Changchun, China
Changchun, China

Jilin University is a leading national research university under the direct jurisdiction of China's Ministry of Education.Located in Changchun, the capital city of Jilin Province in Northeast China, the university has seven campuses in six districts which are home to thirty-nine colleges covering thirteen academic disciplines, including philosophy, international relations, economics, law, literature, education, history, science, engineering, agriculture, medicine, management, and military science. The University has thirteen disciplinary areas, six national key laboratories, and seven national bases for the development of basic science. Other resources include five research bases for humanities and social science, eleven key laboratories sponsored by the Ministry of Education and eleven by other ministries of Chinese government.Jilin University is one of the most prestigious "Top 10" universities in China, and has several research projects in automobile engineering, chemistry, computer science, electrical engineering and biology. JLU also provides undergraduate and graduate programs in law, literature, philosophy, medicine and veterinary science. It is one of the key universities involved in China's Project 985, Project 211 and Project 2011.Jilin University is a comprehensive and national key university. JLU offers a variety of degree programs. It has now 115 undergraduate programs, 192 Master's degree program, 105 doctoral degree programs, and seventeen post-doctoral programs. In 2003 the university enrolled 59,000 full-time students, including more than 10,000 graduate students. At present there are 6,540 faculty members, with twenty members of Chinese Academy of science and Chinese Academy of Engineering, 1270 full professors, and 1652 associate professors. Wikipedia.

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The present invention provides an adulterated peanut oil detector and an adulterated peanut oil detection method, and pertains to the technical domain of product analysis. The detector comprises a casing, a LCD and Return key, Enter key, Up key, Down key, a power switch, a power socket, and a USB interface arranged on the casing, and a microprocessor and a power supply unit mounted in the casing and electrically connected to the components on the casing, wherein, a module cover is arranged on the top surface of the casing, and a pretreatment module and a detection module are mounted in the space under the module cover. The pretreatment module comprises a heating body and cuvette slots, and the detection module comprises an axial fan, a radiating plate, a refrigerating plate, and cuvette slots. The detection method comprises sample preheating procedure and slow refrigeration procedure. The detector and method provided in the present invention can quickly and easily detect whether the peanut oil sample is adulterated and the percentage of adulteration, and is applicable to quick on-spot detection of rapeseed oil, sunflower oil, maize oil, cotton oil, palm oil, and soybean oil, etc. admixed in peanut oil.

The present invention provides an adulterated peanut oil detector and an adulterated peanut oil detection method, and pertains to the technical domain of product analysis. The detector comprises a casing, a LCD and Return key, Enter key, Up key, Down key, a power switch, a power socket, and a USB interface arranged on the casing, and a microprocessor and a power supply unit mounted in the casing and electrically connected to the components on the casing, wherein, a module cover is arranged on the top surface of the casing, and a pretreatment module and a detection module are mounted in the space under the module cover. The pretreatment module comprises a heating body and cuvette slots, and the detection module comprises an axial fan, a radiating plate, a refrigerating plate, and cuvette slots. The detection method comprises sample preheating procedure and slow refrigeration procedure. The detector and method provided in the present invention can quickly and easily detect whether the peanut oil sample is adulterated and the percentage of adulteration, and is applicable to quick on-spot detection of rapeseed oil, sunflower oil, maize oil, cotton oil, palm oil, and soybean oil, etc. admixed in peanut oil.

Cheng M.,Jilin University | Cheng M.,CAS Beijing Institute of Applied Physics And Computational Mathematics
Zeitschrift fur Angewandte Mathematik und Physik | Year: 2017

We are concerned with the 3-D compressible Hall-magnetohydrodynamic system with a time-periodic external force in a periodic domain, and establish the existence of a strong time-periodic solution under some smallness and symmetry assumptions by adapting a new approach. The basic idea of the proof is the following. First, we prove the existence of a time-periodic solution to the linearized system by applying the Tychonoff fixed point theorem combined with the energy method and the decay estimates. From the details of the proof, we see that the initial data of the time-periodic solution to the linearized system lies in some convex hull. Then, we construct a set-value function, such that the fixed point of this function is a time-periodic solution of the compressible Hall-magnetohydrodynamic system. The existence of the fixed point is obtained by the Kakutani fixed point theorem. Moreover, we establish the uniqueness of the time-periodic solution and the existence of the stationary solution. © 2017, Springer International Publishing.

Feng W.,Jilin University | Wang Z.,Jilin University | Zhang W.,Jilin University
Langmuir | Year: 2017

Understanding the relationship between polymer chain conformation as well as the chain composition within the single crystal and the mechanical properties of the corresponding single polymer chain will facilitate the rational design of high performance polymer materials. Here three model systems of polymer single crystals, namely poly(ethylene oxide) (PEO), polyethylene (PE), and nylon-66 (PA66) have been chosen to study the effects of chain conformation, helical (PEO) versus planar zigzag conformation (PE, PA66), and chain composition (PE versus PA66) on the mechanical properties of a single polymer chain. To do that, steered molecular dynamics simulations were performed on those polymer single crystals by pulling individual polymer chains out of the crystals. Our results show that the patterns of force-extension curve as well as the chain moving mode are closely related to the conformation of the polymer chain in the single crystal. In addition, hydrogen bonds can enhance greatly the force required to stretch the polymer chain out of the single crystal. The dynamic breaking and reformation of multivalent hydrogen bonds have been observed for the first time in PA66 at the single molecule level. © 2017 American Chemical Society.

