Jondi Shapour University of Medical Science

Ahvāz, Iran

Jondi Shapour University of Medical Science

Ahvāz, Iran
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Lotfi Y.,University of Social Welfare and Rehabilitation Sciences | Rezazadeh N.,University of Social Welfare and Rehabilitation Sciences | Moossavi A.,Tehran University of Medical Sciences | Haghgoo H.A.,University of Social Welfare and Rehabilitation Sciences | And 6 more authors.
Auris Nasus Larynx | Year: 2017

Objective: Balance function has been reported to be worse in ADHD children than in their normal peers. The present study hypothesized that an improvement in balance could result in better cognitive performance in children with ADHD and concurrent vestibular impairment. This study was designed to evaluate the effects of comprehensive vestibular rehabilitation therapy on the cognitive performance of children with combined ADHD and concurrent vestibular impairment. Methods: Subject were 54 children with combined ADHD. Those with severe vestibular impairment (n = 33) were randomly assigned to two groups that were matched for age. A rehabilitation program comprising overall balance and gate, postural stability, and eye movement exercises was assigned to the intervention group. Subjects in the control group received no intervention for the same time period. Intervention was administered twice weekly for 12 weeks. Choice reaction time (CRT) and spatial working memory (SWM) subtypes of the Cambridge Neuropsychological Test Automated Battery (CANTAB) were completed pre- and post-intervention to determine the effects of vestibular rehabilitation on the cognitive performance of the subjects with ADHD and concurrent vestibular impairment. ANCOVA was used to compare the test results of the intervention and control group post-test. Results: The percentage of correct trial scores for the CRT achieved by the intervention group post-test increased significantly compared to those of the control group (p = 0.029). The CRT mean latency scores were significantly prolonged in the intervention group following intervention (p = 0.007) compared to the control group. No significant change was found in spatial functioning of the subjects with ADHD following 12 weeks of intervention (p. >. 0.05). Conclusion: The study highlights the effect of vestibular rehabilitation on the cognitive performance of children with combined ADHD and concurrent vestibular disorder. The findings indicate that attention can be affected by early vestibular rehabilitation, which is a basic program for improving memory function in such children. Appropriate vestibular rehabilitation programs based on the type of vestibular impairment of children can improve their cognitive ability to some extent in children with ADHD and concurrent vestibular impairment (p. >. 0.05). © 2017 Elsevier B.V.


Tahmasebi Birgani M.J.,Jondi Shapour University of Medical science | Tahmasebi Birgani M.J.,Golestan University of Medical Sciences | Behrooz M.A.,Jondi Shapour University of Medical science | Shahbazian H.,Golestan University of Medical Sciences | Shams A.,Jondi Shapour University of Medical science
Iranian Journal of Radiation Research | Year: 2012

Background: Attenuation coefficient (μ) plays an important role in calculations of treatment planning systems, as well as determination of dose distributions in external beam therapy, dosimetry, protection, phantom materials and industry. So, its exact measurement or calculation is very important. The aim of this study was to evaluate the μ in different points in the water phantom analytically as a formula, in addition to derive and parameterize it with dosimetry measurements data results. Materials and Methods: To find the attenuation coefficients at each point along the central axis of the beam in the phantom for every size of the fields, the first mathematical approach was performed for derivation of μs from percentage depth dose (PDD) formula. Then by dosimetry for different fields in different depths of water phantom, one can parameterize the obtained formula for μ in any field and depth. Results: By comparing the mathematical and dosimetry results, the parameters of the μ-expression were derived in terms of the dimension of square field in different depths. From this formula one can find the μ for any field in different depths for two energies of the Varian 2100CD linear accelerator, 6, 18MV with the statistical coefficient of determination of R2>0.98. Conclusion: The measurement of the μ in each field size and depth has some technical problems, but one can easily measure the μ for every point of central axis of the beams in any field size.


