Zlotnik A.,University of California at Irvine |
Yoshie O.,Kinki University
Immunity | Year: 2012
The chemokine superfamily consists of a large number of ligands and receptors. At first glance, this family appears redundant and their ligand-receptor relationships promiscuous, making its study challenging. However, analyzing this family from the evolutionary perspective greatly simplifies understanding both the organization and function of this apparently complex system. In particular, the functions of a subgroup of chemokines (designated homeostatic chemokines) have played pivotal roles in advancing our understanding of the organization and function of the cellular networks that shape the immune system. Here, we update the full scope of the human and mouse chemokine superfamilies and their relationships and summarize several important roles that homeostatic chemokines play in the immune system. © 2012 Elsevier Inc. Source
Asahi Kasei Corporation and Kinki University | Date: 2013-05-17
A medicament effective for prophylactic and/or therapeutic treatment of a peripheral neuropathic pain such as allodynia caused by a treatment with an anticancer agent, which comprises thrombomodulin as an active ingredient.
Kinki University and Link Genomics Inc. | Date: 2014-12-05
The present invention provides a prophylactic or therapeutic agent for various malignant tumors, including currently intractable solid tumors, which contains a novel antibody having the ability to bind to human LAT1/CD98 and inducing antibody-dependent cellular cytotoxicity specifically against cancer cells as an active ingredient.
Sofsera Corporation and Kinki University | Date: 2014-04-03
Silver particles are prepared by aggregating silver ions in accordance with a method including steps of (a), in preparing a mixed solution by adding a thiol compound to a solution containing silver ions, adjusting an amount of the thiol compound added to the solution and (b) adding a reducing agent to the mixed solution. This allows a particle size and antibacterial activity of the silver particles to be easily adjusted.
Kinki University and Euglena Co. | Date: 2014-02-28
The present invention provides a method for introducing a gene into