Osun State, Nigeria

Joseph Ayo Babalola University

Osun State, Nigeria

The Joseph Ayo Babalola University is a private Nigerian university located in Ikeji-Arakeji in Osun State, established by the Christ Apostolic Church Worldwide.The university is named after the first Spiritual leader of Christ Apostolic Church, Joseph Ayo Babalola ; it is located at the place where he was called by God to slay the Ogobungo ogre in 1928. Joseph Ayo Babalola University is a fully residential institution. Wikipedia.

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Oluba O.M.,Joseph Ayo Babalola University | Olusola A.O.,Adekunle Ajasin University | Fagbohunka B.S.,Joseph Ayo Babalola University | Chukwu Onyeneke E.,University of Benin
International Journal of Medicinal Mushrooms | Year: 2012

This study was aimed at investigating the in vivo antimalarial activity (using some biochemical indices) of crude aqueous extracts of the fruiting bodies of Ganoderma lucidum, a mushroom with well-established medicinal properties. A rodent malaria parasite, Plasmodium berghei (1 × 107), was inoculated intraperitoneally into Swiss albino mice. The test groups were administered G. lucidum extract and chloroquine (CQ, as standard drug), while the control groups were administered the same amount of distilled water by an intragastric tube once daily. The antimalarial activity of the extract was investigated from the suppressive, curative, and prophylactic effects of the extract on parasite growth. Serum aminotransferases (AST and ALT), alkaline phosphatase (ALP), and gamma glutamine transpeptidase (γ-GT) levels monitored following the 4-day suppressive test were significantly reduced, with a corresponding significant increase in the livers of mice treated with the extract compared with infected untreated mice. The results obtained from this study provide scientific justification in an animal model of malaria that an ethanolic extract of G. lucidum possesses potent antimalarial activity and also could help ameliorate the attendant Plasmodium-induced liver damage due to malarial infection. © 2012 Begell House, Inc.

Fakoya S.,Joseph Ayo Babalola University
Research Journal of Environmental Toxicology | Year: 2011

Pleurotus ostreatus is an edible mushroom rated as the second most important in production in the world after Agaricus bisporus. The local availability of substrates made it an economically viable preposition in the tropics. Sawdust of two selected tropical trees: Hog plum (Spondias mombin, L; Family: Anacardiaceae) and African nut (Pycnanthus angolensis, Welw, Warb; Family: Myristicaceae, were used as the sole substrates for the cultivation of the mushroom. The mineral composition and proximate value of the harvested fruiting bodies were determined, also the toxicological effects on experimental animals (albino rats) was studied. Results obtained showed that the mushroom compared favorably with other food items in terms of its protein quality, carbohydrate and calorific values as it ranges from 7.54±0.14-11.74±0.29%, 43.65±0.32-50.67±0.41% and 273.40±0.16-307.54±0.13 kcal g 1, respectively. The toxicological analysis through histopathological assay also revealed that there was no observable damage on the major organs of the experimental animals fed with mushroom composed diet (sample meal) and soybean composed diet (positive control). However, the organs of the experimental animals fed with protein free diet (negative control) were observed to have necrotic lesion and multifocal lymphocytic aggregates on the liver and kidney. Also, a disruption of the villi tips of the intestine was equally observed. © © 2011 Academic Journals Inc.

Aim: The spread of multidrug-resistant strains of bacteria makes it necessary to discover new classes of antibacterial and compounds that inhibit these resistant mechanisms. Hence, this study was conducted to evaluate the antimicrobial activities of Lenzites betulinus and Coriolopsis gallica extracts against some bacterial isolates of medical importance. Method: The organisms are Pseudomonas aeruginosa, Staphylococcus aureus, Proteus vulgaris, Klebsiella pneumoniae, Escherichia coli. Using agar well diffusion assay, the ethanolic, petroleum ether and aqueous extract of C. gallica was assayed against the bacterial isolates and the result showed that Petroleum ether extract of C. gallica and L. betulinus was able to inhibit P. vulgaris with inhibition zones of 26.0 mm and 20.0 mm respectively. Results: Ethanolic extract of C. gallica also inhibited P. vulgaris with inhibition zone of 22.0 mm while aqueous extract and petroleum ether of L. betulinus inhibited P. aeruginosa with inhibition zones of 20.0 mm and 23.0 mm respectively. E. coli and S. aureus were also inhibited by the aqueous and ethanolic extract of L. betulinus with zones of inhibition 15.0 mm and 26.0 mm against E. coli while 19.0 mm and 22.0 mm against S. aureus respectively. This study also showed the presence of some phytochemicals like tannins, phenolics, flavonoids, steroids, and saponin in the mushrooms with antimicrobial effects against the bacterial isolates used. Conclusion: The active components present in ethanolic, aqueous and petroleum ether extracts of C. gallica include phenolics, flavonoids, and steroids while phytochemicals obtained from L. betulinus are phenolics, tannins, flavonoids, and saponin respectively.

