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Shen S.G.,Hebei University | Shen S.G.,Key Laboratory of Medical Chemistry and Molecular Diagnosis | Xia L.Y.,Hebei University | Xia L.Y.,Key Laboratory of Medical Chemistry and Molecular Diagnosis | And 2 more authors.
Advanced Materials Research | Year: 2013

To distinguish the geographic origin of rice, high performance liquid chromatogram of the ethyl acetate extracts of rice was analyzed by principal component analysis (PCA) and linear discriminant analysis (LDA). Total of 23 characteristic peaks which closely related to the origin information were determined by stepwise LDA and PCA. Among these characteristic peaks, the peaks at 22.06min, 38.00 min, 40.66 min, 35.93 min, 17.87 min and 5.39min played even more significant roles. The discrimination accuracies and cross-validation obtained by LDA achieved 100.0% and 97.7%, respectively. The results indicated that the proposed method could be efficiently used to control the quality of Xiangshui rice and providing a reference method for chemical pattern recognition for other geography sign product. © (2013) Trans Tech Publications, Switzerland.


Zhang H.,Hebei University | Zhang H.,Key Laboratory of Medical Chemistry and Molecular Diagnosis | Zhu X.,Hebei University | Zhu X.,Key Laboratory of Medical Chemistry and Molecular Diagnosis | And 6 more authors.
Journal of Materials Science | Year: 2015

New hybrid halloysite nanotubes (HNTs) were obtained by grafting conjugated polyfluorenes (PFs) onto the surface via “click” chemistry. The hybrid material can be dispersed in organic solvent such as dichloromethane, and exhibits intense blue emission peaked at 448 nm. The absorption and emission spectra of the HNTs show distinct bathochromic shifts compared to PFs, which can be attributed to the extended π-conjugation as a result of the cycloaddition of azide and alkyne groups. The changes of the spectra also show that the PFs were grafted onto the HNTs through chemical bonds. Thermal gravimetric analyzer data show one more significant result, the grafting degree of the HNTs is 150 %, which means that a high mass ratio of PF polymers was grafted onto the HNTs. Furthermore, characterizations by infrared, nuclear magnetic resonance, and X-ray photoelectron spectroscopy also support the conclusion. The combination of HNTs with conjugated polymers will lead to a new generation of donor–acceptor nanohybrid materials which are promising in application in photoelectric fields. © 2015, Springer Science+Business Media New York.


Wu Y.,Hebei University | Hao X.,Hebei University | Wu J.,Hebei University | Jin J.,Hebei University | And 2 more authors.
Macromolecules | Year: 2010

A series of novel hyperbranched ladder-type poly(p-phenylene)s containing truxene units have been prepared through the Pd(0)-catalyzed Suzuki polymerization with an "A2 + B3" or "A 2 + B2+ B3" approach. The polymers with different linear length show pure blue light emission from 417 to 465 nm. All the ladder-type polymers exhibit well-resolved absorption and emission spectra and small Stokes shifts in both solutions and thin films, which are the characteristics of full ladder-type poly(p-phenylene)s. The threedimensional structures make the materials soluble in common organic solvents and able to form quality amorphous films, leading to polymer light-emitting diodes (PLEDs) with improved stability and efficiency. © 2009 American Chemical Society.


Bai L.,Hebei University | Bai L.,Key Laboratory of Analytical Science and Technology of Hebei Province | Li W.,Hebei University | Chen J.,Hebei University | And 13 more authors.
Macromolecular Rapid Communications | Year: 2013

Novel water-soluble dendronized fluorescent polyfluorenes (DFPFs) are prepared from hydrophilic monomers and hydrophobic comonomers. Incomplete energy transfer is found to result in a two-color emission of the DFPFs at around 410 and 650 nm. The incomplete energy transfer can be attributed to the poor compatibility between the fluorene and benzothiadiazole units. Polyethylene oxide (PEO) encapsulation of the DFPFs shows over 90% cell viability, indicating good biocompatibility. These DFPFs show differential cellular uptake. P1 with fewer PEO chains exhibits limited cellular membrane uptake and low brightness in cells. By contrast, P3 with more PEO chains is efficiently internalized by cells and accumulated in the cytoplasm. A strong fluorescence from whole cells is also observed. New water-soluble dendronized fluorescent polyfluorenes are designed. These polyfluorenes show two-color emission, good cytocompatibility, and differential cellular uptake. P1 shows limited cellular uptake and low brightness in cells. By contrast, P3 is efficiently internalized by cells and accumulated in the cytoplasm. A strong fluorescence from whole cells is also observed. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Song Y.-L.,Hebei University | Song Y.-L.,Key Laboratory of Medical Chemistry and Molecular Diagnosis | Dong Y.-F.,Hebei University | Dong Y.-F.,Key Laboratory of Medical Chemistry and Molecular Diagnosis | And 13 more authors.
Bioorganic and Medicinal Chemistry | Year: 2013

In an effort to develop potent anti-cancer chemopreventive agents that act on topoisomerase II, a novel series of bisindolylalkanes analogues such as 3,3′-(thiochroman-4,4-diyl)bis(1H-indole) are synthesized. Structures of all compounds are elucidated by 1H NMR, 13C NMR and HRMS. Anti-proliferative activities for all of these compounds are investigated by the method of MTT assay on 7 human cancer lines. Most of them showed antitumor activities in vitro, the half maximal inhibitory concentration (IC50) value is 7.798 μg/mL of 3a against MCF7. Compound 3a showed comparable topoisomerase II inhibitory activity to etoposide (VP-16) at 100 μM concentration. The rest of the compounds also showed varying degree topoisomerase II inhibitory activity. © 2013 Elsevier Ltd. All rights reserved.


