consequential decisions in the Hospital’s history. She played a key role in the development of Northern Westchester Hospital’s strategic plan, as well as a new master plan for its campus which, last spring, resulted in the opening of six, new fully-integrated operating rooms and a new pre- and post-operative suite with 14 private bays. Under the leadership of immediate past Board Chair The Honorable Robert Spolzino, Ms. Karch chaired the committee that led the search for a new parent, culminating in January 2015, when Northern Westchester Hospital became part of Northwell Health, New York State’s largest healthcare system. When she became Chair of the Board in 2015, Ms. Karch led the transition, ensuring that Northern Westchester Hospital received effective representation within Northwell at the system level. In 2015, she was appointed to serve on Northwell Health’s Board of Trustees. “We are honoring Nancy Karch for her extraordinary leadership of and commitment to Northern Westchester Hospital. Nancy has given generously of her time and expertise to ensure this Hospital is well-positioned to meet the needs of our community for decades to come. As a well-respected leader in business and the nonprofit community, her philanthropic support is an endorsement and a testament to her commitment to the Hospital’s success: A commitment she’s shown for over 10 years,” said Mr. Seligman. Most recently, Ms. Karch has been leading the way as Northern Westchester Hospital redefines its role as a leader in community health and wellness and the impact the Hospital has outside its four walls. “Northern Westchester Hospital is exceptional. I am honored to be recognized by such an esteemed organization, and I’m even more grateful for the opportunity to contribute to its ever expanding excellence and positive impact on our community,” stated Ms. Karch. “The impact of high-quality care, the significance of engaged patients and families, the importance of supporting the caregiver, and the value of community wellness and education are understood and embraced by every staff member, enabling the hospital to serve its mission, and thrive. It is a privilege to be one of the many supporters of Northern Westchester Hospital and the Northwell Health System.” The “Leading The Way, Together” benefit will take place at the Saw Mill Club and the menu will be provided by Abigail Kirsch. Cocktails begin at 6:30 p.m. with dinner at 8 p.m. For additional information, please contact Gaby Golod Greenwald at 914.242.8392 or ggreenwald(at)northwell(dot)edu. About Northern Westchester Hospital Northern Westchester Hospital (NWH), a member of the Northwell Health, provides quality, patient-centered care that is close to home through a unique combination of medical expertise, leading-edge technology, and a commitment to humanity. Over 650 highly-skilled physicians, state-of-the-art technology and professional staff of caregivers are all in place to ensure that you and your family receive treatment in a caring, respectful and nurturing environment. NWH has established extensive internal quality measurements that surpass the standards defined by the Centers for Medicare & Medicaid Services (CMS) and the Hospital Quality Alliance (HQA) National Hospital Quality Measures. Our high-quality standards help to ensure that the treatment you receive at NWH is among the best in the nation. For more information, please visit http://www.nwhc.net and connect with us on Facebook. About Northwell Health Northwell Health is New York State’s largest health care provider and private employer, with 21 hospitals and over 550 outpatient facilities. We care for more than two million people annually in the metro New York area and beyond, thanks to philanthropic support from our communities. Our 61,000 employees – 15,000+ nurses and nearly 3,400 physicians, including nearly 2,700 members of Northwell Health Physician Partners -- are working to change health care for the better. We’re making breakthroughs in medicine at the Feinstein Institute. We're training the next generation of medical professionals at the visionary Hofstra Northwell School of Medicine and the School of Graduate Nursing and Physician Assistant Studies. And we offer health insurance through CareConnect. For information on our more than 100 medical specialties, visit Northwell.edu.
