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Harsha N.S.,Katuri Medical College and Hospital | Katti K.,MVJ Medical College and Hospital
Biomedicine (India) | Year: 2012

Recurrent abdominal pain is a common symptom which may,at times need invasive procedures for diagnosis.Hereditary angioedema is a rare cause of recurrent abdominal pain.Here we report two members of a family presenting with recurrent abdominal pain and occasional edema of the limbs.A diagnosis of hereditary angioedema was done by doing a quantitative assay of c1 esterase inhibitor.

Malleshappa K.,PES Institute of Medical science and Research | Harsha N.S.,Katuri Medical College and Hospital | Dhanunjaya Y.,PES Institute of Medical science and Research
Biomedicine | Year: 2011

Background & Objectives: To study the role of adiponectin & Leptin & their ratio as early predictors of micro vascular complications in type I Diabetes mellitus patients. Materials & Methods: The study was conducted on 80 type I diabetes mellitus patients (40 normoalbuminuric & 40 microalbuminuric). Clinical, demographic characteristics and kidney function tests were monitored. Plasma levels of adiponectin, leptin, Interleukin-6 (IL-6) and the high sensitive C-Reactive Protein (CRP) were measured. Results: Microalbuminuric subjects showed a significant elevation in adiponectin levels and a significant decrease in leptin levels as compared to normoalbuminuric subjects(p<0.05). Adiponectin showed a significant positive correlation with microalbuminuria concentrations(r=0.243,p=0.04) while leptin showed a significant negative correlation with both fasting blood glucose(r=-0.276,p=0. 01) & glycated hemoglobin A1C(r=-0.262,p=0.04). Adiponectin to leptin ratio showed a strong significant positive correlation with fasting plasma glucose(r=0.345,p=0.008) & glycated hemoglobin A1C(r=0.286,p=0.02) & with microalbu minuria(r=0.277,p=0.01),& a negative correlation with urine creatinine(r=-0.249,p=0.04). Conclusion: Adiponectin & leptin are better predictors of micro vascular complications than low grade inflammatory markers, moreover adiponectin/leptin ratio can be used as an early, reliable and sensitive predictor for the micro vascular complications monitored by micro albuminuria concentration and glycemic control indices.

Narra R.,Katuri Medical College and Hospital | Mandapalli A.,Advanced Diagnostic Center | Kamaraju S.K.,Katuri Medical College
Journal of Clinical Imaging Science | Year: 2015

Acute necrotizing encephalopathy (ANE) is a rapidly progressing neurologic disorder that occurs in children after common viral infections of the respiratory or gastrointestinal systems. This disease is commonly seen in East Asia. Normal healthy infants and children can get affected. The condition carries a poor prognosis with high morbidity and mortality rates. We report here a case of a 23-year-old female with ANE and describe its neuroimaging findings. Magnetic resonance imaging examination performed showed symmetric lesions involving the thalami, brainstem, and cerebellum. Copyright: © 2015 Narra R.

Sameera K.,Katuri Medical College and Hospital | Sunitha T.,Katuri Medical College and Hospital | Naveen Kumar P.,Katuri Medical College and Hospital | Sujatha P.,Era Medical College and Hospital
International Journal of Pharma and Bio Sciences | Year: 2013

Typhoid fever is a systemic life-threatening infection caused by the bacterium Salmonella enterica serotype Typhi occurring more frequently in underdeveloped regions of the world due to overcrowding and poor sanitation. Initiation of appropriate therapy decreases severity and clinical outcome of the disease which requires early and accurate diagnosis. Pathogenesis due to typhoid leads to various biochemical alterations. Present study was undertaken to investigate serum LDH activities in typhoid fever and to assess its clinical utility as a biochemical marker in typhoid fever. Comparison of LDH levels were also done in other fevers and healthy controls. Other parameters were also investigated viz, serum urea, serum creatinine, serum sodium and serum potassium. In the present study we observed a statistically significant increase in concentrations of LDH in typhoid fever patients when compared with other fever patients and in healthy controls. Other parameters did not exhibit any statistical significance.

Jogdand K.S.,Katuri Medical College and Hospital | Yerpude P.N.,Katuri Medical College and Hospital
Indian Journal of Public Health Research and Development | Year: 2014

Background: Hypertension becoming common health problem worldwide because of increasing longevity and prevalence of contributing factors such as obesity, physical inactivity and an unhealthy diet. Objective: To study the prevalence of risk factors for hypertension among women in rural area of South India Material and method: A community based cross-sectional study was conducted among 837 women selected from rural area of Andhra Pradesh from January to June 2008 Results: Out of 837 women,22.58% were hypertensive. The age specific prevalence of hypertension was maximum(50.44%) in the age group > 60 yrs. Risk factors such as family h/o HTN, h/o DM, tobacco use, waist circumference and BMI were significantly associated with hypertension. Conclusion: Problem of hypertension is increasing among rural women so health education strategies should be directed towards rural women also. © 2014 Indian Journal of Public Health Research and Development. All rights reserved.

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