Key Laboratory of Geriatrics

Key Laboratory of Geriatrics

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Gao X.,Key Laboratory Of Geriatrics Email | Bao L.,Key Laboratory of Geriatrics | Yu H.,Beijing Hospital and Beijing Institute of Geriatrics | Qin B.,Beijing Hospital and Beijing Institute of Geriatrics | And 2 more authors.
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi | Year: 2014

OBJECTIVE: To study the effects of type 2 diabetes (T2DM) with hypertension on cognitive function in those community-based elderly who were aged 60 and over, in Beijing.METHODS: 82 patients with T2DM, 142 patients with both T2DM and hypertension and 277 normal controls were investigated in this study. Both methods as: the Montreal Cognitive Assessment (MoCA) and Mini-Mental Status Examination (MMSE)were used to determine cognitive change.RESULTS: The total MMSE scores showed significant decrease between T2DM with hypertension and controls [(28.42 ± 1.52) vs. (28.88 ± 1.47), P < 0.05]. The MoCA score of the total scores [(25.20 ± 3.91) vs. (26.50 ± 3.29), P < 0.05], sub-scores of visuospatial, executive [(3.60 ± 1.56) vs. (3.96 ± 1.18), P < 0.05] and language [(2.10 ± 0.80) vs. (2.37 ± 0.80), P < 0.05] significantly decreased in T2DM patients with hypertension and in the normal controls. Data from the Multiple logistic regression analysis showed that older age and less education were risk factors for cognitive impairment.CONCLUSION: T2DM and hypertension damaged the cognitive function of patients.


PubMed | Key Laboratory of Geriatrics, Beijing Hospital and Beijing Institute of Geriatrics and Key Laboratory Of Geriatrics Email
Type: Journal Article | Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi | Year: 2014

To study the effects of type 2 diabetes (T2DM) with hypertension on cognitive function in those community-based elderly who were aged 60 and over, in Beijing.82 patients with T2DM, 142 patients with both T2DM and hypertension and 277 normal controls were investigated in this study. Both methods as: the Montreal Cognitive Assessment (MoCA) and Mini-Mental Status Examination (MMSE)were used to determine cognitive change.The total MMSE scores showed significant decrease between T2DM with hypertension and controls [(28.42 1.52) vs. (28.88 1.47), P < 0.05]. The MoCA score of the total scores [(25.20 3.91) vs. (26.50 3.29), P < 0.05], sub-scores of visuospatial, executive [(3.60 1.56) vs. (3.96 1.18), P < 0.05] and language [(2.10 0.80) vs. (2.37 0.80), P < 0.05] significantly decreased in T2DM patients with hypertension and in the normal controls. Data from the Multiple logistic regression analysis showed that older age and less education were risk factors for cognitive impairment.T2DM and hypertension damaged the cognitive function of patients.

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