News Article | May 5, 2017
"Welltower has once again delivered a strong overall quarter," commented CEO Tom DeRosa. "Our premier seniors housing operators in high barrier to entry markets showed resiliency during a bad flu season and pockets of heightened supply nationwide, and were able to drive continued rate growth. We further executed on our strategy of deleveraging, while taking advantage of robust pricing to sell non-core assets in secondary markets at low cap rates. Our patience, discipline and the long-term nature of our decision making continues to drive shareholder value and best position Welltower for the compelling opportunities that lie ahead." On March 31, 2017, we had $380 million of cash and cash equivalents and $2.5 billion of available borrowing capacity under our primary unsecured credit facility. During the first quarter, we generated approximately $112 million in proceeds under our ATM and DRIP programs. In addition, we extinguished $806 million of secured debt at a blended average interest rate of 5.6%. In March, we redeemed all 11.5 million shares of our 6.5% Series J preferred stock. Net income attributable to common stockholders has been revised to a range of $2.39 to $2.49 per diluted share from the previous range of $2.65 to $2.75 per diluted share primarily due to the normalizing items in Exhibit 1. We are affirming our 2017 normalized FFO attributable to common stockholders guidance and expect to report in a range of $4.15 to $4.25 per diluted share. As previously disclosed, we will no longer report FAD, primarily because it could be considered a liquidity metric, but we will provide relevant data components. In preparing our guidance, we have updated the following assumptions: Our guidance does not include any additional investments, dispositions or capital transactions beyond what we have announced, nor any transaction costs, impairments, unanticipated additions to the loan loss reserve or other additional normalizing items. Please see the exhibits for a reconciliation of the outlook for net income available to common stockholders to FFO attributable to common stockholders. We will provide additional detail regarding our 2017 outlook and assumptions on the first quarter 2017 conference call. As previously announced, the Board of Directors declared a cash dividend for the quarter ended March 31, 2017 of $0.87 per share, as compared to $0.86 per share for the same period in 2016. On May 22, 2017, we will pay our 184th consecutive quarterly cash dividend. The declaration and payment of future quarterly dividends remains subject to review and approval by the Board of Directors. We completed $217 million of pro rata gross investments for the quarter including $104 million in acquisitions/JVs, $102 million in development funding and $11 million in loans. 100% of these investments were completed with existing relationships. Acquisitions/JVs were comprised of five separate transactions at a blended yield of 6.4%. The development fundings are expected to yield 7.5% upon stabilization and the loans were made at a blended rate of 8.0%. We also placed into service nine development projects totaling $186 million at a blended stabilized yield of 7.0%. Also during the quarter, we completed total dispositions of $1.1 billion consisting of loan payoffs of $65 million at an average yield of 8.7% and property sales of $1 billion at a blended yield on proceeds of 6.5%. We expanded our relationship with Benchmark by acquiring a 91-unit private pay seniors housing property through our existing 95/5 joint venture. The property opened in 2014 and is located in the New Haven, CT MSA. The purchase price based upon 100% ownership interest was $36 million, which represents a cap rate of 6.1%. The property was acquired through a purchase option that was granted to us after we provided a mezzanine loan for construction financing. Since closing our initial $846 million acquisition in 2011, we have completed $543 million of follow-on pro rata investments with Benchmark. We expanded our relationship with New Perspective by acquiring a 100% ownership interest in a 77-unit private pay seniors housing property owned by a third party and located in the Minneapolis/St. Paul MSA for $22 million. The property opened in 2015 and was added to a master lease which has a corporate guarantee and expires in 2030. The initial lease yield is 6.0% with 3% annual increasers. Since closing our initial $17 million acquisition/leaseback in 2009, we have completed $296 million of follow-on pro rata investments with New Perspective. We expanded our relationship with Avery by acquiring a 100% interest in two seniors housing properties in the UK midlands for £14.3 million. The properties will be added to a master lease at an initial lease yield of 7.5% with 3% annual increasers. The master lease has a corporate guarantee and expires in 2037. Since closing our initial $204 million acquisition/leaseback in 2013, we have completed $620 million of follow-on pro rata investments with Avery. We acquired a 100% interest in an affiliated outpatient medical office building in Anderson, Indiana for $22 million, which represents a year one cap rate of 6.3%. The property is 68,624 rentable square feet, was built in 2017, and is 100% master leased to Community Health Network (Moody's A2), a not-for-profit health system with over 1,400 affiliated physicians and 200 patient care sites throughout Central Indiana. Community Health Network leases over 160,000 square feet of space in Welltower properties. We expanded our relationship with Kisco by completing the development of 165 independent living units as part of a private pay, rental continuing care retirement community campus located in the North Hills area of Raleigh, NC. The investment amount based on 100% ownership interest was $72 million and the property was added to a master lease at an initial lease yield of 8.0% in our existing 85/15 joint venture. There are no increasers for the first five years and 25 basis point annual increasers thereafter. The assisted living, memory care and post-acute units will be completed during the second quarter. Since closing our initial $19 million acquisition in 2012, we have completed $137 million of follow-on investments with Kisco. We expanded our relationship with Sagora by completing the development of two private pay seniors housing properties located in Tulsa and Edmond, OK. The investment amount was $55 million and the properties were added to a master lease at an initial lease yield of 6.0%. There are outsized annual escalators for the first five years of the lease followed by 3% annual escalators thereafter. Since closing our initial $8.5 million acquisition in 2010, we have completed $430 million of follow-on investments with Sagora. We expanded our relationship