Karnataka Institute of Medical science KIMS

Hubli, India

Karnataka Institute of Medical science KIMS

Hubli, India
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Kammar K.F.,Karnataka Institute of Medical science KIMS
Journal of Clinical and Diagnostic Research | Year: 2012

Background: A prolonged QT interval is a biomarker for ventricular tachyarrhythmias and a risk factor for sudden death. It is associated with a faulty storage of excess iron in the myocardium, which is described in several hereditary and acquired conditions. However, we do not have enough evidence on the fact that iron deficiency can affect the QT interval. We hypothesized that iron plays an important role in the generation and the propagation of electrical impulses at the level of the myocardial membrane and that it alters the QT interval; so we recorded the QT interval in severely anaemic, non-pregnant females and compared it with that in age and sex matched controls. Methods: 30 non-pregnant females with severe iron deficiency anaemia, Haemoglobin- <6gm% and low serum ferritin levels were subjected to the ECG test. The QTc of each subject was calculated by using Bazzet's formula and this was compared with that of an equal number of sex and age matched controls. Results: A significantly shortened QTc was observed in severe iron deficiency anaemia (SIDA) (390±23ms) as compared to that in the controls (419±19ms) (P>0.001). There was a significant positive correlation between the serum ferritin levels and the QTc interval. Conclusion: A shortened QTc was observed in the SIDA group because of the sympathetic over activity which was secondary to the hyper dynamic circulation.


Torvi J.R.,Karnataka Institute of Medical science KIMS | Dambal S.,Karnataka Institute of Medical science KIMS
Current Pediatric Research | Year: 2011

A prescription by a doctor may be taken as a reflection of physician's attitude to the disease and the role of drug in its treatment. Feedback from the study would help both the pre-scriber and institutional authorities to review their prescribing practices and modify if necessary to facilitate better health care delivery. To evaluate the prescription patterns and to generate data on rational/irrational prescribing in patients suffering from upper respiratory tract infections attending paediatric OPD at a tertiary hospital. A prospective cross sectional study was conducted and the prescription data of patients with upper respiratory tract infection were collected for a period of three months. A total of 667 drugs were prescribed to 300 patients suffering from upper respiratory tract infection. Drug classes with largest representation were the antibiotics (37%). Penicillins represented the largest antibiotic drug class (76%). The most commonly used group of drugs were antibiotics out of which penicillins were largely prescribed. From the data it is understood that the administration of antibiotics was inappropriate as the duration of treatment was insufficient (3 days). Over prescription of antibiotic for insufficient duration may increase the risk of resistance.


Mahadevappa K.,Karnataka Institute of Medical Science KIMS | Prasanna N.,Karnataka Institute of Medical Science KIMS | Channabasappa R.A.,Karnataka Institute of Medical Science KIMS
Journal of Clinical and Diagnostic Research | Year: 2016

Introduction: Female sterilization is one of the best and effective methods of contraception for women who have completed their family. Tubectomy during caesarean operation and minilaparotomy are popular methods in developing countries whereas laparoscopic sterilization and hysteroscopic tubal occlusion are the preferred methods in developed countries. Aim: To know the trends, incidence and immediate complications of methods of female sterilizations performed at our institute. Materials and Methods: This is a retrospective analytical study conducted at our tertiary care centre from January 2010 to December 2014 in Karnataka Institute of Medical Sciences, Hubli, Karnataka. The case files of all the patients who underwent sterilization were taken from the medical records section and reviewed in detail. The cases were grouped as caesarean tubectomy, minilaparotomy and laparoscopic sterilization, based on the abdominal entry. For minilaparotomy and during caesarean tubectomy, modified pomeroy’s technique was used. For laparoscopic sterilization, falope rings were used. Data was analysed by Karl Pearson’s correlation co-efficient method and Chi-Square test. The p-value < 0.05 was considered significant.Results: Out of 5442 cases of female sterilization, 2872 underwent caesarean tubectomy, remaining half underwent minilaparotomy (1306) and laparoscopic sterilization (1264). Sterilizations were significantly more during puerperal period (caesarean tubectomy + post abortal + postpartum) c mpared to interval period. There was an increasing trend in caesarean tubectomy and laparoscopic sterilization. There were 11 procedure related complications in the laparoscopic sterilization, one in caesarean tubectomy and none in minilaparotomy. Two deaths were reported in minilaparotomy, one in laparoscopic sterilization and four in the caesarean tubectomy, which were due to septicaemia. Conclusion: An increasing trend in caesarean tubectomy and laparoscopic sterilization is seen in this study. Female sterilization should be individualized based on the timing, place and surgeons experience. Sepsis is a major cause of death and asepsis could be compromised when female sterilization is done in large numbers in camps. Hence target related approach towards female sterilization should be avoided. Laparoscopic sterilization has more procedure related complications, which can be better handled in tertiary care centres. © 2015, Journal of Clinical and Diagnostic Research. All rights Reserved.


