Kannur Medical College

Cannanore, India

Kannur Medical College

Cannanore, India
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Kahkashan A.,Kannur Medical College | Ismail I.M.,Kannur Medical College
National Journal of Physiology, Pharmacy and Pharmacology | Year: 2017

Background: Non-communicable diseases such as hypertension, diabetes, and cancer have replaced communicable diseases as the leading cause of mortality in most parts of the world including India. Hypertension is a major public health problem in India which often results in coronary artery disease and stroke. As tribal populations are relatively isolated from the modern lifestyle, it is often hypothesized that their blood pressure is lower than the general population. Aims and Objectives: This study aims to describe the normal pattern of blood pressure and to assess the prevalence and associated factors of hypertension among a selected tribal population of Kerala. Materials and Methods: The study was carried out among tribal settlements of Kannavam Area, Kannur District, Kerala. Using convenient sampling method, 300 individuals aged 18 years and above were selected. Pregnant women and those individuals who were not willing to participate were excluded from the study. Data on sociodemographic variables, physical activity, tobacco consumption, and alcohol intake were collected. Blood pressure was recorded and classified according to Joint National Committee - 8 criteria. Data entry and analysis was done on SPSS version 17. Results: The mean systolic and diastolic blood pressure was found to be 125.2 mmHg and 77.1 mmHg, respectively. Only 45.7% of the study individuals had normal blood pressure, and the rest had either hypertension or pre-hypertension. Increasing age, alcohol intake, sedentary lifestyle, obesity, and central obesity were found to be significant factors responsible for high blood pressure. Conclusion: The tribal population’s mean systolic and diastolic blood pressure was similar to those of rural population of Kerala. A large proportion of the population had elevated blood pressure especially the elderly, thus necessitating annual screening in them. Alcohol intake and obesity were found to be associated with hypertension; hence, health education on harmful effects of alcohol and benefits of a balanced diet should be given to the tribal population. © 2017 Azeez Kahkashan and Imaad Mohammed Ismail.

Kamakshi G.,Kannur Dental College | Yaranal P.J.,Kannur Medical College
Journal of Clinical and Diagnostic Research | Year: 2014

A chondrolipoma is an extremely rare form of a benign mesenchymal tumour which contains mature fatty tissue and cartilage. We are presenting a case of chondrolipoma of the lower lip which was seen in a 6-year-old girl. Chondrolipomas are rare neoplasms; their terminologies and pathogeneses have been controversial in the past. Chondrolipomas are uncommonly seen in the oral cavity, in children and in females. Hence, we are reporting this present case because rarity of this lesion.

Yaranal P.J.,Kannur Medical College | Harish S.G.,Basaveshwar Medical College | Purushotham B.,Pariyaram Medical College
Indian Journal of Cancer | Year: 2014

Introduction: Primary intestinal lymphoma (PIL) is defined as an extranodal lymphoma arising in the intestine. This study includes 11 PILs. Objectives: The objective of this study was to evaluate the clinicopathological characteristics of primary non-Hodgkin′s lymphoma (NHL) in the small and large intestine. All cases were reclassified according to the World Health Organization classification of lymphoma in 2001. Immunohistochemistry (IHC) was used to confirm the histopathological diagnosis. Materials and Methods: Eleven cases of primary non-Hodgkin in the small and large intestine were studied retrospectively in a 5 year period. There were seven cases of resected intestinal specimens and four biopsy specimens. Five cases from ileum and two cases each from caecum and duodenum and one case each from jejunum and duodenum. Hematoxylin and eosin stained sections were studied with light microscopy and IHC for CD5, 20, 21 and cyclin D1 were done. Results: It is a retrospective study of 11 cases of intestinal lymphomas. Abdominal pain and abdominal lump were two main common presenting symptoms. NHLs were more common in the small intestine. PILs are common in adults (75% above 46 years) with male preponderance. All were NHLs and B-cell type. Five cases were diffuse large B-cell lymphoma and four cases each were mucosa-associated lymphatic tissue lymphoma and follicular lymphoma. One case was lymphomatoid polyposis or mantle cell lymphoma. Conclusion: PILs is rare and differs significantly from their gastric counterpart, not only in pathology but also with regard to clinical features, management and prognosis. Due to the lack of characteristic symptoms and a low incidence rate, PIL is misdiagnosed until serious complications occur, such as perforation and bleeding and hence needs to be accurately diagnosed.

