Karachi, Pakistan
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Objective: Psoriasis is a chronic inflammatory skin disease of unknown origin. Different factors might be influencing its course. The aim of our study was to observe and analyze different clinoepidemiological variables of psoriasis in patients reporting to a tertiary care hospital in Karachi. Study Design: Prospective study Place and Duration of Study: This study was conducted at Jinnah Postgraduate Medical Centre, Karachi, Pakistan from January 2014 to December 2014. Materials and Methods: 200 patients (116 Males and 84 females) ages 18 and above with mild to severe psoriasis were selected and assessed on one occasion which included detailed history and examination. All data was documented on completion of study. Results: A total 200 cases were studied. 90% had chronic plaque psoriasis. There was male preponderance with a male to female ratio of 1.38:1. Mean peak age of onset was 11-20 years of age and was earlier in females than males. More than two-third of patients had onset of psoriasis before or at 40 years of age. Familial occurrence was present in 38% of patients and 35% had first degree relative involvement. Psoriatic arthropathy was present in 35% of patients. 86.36% of the patients with arthropathy had onset of psoriasis before 40 years of age. 21% of patients reported worsening of their psoriasis with sun. 32% of the patients in this study were smokers and most of them were males. Conclusion: The findings of this study done in Karachi, Pakistan correlates with previous hospital-based studies done in different parts of the world.

News Article | November 6, 2016

— New York’s innovative neurosurgeon, Dr. Saeed Bajwa has been chosen to join The Leading Physicians of the World, an organization recognizing doctors of excellence from across each field of medical specialization. Already an esteemed Fellow of the American College of Surgeons, the International College of Surgeons and the American Association of Neurological Surgeons, Dr. Bajwa was recently distinguished for his years of dedication, experience and superior patient care, and for his impressive, pioneering approach to the surgical treatment of the brain and spine. His inclusion in the respected medical group’s annual journal underscores a lifelong commitment to professional development and his insistence on using the most technologically advanced methods available. The Pakistani-born doctor’s well-earned reputation comes not only from an earnest drive to help those suffering from disease and chronic pain, but from his ability to keep his practice at the vanguard of medical progress. This forward-thinking approach can be traced back to 1976, when he received his MD degree at Nishtar Medical College of the University of Punjab in Lahore, Pakistan, where he was a gold medal recipient for First Position in Surgery. After completing his residency in General Surgery and Neurosurgery at the Combined Military Hospital in Lahore, Dr. Bajwa moved to the United States where he completed post-graduate studies in General Surgery at New York’s Mount Sinai Hospital, followed by two years in Philadelphia undertaking Neurosurgical training at the Medical College of Pennsylvania. In the two following years, he attended State University of New York Upstate Medical University in Syracuse, where the SUNY Health Science Center elected him to the national honor medical society, Alpha Omega Alpha, as well as presented him with the Distinguished Teaching Award for his work in education. As a specialist who now joins The Leading Physicians of the World, Dr. Saeed Bajwa’s learning is clearly an ongoing quest. Over the course of his thirty-year career, he has strengthened his extensive knowledge of neurological surgery by consistently training on the latest groundbreaking medical technology in the company of other leading specialists. In 2004, he was involved in the development of an artificial disc for alleviating lower back pain with DePuy Spine, a Johnson & Johnson company. He later became an early adopter of applications like the CyberKnife Robotic Radiosurgery System, a tool that emits focused doses of high radiation to inoperable tumors anywhere on the body. His patient-centered philosophy led him to American Spine in Maryland, where in August of 2015, he completed a certification program in Endoscopic and Minimally Invasive Operations of the Lumbar and Thoracic Spine. Last year he also acquired MAZOR robotics for his practice at Southern New York NeuroSurgical Group, P.C. in Binghamton, NY; Dr. Bajwa is one of very few surgeons certified to use MAZOR, the minimally invasive procedural instrument that allows for precise treatment of scoliosis, vertebral compression fractures and spinal deformities. His many accomplishments place him at the forefront of neurosurgery. Dr. Saeed Bajwa has delivered more than 100 speeches to community-based physicians on the topics of Neurology and Neurosurgery. He is affiliated with Wilson Regional Medical Center (Johnson City, NY), Binghamton General Hospital (Binghamton, NY), Lourdes Hospital (Binghamton, NY) and SUNY Upstate Medical University Hospital (Syracuse, NY) and serves on the boards of many community services dedicated to serving people with neural and spinal injuries. Additionally, Dr. Bajwa has generously donated to the Tameer-e-Nau Trust, which provides education and medical assistance for underprivileged communities of Pakistan. In 2012, he helped develop the first CyberKnife Radiosurgery Center for Pakistan at the Jinnah Postgraduate Medical Center (JPMC) in Karachi, and founded two premier institutions: Shifa International Hospital in Islamabad and Doctors Hospital and Medical Center in Lahore, Pakistan. Dr. Saeed Bajwa Proud Recepient of The ICNA Relief USA Award of Appreciation: Spine surgeon leader to know: Dr. Saeed Bajwa of Southern New York Neurosurgical Group: For more information, please visit

