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Chirwa E.C.,University of Bolton | Stephenson R.R.,Technology Consultant | Batzer S.A.,Engineering Institute | Grzebieta R.H.,University of New South Wales
International Journal of Crashworthiness | Year: 2010

A review of most of the existing rollover dynamic devices was conducted in view of assessing their flexibility, reliability, repeatability and crash reconstruction potential. The outcomes indicate the Jordan Rollover System (JRS) to offer the better potential with respect to a repeatable dynamic test procedure in all aspects than the Inverted Drop Test, the Dolly Test Procedure SAE J2114 or FMVSS 208, the Controlled Rollover Impact System, the Corkscrew Rollover System, and above all the newly updated FMVSS 216 Roof Crush Resistance Test. The positive attributes of the JRS are that the device as a research tool is flexible and accurate enough to accommodate most prescribed input conditions; it measures dynamic near and far side impact roof crush loads, not possible with other test devices; it has excellent repeatability en par with the National Highway Traffic Safety Administration and the Insurance Institute for Highway Safety dynamic frontal, side and rear impact tests; it is scientifically acceptable and indeed represents an improvement over other dynamic test devices used by the industry; it provides reliable roof crush and roof crush speed comparisons between vehicles; and it measures cumulative roof crush data believed by many experts in rollover to be a function of head-neck system injury severity. In addition, the JRS is a self-contained device that occupies a small footprint to perform controlled tests within industry-accepted laboratory crash test tolerances at a far more reasonable cost than other test devices. It is the best available dynamic test device in terms of assessing the interaction between roof deformation, occupant kinematics and restraint systems. Original equipment manufacturers and associated researchers can use the device to supplement the new FMVSS 216 in this regard. This is particularly so considering that the next phase of the FMVSS 216 is the development of a dynamic procedure. Moreover, the device can be readily used to star rate rollover crashworthiness of vehicles. © 2010 Taylor & Francis.

Thorbole C.K.,Thorbole Simulation Technologies LLC | Renfroe D.A.,Engineering Institute
International Journal of Crashworthiness | Year: 2013

This paper reports on the modelling of an RCF-67 (invented by Robert C. Fisher [RCF]) buckle and will demonstrate the modal analysis of the spring. A computational model of the side-release RCF-67 buckle is developed using the MADYMO code. This accurate model is used to demonstrate the inadequacy of the computational or analytical model to demonstrate unlatching due to a short-duration pulse, unless the modal properties of the spring are considered. This study clearly indicates that the first resonant mode shape at 2000 Hz shall facilitate the unlatching mechanism. The auto spectrum of the input transient excitation with pulse duration less than 1 ms is capable of exciting a broad range of frequency, including 2000 Hz. The operating deflection shape (ODS) is large when the input excitation puts energy near the resonant frequency, and the ODS is dominated by the mode shape at that resonant frequency. The modal analysis provides an insight regarding the design changes, as required, making this buckle inertial unlatching proof. This then will allow the development of a spring that will not allow the buckle to release under short-duration, high-magnitude dynamic loads. © 2013 Taylor & Francis Group, LLC.

News Article | September 1, 2016
Site: www.rdmag.com

Every week, R&D Magazine will feature an R&D 100 Flashback, chosen from our R&D 100 archive of winners. This week's flashback is Los Alamos National Laboratory's SHMTools, which won in 2015. Structural Health Monitoring (SHM) is quickly becoming an essential tool for improving the safety—and efficient maintenance—of critical structures, such as aircraft, pipelines, bridges, buildings, power plants and wind turbines. Los Alamos National Laboratory engineers have developed SHMTools, a software suite that serves as a modular framework to quickly develop, modify and evaluate custom-designed analysis processes for SHM applications. A: SHMTools provides more than 100 advanced algorithms that can be assembled and evaluated for custom-designed Structural Health Monitoring (SHM) damage-detection processes. It is a virtual toolbox that can be used to detect damage in various types of structures, from aircraft and buildings to bridges and mechanical infrastructure. Using SHMTools, it is possible to detect damage in such structures without removing them from service to correct problems before they become hazardous. Q: What made your winning product better than what already existed? A: SHMTools, including its standardized datasets and examples, is publicly available as open-source for use and expansion by both SHM researchers and practitioners. Thus, the software serves as both a prominent educational tool in the SHM community and a powerful development tool for researchers and industry professionals. The drag-and-drop analysis interface included with the software enables users to quickly prototype and evaluate damage-detection processes. Q: How important was your winning technology to its end application? A: With SHMTools, it is now easy for the SHM community to develop, test, and implement new, improved algorithms designed for specific SHM applications. The ever-increasing volume of SHM algorithms will translate into safer aircraft, infrastructure, and mechanical systems, all of which are critical in humanity’s day-to-day lives. With over 1000 downloads from industry and research institutions around the world, we believe SHMTools has had a measurable impact on the SHM community. Q: Have you changed your winning product since you won the R&D 100 Award? A: Los Alamos National Laboratory continues to support the SHMTools platform to ensure a positive experience for our users. The modular software design and standardized data structures allow users to develop and extend SHMTools with new algorithms to suit their needs. Q: What value did winning an R&D 100 Award provide to you and your organization? A: Recognition of the SHMTools project with an R&D 100 award validated the efforts of the development team and boosted the visibility of the project. This award reaffirms the position of Los Alamos National Laboratory’s Engineering Institute as a leader in the area of Structural Health Monitoring.

