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Watson, CA, United States

Keck Graduate Institute is a private graduate school in Claremont, California. Founded in 1997, it is the newest and 7th member of the Claremont Consortium. It offers 5 graduate degree programs in a range disciplines focusing in the life science industry. KGI programs are organized into two professional schools, the School of Applied Life Science and School of Pharmacy . KGI also offers a four-year undergraduate program, the Minerva Schools at KGI, in partnership with the Minerva Project. Wikipedia.

Niemz A.,Keck Graduate Institute of Applied Life Sciences | Ferguson T.M.,Claremont Biosolutions, Llc | Boyle D.S.,Program for Appropriate Technology in Health
Trends in Biotechnology | Year: 2011

Nucleic acid testing for infectious diseases at the point of care is beginning to enter clinical practice in developed and developing countries; especially for applications requiring fast turnaround times, and in settings where a centralized laboratory approach faces limitations. Current systems for clinical diagnostic applications are mainly PCR-based, can only be used in hospitals, and are still relatively complex and expensive. Integrating sample preparation with nucleic acid amplification and detection in a cost-effective, robust, and user-friendly format remains challenging. This review describes recent technical advances that might be able to address these limitations, with a focus on isothermal nucleic acid amplification methods. It briefly discusses selected applications related to the diagnosis and management of tuberculosis, HIV, and perinatal and nosocomial infections. © 2011.

Phillips M.I.,Keck Graduate Institute of Applied Life Sciences
Expert Opinion on Orphan Drugs | Year: 2013

For many years the highly profitable pharmaceutical companies had no interest in the rare disease community or its need for orphan product development. The collective rare disease market by definition was small. It did not offer the profits of drugs like antihypertensives with a market of more than 25 million patients. However, nothing stays the same. The blockbuster model that traditionally drove the pharmaceutical industry seems to have lost its relevance. "Big Pharma" has reached out for a new model and found that orphan drugs may be the answer. © Informa UK, Ltd.

Keck Graduate Institute of Applied Life Sciences | Date: 2013-04-10

A disposable and inexpensive biological diagnostic cartridge for the amplification and detection of nucleic acids includes a configuration having a reaction pouch for amplification which is compressed by a flexible pump pouch for detection of the amplified reaction.

Keck Graduate Institute of Applied Life Sciences | Date: 2013-04-09

A valve has a generally hollow core with one open end and one closed end, and at least one side port in a sidewall of the core. The valve also includes a sleeve that fits over the core and covers the side port(s). The cracking pressure of the valve is tunable by varying the parameters of the sleeve.

Keck Graduate Institute of Applied Life Sciences | Date: 2014-03-07

In accordance with the invention, isolated nucleic acids, expression methods, host cells, expression vectors, and DNA constructs for producing proteins, and proteins produced using the expression methods are described. More particularly, nucleic acids isolated from

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