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Kermānshāh, Iran

Shahriari S.,Kermanshah University of Medical Sciences | Khanahmadi M.,Kermanshah Branch of ACECR | Tahvilian R.,Kermanshah University of Medical Sciences
Journal of Reports in Pharmaceutical Sciences | Year: 2013

The genus Hymenocrater, belong to the Lamiaceae family, consist of 21 species throughout the world. In Iran, about 9 species are present, of which some are endemic. Plants belonging to these genuses are pharmacologically active and have been used in folk medicine all around the world. The aim of the present study was to detect the essential oils composition of Hymenocrater longiflorus Benth. collected from Paveh, Kermanshah province. Plant sample was dried in shade condition and the essential oil of the plant obtained by hydrodistillation by Clevenger type apparatus was analyzed by GC/MS. Yield of essential oil was (1.5% v/w). The major components of the oil of H. longiflorus Benth were Hedycaryol (22.2), α- Cadinol (20.43), β-Bourbonene (5.76%), α-Terpineol (4.95%), Eudesmol <7-Epi-> (4.84%), β-Bourbonene (4.69%), Caryophylene oxide (4.32%) and Geijerene (4.08%), Caryophelen (2.99), Sabinene (2.6%), 1,8-Cineole (2.58%), δ-Amorphene (2.58%), δ-Caddinene (2.24%) and α-Pinene (2.07%) were the main compounds with the greatest content. © 2013 by Kermanshah University of Medical Sciences. Source


Khanahmadi M.,Kermanshah Branch of ACECR | Rezazadeh S.H.,Institute of Medicinal Plants | Tara M.,Razi University
Asian Journal of Plant Sciences | Year: 2010

The aim of this study was to investigate antioxidant and antibacterial activities of ethanolic extract of Smyrnium cordifolium Boiss. the ethanolic extract was subjected to screening for its possible antioxidant activity. Namely DPPH free radical scavenging, FTC system and total phenolic compounds were used. Also, Antibacterial activity of ethanolic extract using Gentamicin and Tetracycline as the reference standards were tested against Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Klebsiella pneumoniae. The results revealed good antioxidant activity of the extract. The ethanolic extract of S. cordifolium exhibited an antibacterial activity at different levels against strains reported as the causal agents of diseases and this extract inhibited Gram positive bacteria significantly higher than Gram negative bacteria. Observed antioxidant and antibacterial properties of ethanolic extract of the S. cordifolium in this study showed that this plant might be useful source for the development of new and more potent natural antioxidants and antibacterial. © 2010 Asian Network for Scientific Information. Source


Khazaei M.,Kermanshah University of Medical Sciences | Montaseri A.,Kermanshah University of Medical Sciences | Khazaei M.R.,Kermanshah University of Medical Sciences | Khanahmadi M.,Kermanshah Branch of ACECR
International Journal of Fertility and Sterility | Year: 2011

Background: Foeniculum vulgare (FVE) is used in traditional medicine for its antiseptic, palliative and anti-inflammatory effects. Traditionally, FVE is utilized for treating female infertility. The present study aims to investigate the effects of FVE extract on folliculogenesis in female albino mice. Materials and Methods: In this experimental study, a total of 20 female albino mice were divided into four groups. Groups 1 and 2 (experimental) received FVE alcoholic extract at doses of 100 and 200 mg/kg body weight (BW)/day for five days. Group 3 (negative control) received ethanol and group 4 (positive control) was administered normal saline, in the same doses as the experimental groups. Animals in all groups were sacrificed on the sixth day of the study; their ovaries were dissected out and prepared for histological examinations. Hematoxylin and eosin (H&E) stained microscopic slides were evaluated and the numbers of ovarian follicles were compared between groups. Data were analyzed by one way ANOVA. Results: The total follicle numbers were 26.5 ± 5.24 for group 1 (100 mg/kg FVE), 27.2 ± 4.1 for group 2 (200 mg/kg FVE), 10.1 ± 2.53 for group 3 (ethanol control) and 17.2 ± 3.9 for the saline control group (group 4). The numbers of graffian, antral and multilaminar follicles increased significantly in both experimental groups when compared with the control groups (p<0.05), however there were no significant differences in follicle numbers among the experimental groups. The number of unilaminar primary follicles did not significantly change between all groups. GCMS analysis of FVE extract identified the presence of diosgenin, an estrogenic compound. Conclusion: FVE induced folliculogenesis in female mice ovary and increased the number of growing ovarian follicles. The estrogenic component of FVE, diosgenin, may exert this effect. Source


Daraei A.,Kermanshah Branch of ACECR
Iranian Journal of Chemistry and Chemical Engineering | Year: 2013

In this study a sample of bentonite obtained from Semnan mines, was modified by a surfactant to prepare an organoclay with high surface area. BET analysis showed that the modification increased its surface significantly. The prepared sorbent was used for removal of dyes and other organic pollutants from a waste water obtained from Ekbatan textile company. Adsorption was studied in various times to obtain the saturation time. pH variation has significant effect on adsorption and led to variation of adsorbed pollutant. At pH=4.5 the pollutant concentration became minimum which showed the pH is optimum pH for adsorption. Increasing the sorbent to waste solution ratio up to 1.2 g/L also increased the sorption. Adsorption isotherm was investigated for fitting with Langmuir isotherm and it has good fitness. Source


Taran M.,Razi University | Sharifi M.,Razi University | Azizi E.,Razi University | Khanahmadi M.,Kermanshah Branch of ACECR
Journal of Medicinal Plants | Year: 2010

Background: Pistacia khinjuk is one of the three species Pistacia growing in Iran. The essential oils of some Pistacia plants contain variety of components with different therapeutical effects. Objective: The purpose of this study was to provide the examination of antibacterial and antifungal effects of chloroform, ethyl acetate, ethyl alcohol and diethyl ether extracts obtained from the leaves of P. khinjuk. Method: for obtaining different extracts of P. khinjuk, 30 gr of leaves powder was macerated with 120 ml of each solvent (chloroform, ethyl acetate, ethyl alcohol, diethyl ether). The antibacterial and antifungal activities of different extracts was individually tested against a panel of microorganisms, including Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Klebsiella pneumoniae, Candida albicans and Saccharomyces cerevisiae Results: Some major constituents of essential oil from the aerial parts of P. khinjuk are α-pinene, β-pinene, Myrcene, beta-caryophyllene, Germacrene B and Spathulenol. The extracts showed antimicrobial activity against bacteria (MIC = 0.02-0.5 mg/ml) and fungi (MIC = 0.06-0.4 mg/ml). Conclusion: In conclusion the different leaves extracts of P.khinjuk (chloroform, ethyl acetate, ethyl alcohol, diethyl ether) like other species of Pistacia show antibacterial and antifungal activities. Source

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