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Abaci A.,Kecioren Egitim ve Arastirma Hastanesi | Bober E.,Dokuz Eylul University | Buyukgebiz A.,Cocuk Endokrinoloji Bolumu
Turkiye Klinikleri Pediatri | Year: 2010

Diabetic ketoacidosis is a life-threatening acute metabolic disorder that is characterized by absolute or relative deficiency of circulating insulin and increased counter regulatory hormone levels in the circulation. The entity may be the presenting clinical picture or may occur at any time after diagnosis in type 1 diabetes. After diagnosis, major causative factors are forgetting insulin dose or intercurrent infections. The diagnosis depends on clinical suspicion and subsequent confirmation via biochemical tests (namely, hyperglycemia, metabolic acidosis, and ketonuria/ketonemia). Therapy consists of correction of fluid and electrolyte disorders, insulin administration, and careful ongoing monitoring of clinical and laboratory factors. The success of diabetic ketoacidosis treatment depends on the appropriate correction of dehydration, hyperglycemia, ketoacidosis, and electrolyte imbalance. In children, mortality is frequently associated with cerebral edema and encountered in 0.5-3% of all diabetic ketoacidosis episodes. It mostly reported in children with newly diagnosed diabetes and the exact mechanisms are unknown. The most important signs and symptoms of cerebral edema include severe headache, sudden deterioration in mental status, bradycardia, hypertension, cranial nerve dysfunction, and incontinence. Failure of the serum sodium to increase with treatment, intravenous administration of sodium bicarbonate, degree of hypocapnia and dehydration are the most important risk factors. Mannitol (0.25-1 g/kg, 20-30 minute) or 3% NaCL (5-10 mL/kg, 30 minute) treatment should be given immediately in any clinical suspicion or finding, and following the rate of fluid must be reducing. Many cases of diabetic ketoacidosis can be prevented by a better education of patients and health care providers and an easier access to medical care. Copyright © 2010 by Türkiye Klinikleri.


Bahceci B.,Recep Tayyip Erdogan University | Bagcioglu E.,Afyon Kocatepe University | Ozturk A.,Bolge Egitim ve Arastirma Hastanesi | Bulbul F.,University of Gaziantep | And 3 more authors.
Complementary Therapies in Clinical Practice | Year: 2013

Purpose: The aim of this study was to determine the prevalence of complementary and alternative medicine (CAM) use and the associated socio-demographic factors among patients with mental disorders in the Turkish community. Methods: One thousand and twenty-seven patients with a diagnosis of mental disorders who were attending psychiatric outpatient clinics in five Turkish cities were interviewed. A survey questionnaire, which included questions on socio-demographic characteristics and CAM use, was administered face-to-face by psychiatrists. Results: 22.2% of patients with mental disorders were using some form of CAM in the Turkish community. CAM and medication concurrent users had a higher level of education and income compared to CAM users only or medicine users only ( p<0.001). The most common type of CAM used was herbal therapy ( n=146, 64%). Conclusion: Use of CAM by patients with mental disorders should be investigated and taken into account by psychiatrists. © 2013 Elsevier Ltd.


Balta I.,Kecioren Egitim ve Arastirma Hastanesi | Balta S.,Gulhane Askeri Tip Akademisi | Demirkol S.,Gulhane Askeri Tip Akademisi
Gulhane Medical Journal | Year: 2014

Psoriasis isa chronic inflammatory disease that affectsapproximately 1-3% of the population. Psoriasis is associated with conventional cardiovascular risk factors, including hypertension, diabetes mellitus, obesity, smoking and hyperlipidaemia. Furthermore, psoriasis, like other type 1 helper T-cell-driven inflammatory disorders such as rheumatoid arthritis and systemic lupus erythromatosus, is an independent risk factor for atherothrombotic disease. Because of psoriasis and atherosclerosis are both characterized by T helper 1 and T helper type 17 activation and reduced T regulatory cell function. Therefore, psoriasis is associated with increased risk of adverse cardiovascular events. Young age, severe skin affection ano/or psoriatic arthritis carry the most risk. The high-risk group of patients with psoriasis may be candidates for early cardiovascular risk factor modification. © Gülhane Askeri Tip Akademesi 2014.


Goz I.,Acibadem University | Karahan S.K.,Kecioren Egitim ve Arastirma Hastanesi | Tekcan A.I.,Bogazici University
Journal of Obsessive-Compulsive and Related Disorders | Year: 2016

Previous research on memory and metamemory processes in obsessive compulsive disorder (OCD) almost exclusively addressed veridical memory. The present study investigated veridical and false memory (recall and recognition of nonpresented information) as well as confidence in OCD. We compared checker OCD, non-checker OCD, and healthy control participants (HC) by using the Deese-Roediger-McDermott (DRM) false memory paradigm. Participants were given word lists, each of which consisted of semantically related words which were strong associates of a non-presented critical target word. They were then given a free recall and a recognition task. Although both OCD groups showed comparable correct recall and recognition performance to that of the HC group, OCD groups were less prone to false memories and reported lower confidence for these false memories than the HC group. Accuracy of global recognition estimates were similar across three groups. This pattern of results may partly be due to OCD groups' reliance on item-based rather than relational processing at encoding. © 2016 Elsevier Inc.


Demir M.,Kecioren Egitim ve Arastirma Hastanesi | Tuncay E.,Yedikule Gogus Hastaliklari ve Gogus Cerrahisi Egitim ve Arastirma Hastanesi | Yenturk E.,Yedikule Gogus Hastaliklari ve Gogus Cerrahisi Egitim ve Arastirma Hastanesi | Kanmaz D.,Yedikule Gogus Hastaliklari ve Gogus Cerrahisi Egitim ve Arastirma Hastanesi
Anatolian Journal of Clinical Investigation | Year: 2014

To determine the influence of frequent exposure on the risk of tuberculosis and to define some features of employee who had tuberculin skin test conversion in a chest diseases hospital and a general hospital without a chest diseases clinic.In this observational study, to determine tuberculin skin test conversion and compare the risks of tuberculosis among health care workers, tuberculin skin tests were performed two times, at least one year apart, in the study hospitals. An increase of 10 mm and above in size was accepted as conversion. Chi square test and correlation analysis were used for the statistical analysis.In total, 201 subjects had two tuberculin skin tests, 12 to 18 months apart. The test was found positive in 60 subjects out of 134 (44.7%) in the chest diseases hospital and in 4 subjects out of 67 (%5.9) in the general hospital. Tuberculosis risk was 7.4 times higher among chest disease hospital's health care workers and it was statistically significant.The tuberculosis infection risk was significantly greater in health care workers who expose to tuberculosis more frequently. If necessary preventive measures are taken, the tuberculosis infection risk will decrease significantly.

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