Kanchi Mamunivar Center for Post Graduate Studies Autonomous

Puducherry, India

Kanchi Mamunivar Center for Post Graduate Studies Autonomous

Puducherry, India

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Petrus A.J.A.,Kanchi Mamunivar Center for Post Graduate Studies Autonomous | Bhuvaneshwari N.,Kanchi Mamunivar Center for Post Graduate Studies Autonomous | Alain J.A.L.,Shasun Research Center
Indian Journal of Natural Products and Resources | Year: 2011

Indigenous leafy vegetables of the traditional rural communities are potentially nutritious and contain a vast array of beneficial phytochemicals that offer protection against several chronic and age-related human ailments. The present study was planned to assess the antioxidative constitution of the fresh leaves of Mukia maderaspatana (Linn.) M. Roem. (Family: Cucurbitaceae). The total phenolic, flavonoid, carotenoid and vitamin E contents were determined using specific spectrophotometric methods and the amount of ascorbic acid by titrimetry. The medicinal leafy vegetable was found to be a good dietary source of the low molecular weight antioxidants analysed. The leaf extract exhibited potent in vitro antioxidant/radical scavenging (ABTS•+ and FRAP assays) and metal (Ferrous ion) chelating activities and also inhibited β-carotene bleaching. Saponarin has been isolated and determined as the major phenolic antioxidant by HPLC. The amount of phenolics (292.392 ±1.087 mg GAE), flavonoid (247.079 ± 0.705 QE), carotenoids (0.812 ± 0.075 mg), vitamins C (17.046 ± 0.839 mg) and E (0.194 ± 0.068 mg) and saponarin (220.800 ± 0.944 mg) present and the antioxidant capacities (301.926 ± 0.869 mg vitamin C equivalent antioxidant capacity) are reported for 100 g of fresh leaves. The protective/therapeutic significance of these antioxidant components is also highlighted.


Petrus A.J.A.,Kanchi Mamunivar Center for Post Graduate Studies Autonomous
Indian Journal of Natural Products and Resources | Year: 2013

Mukia maderaspatana (L.) M. Roem. (Family-Cucurbitaceae) [syn. Melothria maderaspatana (L.) Cogn.] grows common in village hedges and other open habitats and in the disturbed sites of the semi-evergreen and deciduous forests. It is distributed throughout the tropics and subtropics of the Old World, where different parts of the plant are being utilized for the health-care needs of human beings and livestock. The leaves and tender shoots are also frequently consumed as a part of the South Indian cuisine. Preclinical animal experiments have substantiated a number of traditional and folkloric medicinal claims, including hypotensive, hypolipidemic, hepatoprotective, hypoglycaemic, immunomodulatory, antimicrobial, antiplatelet-aggregation, antiulcer, anxiolytic and local anaesthetic characteristics of the plant extracts. Encouraging results have emerged from clinical investigations also as a chemoprotective plant in subjects suffering from hypertension, diabetes, dyslipidemia and rheumatoid arthritis. The present review aims to offer a concise pioneering account of (i) the ethnomedical uses of the leaves, tender shoots, stem, fruits and roots of the drug-plant among various traditional communities inhabiting different parts of the world, (ii) the motivating outcome of the preclinical and clinical investigations of the plant extracts and (iii) progress attained in the techniques of propagation of this potentially useful indigenous functional food plant which is currently tending to transform as an endangered taxon.


Petrus A.J.A.,Kanchi Mamunivar Center for Post Graduate Studies Autonomous
Asian Journal of Chemistry | Year: 2011

Mistletoes are being used in the treatment and management of a number of diseases, both in the traditional and in the complementary medicines, in several cultures. Fresh aerial parts of the obligate epiparasite, Viscum capitellatum Sm., hyperparasiting on the mistletoe Dendrophthoe falcata, a parasite on the terrestrial host, Albizzia lebbeck, was found to possess in vitro antioxidant capacity, as determined by the ABTS•+ and NO scavenging, FRAP and ?-carotene bleaching assays and capable of potentially chelating ferrous ions. Terpenes (lupeol and betulin), terpenic acids (betulinic and oleanolic acids), sterols (spinasterol and β-sitosterol) and carotenoids have been identified as the antioxidant metabolites of the lipophilic fraction and phenolic acids (chlorogenic acid, caffeic acid and p-coumaric acid), 7-hydroxy-3,5,6,3',4'-pentamethoxyflavone, eriodictyol and its 7-O-β-D-glucopyranoside as the predominant antioxidant phytoconstituents of the hydrophilic fractions of the mistletoe extract.


Petrus A.J.A.,Kanchi Mamunivar Center for Post Graduate Studies Autonomous
Asian Journal of Chemistry | Year: 2011

Cancer remains the second most abundant cause of death globally. Traditional herbal medicines possessing antioxidant potentials offer protection against several chronic and predominantly life-style oriented human diseases, including cancer. Mallotus stenanthus, which has been reported to be an anticancer agent against P388 lymphocytic leukaemia in mice, has been evaluated to possess in vitro antioxidant (ABTŜ+ scavenging, FRAP, β-carotene bleaching) capacities and metal chelating abilities. The antioxidant capacities correlated well with the phenolic and flavonoid constitutions. The EtOAc fraction exhibited highest antioxidant capacity, 7-O-β-D-glucopyranosides of diosmetin and chrysoeriol together with ellagic acid, phloroglucinol and its derivatives have been isolated and characterized, substantiating the reported antitumour properties of the leaf extract.