with Legend by completing the development of two private pay seniors housing properties located in the Lancaster, PA MSA. The investment amount was $31 million and the properties were added to a master lease at an initial lease yield of 6.0%. There are outsized annual escalators for the first five years of the lease followed by 3% annual escalators. Since starting our initial $6 million development in 2005, we have completed $493 million of follow-on investments with Legend. We completed a 43,136 square foot development of an outpatient medical building in Wausau, Wisconsin that is 100% leased by Ministry Health Care (Moody's A2), a subsidiary of Ascension Health. The investment amount was $14 million and the yield on the development is 8.0%. Ascension Health leases over 250,000 square feet of space in Welltower properties. We completed a 56,786 square foot development of an outpatient medical building on Centura's Castle Rock Adventist Health Campus in the Denver MSA that was 65% leased at opening. The investment amount was $12 million and the stabilized yield on the development is 9.1%. We completed the previously announced sale of a 75% interest in 11 Brookdale communities at a valuation of $268.5 million (based on a 100% ownership interest), which represents a 5.75% cap rate on in-place rent. The portfolio was added to an existing joint venture where Cindat/Union Life owns a 75% interest and Welltower retains a 25% stake. We realized a gain on sale of $42 million. We completed the disposition of 26 senior housing properties operated by and leased to Senior Lifestyle for $753 million. We realized a gain on sale of $169 million and an unlevered IRR of 11.1%. We completed the disposition of six long-term/post-acute facilities pursuant to a purchase option in our lease agreement for $72 million, which represents an 8.9% cap on in-place rent. We realized a gain on sale of $20 million and an unlevered IRR of 12.8%. We completed the disposition of a seniors housing operating property with 183 units located in Victoria, British Columbia, Canada. The property was 100% owned by Welltower and third party managed by Chartwell. The property was sold for $27.5 million, which represents a 4.8% cap on in-place NOI. We realized a gain on sale of $13 million and an unlevered IRR of 16.2%. We have scheduled a conference call on Friday, May 5, 2017 at 10:00 a.m. Eastern Time to discuss our first quarter 2017 results, industry trends, portfolio performance and outlook for 2017. Telephone access will be available by dialing 888-346-2469 or 706-758-4923 (international). For those unable to listen to the call live, a taped rebroadcast will be available beginning two hours after completion of the call through May 19, 2017. To access the rebroadcast, dial 855-859-2056 or 404-537-3406 (international). The conference ID number is 3098658. To participate in the webcast, log on to www.welltower.com 15 minutes before the call to download the necessary software. Replays will be available for 90 days. We believe that revenues, net operating income from continuing operations (NOICO), net income and net income attributable to common stockholders (NICS), as defined by U.S. generally accepted accounting principles (U.S. GAAP), are the most appropriate earnings measurements. However, we consider funds from operations (FFO), same store net operating income (SSNOI), same store revenues per occupied room (SS REVPOR), and Adjusted EBITDA (A-EBITDA) to be useful supplemental measures of our operating performance. Excluding A-EBITDA, these supplemental measures are disclosed on our pro rata ownership basis. Pro rata amounts are derived by reducing consolidated amounts for minority partners' noncontrolling ownership interests and adding our minority ownership share of unconsolidated amounts. We do not control unconsolidated investments. While we consider pro rata disclosures useful, they may not accurately depict the legal and economic implications of our joint venture arrangements and should be used with caution. Historical cost accounting for real estate assets in accordance with U.S. GAAP implicitly assumes that the value of real estate assets diminishes predictably over time as evidenced by the provision for depreciation. However, since real estate values have historically risen or fallen with market conditions, many industry investors and analysts have considered presentations of operating results for real estate companies that use historical cost accounting to be insufficient. In response, the National Association of Real Estate Investment Trusts (NAREIT) created FFO as a supplemental measure of operating performance for REITs that excludes historical cost depreciation from net income. FFO attributable to common stockholders, as defined by NAREIT, means net income attributable to common stockholders, computed in accordance with U.S. GAAP, excluding gains (or losses) from sales of real estate and impairments of depreciable assets, plus real estate depreciation and amortization, and after adjustments for unconsolidated entities and noncontrolling interests. Normalized FFO attributable to common stockholders represents FFO attributable to common stockholders adjusted for certain items detailed in Exhibit 1. We believe that normalized FFO attributable to common stockholders is a useful supplemental measure of operating performance because investors and equity analysts may use this measure to compare the operating performance of the company between periods or as compared to other REITs or other companies on a consistent basis without having to account for differences caused by unanticipated and/or incalculable items. As discussed in Note 17 to our consolidated financial statements, NOICO is used to evaluate the operating performance of our properties. We define NOI as the pro rata version of NOICO which is total revenues, including tenant reimbursements, less property operating expenses. Property operating expenses represent costs associated with managing, maintaining and servicing tenants for our seniors housing operating and outpatient medical properties. These expenses include, but are not limited to, property-related payroll and benefits, property management fees, marketing, housekeeping, food service, maintenance, utilities, property taxes and insurance. General and administrative expenses represent costs unrelated to property operations or transaction costs. These expenses include, but are not limited to, payroll and benefits, professional services, office expenses and depreciation of corporate fixed assets. SSNOI is used to evaluate the operating performance of our properties under a consistent population which eliminates changes in the composition of our portfolio. As used herein, same store is generally defined as those revenue-generating properties in the