Lu C.-Z.,Lanzhou University |
Lu C.-Z.,Gansu Nephro Urological Clinical Center |
Lu C.-Z.,Key Laboratory of Urological Diseases of in Gansu Province |
Xiao E.-L.,Lanzhou University |
And 5 more authors.
Chinese Journal of Evidence-Based Medicine
Objective To systematically review the effectiveness and safety of laparoendoscopic single-site surgery (LESS) for varicocele. Methods Such databases as The Cochrane Library, MEDLINE, EMbase, CBM, CNKI, and WanFang Data were electronically searched for studies about LESS and traditional laparoscopy for varicocele till March 1st, 2013. According to the inclusion and exclusion criteria, literature was screened, data were extracted, and the methodological quality of included studies was also assessed. Then, meta-analysis was performed using RevMan 5.1 software. Results Seven RCTs involving 452 cases were included. The results of meta-analysis showed that, there was no significant difference between LESS and traditional laparoscopy for varicocele on post-operational complications (RR=0.57, 95%CI 0.26 to 1.27, P=0.17), duration of hospital stay (MD=-0.30, 95%CI -0.87 to 0.26, P=0.30), improvement of semen parameters, and blood loss. However, LESS had longer duration of operation (MD=11.26, 95%CI 3.62 to 18.90, P=0.004). Conclusion The effectiveness and safety of LESS and traditional laparoscopy for varicocele are similar, and LESS could achieve more beautiful and natural effects which has longer surgery time on account of non-proficiency in surgery and equipment. Due to the limited quantity and quality of the included studies, the above conclusion requires to be proved by more high quality randomized controlled trials. © 2014 Editorial Board of Chin J Evid-based Med. Source