Justice Basheer Ahmed Sayeed College for Women

Chennai, India

Justice Basheer Ahmed Sayeed College for Women

Chennai, India
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Gladies Kezia J.,Madras Christian College | Mubeen Sultana D.,Justice Basheer Ahmed Sayeed College for Women | Dawood N.,Justice Basheer Ahmed Sayeed College for Women | Sharief D.,The New College | Joyce Priyakumari C.,Madras Christian College
International Journal of Pharmaceutical Sciences Review and Research | Year: 2014

In the present study, Methyl parathion an organophosphate compound has been induced to the rats to study the activity of acetylcholinesterase on different regions of the brain for acute effects and then an antidote Centella asiatica was given to the rats which were induced with methylparathion.

Punitha S.C.,Justice Basheer Ahmed Sayeed College for Women | Punitha S.C.,Bharathiar University | Rajasekaran M.,SASTRA University
Bangladesh Journal of Pharmacology | Year: 2016

The present study examined the cardioprotective role of methanol extract of the edible mushroom Volvariella volvacea against oxidative stress in hyperglycemic rats. Rats divided into 6 groups were administered with nicotinamide and streptozotocin intraperitoneally, except Group I (control). Group II served as diabetic control. Group III was given glibenclamide. Two groups (IV and V) of rats received (200 and 400 mg/kg) mushroom extracts orally for 30 days and Group VI received vitamin E (40 mg/kg). After the treatment period, lipid peroxides, carbonyl end products, advanced glycation end products, reduced glutathione, glutathione peroxidase, glutathione-S transferase, catalase, superoxide dismutase and non-enzymatic anti-oxidants (vitamin C and E) were assessed in the heart tissues of experimental animals. Glycosylated hemoglobin was estimated in blood. Electrocardiography recordings of the treated groups were also done. The results showed that mushroom extract treatment reduced the lipid peroxides, advanced glycation end products and protein carbonyls significantly and reversed the altered anti-oxidant enzymes, and the vitamins. © 2016, Bangladesh Pharmacological Society. All rights reserved.

Veerabadran U.,Quaid E Milleth Government Arts College for Women | Venkatraman A.,Justice Basheer Ahmed Sayeed College for Women | Souprayane A.,University of Madras | Narayanasamy M.,University of Madras | And 5 more authors.
Asian Pacific Journal of Tropical Disease | Year: 2013

Objective: To investigate the antioxidant and antiproliferative potential of Leonotis nepetifolia (L. nepetifolia) leaves. Methods: The leaves of L. nepetifolia were subjected to extraction using three different solvents and the antioxidant potential of those extracts were tested by using various in vitro assays. Further, the best screened extract was analyzed for its phytochemical profile by both qualitative and quantitative assays. In order to determine its anti-proliferative activity, the best screened extract was treated with breast and laryngeal cancer cell lines such as MCF-7 cells and Hep2 cells, respectively. The cytotoxicity of the extract was also studied using MTT assay. The inhibitory effect of the extract of leaves of L. nepetifolia on the selected cell-line DNA was determined by DNA fragmentation assay. Also, the extract was subjected to TLC and bioautography analysis. Results: The DPPH assay showed methanol extract of L. nepetifolia leaves to be more significant in scavenging free radicals with inhibition percentage of 60.57. %. From the data obtained, the methanol extract proved to be significant in all anti-oxidant assays and this effect was well comparable with the standard used in the study. The predominant phytochemicals such as phenols and flavonoids were further quantified as 0.107. % and 0.089. %. The cytotoxicity assay showed that the cell viability increased with increasing concentration of methanol extract. In addition, the extract caused dose dependent damage to the cancer cell lines MCF-7 and Hep2. Conclusions: Our study suggests that the leaves of L. nepetifolia were significant in scavenging free radicals and causing damage to proliferative cells. Further mechanistic studies would help in proving the efficiency of the selected plant under in vivo conditions. © 2013 Asian Pacific Tropical Medicine Press.

