Saitama, Japan
Saitama, Japan

Jumonji University is a private women's college in Niiza, Saitama, Japan, established in 1996. The predecessor of the school was founded in 1922. Wikipedia.

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Iwanuma S.,Waseda University | Iwanuma S.,Japan Society for the Promotion of Science | Akagi R.,Japan Institute of Sports science | Kurihara T.,Ritsumeikan University | And 4 more authors.
Journal of Applied Physiology | Year: 2011

The present study determined in vivo deformation of the entire Achilles tendon in the longitudinal and transverse directions during isometric plantar flexions. Twelve young women and men performed isometric plantar flexions at 0% (rest), 30%, and 60% of the maximal voluntary contraction (MVC) while a series of oblique longitudinal and cross-sectional magnetic resonance (MR) images of the Achilles tendon were taken. At the distal end of the soleus muscle belly, the Achilles tendon was divided into the aponeurotic (ATapo) and the tendinous (ATten) components. The length of each component was measured in the MR images. The widths of the Achilles tendon were determined at 10 regions along ATapo and at four regions along ATten. Longitudinal and transverse strains were calculated as changes in relative length and width compared with those at rest. The ATapo deformed in both longitudinal and transverse directions at 30%MVC and 60%MVC. There was no difference between the strains of the ATapo at 30%MVC and 60%MVC either in the longitudinal (1.1 and 1.6%) or transverse (5.0∼11.4 and 5.0∼13.9%) direction. The ATten was elongated longitudinally β.3%) to a greater amount than ATapo, while narrowing transversely in the most distal region (-4.6%). The current results show that the magnitude and the direction of contraction-induced deformation of Achilles tendon are different for the proximal and distal components. This may be related to the different functions of Achilles tendon, i.e., force transmission or elastic energy storage during muscle contractions. Copyright © 2011 the American Physiological Society.


Sumi K.,Future University Hakodate | Nagata M.,Jumonji University
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2013

This paper describes an experiment on conveying the messages of stories to users. We investigated what kind of story and what kind of character, in terms of the level of abstraction, should be applied to convey a story's message. The animated stories used in the experiment were created using WordsAnime, a software tool for creating animation content easily from an input scenario. The experiment was then conducted by showing subjects animated stories with varying levels of abstraction for the story and the central character. © 2013 Springer-Verlag Berlin Heidelberg.


Sumi K.,Future University Hakodate | Nagata M.,Jumonji University
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2013

Considering the spread of computers and the technological advances of recent years, research on persuasive intelligent user interfaces with a fifty-fifty relationship for communicating with humans is necessary. Recently, anthropomorphic user interfaces have been developed, such as virtual agents and robots. In this paper, we introduce an experiment on the effect on a human of persuasive interaction with a virtual agent which is capable of facial and verbal expression. Then, considering the results, we discuss an experiment on persuasion to maintain motivation, comparing human agent interaction and human robot interaction. © 2013 Springer-Verlag Berlin Heidelberg.


Hashimoto T.,Nippon Shinyaku Co. | Ide T.,Jumonji University
Journal of Agricultural and Food Chemistry | Year: 2015

We investigated the physiological activity of naringenin in affecting hepatic lipogenesis and serum and liver lipid levels in rats. Rats were fed diets containing 0, 1, or 2.5 g/kg naringenin for 15 d. Naringenin at a dietary level of 2.5 g/kg significantly decreased the activities and the mRNA levels of various lipogenic enzymes and sterol regulatory element binding protein-1c (SREBP-1c) mRNA level. The activities and the mRNA levels were also 9-22% and 12-38% lower, respectively, in rats fed a 1 g/kg naringenin diet than in the animals fed a naringenin-free diet, although the differences were not significant in many cases. Naringenin at 2.5 g/kg significantly lowered serum triacylglycerol, cholesterol, and phospholipid and hepatic triacylglycerol and cholesterol. This flavonoid at 1.0 g/kg also significantly lowered these parameters except for serum triacylglycerol. Naringenin levels in serum and liver dose-dependently increased, and hepatic concentrations reached levels that can affect various signaling pathways. © 2015 American Chemical Society.


