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Changchun, China

Jilin University is a leading national research university under the direct jurisdiction of China's Ministry of Education.Located in Changchun, the capital city of Jilin Province in Northeast China, the university has seven campuses in six districts which are home to thirty-nine colleges covering thirteen academic disciplines, including philosophy, international relations, economics, law, literature, education, history, science, engineering, agriculture, medicine, management, and military science. The University has thirteen disciplinary areas, six national key laboratories, and seven national bases for the development of basic science. Other resources include five research bases for humanities and social science, eleven key laboratories sponsored by the Ministry of Education and eleven by other ministries of Chinese government.Jilin University is one of the most prestigious "Top 10" universities in China, and has several research projects in automobile engineering, chemistry, computer science, electrical engineering and biology. JLU also provides undergraduate and graduate programs in law, literature, philosophy, medicine and veterinary science. It is one of the key universities involved in China's Project 985, Project 211 and Project 2011.Jilin University is a comprehensive and national key university. JLU offers a variety of degree programs. It has now 115 undergraduate programs, 192 Master's degree program, 105 doctoral degree programs, and seventeen post-doctoral programs. In 2003 the university enrolled 59,000 full-time students, including more than 10,000 graduate students. At present there are 6,540 faculty members, with twenty members of Chinese Academy of science and Chinese Academy of Engineering, 1270 full professors, and 1652 associate professors. Wikipedia.

Gao J.-M.,Northwest University, China | Yang S.-X.,Zhejiang Agriculture And forestry University | Qin J.-C.,Jilin University
Chemical Reviews | Year: 2013

Researchers survey the chemical and biological literature regarding the isolation, structure elucidation, biological activities, biosynthesis, and chemical synthesis of azaphilone derivatives from nature. The general methods for the synthesis of some natural azaphilone-like scaffolds are also discussed. Citrinin produced by several fungal species of genera Penicillium, Monascus, and Aspergillus, is widely considered as a hazardous contaminant of foods and feeds. A number of various derivatives of the citrinin family have been isolated from different P. citrinum strains and two Aspergillus species. The derivatives can be classified into four different categories on the basis of the degree of polymerization of the citrinin core, including monomeric citrinin congeners 2-6 and decarboxydihydrocitrinin.

Tian P.,Jilin University
Chemical Society Reviews | Year: 2010

Computational protein design is becoming more and more important in both understanding the fundamental biological roles of proteins and facilitating their utilization in biotechnology. Based upon the significant progress in our understanding of protein folding, development of efficient sequence and conformational search algorithms and accurate scoring functions, and ever increasing computational resources, great progress has been made in design of single domain soluble proteins. There are also reports of membrane protein design, albeit very limited. This tutorial review will give a brief introduction, the state of the art, and future prospects and implications of protein design in improving healthcare and environment. The interplay between protein design, molecular simulations and experiments will be presented to emphasize the interdisciplinary nature of the field. © The Royal Society of Chemistry 2010.

Liu Z.-Q.,Jilin University
Chemical Reviews | Year: 2010

Researchers conducted investigations to develop chemical methods for evaluating antioxidant ability. The researchers also introduced some biological materials as experimental materials in evaluating antioxidant capacity chemically. The first scheme demonstrated the mode for exploring antioxidant capacity who basis contained four factors. Substrates were compounds that were susceptible to oxidation and the microenvironment imitated the biological surroundings. The applications of erythrocytes, DNA, and LDL combined the substrate with the microenvironment. Treatment of the results from these biological samples with chemical kinetics revealed molecular information on the biological samples. Metal ions, and other oxidants were also applied to initiate the oxidation of chemical agents or biological samples to imitate oxidative stress, radical initiators, and UV radiation.

Liu Z.-Q.,Jilin University
Chemical Reviews | Year: 2012

The chemistry, biosynthesis, analysis, and tonic effects of ginsenosides were reviewed to gather information about ginseng as a resource for natural antioxidants. Investigations revealed that anticarcinogenic, immunomodulatory, anti-inflammatory, antiallergic, antiatherosclerotic, antihypertensive, antidiabetic, antistress, and anticancer activities of ginseng were due to the action of ginsenosides. The pharmacological action of ginseng was related to the abilities of ginsenosides to regulate enzyme expression, and more individual ginsenosides were needed for comparing pharmacological activity and for exploring the structure-activity relationships. Some chemicals, such as CO 2 and jasmonic acid were found to increase the contents of ginsenosides and other antioxidants. It was also observed that the treatment of Panax notoginseng with 2-hydroxyethyl jasmonate in a bioreactor increased the activities of protopanaxdiol 6-hydroxylase and Rd glucosyltransferase and changed the ratios of Rb/Rg and Rb1/Rd.

Zou X.,Jilin University | Zhang Y.,Beihang University
Chemical Society Reviews | Year: 2015

Sustainable hydrogen production is an essential prerequisite of a future hydrogen economy. Water electrolysis driven by renewable resource-derived electricity and direct solar-to-hydrogen conversion based on photochemical and photoelectrochemical water splitting are promising pathways for sustainable hydrogen production. All these techniques require, among many things, highly active noble metal-free hydrogen evolution catalysts to make the water splitting process more energy-efficient and economical. In this review, we highlight the recent research efforts toward the synthesis of noble metal-free electrocatalysts, especially at the nanoscale, and their catalytic properties for the hydrogen evolution reaction (HER). We review several important kinds of heterogeneous non-precious metal electrocatalysts, including metal sulfides, metal selenides, metal carbides, metal nitrides, metal phosphides, and heteroatom-doped nanocarbons. In the discussion, emphasis is given to the synthetic methods of these HER electrocatalysts, the strategies of performance improvement, and the structure/composition-catalytic activity relationship. We also summarize some important examples showing that non-Pt HER electrocatalysts could serve as efficient cocatalysts for promoting direct solar-to-hydrogen conversion in both photochemical and photoelectrochemical water splitting systems, when combined with suitable semiconductor photocatalysts. This journal is © The Royal Society of Chemistry.

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