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Kondo M.,Nagoya University | Mokuno K.,Kariya Toyota General Hospital Kariya | Uemura A.,Nagoya University | Kachi S.,Nagoya University | And 3 more authors.
Clinical Ophthalmology | Year: 2010

We report a case of paraneoplastic retinopathy associated with a retroperitoneal liposarcoma. A 42-year-old man was referred to our hospital with complaints of night blindness and blurred vision in the peripheral field. Electroretinograms showed a progressive amplitude reduction in his both eyes. Abdominal magnetic resonance imaging showed a large retroperitoneal mass, and pathologic examination revealed a dedifferentiated liposarcoma. Western blot analysis showed an antiretinal antibody in the serum of our patient, and his serum reacted with the photoreceptors of a bovine retina. To the best of our knowledge, this is the first case of paraneoplastic retinopathy associated with a liposarcoma. © 2010 Kondo et al, publisher and licensee Dove Medical Press Ltd. Source

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