Ide T.,Japan National Food Research Institute | Ide T.,Jumonji University
British Journal of Nutrition | Year: 2014

In the present study, the mRNA levels of hepatic proteins involved in the drug metabolism of rats fed α-lipoic acid were evaluated by DNA microarray and real-time PCR analyses. Experimental diets containing 0, 0·1, 0·25 and 0·5 % (w/w) α-lipoic acid were fed to four groups of rats consisting of seven animals each for 21 d. DNA microarray analysis revealed that the diet containing 0·5 % α-lipoic acid significantly (P< 0·05) increased the mRNA levels of various phase I drug-metabolising enzymes up to 15-fold and phase II enzymes up to 52-fold in an isoenzyme-specific manner. α-Lipoic acid also up-regulated the mRNA levels of some members of the ATP-binding cassette transporter superfamily, presumed to be involved in the exportation of xenobiotics, up to 6·6-fold. In addition, we observed that α-lipoic acid increased the mRNA levels of many proteins involved in antioxidation, such as members of the thiol redox system (up to 5·5-fold), metallothioneins (up to 12-fold) and haeme oxygenase 1 (1·5-fold). These results were confirmed using real-time PCR analysis, and α-lipoic acid dose dependently increased the mRNA levels of various proteins involved in drug metabolism and antioxidation. Consistent with these observations, α-lipoic acid dose dependently increased the hepatic concentration of glutathione and the activities of glutathione reductase and glutathione transferase measured using 1-chloro-2,4-dinitrobenzene and 1,2-dichloro-4-nitrobenzene as substrates, but decreased the hepatic and serum concentrations of malondialdehyde. In conclusion, the present study unequivocally demonstrated that α-lipoic acid increases the mRNA expression of proteins involved in drug metabolism and antioxidation in the liver. Copyright © The Author 2014.


Ide T.,Jumonji University
Journal of Clinical Biochemistry and Nutrition | Year: 2012

We previously demonstrated that a diet containing fish oil at a level of 80 g/kg strongly stimulated the physiological activity of a sesame sesamin preparation containing sesamin and episesamin at equal amounts to increase hepatic fatty acid oxidation. This study was conducted to clarify whether fish oil at lower dietary levels enhances the physiological activity of sesamin to increase hepatic fatty acid oxidation. Rats were fed experimental diets supplemented with 0 or 2 g sesamin/kg, and containing 0, 15 or 30 g fish oil/kg for 15 days. Among rats fed sesamin-free diets, diets containing 15 and 30 g fish oil/kg slightly increased the activity of enzymes involved in hepatic fatty acid oxidation. Sesamin increased these values irrespective of the presence or absence of fish oil in diets; however, the extent of the increase of many parameters was much greater in rats given fish oil-containing diets than in those fed a fish oil-free diet. Diets simultaneously containing sesamin and fish oil increased the gene expression of various peroxisomal fatty acid oxidation enzymes in a synergistic manner; but they were ineffective in causing a synergistic increase in mRNA levels of mitochondrial fatty acid oxidation enzymes. The extent of the synergistic increase in the activity of hepatic fatty acid oxidation enzymes and mRNA levels of the peroxisomal enzymes was indistinguishable between diets containing 15 and 30 g fish oil/kg and appeared comparable to that observed previously with a diet containing 80 g fish oil/kg. ©2012 JCBN.


Yasuda T.,Jumonji University | Kobayashi H.,Tokyo Denki University
Proceedings - IEEE International Workshop on Robot and Human Interactive Communication | Year: 2015

To construct mind-reading robots, it is important to correctly identify the communicative intention of humans. In human environments, there are usually an enormous number of objects, and each object has many different parts. Therefore, referring to an object or an object part in current communication is not an easy task. We use both linguistic and nonlinguistic information to specify such referential intentions, but exactly how nonlinguistic information is used has not been examined in detail. In this study, video data from eight pairs of adult addressers and addressees who communicated about whole-object or object-part labels were analyzed. The addressers' utterances were transcribed, and nouns and demonstrative words were extracted. Hand motions were divided into five categories: showing, pointing, stroking, functional action, and other. Gaze data obtained using eye movement recordings were also coded using the following categories: gaze on object, face, or body of the experimenter and other. Gaze on object was further divided into two categories; critical and noncritical object parts. The results showed that participants used different patterns of hand motions and gaze to refer to whole-object and object-part labels. When they taught whole-object labels, they showed the object and looked at the addressee's face. When they taught object-part labels, they pointed at, stroked, and looked at the object part. Based on the results, we propose the concept of action contrast in human communication of referential intention. We propose that the need for specification and the use of actions in a contrasting manner are related. Nonlinguistic cues, such as pointing and showing, and timing of utterances are important sources of information that specify human referential intentions in the environment. Action contrast is an important source of information specifying addressers' referential intentions, which can be utilized to construct mind-reading robots. © 2014 IEEE.