Dong J.,Jilin University | Li B.,Jilin University | Bao Q.,Jilin University
Journal of Contaminant Hydrology | Year: 2017

Mg(OH)2 dissolves slowly and can provide a long-term source of alkalinity, thus a promising alternative reagent for the in situ remediation of heavy metal polluted groundwater. However, the application of Mg(OH)2 on in situ reactive zone (IRZ) for heavy metal polluted groundwater has never been investigated. In this study, the behaviors of heavy metals in a Mg(OH)2 IRZ were monitored for 45 d. The heavy metals show a sequential precipitation by modified Mg(OH)2 due to the difference of Ksp. Column tests were conducted to investigate the temporal and spatial distribution of heavy metals in Mg(OH)2 IRZ and evaluate the stabilization effect for multi-heavy metal polluted groundwater. Experimental results indicate that there exist interactions between different heavy metals, and their zoning distribution is attributed either to the competitive adsorption onto porous media (control column) or to the sequential precipitation of heavy metal ions (IRZ column). In contrast with the control column, heavy metal contaminated area in Mg(OH)2 IRZ significantly shrinks. According to the chemical speciation analysis, when water containing Pb(II), Cd(II) and Cr(III) flows through Mg(OH)2 IRZ, exchangeable fraction of total concentration significantly reduce and the proportion of carbonate and Fe/Mn oxides fraction increase, indicating the decrease of their mobility and toxicity. © 2017 Elsevier B.V.

Li S.,Jilin University | Sun A.,Jilin University
IOP Conference Series: Earth and Environmental Science | Year: 2017

Nowadays, the shortage of water resources is a threat to us. In order to solve the problem of water resources restricted by varieties of factors, this paper establishes a water resources evaluation index model (WREI), which adopts the fuzzy comprehensive evaluation (FCE) based on analytic hierarchy process (AHP) algorithm. After considering influencing factors of water resources, we ignore secondary factors and then hierarchical approach the main factors according to the class, set up a three-layer structure. The top floor is for WREI. Using analytic hierarchy process (AHP) to determine weight first, and then use fuzzy judgment to judge target, so the comprehensive use of the two algorithms reduce the subjective influence of AHP and overcome the disadvantages of multi-level evaluation. To prove the model, we choose India as a target region. On the basis of water resources evaluation index model, we use Matlab and combine grey prediction with linear prediction to discuss the ability to provide clean water in India and the trend of India's water resources changing in the next 15 years. The model with theoretical support and practical significance will be of great help to provide reliable data support and reference for us to get plans to improve water quality. © Published under licence by IOP Publishing Ltd.

Liu Z.,Jilin University | Ma Q.,Jilin University | Wang X.,CAS Changchun Institute of Applied Chemistry | Lin Z.,Jilin University | And 3 more authors.
Biosensors and Bioelectronics | Year: 2014

In this work, a novel fluorescence "turn off-on" nanosensor for the determination of heparin and heparinase based on CuInS2 quantum dots (QDs) was established. CuInS2 QDs (modified by l-cysteine) featuring amino groups were directly prepared in aqueous solution via a hydrothermal synthesis method. The amino groups on the surface of CuInS2 QDs can interact with sulfate and carboxylate groups in heparin via electrostatic interactions and hydrogen bonding, which led the fluorescence of CuInS2 QDs to "turn-off". However, the heparin could be hydrolyzed into small fragments in the presence of heparinase, which resulted in the fluorescence of CuInS2 QDs being recovered. Therefore, the addition of heparinase to the heparin/CuInS2 QDs system activated the fluorescence of CuInS2 QDs to "turn-on" state. Thus, the determination of heparin and heparinase could be achieved by monitoring the fluorescence "turn off-on". Under the optimum conditions, there was a good linear relationship between I/I0 (I and I0 were the fluorescence intensity of CuInS2 QDs in the presence and absence of heparin, respectively) and heparin concentration in the range of 0.05-15μmolL-1 with the detection limit of 12.46nmolL-1. The linear detection for heparinase was in the range of 0.2-5μgmL-1 with the detection limit of 0.07μgmL-1. The proposed nanosensor was employed for the detection of heparin in fetal bovine serum samples with satisfactory results. © 2013 Elsevier B.V.

Kaplan J.,Jilin University
Terrorism and Political Violence | Year: 2017

This article details the long-standing struggle within the American far right between those whose mission it is to resist the perceived subversion of international communism and its neo-Soviet successors now in power in the Kremlin and those whose mission is dedicated to preserving the White Race from the twin threats of miscegenation and marginalization from the corridors of power. Using the metaphor of the 1984 low-budget spectacular Red Dawn and noting the current pattern of Russian interference in the election and contacts with the Trump campaign, it traces the struggle from the ascendancy of anti-communism in the 1950s and 1960s to the current triumph of the race warriors and conspiracy theorists who championed the candidacy of Donald Trump. “Red Dawn Is Now” concludes with the observation that, for those who most fear foreign subversion, the revelations about Russian penetration of the American election process and the Trump presidency represents a 21st-century version of the Soviet occupation that the young patriots of Red Dawn fame successfully repelled. If this is so, it suggests the possibility that Thomas Jefferson’s observation that “the tree of liberty must be refreshed from time to time with the blood of patriots & tyrants” may be prophetic and that the fifth wave of terrorism might at long last be at hand. © 2017 Taylor & Francis

