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Gobel A.,Kiel Migraine and Headache Center | Gobel A.,University of Lubeck | Gobel C.H.,Kiel Migraine and Headache Center | Gobel C.H.,Julich Research Center | And 2 more authors.
Cephalalgia | Year: 2014

Conclusions: Richard Wagner's life and opus can help to better understand the burden and suffering caused by migraine with its severe effects on the individual, familial and social life, the culture and community.Background: The headache phenotype and neurological symptoms of the German composer Richard Wagner (1813-1883), whose music dramas count towards the most frequently performed operas across the world, are previously undocumented.Methods: Richard Wagner's own descriptions of his headache symptoms in his original writings and letters are investigated, as well as the complete diary records of his second wife, Cosima Wagner.Results: There are manifold indications that Richard Wagner suffered from a severe headache disorder, which fulfils most likely the diagnostic criteria of migraine without aura and migraine with aura of ICHD-3 beta. © 2014 International Headache Society. Source


Gobel A.,Kiel Migraine and Headache Center | Gobel A.,University of Lubeck | Gobel C.H.,Kiel Migraine and Headache Center | Gobel C.H.,Julich Research Center | And 10 more authors.
Brain Stimulation | Year: 2015

Background: Within the last years, occipital nerve stimulation (ONS) has proven to be an important method in the treatment of severe therapy-resistant neurological pain disorders. The correspondence between lead placement as well as possible stimulation parameters and the resulting stimulation effects remains unclear. Objective: The method aims to directly relate the neuromodulatory mechanisms with the clinical treatment results, to achieve insight in the mode of action of neuromodulation, to identify the most effective stimulation sets and to optimize individual treatment effects. Methods: We describe a new computer-based imaging method for mapping the spatial, cognitive and affective sensory effects of ONS. The procedure allows a quantitative and qualitative analysis of the relationship between lead positioning, the stimulation settings as well as the sensory and clinical stimulation effects. Conclusion: A regular mapping of stimulation and sensory parameters allows a coordinated monitoring. The stimulation results can be reviewed and compared with regards to clinical effectiveness. © 2015 Elsevier Inc. All rights reserved. Source

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