portfolio for the relevant year-over-year reporting periods. Land parcels, loans and sub-leases as well as any properties acquired, developed/redeveloped, transitioned, sold or classified as held for sale during that period are excluded from the same store amounts. Normalizers include adjustments that in management's opinion are appropriate in considering SSNOI, a supplemental, non-GAAP performance measure. None of these adjustments, which may increase or decrease SSNOI, are reflected in our financial statements prepared in accordance with U.S. GAAP. Significant normalizers (defined as any that individually exceed 0.50% of SSNOI growth per property type) are separately disclosed and explained in the relevant supplemental information package. We believe SSNOI provides investors relevant and useful information because it measures the operating performance of our properties at the property level on an unleveraged basis. No reconciliation of the forecasted range for SSNOI on a combined or segment basis for fiscal year 2017 is included in this release because we are unable to quantify certain amounts that would be required to be included in the comparable GAAP financial measure without unreasonable efforts, and we believe such reconciliation would imply a degree of precision that could be confusing or misleading to investors. REVPOR represents the average revenues generated per occupied room per month at our seniors housing operating properties. It is calculated as the pro rata version of resident fees and services revenues per the income statement divided by average monthly occupied room days. SS REVPOR is used to evaluate the REVPOR performance of our properties under a consistent population which eliminates changes in the composition of our portfolio. It based on the same pool of properties used for SSNOI and includes any revenue normalizations used for SSNOI. We use REVPOR and SS REVPOR to evaluate the revenue-generating capacity and profit potential of our seniors housing operating portfolio independent of fluctuating occupancy rates. They are also used in comparison against industry and competitor statistics, if known, to evaluate the quality of our seniors housing operating portfolio. We measure our credit strength both in terms of leverage ratios and coverage ratios. The leverage ratios indicate how much of our balance sheet capitalization is related to long-term debt, net of cash and IRC section 1031 deposits. We expect to maintain capitalization ratios and coverage ratios sufficient to maintain a capital structure consistent with our current profile. The coverage ratios are based on EBITDA which stands for earnings (net income per income statement) before interest expense, income taxes, depreciation and amortization. Covenants in our senior unsecured notes contain financial ratios based on a definition of EBITDA that is specific to those agreements. Failure to satisfy these covenants could result in an event of default that could have a material adverse impact on our cost and availability of capital, which could in turn have a material adverse impact on our consolidated results of operations, liquidity and/or financial condition. Due to the materiality of these debt agreements and the financial covenants, we have defined A-EBITDA to exclude unconsolidated entities and to include adjustments for stock-based compensation expense, provision for loan losses, gains/losses on extinguishment of debt, transactions costs, gains/losses/impairments on properties, gains/losses on derivatives and other non-recurring and/or non-cash income/charges. We believe that A-EBITDA, along with net income and cash flow provided from operating activities, is an important supplemental measure because it provides additional information to assess and evaluate the performance of our operations. Our leverage ratios include undepreciated book capitalization and net debt to A-EBITDA. Undepreciated book capitalization represents book capitalization adjusted for accumulated depreciation and amortization. Book capitalization represents the sum of net debt (defined as total long-term debt less cash and cash equivalents and any IRC section 1031 deposits), total equity and redeemable noncontrolling interests. Our leverage ratios are defined as the proportion of net debt to total capitalization. Our supplemental reporting measures and similarly entitled financial measures are widely used by investors, equity and debt analysts and ratings agencies in the valuation, comparison, rating and investment recommendations of companies. Our management uses these financial measures to facilitate internal and external comparisons to historical operating results and in making operating decisions. Additionally, they are utilized by the Board of Directors to evaluate management. The supplemental reporting measures do not represent net income or cash flow provided from operating activities as determined in accordance with U.S. GAAP and should not be considered as alternative measures of profitability or liquidity. Finally, the supplemental reporting measures, as defined by us, may not be comparable to similarly entitled items reported by other real estate investment trusts or other companies. Please see the exhibits for reconciliations of supplemental reporting measures and the supplemental information package for the quarter ended March 31, 2017, which is available on the company's website (www.welltower.com), for information and reconciliations of additional supplemental reporting measures. Welltower Inc. (NYSE: HCN), an S&P 500 company headquartered in Toledo, Ohio, is driving the transformation of health care infrastructure. The company invests with leading seniors housing operators, post-acute providers and health systems to fund the real estate infrastructure needed to scale innovative care delivery models and improve people's wellness and overall health care experience. Welltower™, a real estate investment trust ("REIT"), owns interests in properties concentrated in major, high-growth markets in the United States, Canada and the United Kingdom, consisting of seniors housing and post-acute communities and outpatient medical properties. More information is available at www.welltower.com. We routinely post important information on our website at www.welltower.com in the "Investors" section, including corporate and investor presentations and financial information. We intend to use our website as a means of disclosing material, non-public information and for complying with our disclosure obligations under Regulation FD. Such disclosures will be included on our website under the heading "Investors". Accordingly, investors should monitor such portion of the company's website in addition to following our press releases, public conference calls and filings with the Securities