Wu M.-X.,Jilin University | Yang Y.-W.,Jilin University
Advanced Materials | Year: 2017

Metal-organic frameworks (MOFs)-an emerging class of hybrid porous materials built from metal ions or clusters bridged by organic linkers-have attracted increasing attention in recent years. The superior properties of MOFs, such as well-defined pore aperture, tailorable composition and structure, tunable size, versatile functionality, high agent loading, and improved biocompatibility, make them promising candidates as drug delivery hosts. Furthermore, scientists have made remarkable achievements in the field of nanomedical applications of MOFs, owing to their facile synthesis on the nanoscale and alternative functionalization via inclusion and surface chemistry. A brief introduction to the applications of MOFs in controlled drug/cargo delivery and cancer therapy that have been reported in recent years is provided here. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Zhang P.,Jilin University
Communications in Computer and Information Science | Year: 2017

Here, after identifying the HPAI H5N1 gene data corresponding to the sites of HPAI H5N1 outbreaks in poultry and wild birds, the outbreak locations were set as the sources of human infection and a patch-based SEIR Cellular Automata (CA) epidemic model was run to simulate human responses to the HPAI H5N1 virus. HPAI H5N1 viruses from poultry and wild birds that were capable of infecting humans were identified and, through reconstruction of the phylogenetic trees with estimation of the evolutionary distances, the evolution of the HPAI H5N1 virus capable of infecting humans transmitted through poultry and wild birds was analyzed. HPAI H5N1 transmission between poultry and humans in China was modeled in different human population density scenarios from 2004–2009. The results showed that different human density distributions had little effect on the number of human cases of HPAI H5N1 and that poultry was the main source of infection. © Springer Nature Singapore Pte Ltd. 2017.

Jing X.,Jilin University
ACM International Conference Proceeding Series | Year: 2017

Phonetics is an essential part of foreign language learning. With the help of mobile communication technologies, mobile learning has developed into a new mode of learning. This paper investigates the effectiveness of mobile learning system on phonetics teaching. Fourteen-week experiment proves combining mobile learning with classroom phonetics teaching has enhanced students' phonetic awareness and effectively improved their pronunciation level. The questionnaire reveals first-year students lack a sufficient knowledge on mobile learning; teachers' instruction and supervision are needed before and during the activities. © 2017 ACM.

Lv Z.,Jilin University
International Journal of Simulation: Systems, Science and Technology | Year: 2016

In the article, it is mainly be studied on measurements and problems of the internal financial controlling in colleges and universities. It is suggested that In order to ensure the legal compliance economic activities in colleges and universities, make the financial information to be true and complete, and effectively prevent fraud and corruption, the ideology of internal controlling should be set hard in the colleges and universities, which should establish a set of internal control system and organize the implementation for suitable the needs of internal financial controlling in the colleges and universities, it will improve the level of organization and management in universities, and also make sure an efficient operation of economic activities, promote a healthy and stable development of universities. © 2016, UK Simulation Society. All rights reserved.

Cobalt oxide (Co3O4)-based materials have been extensively investigated as efficient electrocatalysts for non-enzymatic glucose biosensing. The proper tuning the structure of Co3O4-based materials could improve sensing performances for glucose detection. Herein, we have developed a combined self-assembly and calcination method to prepare nanoparticles-assembled Co3O4 nanosheets, which exhibit good sensing performances for glucose biosensing. The Co3O4 nanosheets were prepared by the following three steps: (i) the Co2+ modified graphene oxide (GO) was prepared by the self-assembly of Co2+ and GO in aqueous solution firstly, and then Co2+ modified GO film was obtained by vacuum filtration method; (ii) after calcination of Co2+ modified GO film in N2 atmosphere, Co3O4 nanoparticles modified reduced GO (RGO) was obtained; (iii) finally, nanoparticles-assembled Co3O4 nanosheets were obtained by calcination of Co3O4 modified RGO in air to remove RGO template. Most importantly, Co3O4 nanosheets exhibit good electrocatalytic activity for oxidation of glucose, leading to high-performance glucose sensor. The detection limit and linear range of Co3O4 nanosheets-based glucose sensor in the present work are 0.15 μM, and 1–50 μM, respectively. Furthermore, such sensor also shows excellent selectivity for glucose detection, compared to the commonly interfering species including dopamine, and uric acid. © 2016 Elsevier Inc.

Zhu H.,Jilin University | Jiang Z.,Jilin University
Proceedings - 2016 6th International Conference on Instrumentation and Measurement, Computer, Communication and Control, IMCCC 2016 | Year: 2016

To study UHVDC bushings insulating properties, the establishment of a condenser bushing ±800kV composite finite element model with ANSOFT analysis software selection epoxy resin and high-temperature vulcanized silicone rubber composite casing was 2D capacitive field analysis, the HVDC bushing inside the exact field intensity distribution and potential distribution. The results showed that: the interior of the casing epoxy barrier forced potential distribution, so that the electric field near the flange distribution, but also makes the flange the top two bit lines and other dramatic changes, large radial potential gradient; series of electric field strength at the flange portion and the high temperature vulcanized silicone rubber sheds maximum, a maximum of 3.44MV/m, where the problem is easy to produce flashover in UHV DC operation, provide reliable reference for the design and manufacture of bushings. © 2016 IEEE.