Sadhiya Banu I.,University of Madras | Sadhiya Banu I.,Justice Basheer Ahmed Sayeed College for Women | Prakash H.,University of Madras | Natarajan P.,University of Madras
Inorganica Chimica Acta | Year: 2011

The photoreactions of tris(2,2′-bipyridine)nickel(II) complex, Ni(II)(bpy3)2+ were studied and compared with that of the photoreactions of 2,2′-bipyridine ligand. Continuous photolysis of the complex shows that the photodecomposition corresponds to the absorption of light by the complex in the ligand centered excited state. Flash photolysis of the complex using a 248 nm excimer laser yields bipyridine cation radical and solvated electron as transients. Absorption spectra of the transient observed for the complex is found to be similar to that observed for the ligand on flash excitation using a 248 nm laser suggesting that the transients observed in the case of complex is due to the coordinated bipyridine in the complex. The formation of solvated electron is observed to be monophotonic and that of the bipyridine cation radical is found to be a biphotonic process. Significant change in Ni-N bond distance upon oxidation of Ni(bpy3)2+ ion when compared to that observed in nickel(II)tetraazamacrocyclic complexes suggests that the formation of the trivalent complex by photolysis is not favored for the Ni(bpy3)2+ ion and CTTS excited state in the complex is not observed in the present system. © 2011 Elsevier B.V. All rights reserved.

Azeezaa V.,Sathyabama University | Azeezaa V.,SRR Engineering College | Arul Pragasam A.J.,Sathyabama University | Sunitha T.G.,Pachaiyappas College | And 2 more authors.
Acta Physica Polonica A | Year: 2015

Nonlinear optical single crystals of L-cysteine hydrochloride monohydrate (LCB) were grown by slow evap-oration technique. Single crystal X-ray diffraction analysis revealed the crystal system and helped to determine lattice parameter values. Powder X-ray diffraction analyses were carried out and the diffraction patterns were indexed. The optical properties of the crystals were determined using UV-visible spectroscopy. Optical con-stants such as refractive index, extinction coeffcient and electric susceptibility were determined from UV-visible spectroscopy. The Fourier transform infrared studies confirmed the various functional groups present in the grown crystal. The mechanical behaviour of the grown crystals was studied using Vicker's microhardness tester. The ther-mal analysis confirmed that the crystal was stable up to 108.7°C. The dielectric constant and the dielectric loss measurements were carried out for different temperatures and frequencies. Second harmonic generation of LCB crystal was investigated by the Kurtz powder technique.

Ponmani K.,Presidency College at Chennai | Nayeemunisa S.M.,Presidency College at Chennai | Nayeemunisa S.M.,Justice Basheer Ahmed Sayeed College for Women | Kiruthika S.,SRM University | Muthukumaran B.,Presidency College at Chennai
Ionics | Year: 2015

In the present work, carbon-supported Pt–Sn, Pt–Ru, and Pt–Sn–Ru electrocatalysts with different atomic ratios were prepared by alcohol-reduction method to study the electro-oxidation of ethanol in membraneless fuel cells. The synthesized electrocatalysts were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDX), and X-ray diffraction (XRD) analyses. The prepared catalysts had similar particle morphology, and their particle sizes were 2–5 nm. The electrocatalytic activities were characterized by cyclic voltammetry (CV) and chronoamperometry (CA). The electrochemical results obtained at room temperature showed that the addition of Sn and Ru to the pure Pt electrocatalyst significantly improved its performance in ethanol electro-oxidation. The onset potential for ethanol electro-oxidation was 0.2 V vs. Ag/AgCl, in the case of the ternary Pt–Sn–Ru/C catalysts, which was lower than that obtained for the pure Pt catalyst (0.4 V vs. Ag/AgCl). During the experiments performed on single membraneless fuel cells, Pt − Sn − Ru/C (70:10:20) performed better among all the catalysts prepared with power density of 36 mW/cm2. The better performance of ternary Pt–Sn–Ru/C catalysts may be due to the formation of a ternary alloy and the smaller particle size. © 2015 Springer-Verlag Berlin Heidelberg

Anuswedha A.,Justice Basheer Ahmed Sayeed College for Women | Rao U.A.,Ragas Dental College and Hospital
International Journal of Pharma and Bio Sciences | Year: 2015