and Exchange Commission. The information on our website is not incorporated by reference in this press release, and our web address is included as an inactive textual reference only. This press release contains "forward-looking statements" as defined in the Private Securities Litigation Reform Act of 1995. When we use words such as "may," "will," "intend," "should," "believe," "expect," "anticipate," "project," "pro forma," "estimate" or similar expressions that do not relate solely to historical matters, we are making forward-looking statements. In particular, these forward-looking statements include, but are not limited to, those relating to our opportunities to acquire, develop or sell properties; our ability to close anticipated acquisitions, investments or dispositions on currently anticipated terms, or within currently anticipated timeframes; the expected performance of our operators/tenants and properties; our expected occupancy rates; our ability to declare and to make distributions to shareholders; our investment and financing opportunities and plans; our continued qualification as a REIT; our ability to access capital markets or other sources of funds; and our ability to meet our earnings guidance. Forward-looking statements are not guarantees of future performance and involve risks and uncertainties that may cause our actual results to differ materially from our expectations discussed in the forward-looking statements. This may be a result of various factors, including, but not limited to: the status of the economy; the status of capital markets, including availability and cost of capital; issues facing the health care industry, including compliance with, and changes to, regulations and payment policies, responding to government investigations and punitive settlements and operators'/tenants' difficulty in cost-effectively obtaining and maintaining adequate liability and other insurance; changes in financing terms; competition within the health care and seniors housing industries; negative developments in the operating results or financial condition of operators/tenants, including, but not limited to, their ability to pay rent and repay loans; our ability to transition or sell properties with profitable results; the failure to make new investments or acquisitions as and when anticipated; natural disasters and other acts of God affecting our properties; our ability to re-lease space at similar rates as vacancies occur; our ability to timely reinvest sale proceeds at similar rates to assets sold; operator/tenant or joint venture partner bankruptcies or insolvencies; the cooperation of joint venture partners; government regulations affecting Medicare and Medicaid reimbursement rates and operational requirements; liability or contract claims by or against operators/tenants; unanticipated difficulties and/or expenditures relating to future investments or acquisitions; environmental laws affecting our properties; changes in rules or practices governing our financial reporting; the movement of U.S. and foreign currency exchange rates; our ability to maintain our qualification as a REIT; key management personnel recruitment and retention; and other risks described in our reports filed from time to time with the Securities and Exchange Commission. Finally, we undertake no obligation to update or revise publicly any forward-looking statements, whether because of new information, future events or otherwise, or to update the reasons why actual results could differ from those projected in any forward-looking statements. To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/welltower-reports-first-quarter-2017-results-300452245.html
News Article | May 1, 2017
Patients in need of an emergency root canal in White Plains, NY can turn to Advanced Endodontics of Westchester for state-of-the-art endodontics. Drs. Justin Kolnick, Kara Diamond, Randall Barton, Keith Hope and Bilal Chaudhry apply modern techniques using the latest technology for a variety of endodontic procedures. Delaying emergency dental care, including root canals, may only lead to additional issues and prolonged pain. However, for those with dental fear, receiving the treatment necessary is a difficult experience in itself. To allay their patients’ fears, the endodontists at Advanced Endodontics of Westchester provide sedation dentistry and minimally invasive laser endodontics to reduce recovery time and minimize discomfort. Tooth pain can dramatically affect a patient’s life. An infected tooth typically causes a substantial level of discomfort, ranging from sensitivity to heat and cold to throbbing pain that worsens in a reclined position. By the time the symptoms become severe, many patients are forced to seek emergency dental care. The endodontists at Advanced Endodontics of Westchester understand the urgency of treatment at this stage, which is why they offer cutting-edge emergency services 24 hours a day, seven days a week. With the right care, many teeth can be saved using microscope- and laser-assisted root canal techniques. The goal of this procedure is to remove the infected nerve tissue so that the pain is eliminated while also saving the tooth. Using dental lasers, the Advanced Endodontics of Westchester team can avoid causing unnecessary damage to patients’ teeth and effectively target and eradicate infection in a tooth, leaving healthy teeth preserved. The laser also disinfects more thoroughly, and the highly calibrated beam of light coupled with a stream of water is so gentle, it virtually eliminates the need for anesthetic. However, even though the physical trauma of the procedure is lessened significantly by the laser, patients who are anxious about undergoing a root canal in White Plains, NY, can opt for individualized sedation dentistry treatment to put them at ease throughout the process. More information about the benefits of laser treatments and sedation dentistry is available at http://www.westchesterendo.com. Patients in White Plains, NY, who want to schedule an appointment or receive emergency dental care can call 914-750-4033. For treatment at the Mt. Kisco location, individuals can call 914-750-4034. Advanced Endodontics of Westchester is a dental practice offering personalized endodontic dental care to patients from two office locations, in White Plains and Mt. Kisco, NY. Drs. Justin Kolnick, Kara Diamond, Randall Barton, Keith Hope and Bilal Chaudhry proudly serve their community with the latest advancements in dentistry to ensure each patient leaves with the oral care they need. To learn more about the services offered at Advanced Endodontics of Westchester visit their website at http://www.westchesterendo.com or call 914-750-4033 to schedule an appointment at the White Plains, NY location and 914-750-4034 for the Mt. Kisco, NY location.