Liu W.,Jilin University | Shi H.,Jilin University
Proceedings - 2016 6th International Conference on Instrumentation and Measurement, Computer, Communication and Control, IMCCC 2016 | Year: 2016

this paper introduces a kind of virtual logic analyzer based on FPGA for hardware circuit and LabVIEW graphical language for the host computer software. It focuses on the integration of the hardware, and data processing by software. The results of specific tests show that the virtual instrument has the characteristics of functional modularization; friendly interface, easy maintenance, lower cost and so on. © 2016 IEEE.

Liu B.,CAS Changchun Institute of Applied Chemistry | Liu B.,Jilin University | Li S.,CAS Changchun Institute of Applied Chemistry | Wang M.,CAS Changchun Institute of Applied Chemistry | Cui D.,CAS Changchun Institute of Applied Chemistry
Angewandte Chemie - International Edition | Year: 2017

Coordination polymerization of renewable 3-methylenecyclopentene has been investigated for the first time using rare-earth metal-based precursors bearing various bulky ligands. All the prepared complexes catalyze controllable polymerization of 3-methylenecyclopentene into high molecular weight polymers, of which the NPN- and NSN-tridentate non-Cp ligated lutetium-based catalytic systems exhibited extremely high activities up to 11 520 kg/(molLu⋅h) in a dilute toluene solution (3.2 g/100 mL) at room temperature. The resultant polymers have pure 1,4-regioregularity (>99 %) and tailorable number average molecular weights (1–20×104) with narrow molecular weight distributions (polydispersity index (PDI)=1.45–1.79). DFT simulations were employed to study the polymerization mechanism and stereoregularity control. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

Wen X.,Jilin University | Jian S.,Jilin University | Wang J.,Jilin University
Fuel | Year: 2017

New prediction models based on wavelet neural networks (WNNs) have been proposed to estimate the gross calorific value (GCV) of coals. The input sets for the prediction models are involved of the proximate and ultimate analysis components of coal and the oxide analyses of ash. The coal samples, which have been employed to develop and verify the prediction models, are from United States Geological Survey (USGS) and China Huaneng Group. Some published methods have also been employed and redeveloped to make a comparison with the models proposed in this paper. The comparison reveals that the WNN models proposed here based on the proximate (ultimate) analysis components of coal, are consistently better than the published ones. The WNN models based on the oxide analyses of ash have higher accuracy in estimating the GCV of Chinese coals than US coals. Here we also analyze the possible reasons that could lead to the low estimated accuracy. © 2017

Zhang H.,Jilin University | Liu S.,Jilin University
Sensors and Actuators, B: Chemical | Year: 2017

Nanoparticles-assembled NiO nanosheets have been successfully prepared using graphene oxide (GO) film as template, where the Ni2+ ion was firstly adsorbed in GO film, followed by calcination in N2 to form NiO-based materials and calcination in air to remove carbon-based template. The morphology, structure, and electrochemical activities of these NiO nanosheets were characterized by X-ray diffraction (XRD), transmission electron microscope (TEM) and electrochemical techniques, respectively. It is found that the NiO nanosheets thus obtained could electrochemically catalyze glucose oxidation in 0.1 M NaOH, leading to fabrication of non-enzymatic glucose sensor. The glucose sensor based on NiO nanosheets exhibits detection limit of 0.18 μM, and linear range from 1 μM to 0.4 mM with the sensitivity of 1138 μA mM−2 cm−2. Furthermore, such glucose sensor also shows excellent selectivity for detection of glucose, compared to the commonly interfering species, such as ascorbic acid, dopamine, and uric acid. © 2016 Elsevier B.V.

Zhang D.,Jilin Electric Power Research Institute | Tian G.,Jilin University
Saudi Journal of Biological Sciences | Year: 2017

Stress can be either positive or negative to human beings. Under stressful conditions, the mental and physical conditions of human can be affected. There exists certain relation between stress and illness. The cortisol and other glucocorticoids bind to the same receptor, which is called glucocorticoid receptor. Some evidences indicated that cortisol molecule binding to its glucocorticoid receptor was necessary for the stress response. Up to now, the structure–function relationships between cortisol molecule and its glucocorticoid receptor have not been deliberated from the atomic-level. In order to get a detailed understanding of the structure–function relationships between the cortisol molecule and glucocorticoids receptor, we have carried out molecular dynamic (MD) simulations on glucocorticoid receptor (Apo system) and cortisol with its glucocorticoid receptor complex (HCY system). On the basis of molecular dynamic simulations, a couple of key residues were identified, which were crucial for the binding of cortisol molecule. The results of binding free energy calculations are in good agreement with the experiment data. Our research gives clear insights from atomic-level into the structural–functional aspects of cortisol molecule and its glucocorticoid receptor, and also provides valuable information for the design of drug which can treat stress related illnesses. © 2017

Kim Y.,Jilin University | Li H.,Jilin University | He Y.,Jilin University | Chen X.,Jilin University | And 2 more authors.
Nature Nanotechnology | Year: 2017

