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Nagoya-shi, Japan

Kinjo Gakuin University is a private women's college in Moriyama-ku, Nagoya, Aichi Prefecture, Japan. The predecessor of the school was founded in 1889, and it was chartered as a university 1949. Wikipedia.

Tanaka T.,The Tohkai Cytopathology Institute Cancer Research and Prevention | Tanaka T.,Kanazawa Medical University | Tanaka T.,Kansai University of Health Sciences | Tanaka M.,Kinjo Gakuin University
Journal of Experimental and Clinical Medicine | Year: 2011

A natural phenolic compound, protocatechuic acid (3,4-dihydroxybenzoic acid), is present in many edible and medicinal plants. Recent studies, including our animal experiments, indicate that this simple phenolic acid could be protective against the development of epithelial malignancy in different tissues and cardiovascular diseases as well. The mechanism of the action is mostly associated with antioxidant activity, including inhibition of generation as well as scavenging of free radicals and upregulating antioxidant enzymes. The influence on Phases I and II of the metabolism of certain carcinogens and, perhaps, direct blocking of specific binding sites of ultimate carcinogens with DNA molecule, thus preventing adduct formation that may result in mutations and neoplastic transformation, also account for its cancer protective action. However, other biological aspects of the chemopreventive activity of protocatechuic acid are not fully studied. They include influence on the activity of inducible isoenzyme of cyclooxygenase and nitric oxide synthase, cell cycle-regulating proteins, or inflammatory cytokines, which are involved in oncogenesis. In view of its reported biological properties and relative safety, protocatechuic acid is a potential cancer chemopreventive product. © 2011.

Urban social movements (USMs) and regulation have co-evolved in Japan to deal with homelessness, spatializaing their politics on the national and subnational scales. The author first theorizes these USM-regulation relationships as scale-oriented dialectics between two opposing forces-"commoning and othering"-both of which in my view are always internalized in today's "rebel cities" (Harvey 2012, Rebel Cities, Verso). Then, he analyzes two trajectories of USMs that attempted commoning-ie radical opening up of public goods/spaces within "zones of weakness" (Lefebvre)-against policing and workfare disciplines. The author detects "rescaling" dialectics in the case of Yokohama and "nationalizing" dialectics in the case of Tokyo. Lastly, through exploring and refreshing Engels's notion of the (petit-)bourgeois utopia, the author concludes that our commoning projects and imaginaries are constrained by capitalist urban form that spatially others the homeless; but truly revolutionary moments of commoning emerge whenever people-even temporarily-conquer the fetishism of the public/private binary embedded in this urban form. © 2014 Antipode Foundation Ltd.

Kataoka T.,Yokohama College of Pharmacy | Watanabebe S.,Kinjo Gakuin University
Heterocycles | Year: 2011

Alkynyl- and alkenylselenonium salts reacted with nucleophiles at the α- or β-carbon depending upon the nucleophiles. The α-attack caused the addition-elimination reaction i.e., the apparent substitution reaction and the β-attack (the conjugate addition) generated an ylide, which brought about the tandem reaction to form a variety of heterocyclic compounds. Some new reactions proceeded via the selenuranes formed by the attack of a nucleophile on the positively charged selenium atom. An interesting tandem Michael-aldol reaction of enones (ynones) bearing a chalcogenide or a thioamide was developed. The reactions of the 1-[2-(methylchalcogeno)phenyl]propenones gave α-(α-hydroxyalkyl)enones (Morita-Baylis-Hillman adducts) after a work-up with Et 3N. The reactions of the 3-cinnamoyl-1,3- oxazolidine-2-thiones with aldehydes gave tricyclic compounds with a bridgehead bound to four heteroatoms. The asymmetric reactions simultaneously induced four stereocenters, three of which are contiguous. Removal of the chiral auxiliary provided 1,3-diols bearing three consecutive stereocenters. © The Japan Institute of Heterocyclic Chemistry.

Tanaka T.,Tohkai Institute of Cytopathology | Tanaka T.,Gifu University | Tanaka T.,Kansai University of Health Sciences | Tanaka M.,Kinjo Gakuin University | Kuno T.,Gifu University
Journal of Biomedicine and Biotechnology | Year: 2012

β-Cryptoxanthin, a carotenoid, and hesperidin, a flavonoid, possess inhibitory effects on carcinogenesis in several tissues. We recently have prepared a pulp (CHRP) and citrus juices (MJ2 and MJ5) from a satsuma mandarin (Citrus unshiu Mar.) juice (MJ). They contain high amounts of β-cryptoxanthin and hesperidin. We have demonstrated that CHRP and/or MJs inhibit chemically induced rat colon, rat tongue, and mouse lung tumorigenesis. Gavage with CHRP resulted in an increase of activities of detoxifying enzymes in the liver, colon, and tongue rats'. CHRP and MJs were also able to suppress the expression of proinflammatory cytokines and inflammatory enzymes in the target tissues. This paper describes the findings of our in vivo preclinical experiments to develop a strategy for cancer chemoprevention of colon, tongue, and lung neoplasms by use of CHRP and MJs. © 2012 Takuji Tanaka et al.

Hayashi M.,Kinjo Gakuin University
Environment and Planning A | Year: 2014

After the 1970s the new urban poverty (NUP) ballooned in Japan and the US, and it evoked policy responses that produced new, rescaled regulatory spaces to contain the poor on the fringe of social rights and the capital circuit. The paper illuminates this process through the comparison of Japanese and US trajectories, both of which, evolving through economic crises, have established unique pathways. The author first constructs a theoretical framework based on Marxian, Polanyian, and Lefebvrean traditions. Then, he compares national-scale poverty regulation in Japan and the US from the 1950s through the 2000s. Lastly, the author examines how the countries' regulation of a major aspect of the NUP-homelessness-intensified multiscalar rescaling processes. The paper concludes that regulation of the NUP represents a significant instance of uneven spatial development of capitalism mediated by the state that requires synthetic research. © 2014 Pion and its Licensors.

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