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Narra R.,Katuri Medical College and Hospital | Mandapalli A.,Advanced Diagnostic Center | Kamaraju S.K.,Katuri Medical College
Journal of Clinical Imaging Science | Year: 2015

Acute necrotizing encephalopathy (ANE) is a rapidly progressing neurologic disorder that occurs in children after common viral infections of the respiratory or gastrointestinal systems. This disease is commonly seen in East Asia. Normal healthy infants and children can get affected. The condition carries a poor prognosis with high morbidity and mortality rates. We report here a case of a 23-year-old female with ANE and describe its neuroimaging findings. Magnetic resonance imaging examination performed showed symmetric lesions involving the thalami, brainstem, and cerebellum. Copyright: © 2015 Narra R.


Ketavarapu S.,Katuri Medical College and Hospital | Uma Ramani G.,Katuri Medical College and Hospital | Modi P.,Osmania Medical College
Journal of Clinical and Diagnostic Research | Year: 2013

Background: Adenosine Deaminase (ADA) has been suggested to be an important enzyme which is associated with the cell mediated immunity, but its clinical significance in typhoid fever has not yet been characterized. The present study was taken up to evaluate the serum ADA activity in patients of typhoid fever. The levels of ADA were also measured in the patients who were suffering from other febrile illnesses. Material and Method: This was a case control study. The subjects who were included in this study were divided into 3 groups. Group A consisted of 50 normal healthy individuals who served as the controls. Group B consisted of 50 patients, both males and females of all age groups, who were suffering from culture positive typhoid fever. Group C consisted of 50 patients who were suffering from febrile illnesses other than typhoid fever like viral fever, gastro enteritis, malaria, tonsillitis, upper respiratory tract infections, etc. The serum levels of ADA were estimated in all the subjects who were under study. Results: The serum ADA level was found to be increased in the patients of typhoid fever as compared to that in those with other febrile illnesses and in the controls. Conclusion: From the present study, it can be concluded that there was a statistically significant increase in the serum ADA levels in the patients with typhoid.


Dhulipalla S.,Katuri Medical College and Hospital
Indian Journal of Otolaryngology and Head and Neck Surgery | Year: 2014

Inferior turbinate hypertrophy is one of the major causes of nasal airway obstruction. Medical treatment often produces insufficient improvement. In these cases, surgical reduction of inferior turbinate can be proposed. Many different techniques are currently available. The aim of our study is to prospectively evaluate the effectiveness of three techniques i.e., electrocautery, cryotherapy and radiofrequency by comparing the response of patients to these three surgical modalities of turbinate reduction. A total of 90 patients presenting with nasal obstruction with or without allergic symptoms, fulfilling the inclusion and exclusion criteria, attending ENT OPD are included in the study. A prospective study was conducted on three groups of thirty patients with symptoms and signs of nasal obstruction associated with inferior turbinate hypertrophy of more than 3 months duration. Then the percentage of subjective improvement in nasal airway is used to assess treatment outcomes 1week, 1, 3, 6, 9 and 12 months after surgery. At the end of 12 months, 56.6 % of patients treated with electrocautery and 56.6 % of patients treated with cryotherapy showed 75 % improvement in nasal obstruction whereas 59.99 % of patients treated with radiofrequency showed 100 % improvement. No statistical difference in the amount of improvement in nasal obstruction was noted between the three treatment groups at the end of 12 months because of relatively small sample size. But clinically radiofrequency showed better subjective improvement in nasal obstruction when compared to cryotherapy and electrocautery. © 2014, Association of Otolaryngologists of India.


Sameera K.,Katuri Medical College and Hospital | Sunitha T.,Katuri Medical College and Hospital | Naveen Kumar P.,Katuri Medical College and Hospital | Sujatha P.,Era Medical College and Hospital
International Journal of Pharma and Bio Sciences | Year: 2013

Typhoid fever is a systemic life-threatening infection caused by the bacterium Salmonella enterica serotype Typhi occurring more frequently in underdeveloped regions of the world due to overcrowding and poor sanitation. Initiation of appropriate therapy decreases severity and clinical outcome of the disease which requires early and accurate diagnosis. Pathogenesis due to typhoid leads to various biochemical alterations. Present study was undertaken to investigate serum LDH activities in typhoid fever and to assess its clinical utility as a biochemical marker in typhoid fever. Comparison of LDH levels were also done in other fevers and healthy controls. Other parameters were also investigated viz, serum urea, serum creatinine, serum sodium and serum potassium. In the present study we observed a statistically significant increase in concentrations of LDH in typhoid fever patients when compared with other fever patients and in healthy controls. Other parameters did not exhibit any statistical significance.


Jogdand K.S.,Katuri Medical College and Hospital | Yerpude P.N.,Katuri Medical College and Hospital
Indian Journal of Public Health Research and Development | Year: 2014

Background: Hypertension becoming common health problem worldwide because of increasing longevity and prevalence of contributing factors such as obesity, physical inactivity and an unhealthy diet. Objective: To study the prevalence of risk factors for hypertension among women in rural area of South India Material and method: A community based cross-sectional study was conducted among 837 women selected from rural area of Andhra Pradesh from January to June 2008 Results: Out of 837 women,22.58% were hypertensive. The age specific prevalence of hypertension was maximum(50.44%) in the age group > 60 yrs. Risk factors such as family h/o HTN, h/o DM, tobacco use, waist circumference and BMI were significantly associated with hypertension. Conclusion: Problem of hypertension is increasing among rural women so health education strategies should be directed towards rural women also. © 2014 Indian Journal of Public Health Research and Development. All rights reserved.