Kunhimangalam R.,National Institute of Technology Calicut | Ovallath S.,Kannur Medical College | Joseph P.K.,National Institute of Technology Calicut
Journal of Medical Systems | Year: 2014

The prevalence of peripheral neuropathy in general population is ever increasing. The diagnosis and classification of peripheral neuropathies is often difficult as it involves careful clinical and electro-diagnostic examination by an expert neurologist. In developing countries a large percentage of the disease remains undiagnosed due to lack of adequate number of experts. In this study a novel clinical decision support system has been developed using a fuzzy expert system. The study was done to provide a solution to the demand of systems that can improve health care by accurate diagnosis in limited time, in the absence of specialists. It employs a graphical user interface and a fuzzy logic controller with rule viewer for identification of the type of peripheral neuropathy. An integrated medical records database is also developed for the storage and retrieval of the data. The system consists of 24 input fields, which includes the clinical values of the diagnostic test and the clinical symptoms. The output field is the disease diagnosis, whether it is Motor (Demyelinating/Axonopathy) neuropathy, sensory (Demyelinating/Axonopathy) neuropathy, mixed type or a normal case. The results obtained were compared with the expert's opinion and the system showed 93.27% accuracy. The study aims at showing that Fuzzy Expert Systems may prove useful in providing diagnostic and predictive medical opinions. It enables the clinicians to arrive at a better diagnosis as it keeps the expert knowledge in an intelligent system to be used efficiently and effectively. © Springer Science+Business Media 2014.

Kunhimangalam R.,National Institute of Technology Calicut | Ovallath S.,Kannur Medical College | Joseph P.K.,National Institute of Technology Calicut
Journal of Mechanics in Medicine and Biology | Year: 2012

The recent years have witnessed an increase in the use of newer analytical tools in the field of medicine to assist in diagnostic procedure. Among the new tools, artificial neural networks (ANNs) have received particular attention because of their ability to analyze complex nonlinear data sets. This study suggests that ANNs can be used for the diagnosis of peripheral nerve disorders particularly the carpal tunnel syndrome (CTS) and neuropathy. This paper aims at building a classifier using a feed forward neural network that can distinguish between CTS, neuropathy, and normal controls using a reduced set of measurements or features from nerve conduction study (NCS) data. Three different ANN training algorithms, viz. LevenbergMarquardt (LM), Conjugate gradient (CGB), and resilient back-propagation (RP) are used to see which algorithm produces better results and has faster training for the application under consideration. The data used were obtained from the Neurology Department, Kannur Medical College, Kerala, India. The obtained resultant confusion matrix indicated only a few misclassifications in all the three cases. The analysis showed that the CGB and RB algorithms provide faster convergence on pattern recognition problems, but the best performance in terms of accuracy is given by the LM algorithm. The accuracy obtained for the LM, CGB, and RB were 98.3%, 97.8%, and 97.2%, respectively. The respective sensitivities were 96.1%, 94.1%, and 94.1%, while the specificities were found to be equal to 99.4%, 98.8%, and 97.5%, respectively. The study aims at showing that ANNs may prove useful in combination with other systems in providing diagnostic and predictive medical opinions. However, it must always be kept in mind that ANNs represent only one form of computer-aided diagnosis, and the clinician's responsibility and overall control of patient care should never be underestimated. © 2012 World Scientific Publishing Company.

Kunhimangalam R.,National Institute of Technology Calicut | Ovallath S.,Kannur Medical College | Joseph P.K.,National Institute of Technology Calicut
IRBM | Year: 2013

Aim The aim was to design and develop a decision support system with a graphical user interface for the prediction of the case of peripheral nerve disorder and to build a classifier using artificial neural networks that can distinguish between carpal tunnel syndrome, neuropathy and normal peripheral nerve conduction. Materials and methods The data used were the Nerve Conduction Study data obtained from Kannur Medical College, India. A recurrent neural network and a two-layer feed forward network trained with scaled conjugate gradient back-propagation algorithm were implemented and results were compared. Results Both the networks provided fast convergence and good performance, accuracy being 98.6% and 97.4% for the recurrent neural network and the feed forward networks respectively, the confusion matrix in each case indicated only a few misclassifications. The developed decision support system also gave accurate results in agreement with the specialist's diagnosis and was also useful in storing and viewing the results. Discussions In the field of medicine, programs are being developed that aids in diagnostic decision making by emulating human intelligence such as logical thinking, decision making, learning, etc. The system developed proves useful in combination with other systems in providing diagnostic and predictive medical opinions. It was not meant to replace the specialist, yet it can be used to assist a general practitioner or specialist in diagnosing and predicting patient's condition. Conclusions The study proves that artificial neural networks are indeed of value in combination with other systems in providing diagnostic and predictive medical opinions. But the major drawback of these studies, which makes use of the nerve conduction study data are the inherent shortcomings of the interpretation of the results, which include lack of standardization and absence of population-based reference intervals. © 2013 Elsevier Masson SAS.