Dixit S.,Deloitte | Singh M.K.,JPMC
International Conference and Workshop on Emerging Trends in Technology 2011, ICWET 2011 - Conference Proceedings | Year: 2011

Databases and other related concepts are some of the key technologies that power the present IT scenario. Their effect can be felt in all the industries and thus database designing forms a key part in development of any system. In such a scenario coupled with the demanding environment it is imperative that the design is flawless and all the related aspects are well thought of. Such high quality and zero tolerance work require individuals who are highly trained and have complete visibility. Through this paper we present the alternate ways of viewing and visualizing a database in its entirety making use of the thickness of the screen as an additional dimension. One of our prime motives is also to inculcate an additional methodology for imbibing database knowledge among beginners. The alternate view of the conceptual model described in this paper can also be used to find relationships, distinguishing features and other points of interest among database tables, views, warehouses, schemas and transformations. Copyright © 2011 ACM.

Saleem Q.A.,JPMC | Cheema A.M.,JPMC | Tahir M.A.,JPMC | Dahri A.R.,JPMC | And 2 more authors.
BMC Research Notes | Year: 2013

Background: The purpose of this study was to measure the success rate of unilateral lateral rectus recession and medial rectus resection in primary exotropia. Methods. This is an interventional case series of 55 patients with primary exotropia (degree of deviation 15-85 PD), above the age of 5 years. Patients were treated in the Department of Ophthalmology, Jinnah Postgraduate Medical Center, Karachi, Pakistan, during the period of July 2009 to March 2010. All the patients underwent surgical procedure i.e., lateral rectus muscle recession (maximum up to 10 mm) and medial rectus muscle resection (up to 6 mm) of one eye, according to the Park's method. Surgery was done based on prism cover test measurements obtained at 6 m with appropriate optical correction in place. Patients were re evaluated at one day, one month, two months and six months post operatively. Final outcome was considered at the end of six months at which achievement of ≤10 PD of exotropia was the success. Data was analyzed on SPSS version 17.0. Results: We obtained success (≤10 PD) in 42 out of 55 patients (76.4%) and 13 out of 55 patients (23.6%) did not meet our criteria for surgical success (>10 PD). Analysis of success with the type of primary exotropia showed that success was achieved in 22 out of 24 cases of intermittent type (91.6%) and 20 out of 31 cases of constant type (64.5%)(P Value 0.019). The highest percentage of success was achieved in patients with the pre-operative deviation of ≤70 PD i.e., 93.3% (42 out of 45 cases), while none of the patients with the pre-operative deviation of >70 PD (10 out of 10 cases) achieved the criteria for success. Conclusion: We conclude that pre-operative deviation is one of the strongest predictor for favorable surgical outcome. Therefore, eliminating the factors causing error in the correct determination of pre-operative deviation should improve the success and predictability of the surgical outcome. Despite the obstacles in the surgical management of strabismus, our results are encouraging. © 2013 Saleem et al.; licensee BioMed Central Ltd.