Ito S.,Tokyo Institute of Technology | Izumi N.,Jumonji University | Hagihara S.,Tokyo Institute of Technology | Yonezaki N.,Tokyo Institute of Technology
10th IEEE International Conference on Bioinformatics and Bioengineering 2010, BIBE 2010 | Year: 2010

We developed a method for analyzing the dynamics of gene regulatory networks in purely qualitative fashion. In our method, constraints for possible behaviors of a network and a biological property of interest are described as Linear Temporal Logic formulas, being automatically analyzed by satisfiability checking. In this way, we can investigate whether there exists some behavior which satisfies a specified property or whether all the behaviors satisfy a specified property, which are difficult in quantitative analysis. © 2010 IEEE.


Shinoda S.,Tokyo Metroplitan University | Yoshizawa S.,Tokyo Metroplitan University | Nozaki E.,Tokyo Metroplitan University | Tadai K.,Tokyo Metroplitan University | Arita A.,Jumonji University
American Journal of Physiology - Gastrointestinal and Liver Physiology | Year: 2014

Regular "mucosal block" is characterized by decreased uptake of a normal iron load 3-72 h after the administration of excess iron (generally 10 mg) to iron-deficient animals. We found that shortacting mucosal block could be induced by much lower iron concentration and much shorter induction time than previously reported, without affecting levels of gene expression. A rapid endocytic mechanism was reported to decrease intestinal iron absorption after a high iron load, but the activating iron load and the time to decreased absorption were undetermined. We assessed the effects of 30-2,000 Μg iron load on iron uptake in the duodenal loop of iron-deficient and iron-sufficient rats under anesthesia. One hour later, mucosal cellular iron uptake in iron-deficient rats administered 30 μg iron was 76.1%, decreasing 25% to 50.7% in rats administered 2,000 Μg iron. In contrast, iron uptake by iron-sufficient rats was 63% (range 60.3- 65.5%) regardless of iron load. Duodenal mucosal iron concentration was significantly lower in iron-deficient than in iron-sufficient rats. Iron levels in portal blood were consistently higher in iron-deficient rats regardless of iron load, in contrast to the decreased iron uptake on the luminal side. Iron loading blocked mucosal uptake of marginally excess iron (1,000 μg), with a greater effect at 15 min than at 30 min. The rapid induction of short-acting mucosal block only in irondeficient rats suggests DMT1 internalization. © 2014 the American Physiological Society.


Ide T.,Jumonji University
Journal of Clinical Biochemistry and Nutrition | Year: 2014

We studied the combined effect of sesamin (1:1 mixture of sesamin and episesamine) and soybean phospholipid on lipid metabolism in rats. Male rats were fed diets supplemented with 0 or 2 g/kg sesamin, and containing 0 or 50 g/kg soybean phospholipid, for 19 days. Sesamin and soybean phospholipid decreased serum triacylglycerol concentrations and the combination of these compounds further decreased the parameter in an additive fashion. Soybean phospholipid but not sesamin reduced the hepatic concentration of triacylglycerol. The combination failed to cause a strong decrease in hepatic triacylglycerol concentration, presum- ably due to the up-regulation of Cd36 by sesamin. Combination of sesamin and soybean phospholipid decreased the activity and mRNA levels of hepatic lipogenic enzymes in an additive fashion. Sesamin strongly increased the parameters of hepatic fatty acid oxidation enzymes. Soybean phospholipid increased hepatic activity of 3-hydroxyacyl-CoA dehydrogenase although it failed to affect the activity of other enzymes involved in fatty acid oxidation. Sesamin strongly increased hepatic concentration of carnitine. Sesamin and soybean phospholipid combination further increased this parameter, accompanying a parallel increase in mRNA expression of carnitine transporter. These changes can account for the strong decrease in serum triacylglycerol in rats fed a diet containing both sesamin and soybean phospholipid. ©2014 JCBN.

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