Kbn College

Vijayawāda, India

Kbn College

Vijayawāda, India
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Panduranga Rao J.,KBN College | Jyothi K.,Government College | Srinivas G.,Andhra Loyala College
Rasayan Journal of Chemistry | Year: 2017

Density (ρ), ultrasonic velocities (u) and dynamic viscosity (η) for three binary clusters of Trichloroethylene with 1- pentanol, 1-hexanol and 1-heptanol are experimented at ambient temperature 303.15K at atmospheric pressure over various compositions. The density and viscosity are calibrated using Specific gravity bottle and Ostwald’s glass capillary viscometer respectively. The velocity is measured using ultrasonic interferometer. Molar volume, adiabatic compressibility, Intermolecular free length, and Wada’s Constant are calculated using the above measured values. The excess parameters viz., excess molar volume, excess adiabatic compressibility, excess intermolecular free length, viscosity deviation are also deducted from experimental values. Intermolecular interactions, and structural interactions present in various mixture are discussed in detail. © RASĀYAN. All rights reserved.

Krishnaveni G.,Kbn College | Sathyannarayana P.V.V.,ANU
International Journal of Pharma and Bio Sciences | Year: 2013

A simple, rapid reverse phase High-performance liquid chromatographic method was developed and validated for the simultaneous estimation of Famotidine and Ibuprofen in bulk and pharmaceutical dosage forms. Chromatography was carried out by using Chromosil C-18,column having 250 x 4.6mm internal diameter with a mixture of Water, Acetonitrile and T.E.A in the ratio of 80:10:10 (v/v/v) as mobile phase. Determination of the different analytical parameters such as linearity, precision, accuracy, and specificity, limit of detection (LOD) and limit of quantification (LOQ) was done. The calibration curve was found to be linear for each analyte in the desired concentration range. The % recovery was found to be 99.74 and 100.74 for Famotidine and Ibuprofen respectively. The proposed method is highly sensitive, precise and accurate, which was evident from the LOD value of 1.5 and 0.5 ppm for Famotidine and Ibuprofen respectively and hence the present method can be applied successfully for the quantification of active pharmaceutical ingredient (API) content in the combined formulations of Famotidine and Ibuprofen.

Krishnaveni G.,Kbn College | Sathyannaryana P.V.V.,Acharya Nagarjuna University
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2012

A simple, precise and accurate RP-HPLC method was developed and validated for rapid assay of celecoxib in tablet dosage form. Isocratic elution at a flow rate of 1.5ml/min was employed on a symmetry Chromosil C18 (250×4.6mm, 5 μm in particle size) at ambient temperature. The mobile phase consisted of Methanol: ACN: 60:40 (V/V). The UV detection wavelength was 220 nm and 20 μl sample was injected. The retention time for celecoxib was 3.57 min. The percentage RSD for precision and accuracy of the method was found to be less than 2%. The method was validated as per the ICH guidelines. The method was successfully applied for routine analysis of celecoxib in tablet dosage form and bulk drug.

Lakshmana Rao G.,Acharya Nagarjuna University | Sandhya Sri P.B.,KBN College | Satyanarayana G.R.,ChSDT College
Der Pharma Chemica | Year: 2015

Theoretical values of ultrasonic velocity in binary liquid mixtures of ethyl benzoate + 2- methyl -1- propanol, ethyl benzoate + 2-butanol and ethyl benzoate + 2- methyl -2- propanol have been evaluated at 303.15,308.15,313.15 and 318.15K using Nomoto's relation, ideal mixing relation (IMR) impedance dependence relation (IDR), Rao's velocity method (RVM) and Junjie's method (JM). The relative merits of these theoretical relations were examined by comparing the theoretical values of ultrasonic velocity with the values obtained experimentally. The validity of the theories was checked by applying the chi-square test for goodness of fit and by calculating the average percentage error (APE).

Krishnaveni G.,Kbn College | Bhagyakumar T.,Kbn College | Sailaja O.,Kbn College
International Journal of Pharma and Bio Sciences | Year: 2015

VTPS is one of the major sources for electricity to Andhra Pradesh state. It was located in Kondapalli village in Vijayawada-Hyderabad National Highway. Approximately 13 villages are there around of VTPS. In VTPS electricity is produced by rotating of turbines with steam of Krishna river water. Present paper deals with the impact of pollution on ground water at Ibrahimpatnam nearby VTPS. During investigation ground water is collected from 6 different locations of Ibrahimpatnam to evaluate physicochemical parameters such as pH, Alkalinity, DO, BOD, COD, Chloride, Electrical conductance, Nitrate, Phosphate and heavy metals. The investigation reveals that the six locations have an impact by VTPS effluents on Ground water.

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