Ding Q.,Jiangxi Normal University |
Ding Q.,Key Laboratory of Functional Small Organic Molecule |
Liu X.,Jiangxi Normal University |
Cao B.,Jiangxi Normal University |
And 3 more authors.
Tetrahedron Letters | Year: 2011
A CuCl 2·H 2O-catalyzed tandem reaction of 2-iodophenol with isothiocyanate in water is described, which provides an environmentally benign, efficient, and practical route for the generation of 2-iminobenzo-1,3-oxathiole. It was noteworthy that most of the products were easily separated from the reaction system by simple filtration. © 2011 Elsevier Ltd. All rights reserved.
Shang X.,Jiangxi Normal University |
Shang X.,Key Laboratory of Functional Small Organic Molecule |
Zhou X.,Jiangxi Normal University |
Zhou X.,Key Laboratory of Functional Small Organic Molecule |
And 5 more authors.
Tetrahedron | Year: 2015
Tosylhydrazine mediated conjugate reduction of 2-hydroxyl chalcones and sequential reductive coupling cyclization is described. This is an unprecedented protocol and an extremely efficient method for a one-pot domino synthesis of 2-arylchromans in good to excellent yields from commercially available, cheap starting materials. More importantly, the two-step reactions can be easily controlled to afford dihydrochalcones or 2-arylchromans by the mole amounts of tosylhydrazine. Furthermore, the operational simplicity of the process and the high functional group tolerance are remarkable. © 2015 Elsevier Ltd. All rights reserved.