Kanagawa University of Human Services

www.kuhs.ac.jp/
Yokosuka, Japan

Kanagawa University of Human Services is a public university at Yokosuka, Kanagawa Prefecture, Japan. The school was established in 2003, and specializes in human welfare studies. Wikipedia.

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Nakahara S.,Kanagawa University of Human Services | Tomio J.,University of Tokyo | Ichikawa M.,University of Tsukuba | Nakamura F.,University of Tokyo | And 4 more authors.
JAMA - Journal of the American Medical Association | Year: 2015

Importance Neurologically intact survival after out-of-hospital cardiac arrest (OHCA) has been increasing in Japan. However, associations between increased prehospital care, including bystander Interventions and increases in survival, have not been well estimated. Objective To estimate the associations between bystander Interventions and changes in neurologically intact survival among patients with OHCA in Japan. Design, Setting, and Participants Retrospective descriptive study using data from Japan's nationwide OHCA registry, which started in January 2005. The registry includes all patients with OHCA transported to the hospital by emergency medical services (EMS) and recorded patients' characteristics, prehospital Interventions, and Outcomes. Participants were 167 912 patients with bystander-witnessed OHCA of presumed cardiac origin in the registry between January 2005 and December 2012. EXPOSURES Prehospital Interventions by bystander, including defibrillation using public-access automated external defibrillators and chest compression. Main Outcomes and Measures Neurologically intact survivalwas defined as Glasgow-Pittsburgh cerebral performance category score 1 or 2 and overall performance category scores 1 or 2 at 1 month or at discharge. The association between the Interventions and neurologically intact survival was evaluated. RESULTS From 2005 to 2012, the number of bystander-witnessed OHCAs of presumed cardiac origin increased from 17 882 (14.0 per 100 000 persons [95%CI, 13.8-14.2]) to 23 797 (18.7 per 100 000 persons [95%CI, 18.4-18.9]), and neurologically intact survival increased from 587 cases (age-adjusted proportion, 3.3%[95%CI, 3.0%-3.5%]) to 1710 cases (8.2%[95%CI, 7.8%-8.6%]). The rates of bystander chest compression increased from 38.6%to 50.9%, bystander-only defibrillation increased from 0.1% to 2.3%, bystander defibrillation combined with EMS defibrillation increased from 0.1% to 1.4%, and EMS-only defibrillation decreased from 26.6%to 23.5%. Performance of bystander chest compression, compared with no bystander chest compression, was associated with increased neurologically intact survival (8.4%[6594 survivors/78 592 cases] vs 4.1% [3595 survivors/88 720 cases]; odds ratio [OR], 1.52 [95%CI, 1.45-1.60]). Compared with EMS-only defibrillation (15.0%[6445 survivors/42 916 cases]), bystander-only defibrillation (40.7% [931 survivors/2287 cases]) was associated with increased neurologically intact survival (OR, 2.24 [95%CI, 1.93-2.61]), as was combined bystander and EMS defibrillation (30.5%[444 survivors/1456 cases]; OR, 1.50 [95%CI, 1.31-1.71]), whereas no defibrillation (2.0% [2369 survivors/120 653 cases]) was associated with reduced survival (OR, 0.43 [95%CI, 0.39-0.48]). Conclusions and Relevance In Japan, between 2005 and 2012, the rates of bystander chest compression and bystander defibrillation increased and were associated with increased odds of neurologically intact survival. © 2015 American Medical Association. All rights reserved.


Kinoshita S.,Kanagawa University of Human Services | Miyashita M.,Tohoku University
American Journal of Hospice and Palliative Medicine | Year: 2013

The purpose of this study was to investigate the evaluation of end-of-life care from bereaved family of cancer patients who had died in intensive care units in Japan. Cross-sectional anonymous questionnaire surveys were conducted on community dwelling individuals aged 40-79 who were randomly sampled from census tracts. End-of-life care was assessed using the Good Death Inventory and Care Evaluation Scale. The respondents were 4011 bereaved family and response rate was 40%. Of 390 respondents had experienced bereavement in intensive care unit. Of 152 respondents had lost a loved one due to cancer. The result showed that bereaved family of cancer patients evaluated lower than the non-cancer patients for The doctors dealt promptly with discomforting symptoms of the patients' (p=0.009), 'The nurses had adequate knowledge and skills' (p=0.016), 'Admission (use) was possible when necessary without waiting' (p=0.008), Consideration was given to the health of the family (P=0.039) and Physical and psychological comfort (p=0.03). Overall, it can be presumed that the cancer patients' bereaved family evaluated about symptoms management and doctors and nurses skills was low. There is a need to improve for end-of-life care of cancer patients and to conduct further research to explore quality-improvement interventions to bereaved family of cancer in intensive care unit. © The Author(s) 2012.