Shaikh I.,SMBBMU | Rai P.,SMBBMU | Khoso B.K.,JPMC
Medical Forum Monthly | Year: 2015

Objective: To assess the various ocular manifestations in xeroderma pigmentosum seen at Eye and Dermatology Department of Chandka Medical College Hospital Larkana. Study Design: Prospective study Place and Duration of Study: This study was carried out at two Departments, i.e. at Departments of Dermatology and Ophthalmology of Chandka Medical College larkana from January 2013 to December 2014. Material and methods: Twenty cases were enrolled from outpatient of Eye and Skin Department, Chandka Medical College Hospital Larkana. Patients were subjected to detail history, complete eye and skin examination and relevant investigations. Results: 20 patients, 12(60%) males and 8 (40%) females with xeroderma pigmentosum in a gender ratio of 1.5 : 1 were recruited. All patients had skin freckles and increased sensitivity to sun light. Photophobia and conjunctivitis was seen in 18(90%) cases, keratitis and dry eyes was seen in 12 (60%) cases and 4 (20%) cases had malignancies of lids and conjunctiva proved on biopsy. Our cases belongs to larkana and sukkur division. Conclusion: The present study highlights the eye involvement in xeroderma pigmentosum and thereby early detection of eye disease prevent the malignancies and blindness.

Zain S.,Saleem Center North Karachi | Khan M.,BMSI | Alam R.,University of Karachi | Zafar I.,Hamdard University | Ahmed S.,JPMC
Journal of the Pakistan Medical Association | Year: 2013

Objective: To compare the efficacy and safety of topiramate with gabapentin in the prophylaxis of migraine patients. Methods: A 12-week randomised open label control trial was conducted at the Department of Pharmacology and Therapeutics, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre (JPMC), Karachi from January to March 2011 involving 80 outpatients who had a history of migraine. The sample was divided into two equal groups. Primary efficacy measure was changed into mean monthly migraine frequency. Secondary efficacy measure included reduction in severity and average duration of an attack. Chi square test and paired t-test were used to analyse the data through SPSS 15. Result: Reduction in mean monthly migraine frequency (10.67±4.25 to 1.82±2.02) in the topiramate group was significantly greater compared with (11.97±4.452 to 2.73±2.59) that in the gabapentin group (p<0.001). Reduction in severity from 6.60±2.122 to 1.03±0.92 in the topiramate group was also significantly greater compared with 6.93±1.90 to 1.18±1.01 in the gabapentin group (p<0.001). Reduction in the average duration of attacks from 25.77±22.32 hours to 1.05±1.06 hours in the topiramate group was significantly greater compared with 22.20±20.72 to 1.08±1.40 hours in the gabapentin group (p<0.001). Weight loss and numbness were common adverse effects in the topiramate group. Dizziness, weight gain and somnolence were reported in the gabapentin group. Conclusion: Gabapentin appeared well tolerated in 30(75%) patients compared to topiramate in 23(57.5%) patients. Both drugs were equally effective in migraine prophylaxis.

Objective: To compare the quality of life by using two therapeutic approaches (10% sulphur ointment and 5% permethrin cream) in patients with scabies. Study Design: Retrospective/comparative study. Place and Duration of Study: This study was conducted in Basic Medical Science Institute and Dermatology Department of Jinnah Postgraduate Medical Centre in Karachi from 1st Dec 2010 to 30th May 2011. Materials and Methods: This study sample consisted of 130 (4 dropped out) clinically diagnosed cases of scabies divided into two groups; A and B. Each group was further subdivided into three age groups. Group A was asked to apply 5% permethrin cream on day 0 and to be repeated after 15 days and Group B treated with 10% sulphur ointment for three consecutive nights and repeated on day 15. Data was gathered by a questionnaire. Patients follow up was done on days 3, 15 and 30 and quality of life was determined on day 0 and 30 by using Dermatological Life Quality Index. Results: Quality of life was found to be low in scabies patients and treatment with 10% sulphur ointment and 5% permethrin not only improved clinical symptoms but also their quality of life significantly. Conclusion: Scabies affects quality of life because of severe itching and lack of sleep and proper topical therapy significantly improves clinical symptoms and quality of life.

