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Sheikh N.A.,Kamineni Institute of Medical science
Indian Journal of Forensic Medicine and Toxicology | Year: 2012

Hospitals' committed to patient care and community healths have been cited to paradoxically defy their own objectives. On one hand they cure patients and on the other, have emerged as a source of several diseases. The Hospital waste is of special kind of waste. By the nature of its origin, hospital waste can become a health hazard and in extreme cases a source of epidemic. In order to provide for better management of hospital waste the Bio-medical (Handling and Management) Rules, 1998 was notified under the Environment Protection Act, 1986. The problem of hospital waste is more of quality as compared to quantity. It has been computed by the WHO that the average waste generated by hospitals in developed countries is in the range of 1-5 kg/bed/day, in comparison, the average for developing countries is between 1 to 2 kg/bed/day. This calls for coordination between all hospital departments that generate waste and agencies employed for the segregation, collection, transportation, treatment and disposal of waste. Source


Banji D.,P.A. College | Banji O.J.F.,P.A. College | Abbagoni S.,P.A. College | Hayath M.S.,Kamineni Institute of Medical science | And 2 more authors.
Brain Research | Year: 2011

Exposure to toxicants prenatally and postnatally could have deleterious consequences on the offspring. Postnatal exposure to valproate in mice pups is capable of inducing experimental autism resulting in neurobehavioral aberrations. Consumption of green tea has been associated with neuronal protection against the impact of toxicants. We investigated the role of green tea extract in reversing cardinal behavioral changes and aberrations in oxidative stress induced by valproate exposure. Young mice of both genders received a single dose of valproate (400 mg/kg subcutaneously) on postnatal day 14 followed by a daily dose of green tea extract (75 and 300 mg/kg) orally up to postnatal day 40. Mice pups were subjected to behavioral testing to assess motor co-ordination, nociceptive response, locomotion, anxiety, exploratory activity and cognition on various postnatal days up to postnatal day 40. At the end of behavioral testing, blood was withdrawn from the retro orbital plexus for the estimation of lipid peroxides. Animals were sacrificed on postnatal day 41 and whole brain was subjected to histopathological examination. Our studies revealed a significant improvement in behavioral assessments particularly with 300 mg/kg of green tea extract. Formation of markers of oxidative stress was reduced at both dose levels. Histological findings confirm the neuroprotective effect of green tea at a dose of 300 mg/kg. In conclusion it can be stated that green tea exerts neuronal cytoprotective action possibly due to anti-oxidant action and could be efficacious in the management of autism. © 2011 Elsevier B.V. All rights reserved. Source


Nirgude A.S.,Kamineni Institute of Medical science
Indian journal of public health | Year: 2010

Fluorosis is an important public health problem in certain parts of India. Nalgonda is one of the fluorosis endemic districts of Andhra Pradesh. A cross-sectional study was undertaken to assess the prevalence of dental and skeletal fluorosis in Panagal, one of the urban slum areas of Nalgonda town of Andhra Pradesh. 265 individuals residing in 92 households of five colonies of Panagal were selected by multi-stage random sampling. Fluorosis was assessed by standard clinical methods and water samples were tested for fluoride level. It was observed that mean fluoride level in ground water samples in the area was 4.01 mg/l and that of Nagarjunsagar water was 0.74 mg/l. The mean age of the study subjects in the area was 34.73 years. The overall prevalence of skeletal fluorosis was 24.9% and that of dental fluorosis was 30.6%. The prevalence increased with age. Skeletal and dental fluorosis is endemic in the study area. Source


Satti S.B.R.,O o Community Health Center | Kondagunta N.,Kamineni Institute of Medical science
Indian Journal of Community Medicine | Year: 2016

Background: The therapeutic regimens as recommended by the Revised National TB Control Programme (RNTCP) have been shown to be highly effective for both preventing and treating tuberculosis, but poor adherence to medication is a major barrier to its global control. Aim and Objectives: The study was conducted to assess the influence of patient related factors for DOTS Treatment Default among HIV-TB Co-infected cases. Setting and Design: This was a case control study conducted in Nalgond, Telangana. Materials and Methods: All new HIV-TB coinfected and DOTS-defaulted patients registered under RNTCP for the period from January 2010 to December 2012 were selected. Of the 154 patients, 23 had died and 11 could not be traced, and these were excluded. Thus the total number of available cases were 120 for those age- and sex-matched controls (HIV-TB coinfected patients and those who had completed the DOTS regimen successfully) were selected. Results: The mean age was 36.5 ± 9 years; the majority (23.3%) of patients defaulted during the second month of treatment. Significant risk factors associated with defaulting included unskilled occupation [adjusted odds ratio (AOR: 3.56; 95% confidence interval (CI): 1.1-11.56], lower middle class socioeconomic status (AOR: 17.16; 95% CI: 3.93-74.82), small family size (AOR: 21.3; 95% CI: 6.4-70.91), marital disharmony (AOR: 6.78; 95% CI: 1.93-23.76), not being satisfied with the conduct of health personnel (AOR: 7.38; 95% CI: 2.32-23.39), smoking (AOR: 8.5; 95% CI: 2.31-31.21), and side effects of drugs (AOR: 4.18; 95% CI: 1.35-12.9). Conclusion: Unskilled occupation, marital disharmony, small family size, lower middle class socioeconomic status, not being satisfied with the conduct of health personnel, smoking, and drug side effects were significantly associated with defaulting. Information on the pattern of tuberculosis (TB), the outcome of anti-tuberculosis treatment (ATT), and the factors associated with it will help in planning interventions to improve adherence to DOTS treatment. © 2016 Indian Journal of Community Medicine | Published by Wolters Kluwer - Medknow. Source


Sujatha V.V.,Kamineni Institute of Medical science
Tropical Doctor | Year: 2012

We present two cases of retained intrauterine contraceptive devices (IUCDs).The first presented with perimenopausal bleeding and dysmenorrhoea and the symptomswere resolved following the removal of an IUCD. The second presented with postmenopausal bleeding and had a Lippes loop in the uterine cavity.The symptoms resolved after the removal of the device. Source

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