News Article | April 17, 2017
New patients interested in receiving effective, gentle laser dentistry in White Plains or Mt. Kisco NY, can now be treated with Low Level Laser Therapy (LLLT) at Advanced Endodontics of Westchester. Drs. Justin Kolnick, Kara Diamond, Randall Barton, Keith Hope and Bilal Chaudhry are experienced endodontists who recently acquired the THOR laser, as well as received official training to provide this cutting-edge treatment. This laser technology allows them to reduce pain and inflammation as well as improve tissue repair for a variety of endodontic treatments and dental conditions. LLLT uses laser or LED light to facilitate tissue repair, decrease pain and minimize inflammation wherever applied. Frequently used before and after a variety of dental procedures, the THOR laser has been shown to drastically reduce pain in patients, limit the need of pain medication and provide the relief they need to see a successful outcome. It is effective in treating nerves, muscles, bones, skin wounds and tendons. Drs. Kolnick, Diamond, Barton, Hope and Chaudhry utilize this powerful laser technology to relieve trigger points within jaw muscles, treat neuropathic pain and relieve discomfort from TMJ (temporomandibular joint) issues. The THOR laser can also be used for a host of other oral diseases that cause inflammation and pain. LLLT Is frequently utilized after root canal treatments and root end surgeries. The intensity and wavelength of the laser can be adjusted to obtain the ideal amount of laser concentration in a given treatment area and be customized for each patient. The Endodontics of Westchester team encourages patients who are nervous about LLLT and laser dentistry to learn more about its many benefits by scheduling a personalized consultation to speak with an experienced endodontist. Drs. Kolnick, Diamond, Barton, Hope and Chaudhry invite new patients to schedule appointments for LLLT and laser dentistry at their White Plains, or Mt. Kisco, NY practice locations. Patients are also encouraged to visit http://www.westchesterendo.com for more information. Advanced Endodontics of Westchester is a dental practice offering personalized endodontic dental care to patients from two office locations, in White Plains and Mt. Kisco, NY. Drs. Justin Kolnick, Kara Diamond, Randall Barton, Keith Hope and Bilal Chaudhry proudly serve their community with the latest advancements in dentistry to ensure each patient leaves with the oral care they need. To learn more about the services offered at Advanced Endodontics of Westchester visit their website at http://www.westchesterendo.com or call (914) 750-4033 to schedule an appointment at the White Plains, NY location and (914) 750-4034 for the Mt. Kisco, NY location.
News Article | April 17, 2017
Drs. Justin Kolnick, Kara Diamond, Randall Barton, Keith Hope and Bilal Chaudhry are honoring Root Canal Awareness Week by teaching their patients about the key role this treatment plays in protecting oral health, along with the benefits of receiving root canal therapy from an experienced endodontist. To better serve those who need a root canal in White Plains, NY or their second location in Mt. Kisco, NY, the doctors are also accepting new patients to their practice, Advanced Endodontics of Westchester, with or without referrals. Root canal therapy is a procedure to remove infection from the inside of a damaged or decaying tooth. During this treatment, the root canal system is thoroughly cleaned and then sealed to prevent further infection, damage, pain and sensitivity. To ensure effective treatment for each patient, the doctors at Advanced Endodontics of Westchester offer endodontic microsurgery in addition to performing basic cleaning of the root canal in White Plains, NY. Microsurgery allows the doctors to treat infections at the base of the root canal in cases when traditional therapy is not an effective option. Since Drs. Kolnick, Diamond, Barton, Hope and Chaudhry specialize in endodontic procedures, patients who visit Advanced Endodontics of Westchester can expect minimal complications and a high success rate. On average, endodontists perform 25 root canals per week, whereas a general dentist may perform less than five. Advanced Endodontics of Westchester is not only committed to providing the latest techniques, this team also has a dedicated microsurgery center, allowing the doctors to perform sedation dentistry and endodontic microsurgery on-site. The doctors also use leading technology, such as surgical microscopes, to improve accuracy and eliminate unnecessary tissue trauma. People who notice symptoms such as tooth pain are encouraged to visit Advanced Endodontics of Westchester to determine whether they may benefit from a root canal in White Plains, NY. New patients may request appointments with an endodontist by visiting the practice website, http://www.westchesterendo.com, or by calling the White Plains office directly at 914-750-4033 or 914-750-4034 for their Mt. Kisco location. Advanced Endodontics of Westchester is a dental practice offering personalized endodontic dental care to patients from two office locations, in White Plains and Mt. Kisco, NY. Drs. Justin Kolnick, Kara Diamond, Randall Barton, Keith Hope and Bilal Chaudhry proudly serve their community with the latest advancements in dentistry to ensure each patient leaves with the oral care they need. To learn more about the services offered at Advanced Endodontics of Westchester visit their website at http://www.westchesterendo.com or call (914) 750-4033 to schedule an appointment at the White Plains, NY location and (914) 750-4034 for the Mt. Kisco, NY location.
