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Pardhe N.D.,Mahatma Gandhi Dental College and Hospital | Bhagalia S.,Jodhpur Dental College and Hospital | Nayak P.A.,Mahatma Gandhi Dental College and Hospital | Sireesha S.K.,Government of Rajasthan
BMJ Case Reports | Year: 2013

Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare central jaw carcinoma derived from odontogenic epithelial remnants. When the tumour arises in an existing cyst, it may be difficult to recognise early PIOSCC and carry out necessary treatment. We report a case diagnosed in a 50-year-old man where timely intervention was delayed and prognosis was affected and the case diagnosed eventually by comprehensive clinical, radiological and histopathological examination. Copyright 2013 BMJ Publishing Group. All rights reserved.

Singh M.,Jodhpur Dental College and Hospital | Nayak M.,Vyas Dental College and Hospital | Solanki J.,Vyas Dental College and Hospital | Gupta S.,Vyas Dental College and Hospital | Singh A.,Vyas Dental College and Hospital
Malaysian Journal of Medical Sciences | Year: 2015

The loss or disfigurement of a body parts specially that pertaining to the face has a deep psychological and social impact on the patient. After enucleation, evisceration or exteneration of the eye, the aim of an ocular prosthesis should be to restore the natural appearance, install confidence and a sense social acceptability in the patient. Custom made prosthesis has several advantages over the stock eye prosthesis. This article illustrates rehabilitation of the enucleated right eye of a patient with a custom made ocular prosthesis. © Penerbit Universiti Sains Malaysia, 2015.

Saawarn S.,Peoples Dental Academy | Astekar M.,JKK Nataraja Dental College and Hospital | Dhakar N.,Darshan Dental College and Hospital | Gomateshwar Sagari S.,Jodhpur Dental College and Hospital
The Scientific World Journal | Year: 2012

Background. Cyclin D1 regulates the G1 to S transition of cell cycle. Its deregulation or overexpression may lead to disturbance in the normal cell cycle control and tumour formation. Overexpression of cyclin D1 has been reported in various tumors of diverse histogenesis. This case control retrospective study was carried out to study the immunohistochemical reactivity and expression of cyclin D1 and its association with site, clinical staging, and histopathological differentiation of oral squamous cell carcinoma (OSCC). Methods. Forty formalin-fixed paraffin-embedded tissue blocks of biopsy specimens of oral squamous cell carcinoma were immunohistochemically evaluated for expression of cyclin D1. Results. Cyclin D1 expression was seen in 45% cases of OSCC. It did not correlate with site and clinical staging. Highest expression was seen in well-differentiated, followed by moderately differentiated, and poorly differentiated squamous cell carcinomas, with a statistically significant correlation. Conclusion. Cyclin D1 expression significantly increases with increase in differentiation. Copyright © 2012 Swati Saawarn et al.

Manjunatha B.S.,K M Shah Dental College and Hospital | Harsh A.,Dr Sampurnanand Medical College and Hospital | Purohit S.,Jodhpur Dental College and Hospital | Naga M.V.,K M Shah Dental College and Hospital
Journal of Cancer Research and Therapeutics | Year: 2015

Adenomatoid odontogenic tumor (AOT) is a relatively uncommon benign lesion of odontogenic origin mainly affecting females in second decade of life, having a predilection for the anterior region of the maxilla. Histologically, it is composed of odontogenic epithelium in a variety of histopathological patterns in a mature, fibrous connective tissue stroma and characterized by slow but progressive growth. Very few cases of AOT associated with a dentigerous cyst have been reported in the literature. PubMed and Medline data showed a total of 11 cases of AOT associated with a dentigerous cyst in the literature. We present an additional case of an AOT arising from a dentigerous cyst around the crown of an unerupted upper canine in a 20-year-old female, which was clinically diagnosed as a dentigerous cyst. Histologically, the case showed proliferation of odontogenic epithelium in the form of whorls and islands typical of AOT associated with dentigerous cyst appearing thin reduced enamel like epithelium lining the cystic cavity, described previously. However, it is unclear whether this entity has a more aggressive potential.

Purohit S.,Jodhpur Dental College and Hospital | Manjunatha B.S.,Taif University | Dagrus K.,K M Shah Dental College and Hospital | Harsh A.,Dr Sampurnanand Medical College and Hospital
Journal of Experimental Therapeutics and Oncology | Year: 2016

Mucoepidermoid carcinoma (MEC) is the malignant salivary gland neoplasm chiefly occurred in minor salivary gland. One of the rare variant of MEC is intraosseous variant found in the jaws known as central mucoepidermoid carcinoma. Presently in this case report, we described a 28-year-old male diagnosed with central low grade mucoepidermoid carcinoma subsequently with the presence of asymptomatic swelling with a history of trauma. Clinically mimicking a cystic lesion and radiographically gives an idea of mixed radio-opaque radiolucent lesion which creates a confusion to render a final diagnosis. The site, duration and history of the case are uncommon for the occurrence of intra-osseous malignant lesion of salivary glands. Present case adds new dimensions to the present knowledge about the clinical and radiographical picture that a central mucoepidermoid carcinoma can mimic. © 2016 Old City Publishing, Inc.

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