Amani R.,Jondi Shapour University of Medical science | Saeidi S.,Jondi Shapour University of Medical science | Nazari Z.,Jondi Shapour University of Medical science | Nematpour S.,Golestan University of Medical Sciences
Biological Trace Element Research | Year: 2010

It has been suggested that mood disorders and depressive status may be accompanied by lowered zinc status in the body, and adequate consumption of zinc increases a general perceived well-being. The main objective of this study was to assess the correlation between serum zinc concentrations and dietary zinc intakes with depression scores in university female students. In the first phase, Beck's depression questionnaire was applied in a random sampling of 308 selected 20-25-year-old female students (one third of total students in Ahvaz Jondi-Shapour University of Medical Sciences Golestan dormitories) to assess the major depressive disorder (MDD) scales. Then, in the second phase, 23 students who identified as having moderate and severe depression were selected as the case group, and 23 healthy age matched were chosen as the controls. Each of them completed a 12-item semiquantitative food frequency questionnaire containing the main food sources of zinc in the usual dietary patterns and also a 24-h food recall questionnaire to assure the daily zinc intakes. Daily zinc intakes were obtained by multiplying each portion size by its zinc content using food tables. A 5-ml blood sample was taken for further serum zinc status using flame atomic absorption spectrophotometry technique. Pearson's r was used to show the correlation between quantitative variables. Both daily zinc intake and serum zinc concentrations of MDD group were about two thirds of healthy index (p<0.01). Depressed individuals used to eat lower servings of red meats and chicken as the main food sources of zinc in students' usual diets (p<0.001). Consumption of other foods as the sources of zinc was not significantly different in two groups. A linear significant correlation between dietary zinc intakes and its serum levels was seen in samples (r=0.62; p<0.001) and MDD students (r=0.55; p<0.001). There was a linear inverse correlation between Beck questionnaire scores and serum zinc concentrations in all of the investigated students (r=-0.65; p<0.001) and MDD girls (r=-0.71; p<0.001). Beck questionnaire scores and diatary zinc intakes were also inversly correlated (r=-0.58; p<0.001). However, no statistical correlation was seen between these two variables inMDD cases. In depressed female students, dietary zinc intake is correlated to its serum concentrations; however, the serum zinc levels are inversely correlated to depression scales. Consumption of the main dietary sources of zinc such as red meats and chicken should be encouraged in young depressed girls. © Springer Science+Business Media, LLC 2009.


Naghashpour M.,Jondi Shapour University of Medical science | Amani R.,Jondi Shapour University of Medical science | Nematpour S.,Golestan University of Medical Sciences | Haghighizadeh M.H.,Jondi Shapour University of Medical science
Journal of the American College of Nutrition | Year: 2011

Objective: The objective of present study was to assess the relationship between the dietary intake and blood status of riboflavin and the prevalence of systemic inflammation among both depressed and nondepressed nurses. Methods: This was a cross-sectional study on 98 female clinical nurses (45 depressed and 53 nondepressed subjects). Depression status was assessed using the Beck Depression Inventory. We assessed dietary intake of riboflavin using 3-day 24-hour recalls. The serum concentrations of high-sensitive C-reactive protein (hs-CRP) were also measured. Riboflavin status was assessed as the erythrocyte glutathione reductase activity coefficient (EGRAC). Results: Marginal riboflavin deficiency was more prevalent in depressed subjects (P=0.028). The results of the dietary intake and status of riboflavin were classified to 3 tertiles of serum hs-CRP levels. In both nondepressed and depressed subjects, there was no significant difference between hs-CRP tertiles in dietary intakes of riboflavin, EGRAC, or riboflavin deficiencies. Conclusion: This study showed a higher prevalence of marginal riboflavin deficiency in depressed subjects. We found no association between dietary intake and status of riboflavin with low-grade systematic inflammation in nondepressed and depressed clinical nurses.