News Article | April 17, 2017
Patients in need of endodontic services from a qualified endodontist in Mt. Kisco, NY, can now receive minimally invasive treatment at Advanced Endodontics of Westchester, with or without a referral. Drs. Justin Kolnick, Kara Diamond, Randall Barton, Keith Hope and Bilal Chaudhry are educating patients on the importance of seeing a trained professional who offers a conservative approach to root canal procedures. Using this less invasive strategy to traditional treatment, the Advanced Endodontics of Westchester team preserves more of the tooth structure, and as a result, the life of a tooth. A root canal is designed to remove decayed tissue from the root of a tooth and replace it with specialized material. When the pulp of the tooth becomes infected or inflamed, it is usually necessary to perform endodontic treatments. If left untreated, inflammation of the pulp inside the root canal can lead to severe pain or an abscess. Patients may need endodontic treatments if they notice increased and prolonged tooth sensitivity to heat or cold, swelling in the gums, tenderness when chewing, unexplained pain in the tooth or the area around the tooth. In rare cases, no obvious symptoms are present and the need for a root canal can only be diagnosed by X-rays or other scans of the oral structures. The team at Advanced Endodontics of Westchester uses a conservative approach to root canals to preserve more of each patient’s natural tooth. Implementing this gentle method minimizes the removal of healthy dentin while creating enough space to treat and fill the infected area properly. This technique decreases the risk of fractures and damage to the tooth while also providing patients with more options for final restorations. By preserving as much natural bone as possible, minimally invasive endodontic procedures help teeth last longer. Advanced Endodontics of Westchester offers advanced training and technology to improve endodontic treatment success. Applying a surgical endodontic microscope, laser dentistry, Cone Beam CT imaging and a dedicated microsurgery center, this team is dedicated to ensuring patients receive leading-edge and minimally invasive care. Patients interested in receiving a minimally invasive root canal by an endodontist in Mt. Kisco, NY, are encouraged to schedule an appointment at Advanced Endodontics of Westchester by calling 914-750-4034 for the Mt. Kisco location, or 914-750-4033 for the White Plains, NY office. Advanced Endodontics of Westchester is a dental practice offering personalized endodontic dental care to patients from two office locations, in White Plains and Mt. Kisco, NY. Drs. Justin Kolnick, Kara Diamond, Randall Barton, Keith Hope and Bilal Chaudhry proudly serve their community with the latest advancements in dentistry to ensure each patient leaves with the oral care they need. To learn more about the services offered at Advanced Endodontics of Westchester visit their website at http://www.westchesterendo.com or call 914-750-4033 to schedule an appointment at the White Plains, NY location and 914-750-4034 for the Mt. Kisco, NY location.
Saikusa K.,Yokohama City University |
Fuchigami S.,Yokohama City University |
Takahashi K.,Yokohama City University |
Takahashi K.,Chugai Research Institute for Medical Science Inc. |
And 8 more authors.
Analytical Chemistry | Year: 2013
The minimum structural unit of chromatin is the nucleosome core particle (NCP), consisting of 146 bp of DNA wrapped around a histone octamer, which itself contains two H2A/H2B dimers and one (H3/H4)2 tetramer. These multimers possess functionally important tail regions that are intrinsically disordered. In order to elucidate the mechanisms behind NCP assembly and disassembly processes, which are highly related to gene expression, structural characterization of the H2A/H2B dimer and (H3/H4)2 tetramer will be of importance. In the present study, human histone multimers with disordered tail regions were characterized by electrospray ionization (ESI) ion mobility-mass spectrometry (IM-MS) and molecular dynamics (MD) simulation. Experimentally obtained arrival times of these histone multimer ions showed rather wide distributions, implying that multiple conformers exist for each histone multimer in the gas phase. To examine their structures, MD simulations of the histone multimers were performed first in solution and then in vacuo at four temperatures, resulting in a variety of histone multimer structures. Theoretical collision cross-section (CCS) values calculated for the simulated structures revealed that structural models with smaller CCS values had more compact tail regions than those with larger CCS values. This implied that variation of the CCS values of the histone multimers were primarily due to the random behaviors of the tail regions in the gas phase. The combination of IM-MS and MD simulation enabled clear and comprehensive characterization of the gas-phase structures of histone multimers containing disordered tails. © 2013 American Chemical Society.
