Entity

Time filter

Source Type


Gu F.,Hebei University | Wang H.,Hebei University | Wang H.,Key Laboratory of Medical Chemistry and Molecular Diagnosis | Wang H.,CAS International Center for Materials Physics | Fu D.,North China Electrical Power University
Acta Chimica Sinica | Year: 2011

The depletion potential between two colloid particles immersed in a Lennard-Jones fluid is investigated by the density functional theory for depletion potential proposed by Roth, Evans and Dietrich. An attempt is made to study the effects of several factors concerning colloid particles and solvent molecules on the depletion potential, which are the volume fraction of solvent, the size ratio of colloid particle to solvent, the interaction between solvent molecules, and the interaction between colloid particle and solvent. By means of the depletion potential presented under various conditions, it is shown that the effects of these factors on the depletion potential are significant, and this can provide some useful clues on regulating the interaction between colloid particles in the related experiments. Source


Kong W.-Y.,Hebei University | Wang H.-J.,Hebei University | Wang H.-J.,Key Laboratory of Medical Chemistry and Molecular Diagnosis | Wang H.-J.,CAS International Center for Materials Physics | Gu F.,Hebei University
Wuli Huaxue Xuebao/ Acta Physico - Chimica Sinica | Year: 2011

The depletion potential between two colloid particles immersed in a hard-core Yukawa fluidwas investigated by density functional theory for the depletion potential proposed by Roth, Evans, andDietrich. An attempt was made to study the effects of several factors concerning the colloid particles andthe solvent molecules on the depletion potential, which are the size ratio of the colloid particle to thesolvent, the interaction between solvent molecules, the packing fraction of the solvent, and the interactionbetween the colloid particle and the solvent. By means of the depletion potential presented under variousconditions, it is shown that the effects of these factors on the depletion potential are significant and this canprovide some useful clues on regulating the interaction between colloid particles in related experiments. © Editorial office of Acta Physico-Chimica Sinica. Source


Chang P.,Hebei University | Wang Y.,Hebei University | Wang Y.,Agricultural University of Hebei | Gu F.,Hebei University | And 2 more authors.
Gaodeng Xuexiao Huaxue Xuebao/Chemical Journal of Chinese Universities | Year: 2015

The effect of cyclization on the average properties of hyperbranched polymers formed in the polymerization system of ABg type was investigated by the method of Monte Carlo simulation. In the system of interest with cyclization, a set of differential kinetic equations based on the generation growth of polymers was given. The simulation is then performed by using the intermolecular and intramolecular reaction rates deduced from the principle of statistical mechanics. Specifically, the number of treelike and cyclic polymers, the number of loops, size distribution, the number-and weight-average molecular weights were given. Furthermore, the effect of cyclization on the average properties of polymers was discussed. It is shown that the volume fraction of monomers plays an important role in cyclization, which determines whether the influence of solvent quality and functionality is significant or not. As a result, the cyclization depends in essence on the cooperation of the above three factors. It is expected that the present study is helpful to design the related materials. ©, 2015, Higher Education Press. All right reserved. Source


Song Y.-L.,Hebei University | Song Y.-L.,Key Laboratory of Medical Chemistry and Molecular Diagnosis | Dong Y.-F.,Hebei University | Dong Y.-F.,Key Laboratory of Medical Chemistry and Molecular Diagnosis | And 13 more authors.
Bioorganic and Medicinal Chemistry | Year: 2013

In an effort to develop potent anti-cancer chemopreventive agents that act on topoisomerase II, a novel series of bisindolylalkanes analogues such as 3,3′-(thiochroman-4,4-diyl)bis(1H-indole) are synthesized. Structures of all compounds are elucidated by 1H NMR, 13C NMR and HRMS. Anti-proliferative activities for all of these compounds are investigated by the method of MTT assay on 7 human cancer lines. Most of them showed antitumor activities in vitro, the half maximal inhibitory concentration (IC50) value is 7.798 μg/mL of 3a against MCF7. Compound 3a showed comparable topoisomerase II inhibitory activity to etoposide (VP-16) at 100 μM concentration. The rest of the compounds also showed varying degree topoisomerase II inhibitory activity. © 2013 Elsevier Ltd. All rights reserved. Source


Xu X.,Key Laboratory of Analytical Science and Technology of Hebei Province | Li J.,Key Laboratory of Medical Chemistry and Molecular Diagnosis | Li J.,Key Laboratory of Analytical Science and Technology of Hebei Province | Li J.,Hebei University | And 2 more authors.
Chinese Journal of Chemistry | Year: 2011

Synthesis of 1,3-diaryl-2-propen-1-one oxime via the condensation of 1,3-diaryl-2-propen-1-one with hydroxylamine hydrochloride in the presence of anhydrous sodium sulfate was carried out in refluxing EtOH for 2-4 h in 83%-93% yields. The significant features of the present procedure include higher yield, shorter reaction time, reduced molar ratio of hydroxylamine hydrochloride to substrate, compared to the reported literature method. Synthesis of 1,3-diaryl-2-propen-1-one oxime via the condensation of 1,3-diaryl-2-propen-1- one with hydroxylamine hydrochloride in the presence of anhydrous sodium sulfate was carried out in refluxing EtOH for 2-4 h in 83%-93% yields. The significant features of the present procedure include higher yield, shorter reaction time, the apparently reduced molar ratio of hydroxylamine hydrochloride to substrate as compared to the reported literature method. © 2011 SIOC, CAS, Shanghai, & WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Source

Discover hidden collaborations