Nakahara S.,Kanagawa University of Human Services | Ichikawa M.,University of Tsukuba | Nakajima Y.,Osaka Prefecture University
Traffic Injury Prevention | Year: 2015

Objectives: In Japan, child restraint use among preschool children started to increase before compulsory child restraint use for children aged 0–5 years was introduced by legislation in April 2000. This study determined the effects of increased child restraint use in reducing motor vehicle occupant injuries among children aged 0–5 years.Methods: We obtained monthly police data of child vehicle occupant injuries from 1990 to 2009. We calculated monthly ratios of morbidity rates per population of children aged 0–5 years to those of children aged 6–9 years. Time trends of the morbidity rate ratios were analyzed using a joinpoint regression model to determine whether there were trend changes in child occupant injuries and when they occurred if there were trend changes.Results: The morbidity rate ratios showed a slightly increasing trend of 0.03% per month (95% confidence interval [CI], −0.02% to 0.09%) until the change-point in December 1997 (95% CI, July 1996 to January 1999), which then changed to a decreasing trend of −0.14% per month (95% CI, −0.16 to −0.11), with an overall trend change of −0.17% (95% CI, −0.23 to −0.11). No change-point was identified in or around April 2000 when compulsory restraint use was introduced.Conclusions: The present study used comparative indicators relative to age groups that were not covered by the legislation and showed that a decreasing trend of occupant morbidity among children aged 0–5 years started before the introduction of compulsory restraint use. This change probably reflects the prelegislative voluntary increase in child restraint use. © 2015, Copyright © Taylor & Francis Group, LLC.


Kishita Y.,Tokyo Metroplitan University | Tsuda M.,Kanagawa University of Human Services | Aigaki T.,Tokyo Metroplitan University
Biochemical and Biophysical Research Communications | Year: 2012

Mitochondrial trifunctional protein (MTP), which consists of the MTPα and MTPβ subunits, catalyzes long-chain fatty acid β-oxidation. MTP deficiency in humans results in Reye-like syndrome. Here, we generated . Drosophila models of MTP deficiency by targeting two genes encoding . Drosophila homologs of human MTPα and MTPβ, respectively. Both . MtpαKO and . MtpβKO flies were viable, but demonstrated reduced lifespan, defective locomotor activity, and reduced fecundity represented by the number of eggs laid by the females. The phenotypes of . MtpαKO flies were generally more striking than those of . MtpβKO flies. . MtpαKO flies were hypersensitive to fasting, and retained lipid droplets in their fat body cells as in non-fasting conditions. The amount of triglyceride was also unchanged upon fasting in . MtpαKO flies, suggesting that lipid mobilization was disrupted. Finally, we showed that both . MtpαKO and . MtpβKO flies accumulated acylcarnitine and hydroxyacylcarnitine, diagnostic markers of MTP deficiencies in humans. Our results indicated that both . MtpαKO and . MtpβKO flies were impaired in long-chain fatty acid β-oxidation. These flies should be useful as a model system to investigate the molecular pathogenesis of MTP deficiency. © 2012 Elsevier Inc.