Idonije B.O.,Ambrose University | Festus O.,Ambrose University | Oluba O.M.,Joseph Ayo Babalola University
Research Journal of Medical Sciences | Year: 2011

Diabetes mellitus is characterized by some specific complications including diabetic nephropathy. Plasma creatinine and urea are useful clinical tools in assessing renal function, despite some limitations. In the present study, plasma glucose, creatinine and urea concentrations were determined in type 2 diabetic patients attending Irrua Specialist Hospital, Ekpoma, Edo state, Nigeria. About 80 (35 males and 45 females) diabetic patients aged between 30-70 years serving as tests and 50 (30 males and 20 females) age apparently healthy individuals of similar age bracket serving as controls were used for the study. © Medwell Journals, 2011.

Conns such as wild cocoyam [Colocasia esculenta] have potential to replace maize as a cheaper energy source in poultry rations. A feeding trial was conducted to evaluate the effects of graded levels of fermented wild cocoyam [Colocasia esculenta (L.) Schott] conn (FWCC), as substitutes for maize in the diets of broilers at the starter phase. One hundred and twenty unsexed day-old Hybro broiler chicks were randomly distributed to four dietary treatments in a Completely Randomized Design (CRD). There were 3 replicates per dietary treatment with 10 birds per replicate. Diet 1 without FWCC served as the control. Diets 2, 3 and 4 contained 10, 20 and 30% FWCC. Each of the diets represented a treatment. The experimental diets and clean drinking water were supplied ad libitum for 4 weeks (28 days) representing the starter phase of the broiler production. Result of the performance revealed significant (p<0.05) differences in feed intake, weight gain and feed conversion ratio. The economic analysis also showed that cost (N58.52) of a kilogram feed was highest (p<0.05) for the control and least (N53.10) for 30% FWCC. The least cost (Nl 01.24) of feed per kilogram weight gain (p<0.05) was obtained for birds fed 30% FWCC compared to (Nl 05.53) for the control. It was concluded that maize can economically be substituted with 30% FWCC in broiler starter diets. © 2014 Asian Network for Scientific Information.

Kehinde O.D.,Joseph Ayo Babalola University
International Journal of Applied Linguistics and English Literature | Year: 2012

“Inbetweeness”, a cardinal source of strength and weakness of the colonized writer, is an indispensable element in postcoloniality, emphasizing its hybrid nature. Leaning on contextual equivocation, to the “periphery”, seems to be an antidote to the certainty that the “centre” ennobles with evangelistic vigour. The transcendence-driven postcolony exploits the lithe structure of the novel genre to essay dismantling literary frontiers to reflect ideological vagueness and obscurity, which are antipodal to Western bourgeois lucidity. This article, against this background, explicates how Salman Rushdie and Ben Okri, build setting, plot and point-of-view to stem the tide of cultural subordination through imaginative contrarieties. © 2012, Australian International Academic Centre PTY LTD. All rights reserved.

Eludire A.A.,Joseph Ayo Babalola University
Research Journal of Applied Sciences, Engineering and Technology | Year: 2011

A number of problems associated with student academic record management include improper course registration, late release of students' results, inaccuracy due to manual and tedious calculation and retrieval difficulties/inefficiency. In most cases the data generated by academic institutions are usually created in non-delineated files for use by different departments/units within the institutions with the same data appearing on several of these files. This means that a simple change of address would have to be processed in two and probably three or four places, depending on the number of other files on which these data appears. The development of database concept is the answer to these problems where the amount of redundant data is reduced and the possibility that data contained on a file might be inaccurate because they were never updated. This paper discusses the design and implementation of a student registration and course management database application with Microsoft Access 2003. It also discusses the issues of selecting appropriate database model, interface design, system deployment and maintenance. A projection of record growth in relation to student population and system requirement was carried out in the study. Finally it discusses the applicability of the system in academic institutions. © Maxwell Scientific Organization, 2011.

