Gonzalez-Diaz P.F.,Institute Matematicas Y Fisica Fundamental |
Moruno P.M.,Institute Matematicas Y Fisica Fundamental |
Yurov A.V.,Kant Russian State University
Gravitation and Cosmology | Year: 2010
We work out a multiverse scenario whose physical characteristics enable us to advance the following conjecture: whereas the physics of particles and fields is confined to live in the realm of the whole multiverse formed by finite-time single universes, the physics of our observable universe must be confined to just one of the infinite number of universes where such a universe is consistently referred to an infinite cosmic time. If this conjecture is adopted, then some current fundamental problems that appear when one tries to make compatible particle physics and cosmology-such as the cosmological constant, the arrow of time and the existence of a finite proper size of the horizon-can be solved. © 2010 Pleiades Publishing, Ltd.
Gritsenko V.A.,Kant Russian State University |
Chubarenko I.P.,RAS Shirshov Institute of Oceanology
Oceanology | Year: 2010
The results of qualitative laboratory and numerical experiments on two-dimensional non-linear model are described, aiming at an investigation of the structure of the front of bottom gravity current. Non-coincidence of frontal interfaces in density and velocity fields within the bottom gravity current leading (frontal) part is stated on the base of comparative analysis of numerical and laboratory experiments. This fact is experimentally confirmed by field example of marine water inflow into a brackish lagoon. The density gradient along the stream line is shown to be an additional effective criterion for the localization of the frontal zone. © Pleiades Publishing, Inc., 2010.
Lodochnikova O.A.,RAS Arbuzov Institute of Organic and Physical Chemistry |
Ashirov R.V.,LLC nIOST |
Appolonova S.A.,Federal State Unitary Enterprise |
Litvinov I.A.,RAS Arbuzov Institute of Organic and Physical Chemistry |
Plemenkov V.V.,Kant Russian State University
Russian Journal of Organic Chemistry | Year: 2010
The reactions of 1-methylcycloprop-2-ene-1-carbonitrile with cyclohexa-1,4-diene and alloocimene gave the corresponding 2:1 addition products as a result of consecutive (conjugate) Alder-ene and Diels-Alder reactions. 1-Methylcycloprop-2-ene-1-carbonitrile acts initially as enophile, and in the second step, as dieno- phile. The structure of the adducts was determined by X-ray analysis. © 2010 Pleiades Publishing, Ltd.
Abdullaev S.A.,Russian Academy of Sciences |
Anishchenko S.E.,Kant Russian State University |
Gaziev A.I.,Russian Academy of Sciences
Biophysics | Year: 2010
Impairments of mitochondrial genome are associated with a wide spectrum of degenerative diseases, development of tumors, aging, and cell death. We studied the content of mitochondrial DNA (mtDNA) with mutations and the total content of mutations in the brain and the spleen of mice subjected to X-ray irradiation at a dose of 1-5 Gy at 8-28 days after treatment. In these mice, we studied the number of mutant copies of extracellular mtDNA (ec-mtDNA) and its total content in blood plasma. We estimated mutations in control and irradiated mice using cleavage of heteroduplexes prepared by hybridization of PCR amplicons of mtDNA (D-loop region) mediated by CEL-I endonuclease, an enzyme that specifically cleaves unpaired bases. Changes in the total number of mtDNA copies relative to nuclear DNA were assessed by real time PCR using the ND-4 and GAPDH genes, respectively. We found that the number of mutant mtDNA copies was significantly increased in the brain and the spleen of irradiated mice and reached the maximum level at the eighth day after treatment; it then decreased by the 28th day after treatment. In nuclear genes similar to mutagenesis, mutagenesis of mtDNA in the brain and spleen tissues linearly depended on irradiation dose. In contrast to mutant nuclear genes, most mutant mtDNA copies were eliminated in the brain and spleen tissues, whereas the total content of mtDNA did not change within 28 days after irradiation. Our data show that, during this period, a high level of ec-mtDNA with mutations was observed in DNA circulating in blood plasma with the maximum level found at the 14th day. We suppose that mutant mtDNA copies are eliminated from cells of animals subjected to irradiation during the posttreatment period. Higher content of ec-mtDNA in blood plasma can be considered as a potential marker of radiation damage to the body. © 2010 Pleiades Publishing, Ltd.
Rumyantsev A.V.,Kant Russian State University |
Kharyukov V.G.,Kant Russian State University
Measurement Techniques | Year: 2011
The results of an experimental investigation of the convective heat transfer from a sphere to a temperature-stabilized gas flow for low values of the Reynolds number are presented. These results enable the following conclusion to be drawn: in the Nusselt number the radius of the sphere must be taken as the characteristic size and not the diameter, as is generally assumed. © 2011 Springer Science+Business Media, Inc.