Hierarchical assemblies of biomolecular subunits can carry out versatile tasks at the cellular level with remarkable spatial and temporal precision. As an example, the collective motion and mutual cooperation between complex protein machines mediate essential functions for life, such as replication, synthesis, degradation, repair and transport. Nucleic acid molecules are far less dynamic than proteins and need to bind to specific proteins to form hierarchical structures. The simplest example of these nucleic acid-based structures is provided by a rod-shaped tobacco mosaic virus, which consists of genetic material surrounded by coat proteins. Inspired by the complexity and hierarchical assembly of viruses, a great deal of effort has been devoted to design similarly constructed artificial viruses. However, such a wrapping approach makes nucleic acid dynamics insensitive to environmental changes. This limitation generally restricts, for example, the amplification of the conformational dynamics between the right-handed B form to the left-handed Z form of double-stranded deoxyribonucleic acid (DNA). Here we report a virus-like hierarchical assembly in which the native DNA and a synthetic coat undergo repeated collective helicity switching triggered by pH change under physiological conditions. We also show that this collective helicity inversion occurs during translocation of the DNA–coat assembly into intracellular compartments. Translating DNA conformational dynamics into a higher level of hierarchical dynamics may provide an approach to create DNA-based nanomachines. © 2017 Nature Publishing Group

Sun Y.,Jilin University | Sun Y.,Indiana University – Purdue University Indianapolis | Li L.,Indiana University – Purdue University Indianapolis | Zhang Y.,Chinese Academy of Sciences
Earth and Planetary Science Letters | Year: 2017

Mg-spinel bearing lithologies, lacking abundant mafic materials, have been discovered with images acquired by the Moon Mineralogy Mapper (M3) aboard Chandrayaan-1. We conducted a systematic screening of lunar crater central peaks for the presence of Mg-spinel to address its distribution and petrogenesis. 38 Mg-spinel bearing crater central peaks were identified in this study out of 166 craters investigated. The results suggest that Mg-spinel is common in the lunar crust and appears to be extensive in the middle part of the lunar crust underneath Procellarum KREEP Terrane (PKT). Mg-spinel neither exclusively originated from deep layers (>10 km) nor necessarily coexist with the appearance of olivine or pyroxene. 15 Mg-spinel bearing central peaks originated from depth less than 10 km. Nine investigated central peaks only contain Mg-spinel and plagioclase without any detectable mafic materials. All those observations imply that the origin of Mg-spinel is possibly related to Mg-suite plutonism and assimilation between high Mg′ magma with anorthositic crust. The extensive distribution and Mg-suite related petrogenesis indicates that Mg-spinel bearing lithologies might represent a new member of Mg-suite rocks. © 2017 Elsevier B.V.

Yuan L.,Beijing Geothermal Research Institute | Yang F.,Jilin University
Jilin Daxue Xuebao (Diqiu Kexue Ban)/Journal of Jilin University (Earth Science Edition) | Year: 2017

In order to find out reservoir temperature distribution of geothermal reservoir in Beijing, aiming to complement the geothermal research of Beijing, data of 37 geothermal water samples from Beijing downtown, where has a relatively long development history of geothermal resources, including position, depth, temperature and chemistry, have been collected. Water-rock equilibrium state of the geothermal water is evaluated by the Na-K-Mg geothermometry, and Jixian Formation reservoir temperatures in the Beijing depression are calculated by using ion and SiO2 geothermometry. Vertical characteristics of reservoir temperature in the Jixian Formation are also analyzed. The results show that 35 out of 37 samples have not reached equilibrium, and the content of dissolved SiO2 is controlled by quartz in the geothermal water. Reservoir temperature of the Jianxian Formation within depth of 1000-4000 m ranges from 65.6-110.0℃, and its vertical variation is governed by difference of sedimentation. From 0 to 2000 m, no obvious trend can be observed due to the drastic change in sedimentation; below 2000 m, reservoir temperature increases with depth, and the geothermal gradient is 3.1℃/hm. © 2017, Science Press. All right reserved.

Zhao L.,Jilin University | Xi Z.,Jilin University
Materials and Design | Year: 2017

Here, nickel microspheres (Ni) were prepared by a solvothermal method, and then they were etched by Fe3 + ions in glycerol at 363 K to realize surface-nanocrystallization. By surface-nanocrystallization on Ni, the reactivity of Ni can be improved and its magnetic properties can be maintained at their usual rate, which are important for the potential application of Ni as a magnetic catalyst. In this paper, the etched nickel microspheres (NiE) as a catalyst of methanol oxidation not only show high peak of current densities but also can be easily fixed on and cleaned out of electrode owing to their excellent soft magnetic property. Moreover, an interesting phenomenon is that coalescence phenomenon on micron-scale NiE happened after irradiation of electron beam due to their high reactivity and varied structures. © 2017 Elsevier Ltd

Guo Z.,Jilin University | Li X.-Y.,China University of Petroleum - Beijing
Exploration Geophysics | Year: 2017

