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Mallick A.,Kashipur Michael Madhusudan Mahavidyalaya | Das P.,Jadavpur University | Chattopadhyay N.,Jadavpur University
Journal of Photochemistry and Photobiology C: Photochemistry Reviews | Year: 2010

The photobehavior of norharmane (9H-pyrido[3,4-b]-indole) (NHM), one of the vastly used skeleton of drugs in therapeutic applications, has recently been the subject of increasing interest due to the finding of their phototoxic and photocarcinogenic properties. Its absorption and fluorescence behavior from different prototropic species show remarkable sensitivity towards the polarity, viscosity and local pH, exhibited by various microheterogeneous bio and biomimetic environments like micelles, reverse micelles, proteins, etc. The significant results obtained for NHM in homogeneous and a series of microheterogeneous environments is reviewed in this account. Much attention has been given to the properties of the excited states, location and biodistribution of NHM in different biological environments. The results can help in understanding the photophysics of the probe in biological environments and in assessing the correlation between different prototropic forms and biological activity. © 2010.

Mallick A.,Kashipur Michael Madhusudan Mahavidyalaya | Haldar B.,University of Burdwan | Roy U.K.,Deshabandhu Mahavidyalaya
Chemical Physics Letters | Year: 2013

Steady state absorption, emission, and picosecond time resolved fluorescence and transmission electron microscopic (TEM) techniques have been exploited to substantiate and characterize the formation of a substrate - anchored β-cyclodextrin nanotubular suprastructure in aqueous medium. Experimental results reveal that suprastructure is originated from a purely ground state interaction between a newly developed bisindole based drug molecule namely 3,3′-bis(indolyl)-4-chlorophenylmethane (BICPM) with β-cyclodextrin. The bound drug molecule is susceptible to be released out from the supramolecular complex in a controlled manner by the use of endogenous surfactants and is poised to serve a significant purpose in targeted drug delivery preferably at the intestinal region. © 2013 Elsevier B.V. All rights reserved.

Mondal S.,Indian Institute of Science | Das T.,Indian Institute of Science | Ghosh P.,Indian Institute of Science | Maity A.,Indian Institute of Science | And 2 more authors.
Chemical Communications | Year: 2013

Surfactant bilayer protected core-shell carbon nanoparticles (CNPs) have been synthesised. Förster resonance energy transfer (FRET) between the core-shell CNPs and two strategically chosen organic dyes has been exploited to characterise the protective surfactant bilayer. This journal is © The Royal Society of Chemistry.

Mondal S.,Indian Institute of Science | Chatti M.,Indian Institute of Science | Mallick A.,Kashipur Michael Madhusudan Mahavidyalaya | Purkayastha P.,Indian Institute of Science
Chemical Communications | Year: 2014

Dopamine functionalized carbon nanoparticles (CNPs) that can act as efficient photoinduced electron donor-acceptor systems depending on the pH of the medium have been synthesized. In acidic media, dopamine on CNPs exists as hydroquinone and serves as an electron donor while under alkaline conditions the corresponding quinone form of dopamine serves as a strong electron acceptor. Application of external NADH to the system can invert the donor-acceptor roles under alkaline conditions. © the Partner Organisations 2014.

Roy P.,Kashipur Michael Madhusudan Mahavidyalaya | Sreekesh S.,Jawaharlal Nehru University
Proceedings of the 16th International Association for Mathematical Geosciences - Geostatistical and Geospatial Approaches for the Characterization of Natural Resources in the Environment: Challenges, Processes and Strategies, IAMG 2014 | Year: 2014

Physical alteration of soil characteristics of especially the plough layer (0-20cm) is brought about through land culture.The type of land cover, in fact, is an important factor controlling the soil texture, soil organic carbon (SOC) and soil erosion.The objectives of this paper areto analyze soil particle size distribution in the plough layer and quantify the SOC storage in the finer soil separate under native vegetation cover, cultivated land, eucalyptus plantations and barren land.A digital land cover map of the study area has been generated using Resourcesat-2 image.Soil samples from plots under different land cover types have been collected from depths of 0-10 cm and 10-20 cm.Particle size analysis has been done by dry sieving.SOC content of each soil separate - sand, very fine sand, silt + clay, under different land cover, has been done with the help of Walkley and Black method.Analysis of particle size distribution showed that proportion of sand particle is high.However silt+clay proportions have been found to vary with land cover types.SOC was high in silt+clay particles in general; but tended to increase in the sand fractions when particulate organic matter is incorporated.SOC decreased with soil depth under all land cover conditions but showed a reverse trend in some plots of cultivation. © 2014, Capital Publishing Company.

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