Karachi Institute of Nuclear Medicine and Radiotherapy KIRAN

Karachi, Pakistan

Karachi Institute of Nuclear Medicine and Radiotherapy KIRAN

Karachi, Pakistan
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Islam K.,Gujranwala Institute of Nuclear Medicine and Radiotherapy GINUM | Ul Haque A.,Karachi Institute of Nuclear Medicine and Radiotherapy KIRAN | Hussain M.,Karachi Institute of Nuclear Medicine and Radiotherapy KIRAN | Murad S.,Oncology and Radiotherapy Institute | And 3 more authors.
Journal of Radiotherapy in Practice | Year: 2014

Purpose The main aim was to use pre-calculated correction factors and calibration factors for measurement of accuracy of dose delivery before implementation of such in vivo dosimetry on real patients visiting for first radiation treatment. These factors were verified by generating the most common treatment plans on human phantom except for breast and colon using cobalt-60 unit. Materials and methods Six treatment plans were generated, i.e. nasopharynx, bladder, prostate, brain, larynx and lung of human phantom, total 18 fields were planned keeping in view the correction factors which are to be verified. MULTIDATA Decision Support System 2.5, Shimadzu simulator, Isorad diode-n type, electrometer patient dose monitor and ATOM Adult male human phantom were used. Results and conclusion For 18 fields, the dose delivery was accurate in the range 0·29-6·74%. The deviation between measured and expected doses to nasopharynx, lung, bladder, prostate, brain and larynx cases of human phantom ranged from 1·44-3·89%, 0·29-0·54%, 0·44-6·18%, 0·54-5·16%, 0·33-4·90%, 5·58-6·74%, respectively. In 30 palliative patient cases, the first radiation treatment was also monitored. The accuracy of dosimety ranged from 1·05% to 5·35%. This study is helpful to identify areas of improvement in treatment of patients like quality control/quality assurance (QA) of treatment planning system, beam data modifications, machine repair maintenance, QA audit in radiotherapy. Copyright © Cambridge University Press 2013.


Islam K.,Gujranwala Institute of Nuclear Medicine and Radiotherapy GINUM | Haque A.,Karachi Institute of Nuclear Medicine and Radiotherapy KIRAN | Muhammad K.,Larkana Institute of Nuclear Medicine and Radiotherapy LINAR | Murad S.,Oncology and Radiotherapy Institute | And 3 more authors.
Journal of Radiotherapy in Practice | Year: 2014

Background and purpose The objective was to determine diode characteristics before actual dose verification on human phantom and patients. Materials and methods The reliability and stability of equipment, signal stability, precision, dose response linearity, field flatness, perturbation of radiation dose, plastic to water conversion factor (K pl), ionisation chambers (ICs) and diode calibration were determined. Correction factors for tray (CF tray), wedge (CF wedge), field size (CF FS), SSD (CF SSD), angle (CF angle) and block (CF block) were found. Patient dose monitor, Isorad diode (n-type) and IC (PTW Frieburg), Co-60 unit (Theratron), ATOM Adult male human phantom (Model 701-D, CIRS) were used. Results and conclusion Good signal stability, precise data, and linear dose response, variation of 0·500% and 5·000% in field flatness and perturbation tests, respectively, were noted. K pl was 1·006 for IC PTW Frieburg TW30013, 0114. The diode calibration factor was 0·989. CF tray, CF FS, CF SSD, CF angle, CF block were 1·001, 1·001, 0·997, 1·006 and 0·990, respectively. CF wedge were 1·024, 1·030 and 1·038 for 30°, 45° and 60° wedges, respectively. The verification of above correction factors (CFs) on Nasopharynx and lung of human phantom was also done. Copyright © 2013 Cambridge University Press.

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