Sato-Miyata Y.,Tokyo Metroplitan University | Muramatsu K.,Tokyo Metroplitan University | Funakoshi M.,Tokyo Metroplitan University | Tsuda M.,Kanagawa University of Human Services | Aigaki T.,Tokyo Metroplitan University
Frontiers in Physiology | Year: 2014

Insulin/insulin-like growth factor (IGF) plays an important role as a systemic regulator of metabolism in multicellular organisms. Hyperinsulinemia, a high level of blood insulin, is often associated with impaired physiological conditions such as hypoglycemia, insulin resistance, and diabetes. However, due to the complex pathophysiology of hyperinsulinemia, the causative role of excess insulin/IGF signaling has remained elusive. To investigate the biological effects of a high level of insulin in metabolic homeostasis and physiology, we generated flies overexpressing Drosophila insulin-like peptide 2 (Dilp2), which has the highest potential of promoting tissue growth among the Ilp genes in Drosophila. In this model, a UAS-Dilp2 transgene was overexpressed under control of sd-Gal4 that drives expression predominantly in developing imaginal wing discs. Overexpression of Dilp2 caused semi-lethality, which was partially suppressed by mutations in the insulin receptor (InR) or Akt1, suggesting that dilp2-induced semi-lethality is mediated by the PI3K/Akt1 signaling. We found that dilp2-overexpressing flies exhibited intensive autophagy in fat body cells. Interestingly, the dilp2-induced autophagy as well as the semi-lethality was partially rescued by increasing the protein content relative to glucose in the media. Our results suggest that excess insulin/IGF signaling impairs the physiology of animals, which can be ameliorated by controlling the nutritional balance between proteins and carbohydrates, at least in flies. © 2014 Sato-Miyata, Muramatsu, Funakoshi, Tsuda and Aigaki.


Tsuda M.,Kanagawa University of Human Services | Aigaki T.,Tokyo Metroplitan University
Fly | Year: 2016

The Drosophila sex-peptide (SP) has been identified as a seminal fluid component that induces post-mating responses (PMRs) in the inseminated females, such as inhibition of remating and stimulation of egg-laying. SP has been thought to play a central role in sexual conflict and sexually antagonistic co-evolution. Most of the sequenced Drosophila genomes contain SP orthologs, but their functions have been poorly characterized. Recently, we have investigated cross-species activity of D. melanogaster SP by means of injection into virgin females of other species. Among 11 species examined, SP response was observed in 6 species belonging to the D. melanogaster species group only. These species females express SP receptor (SPR) in their oviducts at relatively high levels, which was visualized by using a GFP-tagged SP. Furthermore, females of this species group responded to their own SP orthologs. However, females of the species outside the group did not respond to their own SP orthologs, even though all of them were potent inducers of SP-response in D. melanogaster. Our results suggested that the SP/SPR-mediated PMR was established in the lineage of the D. melanogaster species group. © 2016 Taylor & Francis


Mizuno M.,Kanazawa University | Kinefuchi E.,Kanagawa University of Human Services | Kimura R.,Kanazawa University | Tsuda A.,Kanazawa University
Nursing Ethics | Year: 2013

This study explored the relationship between professional quality of life and emotion work and the major stress factors related to abortion care in Japanese obstetric and gynecological nurses and midwives. Between October 2011 and January 2012, questionnaires that included questions concerning eight stress factors, the Professional Quality of Life Scale, and the Japanese version of the Frankfurt Emotional Work Scale, were answered by 255 nurses and midwives working in abortion and childbirth services. Professional Quality of Life scores (compassion fatigue, compassion satisfaction, burnout) were significantly associated with stress factors and emotion work. Multiple regression analysis revealed that of all the evaluated variables, the Japanese version of the Frankfurt Emotional Work Scale score for negative emotions display was the most significant positive predictor of compassion fatigue and burnout. The stress factors "thinking that the aborted fetus deserved to live" and "difficulty in controlling emotions during abortion care" were associated with compassion fatigue. These findings indicate that providing abortion services is a highly distressing experience for nurses and midwives. © The Author(s) 2013.


Ichikawa M.,University of Tsukuba | Nakahara S.,Kanagawa University of Human Services | Inada H.,University of Tsukuba
Accident Analysis and Prevention | Year: 2015

In Japan, a driving lesson consisting of a lecture, a driver aptitude test, on-road driving assessment and a discussion session was added to the driving license renewal procedure for drivers aged 75 years or older in 1998 and for drivers aged 70 years or older in 2002. We investigated whether these additions contributed to a reduction in at-fault motor vehicle collisions (MVCs) by examining the trend of the at-fault MVC rates per licensed driver and the rate ratios of the older drivers relative to those aged 65-69 years for the years 1986-2011. All data were derived from nationwide traffic statistics. If the introduction of the lesson was effective in reducing at-fault MVCs of older drivers, the rate ratio should have declined, given that the lesson targeted only the older drivers. We found this was not the case, i.e., there was no declining trend in the at-fault MVC rate ratios of both drivers aged 75 years or older and drivers aged 70 years or older, relative to drivers aged 65-69 years, after the driving lesson at license renewal became mandatory for these older drivers. Therefore, the mandatory lesson for the older drivers at license renewal needs to be reconsidered. © 2014 Elsevier Ltd. All rights reserved.


