King Adbulaziz University

Jeddah, Saudi Arabia

King Adbulaziz University

Jeddah, Saudi Arabia
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Dooley J.,University of Essex | Henson M.,University of Essex | Callaghan V.,University of Essex | Hagras H.,University of Essex | And 4 more authors.
Proceedings - 2011 7th International Conference on Intelligent Environments, IE 2011 | Year: 2011

Ubiquitous Computing asserts that technology will soon be pervasive in our lives. But how will that technology be organized and made available to us as we roam through the many spaces of our daily lives? How will we see and use that which we have a right to, and more importantly, how will a lack of access rights be enforced? These are questions that have been raised following previous research projects. They become more significant as the concept of intelligent environments scales-up beyond the boundaries of four walls. In this paper we propose a formal model that will form a roadmap for some of our upcoming research. This paper is a hypothetical work that explores some questions and poses some answers - Influenced by experimentation and with a view to further investigation. © 2011 IEEE.

Girgis A.S.,National Research Center of Egypt | Panda S.S.,University of Florida | Farag I.S.A.,National Research Center of Egypt | El-Shabiny A.M.,National Research Center of Egypt | And 8 more authors.
Organic and Biomolecular Chemistry | Year: 2015

QSAR study describes the anti-neoplastic spiro-alkaloids with relevant molecular descriptors using CODESSA III software. The dispiro[3H-indole-3,2′-pyrrolidine-3′,3″-piperidines] 24-48 were synthesized via [3 + 2]-cycloaddition reaction of azomethine ylides, (generated in situ via decarboxylative condensation of isatins 21-23 with sarcosine) and 3E,5E-1-alkyl-3,5-bis(arylmethylidene)-4-piperidones 10-20. Some of the synthesized analogues exhibited promising antitumor properties against HELA (cervical), HEPG2 (liver), T-47D, MCF7 (breast), and HCT116 (colon) human tumor cell lines, demonstrating activity close to or even better than the standard Doxorubicin, based on in vitro Sulfo-Rhodamine-B bio-assay. © The Royal Society of Chemistry 2015.

Jones R.A.,University of Florida | Thillier Y.,University of Florida | Panda S.S.,University of Florida | Rivera Rosario N.,University of Florida | And 3 more authors.
Organic and Biomolecular Chemistry | Year: 2014

Strategies to couple non-steroidal anti-inflammatory drugs (NSAIDs) to a glucosamine hydrochloride salt via an amino acid linker are investigated and a series of novel NSAID-glucosamine bioconjugates have been prepared. This journal is © the Partner Organisations 2014.

Ifeduba E.A.,University of Georgia | Awachie M.N.,University of Georgia | Sabir J.S.M.,King Adbulaziz University | Akoh C.C.,University of Georgia | Akoh C.C.,King Adbulaziz University
JAOCS, Journal of the American Oil Chemists' Society | Year: 2013

Lipid compositions of two non-conventional oilseeds (Irvingia gabonensis and Treculia africana) were studied. Total lipids were extracted by the Folch method and phospholipids were isolated by solid phase extraction. Fatty acid compositions of total lipids and phospholipids were determined by gas chromatography. Phospholipid classes and tocopherols were quantified by HPLC. The major fatty acids in I. gabonensis seed total lipids were myristic (41.4-48.9 %) and lauric (39.8-46.8 %) while those in T. africana seed were linoleic (29.1-31.4 %) and oleic (22.9-25.9 %). The principal fatty acid at the sn-2 position of I. gabonensis seed triacylglycerols was myristic (49.5 %) while that of T. africana was linoleic (50.6 %). Phospholipid content of crude T. africana seed oil was 3.3 % and that of I. gabonensis was 0.1-0.3 %. The composition and distribution of saturated fatty acids in I. gabonensis seed lipids suggest that it may contribute to cardiovascular disease risk factors among the Igbo people in Nigeria that use the seed as food ingredient. © 2013 AOCS.

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