Dixit S.,Deloitte | Singh M.K.,JPMC
Proceedings - PACCS 2011: 2011 3rd Pacific-Asia Conference on Circuits, Communications and System | Year: 2011

currently there exists no single model to represent a database and it ancillary systems. One has to resort to a number of conceptual models to depict the system based on requirements. Through this paper we present the alternate ways of viewing and visualizing a database in its entirety making use of the thickness of the screen as an additional dimension. One of our prime motives is also to inculcate an additional methodology for imbibing database knowledge among beginners. The alternate view of the conceptual model described in this paper can also be used to find relationships distinguishing features and other points of interest among database tables views warehouses schema and transformations. © 2011 IEEE.

PubMed | University of Karachi, Liaquat National Hospital and JPMC
Type: Journal Article | Journal: JPMA. The Journal of the Pakistan Medical Association | Year: 2016

To analyse the frequency of different types of amblyopia and its association with gender.The cross-sectional study was conducted from March 2014 to October 2014 at the Department of Ophthalmology of a tertiary care hospital inKarachi. The patients were classified into different types of amblyopia like anisometropic, strabismic, sensory deprivation and meridional amblyopia. Stratification was done according to age, gender and type of amblyopia by using SPSS version 21.Out of 130 patients, 71 were male and 59 were female. The amblyopia rate determined was anisometropic 69.23%, strabismic amblyopia 21.51% and others 9.23%. The mean age of subjects was 18.029 years. Type of amblyopia was independent of gender, and anisometropic amblyopia was the most common type of amblyopia found in both genders.This study found no significant association between gender and types of amblyopia and anisometropic amblyopia was the most common type of amblyopia in the data collected.

News Article | December 21, 2016

STOCKHOLM, SWEDEN--(Marketwired - Dec 21, 2016) - Apica, a leading provider of comprehensive performance testing and monitoring tools, today announced its 2016 Cyber Monday Web Performance Index. The index evaluates various aspects of the web performance for the top 100 eCommerce websites in the United States. The index is based on a weighted average of critical elements that determine web performance, including how long the elements of a webpage take to load (document object model complete or DOM score), the total site rendering time and the stability and consistency of the site under heavy and light loads. The overall web performance index is an indicator of how the eCommerce industry is performing as a whole. Web performance is a primary factor in completing transactions on eCommerce sites as well as customer experience. "The Cyber Monday Index offers a view into how the top online retail websites will perform over the next year," said Marko/Whitney. "This year's overall Cyber Monday Web Performance Index was 58/100, but we had hoped that this number was closer to 75/100 with Cyber Monday 2016 sales being the highest in history. As marketers, online retailers and eCommerce professionals look to measure the overall success of the campaigns and marketing strategies during this holiday shopping season -- it is critical to also understand overall industry website performance, scalability and load capacity to understand what the shopper is experiencing." Multiple studies have demonstrated that retail site load time directly correlates to sales as every additional 100ms of load time to open a site could cost approximately one percent in sales. Below are the key findings from the 2016 index that highlight the need for better performance testing across the majority of the top 100: Top Ten eCommerce Websites are Healthy, But Rest Are Lagging Behind Expectations Scaling and Stability is a Major Issue Across the Industry Deception Through Progressive Page Loading is Key to Speed To learn more about the index methodology and the ranking of the top 100, go to the Cyber Monday Index report. About Apica Apica provides the most comprehensive cloud and mobile application performance testing and monitoring tools, the largest testing and monitoring network, and access to battle-tested performance professionals. Since 2005, Apica has been shipping solutions that bring the capabilities of much more expensive solutions to modern APM solutions. That's why global leaders such as HBO, Virgin America, JPMC and Activision have chosen Apica as their performance testing and monitoring solution that completes their DevOps initiatives. Apica is based in Stockholm, Sweden and Santa Monica, CA, with offices in London and New York. To learn more about Apica, visit

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