Nakamura T.,Kanagawa University of Human Services
Asia Pacific Journal of Clinical Nutrition | Year: 2011

The national government settled on "Healthy Japan 21" as the premier preventive policy of lifestyle related diseases in 2000. In 2005, the effectiveness of the campaign was conducted, but the results did not turn out as expected. The Ministry of Health, Labor and Welfare made the "Japanese Food Guide Spinning Top (JFG-ST)" as a practical and easy way to improve eating habits for all of the people. The JFG-ST falls down when the balance of the diets worsens and expresses a stable thing in what a turn (exercise) does. Eyes down quantity to take out of each group per day is shown in the basic form by the 5 distinction from grain dishes, vegetable dishes, fish and meat dishes, milk, and fruits. In 2005, the Basic Law on Dietary Education was enacted to promote the dietary education about the importance of eating proper meals in order to solve problems such as inappropriate eating habits and nutrition intake, disturbances in diets, increases in lifestyle-related diseases, a fall in the rate of food self-sufficiency and so forth. The Ministry of Education and Science started a program to train people to become "diet and nutrition teacher" in primary school. JFG- ST is developed in a dietary education campaign as a standard method of the dietary education. In May, 2011, the government has announced the second dietary education promotional basic plan to assume five years.


TOKYO--(BUSINESS WIRE)--The Rice Stable Supply Support Organization, a public interest incorporated association, held a media reception on February 16th entitled “The Appeal of Wachoshoku” (Japanese breakfasts). The event had the objective of increasing awareness of rice in meals and was aimed at tourists from abroad. The number of overseas visitors to Japan surpassed 24 million last year and continues to reach record highs every year, with the latest figures showing nearly 2.3 million people visiting in January alone (up 24% in the same period from the previous year). Since 2014, the Rice Stable Supply Support Organization has held annual events for non-Japanese media to promote Japanese cuisine (known as washoku), along with the foundational staple of washoku, which is rice. This year’s theme focused on traditional Japanese breakfasts, which incorporate national culture and a rich history, and gave foreign tourists from many countries the opportunity to experience a Japanese breakfast – wachoshoku. The event attracted attendees from 8 countries – including Australia, China, the Philippines, the UK and the USA - from various international media as well as Japanese food related media. At the reception, Kanagawa University of Human Services University President Professor Teiji Nakamura addressed the audience with his professional point of view on nutrition on why Japanese breakfasts are superior for healthy longevity. He commented that, “Even with the diversification of the Japanese diet, it is the fact that Japanese rice has remained on the dining room table that has given Japanese people healthy longevity”. After that, Tokyo’s number one international magazine, Metropolis, which has been running for over 20 years and provides the latest information to foreign residents, shared the results of a recent survey they held on recommended wachoshoku at hotels and ryokan (Japanese inns) throughout Japan. Lastly Hotel Okura Tokyo’s Yamazato restaurant conducted a short seminar on Japanese food etiquette, while guests were served a wachoshoku breakfast set consisting of rice as the main dish, along with miso soup, grilled fish and a number of side dishes. One attendee from an international media outlet remarked that although they felt they knew a lot about Japanese cuisine - washoku - in general, they didn’t know much about wachoshoku and this gave them a deeper understanding and they found it interesting with the knowledge of the culture being reflected in the meal. Another commented that they learnt a lot about the details of the nutritional information in the meal and felt they learnt more about the health advantages of wachoshoku. Results of an opinion poll conducted by Japan’s most influential English-language magazine aimed at tourists and foreign residents in Japan. "Recommended wachoshoku at hotels and ryokan by tourists and foreign residents in Japan" * Selection was based on responses from survey participants as well as Metropolis staff writers

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