Johnson, NJ, United States
Johnson, NJ, United States

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Pappas A.,Johnson and Johnson Consumer Companies Inc. | Fantasia J.,Johnson and Johnson Consumer Companies Inc. | Chen T.,Johnson and Johnson Consumer Companies Inc.
Dermato-Endocrinology | Year: 2013

This study was conducted to compare lipid components of sebum from persons from three ethnic backgrounds-Caucasian, African American and Northern Asian. Men and women with no acne in two age groups (18-25 y and 35-45 y) were recruited. Skin surface hydration (SkiCon 200EX and NovaMeter), barrier function (Delfin VapoMeter), highresolution clinical imaging, self-assessments and two pairs of sebutapes on the forehead that extracted the lipids on the surface of their skin were used. Significant differences (p 0.05) in skin hydration between African Americans and Caucasians in both age groups were noted, with the order from highest to lowest absolute values: African American - Northern Asian - Caucasian. Transepidermal water loss (TEWL) measurements demonstrated that African Americans and Caucasians were significantly different (p 0.05), with the trend being the inverse of the hydration trend-Caucasian - Northern Asian - African American, which would indicate better barrier function for African Americans with a lower TEWL. African American women had more total lipid production than Northern Asian or Caucasian women. When analyzingthe three lipid classes (free fatty acids, triglycerides and wax esters), the trend became significant (p 0.05) in the wax ester fraction when directly comparing African Americans with Caucasians. Additionally, six lipids were identified in the wax ester fractions that were significantly different in quantity (p 0.05) between African Americans and Caucasians. These results identified significant differences in sebaceous lipid profiles across ethnic groups and determined that the differences correlated with skin barrier function.© 2013 Landes Bioscience.

Stamatas G.N.,Johnson and Johnson Sante Beaute France | Tierney N.K.,Johnson and Johnson Consumer Companies Inc.
Pediatric Dermatology | Year: 2014

Pediatricians and parents report diaper dermatitis (DD) to be one of the most common skin diseases that affects almost every child at some point during the early months and years of life. Diapered skin is exposed to friction and excessive hydration, has a higher pH than nondiapered skin, and is repeatedly soiled with feces that contains enzymes with high irritation potential for the skin. The combination of these factors frequently results in skin damage, leading to visible erythematous lesions that can be irritating and painful to the child. Behavioral changes such as increased crying and agitation and changes in eating and sleeping patterns indicate emotional distress. Appropriate skin care can help to prevent the occurrence of DD and to speed up the healing of affected skin. This includes frequent diaper changes and aeration, gentle cleansing, and the use of a barrier cream. Mild to moderate cases usually resolve after a few days of following this routine, but the use of harsh cleaning products can exacerbate DD. © 2013 Wiley Periodicals, Inc.

Mindell J.A.,Children's Hospital of Philadelphia | Cook R.A.,Johnson and Johnson Consumer Companies Inc. | Nikolovski J.,Johnson and Johnson Consumer Companies Inc.
Sleep Medicine | Year: 2015

Objective: This study sought to characterize sleep patterns and sleep problems in a large sample of women across all months of pregnancy. Methods: A total of 2427 women completed an Internet-based survey that included the Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale, vitality scale of the Short Form 36 Health Survey (SF-36), Insomnia Severity Index (ISI), Berlin questionnaire, International Restless Legs Syndrome (IRLS) question set, and a short version of the Pregnancy Symptoms Inventory (PSI). Results: Across all months of pregnancy, women experienced poor sleep quality (76%), insufficient nighttime sleep (38%), and significant daytime sleepiness (49%). All women reported frequent nighttime awakenings (100%), and most women took daytime naps (78%). Symptoms of insomnia (57%), sleep-disordered breathing (19%), and restless legs syndrome (24%) were commonly endorsed, with no difference across the month of pregnancy for insomnia, sleep-disorder breathing, daytime sleepiness, or fatigue. In addition, high rates of pregnancy-related symptoms were found to disturb sleep, especially frequent urination (83%) and difficulty finding a comfortable sleep position (79%). Conclusions: Women experience significant sleep disruption, inadequate sleep, and high rates of symptoms of sleep disorder throughout pregnancy. These results suggest that all women should be screened and treated for sleep disturbances throughout pregnancy, especially given the impact of inadequate sleep and sleep disorders on fetal, pregnancy, and postpartum outcomes. © 2014 Elsevier B.V.

