Gao L.,Liaoning Ocean and Fisheries Science Research Institute |
Gao L.,Key Laboratory of Marine Fishery Molecular Biology of Liaoning Province |
He C.,Liaoning Ocean and Fisheries Science Research Institute |
He C.,Key Laboratory of Marine Fishery Molecular Biology of Liaoning Province |
And 8 more authors.
International Journal of Molecular Sciences | Year: 2012
Catfish is one of the most important aquaculture species in America (as well as in Asia and Africa). In recent years, the production of catfish has suffered massive financial losses due to pathogen spread and breakouts. Innate immunity plays a crucial role in increasing resistance to pathogenic organisms and has generated increasing interest in the past few years. This review summarizes the current understanding of innate immune-related genes in catfish, including pattern recognition receptors, antimicrobial peptides, complements, lectins, cytokines, transferrin and gene expression profiling using microarrays and next generation sequencing technologies. This review will benefit the understanding of innate immune system in catfish and further efforts in studying the innate immune-related genes in fish. © 2012 by the authors; licensee MDPI, Basel, Switzerland.