Kim S.M.,Engineering Institute | Woo J.S.,Seoul St. Marys Hospital | Jeong C.H.,Seoul St. Marys Hospital | Ryu C.H.,Engineering Institute | And 2 more authors.
Stem Cells Translational Medicine | Year: 2014

Because the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively kills tumor cells, it is one of the most promising candidates for cancer treatment. TRAIL-secreting human mesenchymal stem cells (MSC-TRAIL) provide targeted and prolonged delivery of TRAIL in glioma therapy. However, acquired resistance to TRAIL of glioma cells is a major problem to be overcome.Weshowed a potential therapy that used MSC-TRAIL combined with the chemotherapeutic agent temozolomide (TMZ). The antitumor effects of the combination with MSC-TRAIL andTMZonhumanglioma cells were determined by using an in vitro coculture system and an in vivo experimental xenografted mouse model. Intracellular signaling events that are responsible for the TMZ-mediated sensitization to TRAIL-induced apoptosis were also evaluated. Treatment of either TRAIL-sensitive or -resistant human glioma cells with TMZ and MSC-TRAIL resulted in a significant enhancement of apoptosis compared with the administration of each agent alone. We demonstrated that TMZ effectively increased the sensitivity to TRAIL-induced apoptosis via extracellular signal-regulated kinase-mediated upregulation of the death receptor 5 and downregulation of antiapoptotic proteins, such as X-linked inhibitor of apoptosis protein and cellular FLICE-inhibitory protein. Subsequently, this combined treatment resulted in a substantial increase in caspase activation. Furthermore, in vivo survival experiments and bioluminescence imaging analyses showed that treatment using MSC-TRAIL combined with TMZ had greater therapeutic efficacy than did single-agent treatments. These results suggest that the combination of clinically relevant TMZ and MSC-TRAIL is a potential therapeutic strategy for improving the treatment ofmalignant gliomas. © AlphaMed Press.

Anton S.R.,Los Alamos National Laboratory | Anton S.R.,Engineering Institute | Erturk A.,Georgia Institute of Technology | Inman D.J.,University of Michigan
Journal of Aircraft | Year: 2012

This paper presents the investigation of a multifunctional energy harvesting and energy-storage wing spar for unmanned aerial vehicles. Multifunctional material systems combine several functionalities into a single device in order to increase performance while limiting mass and volume. Multifunctional energy harvesting can be used to provide power to remote low-power sensors on unmanned aerial vehicles, where the added weight or volume of conventional harvesting designs can hinder flight performance. In this paper, a prototype self-charging wing spar containing embedded piezoelectric and battery elements is modeled, fabricated, and tested to evaluate its energy harvesting and storage performance. A coupled electromechanical model based on the assumed modes method is developed to predict the vibration response and voltage response of a cantilevered wing spar excited under harmonic base excitation. Experiments are performed on a representative self-charging wing spar, and the results are used to verify the electromechanical model. The power-generation performance of the self-charging wing spar is investigated in detail for harmonic excitation in clamped-free boundary conditions. Experiments are also conducted to demonstrate the ability of the wing spar to simultaneously harvest and store electrical energy in a multifunctional manner. It is shown that, for an input base acceleration level of ± 0:25 g at 28.4Hz at the base of the structure, 1.5mW of regulated dc power is delivered from the piezoelectric layers to the thin-film battery, resulting in a stored capacity of 0.362 mAh in 1 h. Copyright © 2011 by Luis Delgado.

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