Badiora A.I.,Joseph Ayo Babalola University
Journal of Applied Security Research | Year: 2014

This article provides some suggestive evidence that crime risk increases at the intersection of offender awareness and victim unawareness spaces using data from a crime survey. This is evident as 31.7% of self-reported victimization occurs more than 10 min away from the victim's home. About 78.2% of personal theft and 0.20% of burglary (both including attempts) occurred outside the victim's immediate locality. These figures reveal a stronger link between victim movement and certain types of crime. Furthermore, they presumably give evidence that while personal theft occurs frequently, burglary only occurs in rather rare and specific circumstances at some distance from the victim's home. The study therefore concludes that it is the intersection of the offender's and the victim's movements at a time and in a given place that presents the opportunity for crime to occur. The study suggests that where both victim and offender have traveled short distances and/or are locals, community-related approaches may plausibly have roles to play in preventing crime. On the contrary, cautions to strangers, warnings to travelers, and external importation of guardianship as well as situational prevention measures are more appropriate crime prevention strategies when the victim is not local. © 2014 © Taylor & Francis Group, LLC.

Okoror L.E.,Joseph Ayo Babalola University | Eniolorunda T.A.,Joseph Ayo Babalola University | Okoror O.I.,Ambrose Alli University
Asian Pacific Journal of Tropical Disease | Year: 2011

Objective: To study the virulence diversity through molecular evolution, and to provide insight on circulating antibodies. Methods: The nucleotide sequences of 18 Lassa virus genomic RNA encoding Lassa virus nucleoprotein isolates collected from different parts of the world since the identification of the Josiah strain were obtained from the GenBank and nucleotide substitution among them studied using the computer program MEGA 4. The genetic distances among strains were predicted by pairwise nucleotide differences. Results: The rate of synonymous substitution was high 5.889 per nucleotide per year and nonsynonymous was higher at 49.664. The average predicted rate of synonymous and nonsynonymous using modified Nei-Gojobori (assuming transition/transversion bias=2) was 27.9 which was taken as the genetic distance between strains. The average number of synonymous sites is 150.741 while the average number of nonsynonymous sites is 392.259. The phylogenetic tree was inferred by unweighted pairwise grouping in MEGA4 and using neighbour-joining method. The time of emergence of Lassa virus was predicted to be around January 1920. However, the first human appearance of the virus was predicted to be around May (1 959±24) months. In synonymous substitution the rate of (G-T) rare was high. The nucleotide frequencies were 0.314 (A), 0.246 (T/U), 0.204 (C) and 0.235 (G). The transition/transversion ratio k 1=14.991 (purines) and k 2=69.916 (pyrimidines). The overall transition/transversion bias R=16.662 with a total of 620 position in the final data set. These figures are far higher than an earlier study using Lassa virus glycoprotein. The nucleotide diversity were also very high using the Taijima's model in MEGA 4. Conclusions: The divergence within strains always coincides with the period of epidemic which goes to confirm that the cause of epidemic outbreak should be the emergence of new strain and also why the infection remains endemic despite circulating antibodies. A comparison with a similar study with the viral glycoprotein concludes that the glycoprotein is more suited for vaccine development. © 2011 Asian Pacific Tropical Medicine Press.

Okoror L.E.,Joseph Ayo Babalola University
Archives of Clinical Microbiology | Year: 2014

Background: Chlamydia pneumoniae causes of respiratory diseases and could also present as a secondary complications in respiratory diseases with very serious sequel. This study screen C. pneumonia in hospitalized individuals with previously known respiratory diseases. Design: The six geopolitical zones of Nigeria were sampled with stop stations at each of the zones. Males and females were stratified according to age groups since age is a possible cofounder that may immediately affect the results. Individuals with previous respiratory diseases and hospitalized served as cases while those with respiratory diseases and not hospitalized served as control 1and those without respiratory diseases were control 3. Methods: Blood samples were tested using the microimmunofluorescence assay using antigen from specimens cultured into chicken's embryonated eggs. Statistical evaluation was done using both Microsoft excel and SPSS version 13. Results: Of the 2652 patients screened for C. pneumonia IgG and IgM, using the microimmunoflourescence test, 2612 (98%) was positive. Patients with bronchitis had the highest positive result (60%) while pneumonia patients had the lowest (51%). The IgM and IgG distribution in the patients were also high. Antibody titeration among hospitalized patients was also high when compared to the two controls. Attack rate was highest in patients with sinusitis and bronchitis been lowest. Age group distribution in all the patients shows that the extreme ages had the highest distribution of antibodies especially of the IgM class. Chlamydia pneumonia infection was sexually distributed in patients with bronchitis, asthma and sinusitis. Conclusions: In conclusion Chlamydia pneumonia was responsible for the secondary complication (exacerbation) in hospitalized patients with age and sex as cofounders. This pathogenwas age and sexually distributed and this depended on the type of respiratory disease. © iMedPub.

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