Azimuthal P-wave amplitude variation with offset (AVO) offers a method for the characterisation of a naturally fractured system in a reservoir. This information is important for the analysis of fluid flow during production of, for example, oil, petroleum and natural gas. This paper provides a modelling scheme by incorporating the squirt-flow model for the prediction of velocity dispersion and attenuation with azimuthal reflectivity method for the calculation of frequency-dependent seismic responses. Azimuthal AVO responses from a fractured poroelastic sandstone layer encased within shale are investigated based on the proposed method. Azimuthal reflections are a combination of the dynamic information including the contrast in anisotropic properties, anisotropic propagation and attenuation within the layer, as well as tuning and interferences. Modelling results indicate that seismic responses from the top of the sandstone layer are dominated by reflection coefficients, and show azimuthal variations at far offset which is consistent with conventional azimuthal AVO theory. Reflections from the base, however, demonstrate complex azimuthal variations due to anisotropic propagation and attenuation of transmission waves within the layer. Tuning and interferences further complicate the azimuthal AVO responses for thinner layer thickness. The AVO responses of top reflections show no azimuthal variations for lower fluid mobility, while those of base reflections show visible and stable azimuthal variations even at near and moderate offsets for different fluid mobility. Results also reveal that it would be practical to investigate wavetrains reflected from the fractured layers that are regarded as integrated units, especially for thinner layers where reflections from the top and base are indistinguishable. In addition, near-offset stacked amplitudes of the reflected wavetrains show detectable azimuthal variations, which may offer an initial look at fracture orientations before AVO analysis. © ASEG 2017.

Lin N.,Jilin University | Shi S.,Jilin University
Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering | Year: 2017

A road grade estimation model which uses the curvature to express the rate of change in the grade is proposed in this paper. The assumption that the rate of change in the road grade equals zero is widely accepted in the field of online road grade estimation. This assumption is reasonable to some extent, but it results in an inevitable time lag in the rolling-hills situation. This paper offers a road curvature estimation method which can be used to express the rate of change in the road grade. The recursive least-squares algorithm is used to the estimate the curvature, and then the Kalman filter is employed to estimate the road grade from the other vehicle states. Field tests are performed on a highway in a mountainous area. The offline road grade is used to analyse the instantaneous error and the time lag. The field test results show that the model performs well in reducing the time lag, especially in periods where the gradient changes rapidly. © Institution of Mechanical Engineers.

Zhao Z.,Jilin University | Sun H.,Jilin University
Guangdian Gongcheng/Opto-Electronic Engineering | Year: 2017

A microwave metamaterial shelter with an electromagnetic narrow window over a broad absorption spectrum is experimentally demonstrated by resorting to conventional impedance-matching theory and metamaterial resonance. This device consists of a broad absorber and an embedded electric resonator, and has the ability of permitting one to "see" surroundings but not to be readily sensed by outside detectors. The origin is verified to be a dipole oscillation excited in absorbing region which can induce selective re-emission of the captured energy towards the enclosed space. The performance of "observing without being perceived" is numerically presented. © 2017, Editorial Office of Opto-Electronic Engineering. All right reserved.

Li X.L.,Jilin University | Zhou L.M.,Jilin University
Advances in Mechanical Engineering | Year: 2017

We present an element-free Galerkin method for electromechanical coupled fracture analysis in piezoelectric materials. Singularity terms were introduced into the approximation function of the new method to describe the displacement and electric fields near the crack. The new method requires a smaller domain to describe the crack-tip singular field compared with the finite element method. Then, we computed the J-integrals of piezoelectric materials and investigated the effects of crack length on the computational precision. Numerical examples were used to highlight the accuracy of the new method compared with the analytical solutions and finite element method. © The Author(s) 2017.

OBJECTIVE: To retrospectively investigate the clinical manifestation of patients with spinal stenosis in the upper thoracic and cervical spine by posterior decompression in different ways.METHODS: From January 2010 to December 2015, 18 patients of that complicated phenomenon were studied in Department of Orthopaedic Surgery, China-Japan Union Hospital, Jilin University.Ten patients received one-stage combined decompression (group A); while the other 8 received multi-stage posterior decompression(group B). The Visual analogue scale (JOA), thoracic Cobb and range of motion(ROM) were compared.RESULT: No statistically significant inter-group difference existed in preoperative JOA score[(9.1±2.6)vs (9.1±2.2)]and postoperative JOA score[(15.4±1.2)vs(13.8±4.5)], but the mean recovery rate of nerve function of group A(79%±15%)is better than that of group B(69%±34%).CONCLUSION: All the approaches are effective for the treatment of patients with spinal stenosis in the upper thoracic and cervical spine, while one-staged combined decompression was better than double-staged operation.

Yang C.,Jilin University | Wang Y.,Jilin University | Xu H.,Jilin University
PLoS ONE | Year: 2017

This study aimed to preliminary investigate the role of activin receptor-like kinase (ALK) 5 as one of TGF-βR1 subtypes in bone turnover and osteoblastic differentiation induced by fluoride. We analyzed bone mineral density and the expression of genes related with transforming growth factor-β1(TGF-β1) signaling and bone turnover in rats treated by different concentrations of fluoride with or without SB431542 in vivo. Moreover, MTT assay, alkaline phosphatase staining, RT-PCR, immunocytochemical analysis and western blot analysis were used to detect the influence on bone marrow stem cells (BMSC) after stimulating by varying concentration of fluoride with or without SB431542 in vitro. The in vivo study showed SB431542 treatment affected bone density and gene expression of rats, which indicated TGF-β1 and ALK5 might take part in fluoride-induced bone turnover and bone formation. The in vitro study showed low concentration of fluoride improved BMSC cells viability, alkaline phosphatase activity, and osteocalcin protein expression which were inhibited by high concentration of fluoride. The gene expression of Runx2 and ALK5 in cells increased after low concentration fluoride treatment which was also inhibited by high concentration of fluoride. Fluoride treatment inhibited gene and protein expression of Samd3 (except 1 mgF- /L). Compared with fluoride treatment alone, cells differentiation was inhibited with SB431542 treatment. Moreover, the expression of Runx2, ALK5 and Smad3 were influenced by SB431542 treatment. In conclusion, this preliminary study indicated that fluoride regulated osteoblastic TGFβ1 signaling in bone turnover and cells differentiation via ALK5. © 2017 Yang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Cai B.,Jilin University | Zhou L.,Jilin University
Fuhe Cailiao Xuebao/Acta Materiae Compositae Sinica | Year: 2017

