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Yan J.-K.,Shandong University | Wang Y.-Z.,Jinan Nursing Vocational College | Tian C.,Shandong University | Liu S.-D.,Shandong University | And 6 more authors.
Central European Journal of Medicine | Year: 2014

Objective. The aim of this study was to examine the expression patterns of CEACAM5 in prostatic non-neoplastic and neoplastic lesions and further investigate its relationship with tumor microvessel density(MVD) and lymphatic vessel density(LVD). Methods. CEACAM5 expression was detected using immunohistochemical staining in a serial sections of the benign prostatic hyperplasia (BPH), prostate intraepithelial neoplasia (PIN) and prostate carcinoma (PCa) lesions. MVD and LVD were quantified in CEACAM5 positive areas by dual-labelling with CD34 and D2-40 respectively. Results. Both PIN and PCa had significantly higher expression for CEACAM5 than BPH which has no positive expression for CEACAM5(P<0.05). In PIN and PCa, CEACAM5 staining showed different expression patterns in terms the of most of membranous staining for PIN, less membranous staining and more cytoplasmic staining for PCa. MVD results showed that PCa and PIN had more angiogenesis than BPH tissue. The value of MVD in PCa tissue was correlated with tumor Gleason grading (P<0.05). LVD results showed that neoplastic lesions had more lymphangiogenesis than non-neoplastic lesion. Conclusion. CEACAM5 had different expression patterns in prostatic non-neoplastic and neoplastic lesions, and these various expression patterns may be correlated with tumor progression through promoting tumorous angiogenesis or lymphangiogenesis. © 2014 Versita and Springer-Verlag.

Hua Z.,Jinan Nursing Vocational College | Guodong L.,Peoples Bank of China | Tengfei Z.,China Construction Seventh Engineering Division Corporation
Proceedings - 2013 6th International Conference on Business Intelligence and Financial Engineering, BIFE 2013 | Year: 2014

This paper present it is necessary to develop low carbon economy in China. Additionally, considering the current development status of the low carbon economy in China, this paper puts forward relevant policy suggestions on China's low carbon economy in three aspects of legal measures, economic measures and administrative measures. © 2013 IEEE.

Wang J.,Shandong Jiaotong University | Zhuang Y.,Jinan Nursing Vocational College
Advanced Materials Research | Year: 2012

For industrial robot manipulator system, PD control theory is extensively used in the dynamic characteristics controlling. A PD robust controller is introduced to optimize the stability and convergence of traditional PD controller and avoid excess initial driving torque for two-link industrial manipulator system. By the co-simulation on ADAMS and Matlab/Simulink, the paper designs a PD robust controller under given upper bound disturbance and completes track control and driving torque trial. Through result comparison and analysis, the superiority of the PD robust controller for two-link manipulator is verified. © (2012) Trans Tech Publications.

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