Johnson and Johnson Consumer Companies Inc. | Date: 2012-04-11

The present application features a device having a barrier membrane contacting surface, the device containing: a power source; a first conductive electrode (140); a second conductive electrode (240); and a carrier (120); wherein the power source is in electric communication with the first conductive electrode and the second conductive electrode, wherein the first conductive electrode and the second conductive electrode are in ionic communication with the carrier, and wherein the carrier is in communication with the barrier membrane contacting surface.

Johnson and Johnson Consumer Companies Inc. | Date: 2013-02-12

Compositions and methods for inducing hair growth and improving hair quality utilizing extracts of blackberry in an amount effective to induce hair growth when applied topically to an area of the skin on which hair growth is desired.

Johnson and Johnson Consumer Companies Inc. | Date: 2011-08-17

The present invention features a device having a barrier membrane contacting surface, the device containing: a power source; a first conductive electrode; a second conductive electrode; and a reservoir; wherein said power source is in electric communication with said first conductive electrode and said second conductive electrode, wherein said first conductive electrode and said second conductive electrode are arranged such that they are both capable of being in ionic communication with a carrier upon the inclusion of said carrier to said reservoir; and the use thereof.

Johnson and Johnson Consumer Companies Inc. | Date: 2011-05-04

The present invention relates to a composition comprising an NFB-inhibitor and a non-retinoid collagen promoter.

Johnson and Johnson Consumer Companies Inc. | Date: 2011-05-11

This invention relates to a novel composition useful for the treatment of skin, and more particularly, to a composition containing benzoyl peroxide for treating acne while providing enhanced delivery and low level of irritation to skin.The composition comprises a mixture of a co-solvent (preferably volatile polysiloxanes) and an ester (like for instance waxes, shea butter, cetyl stearate, sunflowerseedcetyl lactate).

Russell M.,Johnson and Johnson Consumer Companies Inc.
Nutrients | Year: 2012

Vitamin D3 has been called the "sunshine" vitamin since the formation of vitamin D is mediated by exposure to sunlight. Vitamin D3 is linked to many health benefits, however serum levels of vitamin D3 have been decreasing over the last few decades and the lower levels of vitamin D3 may have consequences on normal physiology. We investigated the association between serum 25-hydroxyvitamin D (25(OH)D) levels and stratum corneum conductance as well as the effect of topical application of cholecalciferol (vitamin D3) on dry skin. Eighty three subjects were recruited and blood serum levels and skin conductance measurements were taken after a one week washout. A correlation was observed between vitamin D levels and skin moisture content, individuals with lower levels of vitamin D had lower average skin moisture. Subsequently, a 3-week split leg, randomized, vehicle controlled clinical study was conducted on a subset of 61 of the above individuals who were identified with non-sufficient vitamin D serum levels. Topical supplementation with cholecalciferol significantly increased measurements of skin moisturization and resulted in improvements in subjective clinical grading of dry skin. Taken together our finding suggest a relationship between serum vitamin D3 (25(OH)D) levels and hydration of the stratum corneum and further demonstrate the skin moisture benefit from topical application of vitamin D3. © 2012 by the authors; licensee MDPI, Basel, Switzerland.

Capone K.A.,Johnson and Johnson Consumer Companies Inc. | Dowd S.E.,Research and Testing Laboratories LLC | Stamatas G.N.,Johnson and Johnson Sante Beaute France | Nikolovski J.,Johnson and Johnson Consumer Companies Inc.
Journal of Investigative Dermatology | Year: 2011

Within days after birth, rapid surface colonization of infant skin coincides with significant functional changes. Gradual maturation of skin function, structure, and composition continues throughout the first years of life. Recent reports have revealed topographical and temporal variations in the adult skin microbiome. Here we address the question of how the human skin microbiome develops early in life. We show that the composition of cutaneous microbial communities evolves over the first year of life, showing increasing diversity with age. Although early colonization is dominated by Staphylococci, their significant decline contributes to increased population evenness by the end of the first year. Similar to what has been shown in adults, the composition of infant skin microflora appears to be site specific. In contrast to adults, we find that Firmicutes predominate on infant skin. Timely and proper establishment of healthy skin microbiome during this early period might have a pivotal role in denying access to potentially infectious microbes and could affect microbiome composition and stability extending into adulthood. Bacterial communities contribute to the establishment of cutaneous homeostasis and modulate inflammatory responses. Early microbial colonization is therefore expected to critically affect the development of the skin immune function. © 2011 The Society for Investigative Dermatology.

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