Kabadi Y.M.,Korea Institute of Materials Science | Harsha B.,Karnataka Institute of Medical science KIMS
Journal of Obstetrics and Gynecology of India | Year: 2016

Objective: To study the role of hysterolaparoscopy in the evaluation and management of female infertility. Materials and Methods: A retrospective study of the 94 case files of all the patients who underwent diagnostic hysterolaparoscopy for infertility between January 2014 to June 2015 in the department of Obstetrics and Gynecology, Karnataka Institute of Medical Sciences, Hubli. These infertile women were confirmed to have normal ovulatory cycles, hormonal assays and seminogram report. Dye studies as well as inspection for abnormal pelvic and intrauterine pathology and necessary therapeutic interventions were done during the procedure. Abnormal pelvic and intrauterine pathology by hysterolaparoscopy were categorized. Results: Out of 94 cases, 53.1 % patients had primary, 17.1 % patients had secondary infertility, and 29.8 % came for tubal recanalization. As a whole pelvic pathology was confirmed in 51.7 % and intrauterine pathology in 18.1 % patients by hysterolaparoscopy. The most common laparoscopic abnormality detected was ovarian pathology (20.8 %), followed by pelvic inflammatory disease (17.5 %). Tubal block comprised 7.7 % whereas distorted uterus by fibroid in 6.6 % and pelvic endometriosis in 5.4 %. In hysteroscopy, the incidence of uterine anomaly was 13 (13.8 %). Septate uterus is the most common with a mean incidence of approximately 7 (53.8 %). Conclusion: Diagnostic hysterolaparoscopy is an effective diagnostic and therapeutic modality for certain significant and correctable abnormalities in pelvis, tubes and uterus which are missed by other imaging modalities. © 2016 Federation of Obstetric & Gynecological Societies of India


Torvi J.R.,Karnataka Institute of Medical science KIMS | Hunashal R.D.,Karnataka Institute of Medical science KIMS
International Journal of Pharma and Bio Sciences | Year: 2012

The present study involves extraction, phytochemical investigation and in-vitro antimicrobial activity of Luffa acutangula var amara fruits known as Kadwi turai in Hindi. The phytochemical investigation revealed the presence of sterols and glycoside in chloroform extract. The chloroform extract showed significant antimicrobial activity than aqueous extract. Both extracts showed weak antifungal activities.


PubMed | Karnataka Institute of Medical science KIMS
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2015

One of the treatment modalities for tracheal stenosis is tracheal dilatation and stenting using silicone Montgomery T-tube. Various techniques have been reported for this procedure. For safe anaesthetic management, anaesthesiologist must be aware of the surgical procedure, limitations of T-tube, likelihood of compromised airway besides the inherent problems of sharing the airway with surgeons. Total intravenous anaesthesia (TIVA) is a technique which has become very popular and possible now a days for various surgical procedures owing to its advantages. The anaesthetic technique should be based on the providers experience and severity of tracheal stenosis. We present here the anaesthetic management using TIVA technique with propofol and atracurium for the insertion of Montgomery T-tube in a case of post intubation tracheal stenosis.