Garlic (Allium sativum L.) and ginger (Zingiber officinale R.) has been used for thousands of years for medicinal purposes. Historically, garlic has been used worldwide to fight bacterial infections. Multi-drug resistant bacteria and their incidence has risen dramatically in recent years. Allium vegetables, particularly garlic (Allium sativum L.) exhibit a broad antibiotic spectrum against both grampositive and gram-negative bacteria. Methicillin Resistant Staphylococcus aureus (MRSA) are the major cause of nosocomial infections including pneumonia, postoperative wound infection, bacteremia and other infections worldwide. The in vitro antibacterial activity of crude extracts and fresh juice of Allium sativum L. (garlic), Allium ampeloprasum L.(elephant garlic) and Zingiber officinale R.(ginger) was determined and compared against clinical strains of methicillin resistant Staphylococcus aureus. Allium ampeloprasum fresh juice showed maximum inhibition against all the MRSA strains at a concentration of 100μl/ml followed by the fresh juice of Allium sativum. The crude extracts and fresh juice of Zingiber officinale showed no activity at the concentration tested. This study confirms the higher therapeutic potential of Allium ampeloprasum and Allium sativum against MRSA.

Nayeemunisa S.M.,Presidency College at Chennai | Nayeemunisa S.M.,Justice Basheer Ahmed Sayeed College for Women | Kiruthika S.,SRM University | Muthukumaran B.,Presidency College at Chennai
International Journal of ChemTech Research | Year: 2015

This paper presents the development of membraneless sodium perborate fuel cell. Investigation of the cell operation is conducted by using isopropanol as a fuel and sodium perborate as an oxidant. The cell converts the energy released by H2O2decomposition with H+and OH− ions into electricity and produces water and oxygen. Such a novel design eliminates the need of a membrane, in which acid and alkaline electrolytes contact with each other. The effects of flow rates and the concentrations of various species at both the anode and cathode on the cell performance are also investigated. At room temperature, the laminar flow-based microfluidic membraneless fuel cell can reach a maximum power density of 23.8 mW/cm2. The developed fuel cell emits no CO2, features no proton exchange membrane, inexpensive catalysts, and simple planar structure, which enables high design flexibility and easy integration of the microscale fuel cell into actual microfluidic systems and portable power applications. © 2015 Sphinx Knowledge House. All Rights Reserved.

Siva Sankar R.,Pondicherry University | Sumitha J.,Justice Basheer Ahmed Sayeed College for Women | Kaviarasan T.,Pondicherry University | Yogamoorthi A.,Pondicherry University
Indian Journal of Marine Sciences | Year: 2013

Bacteria associated with hemolymph, gut and muscle of Ocypode platytarsis were investigated using three different agar media such as seawater yeast extract peptone agar, zobell marine agar and nutrient agar. Among them, sea water yeast extract peptone agar provided an excellent growth opportunity to the bacteria and showed higher counts. A total 117 bacterial isolates were obtained from 40 ghost crabs representing totally 9 bacterial species, comprising of the Gram-positive coccus, Gram-negative bacilli, Gram-positive rod and Gram-negative rod. Micrococcus was the dominant genus found in all parts of ghost crab, O. platytarsis. Further, the antibiotics such as chloramphenicol, ciprofloxacin and gentamycin showed excellent susceptibility against all the bacterial species, whereas the bacterial strain isolated from the crab are resistant to amoxicillin, nalidixic acid and oxacillin. Results indicate that the bacteria associated with O. platytarsis are considered as potential human pathogens and some of the isolates were resistant to antibiotics.

Noorjahan C.N.,Justice Basheer Ahmed Sayeed College for Women
Pollution Research | Year: 2010

The physico chemical parameters (pH, EC, BOD, COD, TD8, T88, Chromium, Copper and Zinc) of 100% treated textile effluent and its effects on the biochemical constituents present in the gills, liver and muscle of Ttlapia mossambica were studied. The results of analysis of physico chemical parameters of 100% treated textile effluent revealed that the parameters such as pH, EC, BOD, COD, TD8, TSS were found to be higher than the permissible limits of CPCB (1995) thereby indicating the high pollutional potential of the effluent. The biochemical estimation revealed that lipid depletion was followed by carbohydrate and protein in all the three organs, i.e., gills and muscle in the decreasing trend exposed to treated textile effluent and gills were most affected compared to liver and muscle. Copyright © EM International.

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