News Article | December 8, 2016
Persistence Market Research digs deep into the global guerbet alcohols market and fetches some key information through structured market research. The report, "Global Market Study on Guerbet Alcohols: 2-octyldodecanol Product Type Segment Projected to Account for Significant Market Share Between 2016 and 2024 " gauges the market and predicts the future demographic and climactic changes of the market. The report reveals that the 2-octyldodecanol segment will dominate more than 35% market share and it will surge at a CAGR of 6.7% by the end of the forecast period (2016 - 2024). The present estimated value of the global guerbet alcohols market is more than US$ 800 Mn and the market will stretch at a CAGR of 5.6% by 2024. A massive boom in the beauty and cosmetics industry and enhanced beauty and conscious customers are populating the global market. A host of high-end beauty products and cosmetics are a part of the daily lives of the millions. The need and emergence of the multifunctional cosmetics are also soaring in the global cosmetics market and thus it is creating a suitable ambience of growth for the global guerbet alcohols market. The new breed of multifunctional cosmetics has the ability to control and omit some of the acute skin problems are high in demand. They are geared to deal with problems such as anti-aging and they also have the ability to provide a shied from UV rays, they are an excellent anti-oxidant, moisturizers and also possess the capability of cleaning the skin. The significant rise in the market of the multifunctional cosmetics will push the global guerbet alcohol market ahead within the forecast period. The guerbet alcohols are safer alternatives and thus their popularity within the cosmetic fraternity immense. The genetic qualities of guerbet alcohols helps them gain an edge in the market. They are excellent flattening and good perfuming agents and they are also an able emulsion stabilizer which makes them an obvious choice for some of the leading cosmetic giants spread across the globe. The overall cost of the production of the guerbet alcohols are extremely high. A suitable production of the alcohol needs proper care and precaution and goes through a series of processes before reaching the final step. This long and extensive process of manufacturing of alcohol is likely to dampen the surging spirit of the market. Market insights suggests that the overall width of the global guerbet alcohols market will expand within the forecast period. Several positive changes are expected to fuel the growth of the market. The market is fragmented and each portion of the fragment has a crucial role to play in the market. In the product division, the 2-octyldodecanol will play a pivotal role in building the market revenue. This product type is expected to occupy a major share of the market. The report hints that the 2-octyldodecanol product type will account for a value share of almost 33.5% in the global guerbet alcohols market. The segment will surge at a CAGR of 6.7% within the forecast period. From the long queue of end users the personal & cosmetic care segment will mint a significant revenue within the forecast period. The steady expansion of the cosmetic market will affect the production of guerbet alcohol chemicals. As per the forecast this segment to account for more than 52% of the market value share by the end of the forecast period. Amongst the major markets Europe will show promising results within the forecast period. The region is estimated to represent more than 26% in 2016 and the market will expand at a CAGR of 5.1% within the stipulated time period. The sales revenue of the North American region will pump up to US$ 372.2 Mn by the end of 2024 with an increasing CAGR of 5.3%. The markets in the Asia Pacific region will remain fertile and vibrant during the forecast period. Some of the key market players who have been picked in the global guerbet alcohols market report are Sasol Ltd, BASF SE, New Japan Chemical Co., Ltd, Kisco Ltd., Kokyu Alcohol Kogyo Co., Ltd, DowPol Corporation. Persistence Market Research (PMR) is a third-platform research firm. Our research model is a unique collaboration of data analytics and market research methodology to help businesses achieve optimal performance. To support companies in overcoming complex business challenges, we follow a multi-disciplinary approach. At PMR, we unite various data streams from multi-dimensional sources. By deploying real-time data collection, big data, and customer experience analytics, we deliver business intelligence for organizations of all sizes.
Kisco Ltd., University of Tokyo and Daisankasei Co. | Date: 2012-06-22
Provided is: a cell culture membrane, which is free from materials derived from living organisms, can easily be industrially mass-produced, exhibits superior long-term storage properties and chemical resistance, has excellent cell adhesion properties and long-term culture properties and is capable of replicating a cell adhesion morphology that is similar to that of collagen derived from living organisms and being used for conventional cell cultivation. Also provided are a cell culture substrate, and a method for manufacturing the cell culture substrate. In the present invention, as a cell adhesion layer, a polymer membrane represented by formula (I) is formed on the base of a cell culture substrate so as to have a membrane thickness equal to or greater than 0.2 m (in the formula, R1 and R2 represent a (CH_(2))_(n)NH_(2 )moiety (n is an integer of 1-10 inclusive.) or H, with at least one of R1 and R2 being a (CH_(2))_(n)NH_(2 )moiety. Moreover, l and m are positive integers expressing polymerization degree).
Kisco Ltd., Daisankasei Co. and University of Tokyo | Date: 2014-04-30
Provided is: a cell culture membrane, which is free from materials derived from living organisms, can easily be industrially mass-produced, exhibits superior long-term storage properties and chemical resistance, has excellent cell adhesion properties and long-term culture properties and is capable of replicating a cell adhesion morphology that is similar to that of collagen derived from living organisms and being used for conventional cell cultivation. Also provided are a cell culture substrate, and a method for manufacturing the cell culture substrate. In the present invention, as a cell adhesion layer, a polymer membrane represented by formula (I) is formed on the base of a cell culture substrate so as to have a membrane thickness equal to or greater than 0.2 m (in the formula, R1 and R2 represent a -(CH_(2))_(n)-NH_(2) moiety (n is an integer of 1-10 inclusive.) or H, with at least one of R1 and R2 being a -(CH_(2))_(n)-NH_(2) moiety. Moreover, 1 and m are positive integers expressing polymerization degree).