Chang P.,Hebei University | Wang Y.,Hebei University | Wang Y.,Agricultural University of Hebei | Gu F.,Hebei University | And 2 more authors.
Gaodeng Xuexiao Huaxue Xuebao/Chemical Journal of Chinese Universities | Year: 2015

The effect of cyclization on the average properties of hyperbranched polymers formed in the polymerization system of ABg type was investigated by the method of Monte Carlo simulation. In the system of interest with cyclization, a set of differential kinetic equations based on the generation growth of polymers was given. The simulation is then performed by using the intermolecular and intramolecular reaction rates deduced from the principle of statistical mechanics. Specifically, the number of treelike and cyclic polymers, the number of loops, size distribution, the number-and weight-average molecular weights were given. Furthermore, the effect of cyclization on the average properties of polymers was discussed. It is shown that the volume fraction of monomers plays an important role in cyclization, which determines whether the influence of solvent quality and functionality is significant or not. As a result, the cyclization depends in essence on the cooperation of the above three factors. It is expected that the present study is helpful to design the related materials. ©, 2015, Higher Education Press. All right reserved.


Xu X.,Key Laboratory of Analytical Science and Technology of Hebei Province | Li J.,Key Laboratory of Medical Chemistry and Molecular Diagnosis | Li J.,Key Laboratory of Analytical Science and Technology of Hebei Province | Li J.,Hebei University | And 2 more authors.
Chinese Journal of Chemistry | Year: 2011

Synthesis of 1,3-diaryl-2-propen-1-one oxime via the condensation of 1,3-diaryl-2-propen-1-one with hydroxylamine hydrochloride in the presence of anhydrous sodium sulfate was carried out in refluxing EtOH for 2-4 h in 83%-93% yields. The significant features of the present procedure include higher yield, shorter reaction time, reduced molar ratio of hydroxylamine hydrochloride to substrate, compared to the reported literature method. Synthesis of 1,3-diaryl-2-propen-1-one oxime via the condensation of 1,3-diaryl-2-propen-1- one with hydroxylamine hydrochloride in the presence of anhydrous sodium sulfate was carried out in refluxing EtOH for 2-4 h in 83%-93% yields. The significant features of the present procedure include higher yield, shorter reaction time, the apparently reduced molar ratio of hydroxylamine hydrochloride to substrate as compared to the reported literature method. © 2011 SIOC, CAS, Shanghai, & WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Liu X.-Y.,Hebei University | Li J.-T.,Hebei University | Gu F.,Hebei University | Wang H.-J.,Hebei University | Wang H.-J.,Key Laboratory of Medical Chemistry and Molecular Diagnosis
Chinese Journal of Chemical Physics | Year: 2015

Phase equilibria of hydrogen bonding (HB) fluid confined in a slit pore with broken symmetry were investigated by the density functional theory incorporated with modified fundamental measure theory, where the symmetry breaking originated from the distinct interactions between fluid molecules and two walls of the slit pore. In terms of adsorption-desorption isotherms and the corresponding grand potentials, phase diagrams of HB fluid under various conditions are presented. Furthermore, through phase coexistences of laying transition and capillary condensation, the effects of HB interaction, pore width, fluid-pore interaction and the broken symmetry on the phase equilibrium properties are addressed. It is shown that these factors can give rise to apparent influences on the phase equilibria of confined HB fluid because of the competition between intermolecular interaction and fluid-pore interaction. Interestingly, a significant influence of broken symmetry of the slit pore is found, and thus the symmetry breaking can provide a new way to regulate the phase behavior of various confined fluids. © 2015 Chinese Physical Society.


Gu F.,Hebei University | Wang H.,Hebei University | Wang H.,Key Laboratory of Medical Chemistry and Molecular Diagnosis | Wang H.,CAS International Center for Materials Physics | Fu D.,North China Electrical Power University
Acta Chimica Sinica | Year: 2011

The depletion potential between two colloid particles immersed in a Lennard-Jones fluid is investigated by the density functional theory for depletion potential proposed by Roth, Evans and Dietrich. An attempt is made to study the effects of several factors concerning colloid particles and solvent molecules on the depletion potential, which are the volume fraction of solvent, the size ratio of colloid particle to solvent, the interaction between solvent molecules, and the interaction between colloid particle and solvent. By means of the depletion potential presented under various conditions, it is shown that the effects of these factors on the depletion potential are significant, and this can provide some useful clues on regulating the interaction between colloid particles in the related experiments.


Kong W.-Y.,Hebei University | Wang H.-J.,Hebei University | Wang H.-J.,Key Laboratory of Medical Chemistry and Molecular Diagnosis | Wang H.-J.,CAS International Center for Materials Physics | Gu F.,Hebei University
Wuli Huaxue Xuebao/ Acta Physico - Chimica Sinica | Year: 2011

The depletion potential between two colloid particles immersed in a hard-core Yukawa fluidwas investigated by density functional theory for the depletion potential proposed by Roth, Evans, andDietrich. An attempt was made to study the effects of several factors concerning the colloid particles andthe solvent molecules on the depletion potential, which are the size ratio of the colloid particle to thesolvent, the interaction between solvent molecules, the packing fraction of the solvent, and the interactionbetween the colloid particle and the solvent. By means of the depletion potential presented under variousconditions, it is shown that the effects of these factors on the depletion potential are significant and this canprovide some useful clues on regulating the interaction between colloid particles in related experiments. © Editorial office of Acta Physico-Chimica Sinica.

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