Yerpude P.N.,Katuri Medical College and Hospital | Jogdand K.S.,Katuri Medical College and Hospital
Indian Journal of Occupational and Environmental Medicine | Year: 2010

Objective: To study the morbidity pattern among cotton mill workers. Material and Methods: This cross-sectional study was conducted in cotton mills in Guntur District (AP) in January 2009 to May 2009. Total 474 workers were included in the study. Results: All study subjects were male. Most of the study subjects belonged to age group 3040 years (56.96%) and lower socioeconomic status (36.09%) according to modified Kuppuswamy′s classification. The literacy status was varied with 5.70% being illiterate and 37.13% were educated up to primary school. Most of workers were working in Ring frame (41.56%) and majority (58.44%) were working for the last 510 years. Mean height of study subjects was 147.42 cm and mean weight was 55.11 kg. The common morbid conditions found were eosinophilia (18.35%), iron deficiency anemia (28.90%), byssinosis grade 1 (7.80%), dental stains (6.54%), refractive errors (7.80%), chronic bronchitis (4.85%), and upper respiratory tract infection (8.64%).


Sunitha T.,Katuri Medical College and Hospital | Sameera K.,Katuri Medical College and Hospital | Umaramani G.,Katuri Medical College and Hospital
International Journal of Pharma and Bio Sciences | Year: 2012

Hypertensive disorders complicating pregnancy are common and form great triad along with hemorrhage and infection. They are one of the important causes resulting in maternal and fetal morbidity and mortality. Metabolic syndrome is a combination of medical disorders that, when occurs together, it increases the risk of developing cardiovascular disease and diabetes. In order to know the risk of development of metabolic syndrome in women with PIH, the risk factors for metabolic syndrome like total cholesterol, HDL cholesterol, triglycerides and fasting blood sugar levels of PIH women as compared to their normotensive counterparts have been measured, analyzed and compared with earlier studies. The PIH women group exhibited highly significant increase in fasting blood sugar level, significant increase in total cholesterol and triglyceride levels and an insignificant decrease in HDL cholesterol. These results indicate that there is a significant association of abnormal lipid profiles and increased fasting blood sugar levels in PIH women.


PubMed | Asha Hospital and Katuri Medical College and Hospital
Type: Journal Article | Journal: Indian journal of psychological medicine | Year: 2016

After 1 year of introduction of olanzapine long-acting injectable (LAI) in India, many psychiatrists believe that it is a very affordable, well-tolerated, and effective second generation long-acting antipsychotic depot compared to not well tolerated but cheap first generation antipsychotic depots and to other second generation depots which are costly. However, reports of its possible adverse events in clinical settings are not yet published. We report what probably might be the first case of postinjection delirium/sedation syndrome (PDSS) in India. Although the occurrence is uncommon, incorrect understanding of this event may hinder the future use of the potentially useful olanzapine LAI. We review the available literature on the proposed diagnostic guidelines, mechanism of this event, precautions, and management of PDSS.


PubMed | Katuri Medical College and Hospital
Type: Journal Article | Journal: Anesthesia, essays and researches | Year: 2015

Bilateral recurrent laryngeal nerve (RLN) injury is rare for benign thyroid lesions (0.2%). After extubation-stridor, respiratory distress, aphonia occurs due to the closure of the glottic aperture necessitating immediate intervention and emergency intubation or tracheostomy. Intra-operative identification and preservation of the RLN minimizes the risk of injury. It is customary to expect RLN problems after thyroid surgery especially if malignancy, big thyroid, distorted anatomical problems and difficult airway that can lead to intubation trauma. Soon after extubating, it is essential to the anesthetist to check the vocal cord movements on phonation and oropharyngeal reflexes competency. But this case is specially mentioned to convey the message that in spite of absence of above mentioned predisposing factors for complications and good recovery profile specific to thyroid, there can be unanticipated airway compromise that if not attended to immediately may cost patients life. This is a case of postextubation stridor following subtotal thyroidectomy due to bilateral RLN damage and its management.


PubMed | Katuri Medical College and Hospital
Type: Journal Article | Journal: Indian journal of dermatology | Year: 2016

Alopecia areata (AA) is a common, chronic inflammatory disease characterized by nonscarring hair loss on the scalp or any hair-bearing area of the body. Recently, dermoscopy, a noninvasive diagnostic procedure, has been employed for the diagnosis of AA.To evaluate various dermoscopic patterns in AA and correlate these patterns with the disease activity and severity.Dermoscopy was performed on AA patients using DL1 dermoscope (magnification 10 was used). The dermoscopic patterns recorded were analyzed to identify any correlation with the disease activity and severity.A total of fifty patients of AA were recruited in the study. Female outnumbered males with the ratio being 1.173:1. Mean age of the patients was 25.06 years. Mean duration of disease was 14 months. The most common site involved was scalp (80%) and type noted was patchy (84%). Various dermoscopic patterns noted were yellow dots (YD) (88%), short vellus hair (66%), black dots (BD) (58%), broken hairs (BHs) (56%), tapering hair (TH) (26%), Coudability hairs (14%), pigtail hair (14%), and Pohl-Pinkus constrictions (2%). Statistically significant correlation was observed between BD, BHs, THs, and disease activity. No significant correlation was found between severity and any of the dermoscopic features.The most common dermoscopic pattern in our study was YD. Presence of BDs, BHs, and THs indicate active disease. Dermoscopic patterns were not affected by severity of the disease.

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