Jafarirad S.,Tehran University of Medical Sciences | Siassi F.,Tehran University of Medical Sciences | Harirchian M.-H.,Tehran University of Medical Sciences | Sahraian M.-A.,Tehran University of Medical Sciences | And 6 more authors.
Journal of Neurosciences in Rural Practice | Year: 2012

Background: Multiple sclerosis (MS) is an autoimmune disease whereby myelin sheath of the central nervous system is destroyed. Vitamin A is known to play a role in the immune system. It has been recognized that some metabolites of vitamin A can be used effectively to treat experimental autoimmune encephalomyelitis (EAE). Aims: The effect of vitamin A as retinyl palmitate on T-cell proliferation in MS patients. Setting and Design: This study is a double blind clinical trial of two test groups over a period of 6 months. Materials and Methods: Thirty five multiple sclerosis (MS) patients were divided into two groups. One group received 25,000 IU/day vitamin A (as retinyl palmitate) and the other group were administered a placebo. The peripheral blood mononuclear cells (PBMCs) were separated and stimulated with myelin oligodendrocyte glycoprotein (MOG) and phytohemagglutinin (PHA) before and after the trial period. BrdU calorimetric assay was performed to measure cell proliferation. Statistical Analysis: Analysis of covariance (ANCOVA) and paired t-test were used to analyze the data. Results: Observations showed statistical significant differences in the reduction of cell proliferation in the presence of MOG and fetal calf serum (FCS) in the culture medium, between patients receiving vitamin A and the placebo (P = 0.046). Although, this difference was not significant between the two vitamin A and placebo groups in MOG treatment with human serum, a decrease was observed in the group of patients taking vitamin A supplements (P = 0.019). Phytohemagglutinin did not cause any change in cell proliferation between the two groups. Conclusion: The results suggest supplementation with retinyl palmitate in patients with MS reduce MOG stimulatory effects on T-cells.


Nasri H.,Isfahan University of Medical Sciences | Beladmousavi S.S.,Jondi Shapour University of Medical science | Shahbazian H.,Jondi Shapour University of Medical science | Shayanpour S.,Jondi Shapour University of Medical science | Rafian-Kopaiee M.,Sharkord University of Medical science
Journal of Babol University of Medical Sciences | Year: 2016

BACKGROUND AND OBJECTIVE: Hepatitis B virus (HBV) reactivation is a major risk factor for hepatic dysfunction, acute or chronic hepatitis, cirrhosis, or hepatocellular carcinoma after kidney transplantation (KTP). The present article summarizes some of published articles about prevention of HBV reactivation in renal transplant recipients METHODS: Many articles published in English language as full-text manuscripts reviewed in a variety of sources such as Scopus, Pub Med and Google Scholar with key words of hepatitis B and kidney transplantation to collect current data about this issue. FINDINGS: The risk of reactivation of HBV followingKTP is related to the status of serologic markers of HBV at the time of KTP.KTP candidate patients who are hepatitis B surface antigen (HBsAg) positivehave higher risk for reactivation especially those who are hepatitis B e antibody positive or have high levels of HBV DNA in serum. Lamivudine has been most extensively used for prevention of HBV reactivation, but it is associated with a high rate of drug resistance.It seems that the optimal antiviral agent for prevention of HBV reactivation is entecavir which is associated with the lowest risk of drug resistance,however lamivudine-resistant HBV is less sensitive to entecavir. The preferred antiviral agent for lamivudine-resistant HBV is tenofovir which should be added to lamivudine rather than stopping lamivudine. It is reported that combination therapy in this sitting may reduce the development of resistance to the second drug. CONCLUSION: There is sufficient evidence to recommend routine antiviral prophylaxis for all HBsAg-positive patients who are undergoing kidney transplantation. © 2016, Babol University of Medical Sciences. All rights reserved.


Jafarirad S.,Tehran University of Medical Sciences | Siassi F.,Tehran University of Medical Sciences | Harirchian M.-H.,Tehran University of Medical Sciences | Amani R.,Jondi Shapour University of Medical science | And 2 more authors.
Iranian Red Crescent Medical Journal | Year: 2013