In order to improve the precision of inhomogeneous material interface crack tip fracture parameters which based on the inhomogeneous material interface fracture mechanics, Cell-Based smoothed finite element method(Cell-SFEM) and inhomogeneous material interaction integral, the Cell-Based smoothed finite element method was put forward to work out the inhomogeneous materials interface crack tip fracture parameters, and the interaction integral of inhomogeneous material based on Cell-Based smoothed finite element method was deduced. The normalized stress intensity factor in inhomogeneous material interface crack tip was solved. Compared with the reference solution, the relationship between the sizes of interaction integral region, the number of smoothing element and normalized stress intensity factor was discussed. The results of numerical example show that this method has high computational accuracy. It is not sensitive to integral area size as its features, and it can provide the basis for design and manufacture anti-failure of inhomogeneous material. © 2017, Chinese Society for Composite Materials. All right reserved.

Sundqvist B.,Jilin University
Diamond and Related Materials | Year: 2017

Fullerenes easily polymerize under high pressure by forming covalent intermolecular bonds. For C60 this reaction is easily monitored by Raman scattering, but for C70 no simple method to determine its bonding state is known. In this work C70 has been heated over a wide range of temperatures at a pressure of 1.6 GPa and the treated material has been studied by Raman spectroscopy, using 830 nm laser excitation to avoid photo-induced polymerization. By comparing the present data with earlier results for pure dimers, zig-zag chain polymers and pressure treated powders, characteristic fingerprint peaks can be found for the C70 monomer and the C140 dimer. The molecular stretching mode near 88 cm− 1 is a clear fingerprint for dimers while the strong A1′ peak near 455 cm− 1 clearly shows the presence of monomers. Several other new peaks appear in pressure-treated material and the relative intensities of many peaks change in a systematic way, but it is not clear whether these changes indicate the presence of dimers or of small oligomers in general. Simple strategies for semi-quantitative structural analysis of pressure-treated C70 material by Raman spectroscopy are briefly discussed. © 2016 Elsevier B.V.

Sun P.,Jilin University | Sun D.,Jilin University | Wang X.,Jilin University
Carbohydrate Polymers | Year: 2017

A water-soluble polysaccharide SPS2p was isolated from the whole grass of Scutellaria barbata and SPS2p contained 53.6% carbohydrates, 38.5% uronic acid and 8.2% proteins. The molecular weight of SPS2p showed only one molecular weight distribution (2.6 × 104 Da) and the monosaccharide composition of SPS2p showed the presence of arabinose, mannose, glucose and galactose at the ratio of 1.31:1.00:3.59:1.59. The results showed that SPS2p could improve the proliferation inhibition rate; SPS2p could also elevate apoptosis rate, apoptosis index and the levels of Bax and Bak, but lower levels of Bcl-2 and FN; SPS2p could up-regulate the expression of E-cadherin mRNA, and down-regulate the expressions of N-cadherin and vimentin mRNA, and the ratio of p-AKT/AKT in HT29 cells. These results indicate that SPS2p can inhibit the proliferation and EMT, and promote the apoptosis in HT29 cells, which may be related to the inhibition of SPS2p on the PI3K/AKT pathway. © 2017 Elsevier Ltd

Das S.,Jilin University | Heasman P.,Lancaster University | Ben T.,Jilin University | Qiu S.,Jilin University
Chemical Reviews | Year: 2017

Porous organic materials have garnered colossal interest with the scientific fraternity due to their excellent gas sorption performances, catalytic abilities, energy storage capacities, and other intriguing applications. This review encompasses the recent significant breakthroughs and the conventional functions and practices in the field of porous organic materials to find useful applications and imparts a comprehensive understanding of the strategic evolution of the design and synthetic approaches of porous organic materials with tunable characteristics. We present an exhaustive analysis of the design strategies with special emphasis on the topologies of crystalline and amorphous porous organic materials. In addition to elucidating the structure-function correlation and state-of-the-art applications of porous organic materials, we address the challenges and restrictions that prevent us from realizing porous organic materials with tailored structures and properties for useful applications. © 2016 American Chemical Society.

