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Dutova S.V.,tanov Khakassian State University | Karpova M.R.,Siberian State Medical University | Myadelets M.A.,Russian Academy of Sciences | Myasnaya N.V.,Russian Academy of Medical Sciences | Sherstoboev E.Yu.,Russian Academy of Medical Sciences
Eksperimental'naya i Klinicheskaya Farmakologiya | Year: 2015

A preclinical study of the immunocorrection action of the sum of active substances isolated from ethereal-oil plants Collina geoides (Pall.) Ledeb. (Rosaceae family) with respect to experimental immunodeficiency showed that preparations relieve symptoms of immunodeficiency caused by the administration of cyc-lophosphan: suppressed synthesis of anti-erythrocyte antibodies (agglutinine) and proliferative processes in the spleen. Under the influence of C. geoides preparations, the absolute numbers of cariocytes and antibody forming cells in spleen significantly increased (compared to the group of animals with experimental immunodeficiency) and in some cases reached the background level. The drugs studied produced a more pronounced stimulating effect on the synthesis of specific immunoglobulins and proliferation of antibody forming cells of spleen as compared to the effect of Echinacea tincture. Preparation C-2 (extract from underground organs and grass of C. geoides obtained by percolation method with 70% ethanol) is most promising for in-depth research and the development of new effective drugs with immunocorrecting properties.

Zauzolkova N.A.,tanov Khakassian State University | Gorbunova I.A.,Russian Academy of Sciences
Mikologiya I Fitopatologiya | Year: 2016

The paper discusses a biota of agaricoid and gasteroid basidiomycetes in steppe communities of the Minusinsk hollow (Khakassiya Republic, Krasnoyarsk Territory). Overall, 465 species of agaricoid and gasteroid macromycetes relating to 108 genera, 29 families and 6 orders have been revealed. A total of 288 new species has been recorded for the area of Minusinsk hollow, 199 species new to Khakassiya Republic. Among them are Suillus neoalbidipes, Conocybe macrospora and Hohenbuehelia mastrucata, that had not previously been encountered in Siberia. 32 species are listed as rare for the study area, 16 species - for the territory of Siberia. The paper presents annotated checklist of 114 species of agaricoid fungi and gasteromycetes previously unpublished for the Khakasiya Republic and Krasnoyarsk Territory near Minusinsk hollow.

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