PubMed | Korea Institute of Materials Science and Karnataka Institute of Medical science KIMS
Type: Journal Article | Journal: Journal of obstetrics and gynaecology of India | Year: 2016

To study the role of hysterolaparoscopy in the evaluation and management of female infertility.A retrospective study of the 94 case files of all the patients who underwent diagnostic hysterolaparoscopy for infertility between January 2014 to June 2015 in the department of Obstetrics and Gynecology, Karnataka Institute of Medical Sciences, Hubli. These infertile women were confirmed to have normal ovulatory cycles, hormonal assays and seminogram report. Dye studies as well as inspection for abnormal pelvic and intrauterine pathology and necessary therapeutic interventions were done during the procedure. Abnormal pelvic and intrauterine pathology by hysterolaparoscopy were categorized.Out of 94 cases, 53.1% patients had primary, 17.1% patients had secondary infertility, and 29.8% came for tubal recanalization. As a whole pelvic pathology was confirmed in 51.7% and intrauterine pathology in 18.1% patients by hysterolaparoscopy. The most common laparoscopic abnormality detected was ovarian pathology (20.8%), followed by pelvic inflammatory disease (17.5%). Tubal block comprised 7.7% whereas distorted uterus by fibroid in 6.6% and pelvic endometriosis in 5.4%. In hysteroscopy, the incidence of uterine anomaly was 13 (13.8%). Septate uterus is the most common with a mean incidence of approximately 7 (53.8%).Diagnostic hysterolaparoscopy is an effective diagnostic and therapeutic modality for certain significant and correctable abnormalities in pelvis, tubes and uterus which are missed by other imaging modalities.


PubMed | Karnataka Institute of Medical Science KIMS
Type: Journal Article | Journal: Journal of clinical and diagnostic research : JCDR | Year: 2016

Female sterilization is one of the best and effective methods of contraception for women who have completed their family. Tubectomy during caesarean operation and minilaparotomy are popular methods in developing countries whereas laparoscopic sterilization and hysteroscopic tubal occlusion are the preferred methods in developed countries.To know the trends, incidence and immediate complications of methods of female sterilizations performed at our institute.This is a retrospective analytical study conducted at our tertiary care centre from January 2010 to December 2014 in Karnataka Institute of Medical Sciences, Hubli, Karnataka. The case files of all the patients who underwent sterilization were taken from the medical records section and reviewed in detail. The cases were grouped as caesarean tubectomy, minilaparotomy and laparoscopic sterilization, based on the abdominal entry. For minilaparotomy and during caesarean tubectomy, modified pomeroys technique was used. For laparoscopic sterilization, falope rings were used. Data was analysed by Karl Pearsons correlation co-efficient method and Chi-Square test. The p-value < 0.05 was considered significant.Out of 5442 cases of female sterilization, 2872 underwent caesarean tubectomy, remaining half underwent minilaparotomy (1306) and laparoscopic sterilization (1264). Sterilizations were significantly more during puerperal period (caesarean tubectomy + post abortal + postpartum) compared to interval period. There was an increasing trend in caesarean tubectomy and laparoscopic sterilization. There were 11 procedure related complications in the laparoscopic sterilization, one in caesarean tubectomy and none in minilaparotomy. Two deaths were reported in minilaparotomy, one in laparoscopic sterilization and four in the caesarean tubectomy, which were due to septicaemia.An increasing trend in caesarean tubectomy and laparoscopic sterilization is seen in this study. Female sterilization should be individualized based on the timing, place and surgeons experience. Sepsis is a major cause of death and asepsis could be compromised when female sterilization is done in large numbers in camps. Hence target related approach towards female sterilization should be avoided. Laparoscopic sterilization has more procedure related complications, which can be better handled in tertiary care centres.


PubMed | Karnataka Institute of Medical science KIMS
Type: Journal Article | Journal: Journal of cutaneous and aesthetic surgery | Year: 2015

Dumbbell-shaped swellings in neurofibroma have been commonly described in the spine, thorax, cranial cavity, and pelvis; however, dumbbell-shaped swellings in the peripheries are rare. Here, we report a dumbbell-shaped neurofibroma over the pinna in an 18-year-old female patient, its successful surgical management, and its association with Hashimoto thyroiditis. To the best of our knowledge, this is the first ever case to be reported of a dumbbell-shaped neurofibroma over the external ear and only the fourth case of neurofibromatosis type 1 (NF1) to be associated with Hashimoto thyroiditis.


PubMed | Karnataka Institute of Medical science KIMS
Type: Journal Article | Journal: Journal of cutaneous and aesthetic surgery | Year: 2016

A chondroid syringoma (CS) is an exceedingly rare mixed tumor of the skin. These tumors are relatively common in the head and neck area. Occurrence of these tumors in the philtrum is rare, with only two documented cases in English literature to the best of our knowledge. This paper presents a case of CS of the philtral dimple with aesthetically excellent philtrum reconstruction.

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