Petrus A.J.A.,Kanchi Mamunivar Center for Post Graduate Studies Autonomous
Asian Journal of Chemistry | Year: 2012

Mukia maderaspatana (Linn.) M. Roemer, (family : Cucurbitaceae) is a wild functional food plant, traditionally used for human consumption by various cultures. Indigenous communities around the world utilize various parts of the plant to alleviate a number of human and livestock ailments. For the first time, this review attempts to critically assess the global distribution and vernacular names as well as the phytochemical profile and the antioxidant capacity of this potentially medicinal taxon.


Palanisamy V.,Alagappa University | Annadurai P.,Kanchi Mamunivar Center for Post Graduate Studies Autonomous
International Journal of Internet Protocol Technology | Year: 2011

In wireless and distributed nature of ad hoc networks, security has become a more sophisticated problem than security in other networks, due to the open nature and the lack of infrastructure of such networks. TBCMKDS discussed in this paper addresses the key management issues encountered in ad hoc networks. TBCMKDS is inspired by the control, accessibility and scalability characteristic of cluster architecture in distributed systems. The system builds cluster and spans the entire network with different clusters. The nodes within the cluster select a cluster head using degree of neighbours, node identification and trust, mimicking the human neighbour enquiry model. After a detailed analysis on various existing key management schemes, the proposed scheme freezes with the modified version of web of trust approach. elliptic curve cryptography (ECC) is used for key pair and certificate generation, since ECC provides higher security with lesser key size. Copyright © 2011 Inderscience Enterprises Ltd.


Petrus A.J.A.,Kanchi Mamunivar Center for Post Graduate Studies Autonomous
Asian Journal of Chemistry | Year: 2014

Plants, in general and functional food plants particularly, have been analyzed to be the rich sources of numerous redox-active secondary metabolites. Phytophenols are undoubtedly the ubiquitous class of bioactive constituents of the human diet manifesting both nutritional and health benefits mediated largely by their redox property, reactive species-scavenging and metal chelating capacities and can mitigate oxidative stress-induced tissue damage associated with chronic diseases. Though the therapeutic potentials and the antioxidant/prooxidant capacities of the individual biophenols are themselves potential topics of debate, an ever-expanding quantum of scientific evidence does tend to support their protective role, via diet, against the presently mushrooming age-related degenerative disorders. The present review attempts to portray the status quo of dietary biophenols in the health and longevity.


Petrus A.J.A.,Kanchi Mamunivar Center for Post Graduate Studies Autonomous | Kalpana K.,Kanchi Mamunivar Center for Post Graduate Studies Autonomous | Devi A.B.,Kanchi Mamunivar Center for Post Graduate Studies Autonomous
Oriental Journal of Chemistry | Year: 2014

Alternanthera bettzickiana (Regel) Nicolson is an erect herb and an ornamental pot plant, which is recorded to be useful in purifying and nourishing blood. It is also claimed to be a soft laxative, a galactagogue and an antipyretic in addition to its wound healing property. The leaves are reported to be used like spinach and in soups. The lipophilic acetone extract of the fresh flowers exhibited in vitro antioxidant/radical scavenging (ABTS &Z.ast;+ and FRAP assays) and metal (Ferrous ion) chelating capacities. The extract has been analysed to contain eighteen saturated and four unsaturated hydrocarbons, ten saturated, three monounsaturated and one polyunsaturated esters of fatty acid, in addition to a saturated and an unsaturated higher alcohol and a fatty aldehyde, together with a monoterpene and nine acyclic diterpenes and a steroid. γ -Tocopherol and α- tocopherol- β -D-mannoside are the principal vitamin E identified in combination with pairs of cyclohexenones and benzofuranones as well as five phthalates.


Petrus A.J.A.,Kanchi Mamunivar Center for Post Graduate Studies Autonomous
Oriental Journal of Chemistry | Year: 2014

Phylogenetic relationships in the order Cucurbitales as well as the phytogeny and classification of its taxonomically most problematic family, Cucurbitaceae, have been the focus of several studies. Taxonomists over the years have differed on the delimitation of Cucumis L. and numerous taxonomie treatments have been proposed since the pioneering work of Linnaeus (1753). Using maximum parsimony, maximum likelihood, and Bayesian inference analyses of sequence data from the nuclear and chloroplast genomes, the genus Cucumis has recently been recircumscribed. Among the various chemical classes elaborated in plants, the foliar phenolics express greater stability in general and contribute significantly to the chemosystematics of both, angiosperms and gymnosperms. Hence, it is felt that an evaluation of the available literature on the foliar flavonoid constitution of the recently defined Cucumis would be relevant. This paper, therefore, analyses the distribution of the phytophenols in the taxa to ascertain the characteristically common foliar marker biochemical of the genus in addition to an attempt to justify the inclusion of the genus Mukia within Cucumis.


Petrus A.J.A.,Kanchi Mamunivar Center for Post Graduate Studies Autonomous
Asian Journal of Chemistry | Year: 2013

Sauropus androgynus (L.) Merrill [Family: Phyllanthaceae Martynov] is a popular leafy-vegetable in South and Southeast Asia and is notable for its high yields and palatability. The leaves and succulent young tips of the plant are normally eaten like tropical asparagus, raw in the form of salads or steamed or alternatively added to stir-fry, rice and egg dishes, soups or casseroles, and sometimes blanched to serve with chilli paste. The rich vitamin content of the leaves has led to its popular name, 'multivitamin green' and has also been recorded as a tropical vegetable by the United States Department of Agriculture. The flowers and the small purplish fruits of the plant are also reported to be eaten. The present paper attempts to review the health-impact of the nutritive factors and other phytometabolites biosynthesized by this functional leafy-vegetable, in addition to its ethnomedical claims.

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