Yaranal P.J.,Kannur Medical College | Hegde V.,Kannur Medical College
Journal of Clinical and Diagnostic Research | Year: 2013

Salpingitis isthmica nodosa places the patient at risk for recurrent ectopic pregnancy or infertility. Hence, we report a case of salpingitis isthmica nodosa which was salpingectomized for pain abdomen in a 46- year old woman.

Hegde V.K.,Kannur Medical College | Khadilkar U.N.,Kasturba Medical College
Indian Journal of Pathology and Microbiology | Year: 2014

Background: Interface dermatitis (ID) refers to a pattern of skin reaction characterized by an inflammatory infiltrate that appears to obscure the dermo-epidermal junction when observed at low power examination and referred to as lichenoid tissue reaction. A wide range of inflammatory skin diseases exhibits interface change with considerable overlap of histological features. The aim of the present study was to study the clinical features and microscopic features of ID. Materials and Methods: The material for the present study consisted of skin biopsy samples collected from patients attending the outpatient Department of Dermatology. The study was conducted for a period of 3 years from 2007 to 2010. During this period, a total of 125 cases was studied. Results: In the present study, a total of 125 cases of ID was studied which presented clinically as papulosquamous disorders. Majority of the cases of ID were seen in women (57.6%). Majority of ID were lichen planus (LP) and its variants (63.2%). Clinicopathological concordance was seen in 109 cases (87.2%) and discordance in 16 cases (12.8%). Conclusion: The mere presence of an interface lichenoid inflammatory reaction should not be the sole criterion for the diagnosis of LP or one of its many variants, as now seems to be the case. A clinicopathologic correlation is absolutely essential for a conclusive diagnosis of ID.

PubMed | Jawaharlal Institute of Postgraduate Medical Education & Research, Kannur Medical College and ESI Postgraduate Medical Education and Research
Type: Journal Article | Journal: European journal of orthopaedic surgery & traumatology : orthopedie traumatologie | Year: 2016

The study was conducted to evaluate clinical and microbiological profile of neonates with septic arthritis and also to assess changing epidemiology in the microbial etiology.Twenty-nine neonates (1-28days of life) presenting to the Department of Orthopaedics with acute septic arthritis were included in the study. This was a descriptive study, and the data were collected during the time of hospital admission. History and clinical examination of the neonates were taken, and diagnosis was made based on clinical and laboratory parameters. Emergency arthrotomy was performed to prevent catastrophic sequelae in all the cases given antibiotics as per the culture results.Female children predominated in our study. The children were brought to the OPD with an average of 2.7days of fever. Thirty-four joints were involved in 29 neonates, out of whom five had more than one joint involvement. Joint effusion or subperiosteal abscess was found in 22 patients by USG. All children had leukocytosis with neutrophilic predominance. Twenty-one of twenty-nine patients had hip-joint involvement followed by knee in seven patients. Gram-negative organisms had grown more commonly, among which Klebsiella pneumonia was grown in nine patients.Prematurity and anemia still appear to be important risk factors for neonatal septic arthritis. As there is changing trend toward gram-negative infections, attention has to be given toward preventing nosocomial and community-acquired infections. This is very important in premature infants who are susceptible for infection when they are kept in resuscitative units in hospitals.

PubMed | Kannur Medical College and Government Medical College
Type: | Journal: Indian heart journal | Year: 2016

A 52-year-old male with history of dilated cardiomyopathy was admitted with progressive dizziness and worsening dyspnea. His blood pressure was 100/60 with a regular pulse of 70 per minute. Jugular vein wave showed a prominent pulse like regular cannon waves. Cannon wave occurs in conditions with atrioventricular dissociation and right atrial contraction against a closed tricuspid valve. Large A waves are associated with reduced right ventricular compliance or elevated right ventricular end-diastolic pressure.

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