Background: Vitamin A has different functions in the body and after being converted to acid form; it can play many roles in immune system regulation. Therefore, this vitamin can be used as a supplement in the treatment of diseases, such as cancer and autoimmune diseases. Vitamin A is a fat-soluble compound and its long-term consumption in high doses can have some adverse effects. Objective: The objective of this survey was to investigate the possible complications and find solutions to minimize the adverse effects. Patients and Methods: This study was a double blind randomized clinical trial. In main study, vitamin A (as retinyl palmitate) was given to 35 multiple sclerosis (MS) patients in order to regulate their immune system with a dose of 25000 IU/day for a period of six months. To investigate the possible biochemical complications, lipid profiles, fasting blood sugar (FBS), liver enzymes, and C-reactive protein (CRP) were tested. Results: Vitamin A did not have a significant difference in lipid profiles, FBS and liver enzymes between the two groups receiving vitamin A and the placebo, but CRP increased in patients who were taking vitamin A, 1.65 ± 0.43 (mg/L) and 2.88 ± 0.67, (Mean ± SEM), before and after the intervention respectively (P = 0.029), and statistical analysis showed significant differences with the group receiving placebo (P = 0.011) and CRP level in vitamin A group was 1.3 mg/L more than the placebo group after intervention (P = 0.011). Conclusions: Considering that no significant difference was found in the proven vitamin A side effects, due to the increase in CRP, frequent clinical and biochemical controls are required along with vitamin A supplementation.


Yaghoobi R.,Jondi Shapour University of Medical science | Maraghi S.,Jondi Shapour University of Medical science | Bagherani N.,Jondi Shapour University of Medical science | Rafiei A.,Jondi Shapour University of Medical science
Korean journal of ophthalmology : KJO | Year: 2010

Leishmaniasis is a parasitic disease caused by Leishmania species and is classified into three forms; cutaneous, mucocutaneous, and visceral. The eyelid is a rare site involved by leishmaniasis and only makes up 2.5% of cases with cutaneous leishmaniasis (CL). Although CL can affect both upper and lower lids on either their outer or inner aspects, the lateral canthus is most often affected. The most common aspect of lid leishmaniasis is chalazion-like lesions but ulcerous, phagedenic, cancer-like forms, and unilateral chronic granulomatous blepharitis may be observed. When the lid is involved, the disease is usually self-limiting; healing usually takes up to one year, hence early diagnosis and treatment are important. The diagnosis is based on a high index of suspicion regarding the endemicity of the disease in the region. Response to treatment in lid CL cases is quite satisfactory. In this article, we report nine cases of lid leishmaniasis with satisfactory responses to intralesional meglumine antimoniate.


PubMed | Jondi Shapour University of Medical science
Type: Journal Article | Journal: Iranian journal of nursing and midwifery research | Year: 2013

Bed sore is one of the main problems for people confined to bed for long time and cannot move. According to the fact that prevention is easier and cheaper than therapy, in this study the effect of fish oil ointment on the improvement of first stage bed sore was assessed.This study was carried out on two groups with 30 patients that had bed sore on shoulders, sacrum or heel. In the intervention group patients position was changed every 2-3 hours and the bed sore was washed with water and cotton-wool and fish oil with thickness of 2-3 mm was applied on the place of sore. This method was used for seven days. If they improved, the method was stopped in the first days of procedure. At the end of seven days, again the first day checklist was completed, and it was compared to the questionnaire of the two groups, and analyzed separately according to the daily changes of intervention and control group.There was statistically significant difference between the average of changes in the size of sore of the study group and control group (p < 0.002). The time average of improvement in the intervention group was less than control group.Local use of fish oil could increase the improvement of first stage bed sore and increase in vessels, blood and oxygen supply of the place of sore.


PubMed | Jondi Shapour University of Medical Science and Shahid Chamran University
Type: Journal Article | Journal: Iranian biomedical journal | Year: 2016

Coronary artery disease (CAD) is a multifactorial and heterogenic disease. Recently, genome-wide association studies have reported that rs1333040 (C/T) and rs1004638 (A/T) single nucleotide polymorphisms (SNPs) in the 9p21 locus have very strong association with CAD. This study aimed to examine these associations in Southwest of Iran.Blood samples were collected from 200 CAD patients and 110 healthy individuals with no CAD. The association of two SNPs with CAD was evaluated by PCR and restriction fragment length polymorphism.Chi-square test showed no association between rs1333040 SNP and CAD (X2: 4.66, df: 2, P=0.09). Also, there was no association between rs1004638 SNP and CAD (X2: 0.27, df: 2, P=0.88).No association was observed between rs1333040 and rs1004638 SNPs in the 9P21 region and CAD in Southwest of Iran.

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