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Dharwad, India

Prashanth M.S.,Kuvempu University | David M.,Karnataka Science College
Bulletin of Environmental Contamination and Toxicology | Year: 2010

Activities of ATPase in different organs of Cirrhinus mrigala exposed to cypermethrin with lethal (5.13 μg/L) and sublethal (1.02 μg/L) concentration was investigated. Decrease of Na +-K +-ATPase activity was observed in gills, liver and muscle to about 60.22%, 22.13% and 48.89% respectively, by lethal concentration. Whereas in sublethal concentration activity was increased to about 7.84%, 10.70% and 5.96%. Similarly, in case of Mg 2+-ATPases activity as 57.61%, 48.82% and 28.59% for lethal and for sublethal it was 10.15%, 4.64% and 11.92%. Ca 2+-ATPase activity was observed to be 55.24%, 41.66% and 47.66% by lethal and for sublethal it was 8.02%, 24.89% and 6.47%. © 2009 Springer Science+Business Media, LLC. Source

Shettar A.K.,Karnatak University | Kotresha K.,Karnataka Science College | Kaliwal B.B.,Karnatak University | Vedamurthy A.B.,Karnatak University
Asian Pacific Journal of Tropical Disease | Year: 2015

Objective: To evaluate in vitro antioxidant and anti-inflammatory activity of Ximenia americana extracts. Methods: Herbal extraction was done by Soxhlet extraction method with increasing polarity of solvents viz., chloroform, ethyl acetate, methanol, ethanol and water. Phytochemical analysis was done using different biochemical tests. Antioxidant potential of plant extracts were analyzed by ferric ion reducing antioxidant power, phosphomolybdenum and 2,2-diphenyl-1-picrylhydrazyl, and anti-inflammatory activity by using protein denaturation in vitro bioassay. Total phenolic content of each extract was also determined to assess their corresponding effect on antioxidant capacity of plant. Results: Phytochemical analysis showed that each solvent extract contained broad spectrum of secondary metabolites, phenolic compounds, flavonoids, tannins and glycosides, whereas compared to other solvent extracts, chloroform extract showed negative result for phenolic compounds whereas aqueous extract exhibited the highest phenolic content and the significant antioxidant capacity based on the test performed. Out of all extracts, methanol extract showed high anti-inflammatory activity. Conclusions: The present study revealed that different solvent extracts of Ximenia americana leaves contain broad spectrum of bioactive compounds. Results confirm that aqueous extract exhibited high antioxidant activity and methanol extract exhibited high anti-inflammatory activity. Further study requires purification, characterization and structural elucidation of phenolic compounds in both extracts that may help in the development of new phytopharmaceuticals. © 2015 Asian Pacific Tropical Medicine Press. Source

Sunil Kumar R.K.,University of Mysore | Suresh Kumar B.V.,University of Mysore | Manjunatha S.,Karnataka Science College
Nature Environment and Pollution Technology | Year: 2012

Assessment of surface and groundwater quality has been carried out in the parts of the Sandur schist belt, Bellary district, Karnataka, South India. Sandur schist belt is well known for iron ore deposits. Rigorous and unplanned mining methods causes intensive natural hazards like water pollution, air pollution, noise pollution, dust pollution, etc. Water quality of the study area has been studied for sodium (Na), potassium (K), calcium (Ca), magnesium (Mg), chloride (Cl), fluoride (F), sulphate (SO 4), nitrate (NO 3) and total hardness. Results show gradual decrease in groundwater quality and surface water pollution in and around the parts of Sandur Schist belt. Mapping of re-vegetation site selection at regional scales is essential for a wide range of applications including landslide, erosion, land planning, global warming, LU/LC alterations (especially on human activities), effect of climate, natural hazard and socio-economic dynamics in global and local scale. In this study, re-vegetation site selection has been carried out by using remote sensing and Geographic Information System (GIS) in Sandur schist belt in Bellary District. Identification potential sites for replantation within the mining pit is a complicated thing using change detection comparison (pixel by pixel). Source

Dodamani A.F.,Karnataka Science College
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2012

The study of the adduct formation of Ni(Il) di(3-chloro,2-methylphenyl) carbazonate has been undertaken by synthesising and characterizing it by magnetic susceptibility, UV-VIS, IR and 'H-NMR spectral measurements. The distorted square planar Ni(TT) chelate forms adducts with heterocyclic nitrogen bases; spectrophotometric method has been employed for the study of the adduct formation in a monophase chloroform. Both bidentate and unsaturated monodentate heteronuclear nitrogen bases form hexacoordinated adducts with 1:1 and 1:2 stoichiometry, respectively (metalchelate:base). However, the saturated nitrogen bases form pentacoordinated adducts with 1:1 stoichiometry. The results are discussed in terms of basicity and steric factors of the bases. Source

Havanur V.C.,Karnatak University | Badiger D.S.,Karnatak University | Ligade S.G.,Karnataka Science College | Gudasi K.B.,Karnatak University
Der Pharma Chemica | Year: 2011

The heterocyclic ligand 2-anilino-N'-[(1E)-1-pyridin-2-ylethylidene]acetohydrazide (Apeah) was synthesized by coupling of 2-anilinoacetohydrazide with 2-acetylpyridine and characterized by IR, 1H and 13C-NMR spectra, it was then reacted with Lanthanide(III) nitrates to form complexes of the type [Ln(Apeah) 2 NO 3 H 2O]·2NO 3 where, Ln = La(III), Pr(III), Nd(III), Sm(III), Eu(III), Gd(III), Tb(III), Dy(III), Y(III). The metal complexes were characterized on the basis of elemental analysis, molar conductance, magnetic susceptibility measurements, TG/DTA and spectral (IR, 1H and 13C-NMR, UV-Visible and EPR) studies. The spectral data revealed that the Apeah behaves in tridentate fashion coordinating through carbonyl oxygen, azomethine nitrogen and pyridine nitrogen. The molar conductance values adequately supported their 1:2 electrolytic natures. Both Apeah and complexes were screened for their antimicrobial study. An enhancement of antimicrobial activity of the Apeah was observed on complexation. Source

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