Ishikawa, Japan
Ishikawa, Japan

Kanazawa Medical University is a private university in Uchinada, Ishikawa, Japan, established in 1972. Wikipedia.


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Patent
Kanazawa Medical University and Shinko Chemical Co. | Date: 2016-06-15

The present invention relates to a culture vessel which can be broadly applied to culture, regeneration, manufacture, observation and the like of targets such as cells, organs, and microorganisms. In the culture vessel of the present invention, a first vessel 10 and a second vessel 20 each being a closed-bottom, open-top vessel are provided. In the first vessel 10 and the second vessel 20, a sideways-facing opening 12 and a sideways-facing opening 22 are formed. The opening 12 and the opening 22 communicate in a watertight manner when the openings 12, 22 are connected face to face.


Patent
Kanazawa Medical University and Shinko Chemical Co. | Date: 2014-07-31

The present invention relates to a culture vessel which can be broadly applied to culture, regeneration, manufactures observation and the like of targets such as cells, organs, and microorganisms. In the culture vessel of the present invention, a first vessel 10 and a second vessel 20 each being a close-bottom, open-top vessel are provided. In the first vessel 10 and the second vessel 20, a sideways-facing opening 12 and a sideways-facing opening 22 are formed. The opening 12 and the opening 22 communicate in a watertight manner when the openings 12, 22 are connected face to face.


Patent
Kanazawa Medical University, Kanazawa Institute of Technology and Tokai Medical Products Inc. | Date: 2013-03-08

A manufacturing method of a heart correction net includes: a first step of taking cross-sectional images of a heart in a layer direction, in which an apex and a base of the heart are connected; a second step of extracting outlines of the heart from the cross-sectional images; a third step of defining dividing points with respect to a three-dimensional shape reconstructed based on the outlines, the dividing points being defined on the outlines in a circumferential direction of the heart; a fourth step of dividing a contour of the heart in three-dimensions into divided regions based on the plurality of the dividing points, and creating development data, in which the each of the divided regions is developed on a two-dimensional plane; a fifth step of creating paper-pattern data based on the development data; and a sixth step of knitting the heart correction net based on the paper-pattern data.


Patent
Kanazawa Medical University, Kanazawa Institute of Technology and Tokai Medical Products Inc. | Date: 2015-01-28

A manufacturing method of a heart correction net is provided. The method includes: a first step of taking cross-sectional images of a heart in a layer direction, in which an apex and a base of the heart are connected; a second step of extracting outlines of the heart from the cross-sectional images; a third step of defining dividing points with respect to a three-dimensional shape reconstructed based on the outlines, the dividing points being defined on the outlines in a circumferential direction of the heart; a fourth step of dividing a contour of the heart in three-dimensions into divided regions based on the plurality of the dividing points, and creating development data, in which the each of the divided regions is developed on a two-dimensional plane, while an approximate shape of each of the divided regions is maintained; a fifth step of creating paper-pattern data based on the development data; and a sixth step of knitting the heart correction net with a knitting machine based on the paper-pattern data.


Patent
Kanazawa Medical University and Kanazawa Institute of Technology | Date: 2015-01-14

A heart correction net according to the present invention is attached to an exterior of a heart. The heart correction net includes a first area that is a partial area included in a right ventricle side area of an entire area surrounding exteriors of ventricles; and a second area that is an area surrounding the first area in the right ventricle side area and a left ventricle side area. The first area in the heart correction net is configured to provide a lower contact pressure against a heart during a cardiac diastole than the second area.


Ueda Y.,Kanazawa Medical University
Molecular Neurobiology | Year: 2014

Since the discovery of phosphatidylinositol-3-kinase, scientific interest in the biological functions of phosphoinositides has greatly increased. Currently, seven phosphoinositides have been identified. These phosphoinositides are specifically localized to organelle membranes, their site of action. Phosphoinositides can regulate neuronal function by specifically recruiting downstream proteins that have phosphoinositide-binding domains. To date, it is well accepted that phosphoinositides play important roles in a broad spectrum of neuronal functions from regulating neural development to modulating synapse function. This review will provide an overview of the function and distribution of phosphoinositides at synapses. © 2014, Springer Science+Business Media New York.


A method and a kit are provided to produce a biological clear specimen within a short time and with a wide variety of biological specimens. The method includes the following steps: (1) treating a material to be cleared with an aqueous fixing solution containing paraformaldehyde or the like, a nonionic surfactant, an alkali, and optionally a buffering agent; (2) treating the material from step (1) or a conventionally fixed material with an aqueous clearing accelerator solution containing a nonionic surfactant and an alkali; and (3) treating the material produced in step (1) or (2) with an aqueous preservation solution containing a nonionic surfactant and a polyhydric alcohol. In each of the steps, the nonionic surfactant is present at a concentration of 1% or more. The kit includes solutions used in each of the steps of the method.


Provided are: a method and a kit for producing a biological specimen clear, which enable the clearing within a short time and by which a wide variety of biological specimens can be cleared; and a method and a kit for preserving a cleared biological specimen. A method for producing a cleared biological specimen, comprising steps as mentioned in items (A) to (C). (A) Step (1) of treating a material to be cleared with a fixing solution that is an aqueous solution containing paraformaldehyde or the like, a nonionic surfactant (at a concentration of 1% or more) and an alkali and optionally containing a buffering agent to produce the material that is cleared is involved. (B) Step (2) of treating the material that is produced in step (1) or a material to be cleared which is produced by a conventional fixing method with a clearing accelerator solution that is an aqueous solution containing a nonionic surfactant (at a concentration of 1% or more) and an alkali to produce the material that is cleared is involved. (C) Step (3) of treating the material produced in step (1) or (2) with a preservation solution that is an aqueous solution containing a nonionic surfactant (at a concentration of 1% or more) and a polyhydric alcohol to produce the material that is cleared is involved. A kit which can be used in the method.


Patent
Kanazawa Medical University | Date: 2016-02-03

Provided is a factor capable of inducing enucleation, which is a final stage of erythrocyte differentiation, within a short time. More particularly, provided are a method of inducing enucleation, which is a final stage of erythrocyte differentiation, within a short time by adding a compound derived from proopiomelanocortin (POMC) to an undifferentiated (nucleated) erythrocyte, and an enucleation inducer including the compound.


In a light irradiation device 20 for improving cognitive symptom and depression symptom according to the present invention, photostimulation is given to a retina by continuous flashing of a light source 21 of frequency of 1 to 10 Hz, Homer 1a is made to continuously express by the photostimulation, and BK-type potassium channel in pyramidal cell of cerebral cortex is activated. It is possible to exert an effect equivalent to a depression symptom improving effect obtained by an electroconvusion stimulation device, an effect equivalent to a depression symptom improving effect and an effect equivalent to a cognitive symptom improving effect obtained by a transcranial magnetic stimulation device. It is possible to utilize these devices also in home environment as compared with an electroconvusion stimulation device and a transcranial magnetic stimulation device which are limited to treatment in clinical institutions as opposed to home environment.

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