Kondo M.,Nagoya University |
Mokuno K.,Kariya Toyota General Hospital Kariya |
Uemura A.,Nagoya University |
Kachi S.,Nagoya University |
And 3 more authors.
Clinical Ophthalmology | Year: 2010
We report a case of paraneoplastic retinopathy associated with a retroperitoneal liposarcoma. A 42-year-old man was referred to our hospital with complaints of night blindness and blurred vision in the peripheral field. Electroretinograms showed a progressive amplitude reduction in his both eyes. Abdominal magnetic resonance imaging showed a large retroperitoneal mass, and pathologic examination revealed a dedifferentiated liposarcoma. Western blot analysis showed an antiretinal antibody in the serum of our patient, and his serum reacted with the photoreceptors of a bovine retina. To the best of our knowledge, this is the first case of paraneoplastic retinopathy associated with a liposarcoma. © 2010 Kondo et al, publisher and licensee Dove Medical Press Ltd.