Feng J.,Jilin University | Liu Y.-F.,Jilin University | Bi Y.-G.,Jilin University | Sun H.-B.,Jilin University
Laser and Photonics Reviews | Year: 2017

The demonstration of high efficiency and color tunability has brought organic light-emitting devices (OLEDs) into the lighting and display market. High efficiency is one of the key issues for their commercial applications, for which much effort has been devoted to developing novel materials and device structures. It is well known that around 80% of the generated photons are trapped in OLED structure, so that there is still the greatest scope for significant improvements in its efficiency. This has driven the research towards the integration of micro/nano patterns into device structures that benefit from their abilities in manipulating the generation and propagation of photons. Micro/nano patterns with random or periodic morphologies have demonstrated their effect on the outcoupling of the trapped photons within the device. Moreover, the emitting properties other than the light extraction could be manipulated by introducing the micro/nano patterns. This article reviews the recent progresses in improving the light extraction and manipulating the emission properties of the OLEDs through the introduction of the micro/nano patterns by various fabrication strategies. The light manipulation of the micro/nano patterns in organic photovoltaics is briefly discussed considering its similar working principle and fabrication strategies to that of the OLEDs. (Figure presented.). © 2017 by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Wang H.,Jilin University | Zhang Y.-L.,Jilin University | Wang W.,Jilin University | Ding H.,Jilin University | Sun H.-B.,Jilin University
Laser and Photonics Reviews | Year: 2017

In the development of microfluidic chips, conventional 2D processing technologies contribute to the manufacturing of basic microchannel networks. Nevertheless, in the pursuit of versatile microfluidic chips, flexible integration of multifunctional components within a tiny chip is still challenging because a chip containing micro-channels is a non-flat substrate. Recently, on-chip laser processing (OCLP) technology has emerged as an appealing alternative to achieve chip functionalization through in situ fabrication of 3D microstructures. Here, the recent development of OCLP-enabled multifunctional microfluidic chips, including several accessible photochemical/photophysical schemes, and photosensitive materials permiting OCLP, is reviewed. To demonstrate the capability of OCLP technology, a series of typical micro-components fabricated using OCLP are introduced. The prospects and current challenges of this field are discussed. (Figure presented.). © 2017 by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Feng J.,Jilin University | Zhang Y.Q.,Jilin University | Zhang H.,Jilin University
Scientometrics | Year: 2017

We propose an improvement over the co-word analysis method based on semantic distance. This combines semantic distance measurements with concept matrices generated from ontologically based concept mapping. Our study suggests that the co-word analysis method based on semantic distance produces a preferable research situation in terms of matrix dimensions and clustering results. Despite this method’s displayed advantages, it has two limitations: first, it is highly dependent on domain ontology; second, its efficiency and accuracy during the concept mapping progress merit further study. Our method optimizes co-word matrix conditions in two aspects. First, by applying concept mapping within the labels of the co-word matrix, it combines words at the concept level to reduce matrix dimensions and create a concept matrix that contains more content. Second, it integrates the logical relationships and concept connotations among studied concepts into a co-word matrix and calculates the semantic distance between concepts based on domain ontology to create the semantic matrix. © 2017 Akadémiai Kiadó, Budapest, Hungary

Chen G.,Jilin University
SAE Technical Papers | Year: 2016

According to the vehicle's driving conditions, electronically controlled air suspension (ECAS) systems can actively adjust the height of vehicle body, so that better ride comfort and handling stability will be achieved, which can't be realized by traditional passive suspension. This paper presents a design and implementation of ECAS controller for vehicle. The controller is aimed at adjusting the static and dynamic height of the vehicle. To exactly track the height of the vehicle and satisfy the control demand of air suspension, a height sensor decoding circuit based on the inductance sensor is designed. Based on it, a new height control algorithm is adopted to achieve rapid and precise control of vehicle height. To verify the function of the designed controller and the proposed height control algorithm, an air spring loading test bench and an ECU-in-loop simulation test bench are respectively established. Copyright © 2016 SAE International.

Sun H.,Jilin University | Chen G.,Jilin University
SAE Technical Papers | Year: 2016

Distributed steering vehicle uses four steering motors to achieve four wheel independent steering. The steering angle of each wheel can be distributed respectively. The tire cornering characteristics are added to traditional steering model to study the angle allocation control algorithm. Using the constraint relation between tire slip angle, vehicle speed, yaw rate and front steering angle, and connecting with the ideal ackermann steering relationship, steering angle allocation of front wheel independent steering and four wheel independent steering is derived. Then simulated analysis is carried out to demonstrate the efficiency of the algorithm. Improvements in tire wear condition are determined by evaluating the optimization in tire lateral force, and the vehicle stability is determined by vehicle slip angle. The simulation results show that the angle allocation control algorithm has a good effect on improving tire wear condition and enhancing the stability of vehicle. Copyright © 2016 SAE International.

Cui X.,Jilin University | Chen G.,Jilin University
SAE Technical Papers | Year: 2016

The distributed driving electric vehicle, uses four in-wheel motors as distributed power sources is a typical over-actuated system. Thus, this kind of vehicle has better stability potential and fault tolerance than the conventional one. In this paper, the general structure of fault-tolerance control (FTC) system based on control allocation is analyzed. And a reconfigurable driving force allocation strategy is proposed to ensure the trajectory tracking and stability when some motors' faults occur. Both the constraints of tire force and actuators are taken into consideration. With motors' faults treated as the constraints of actuators, FTC is integrated. For validation, the proposed allocation strategy is simulated in co-simulation environment based on Carsim and Matlab/Simulink. Copyright © 2016 SAE International.

Qing Z.,Jilin University
Eurasip Journal on Embedded Systems | Year: 2017

Rock acoustic emission is often used to study the evolution of brittle materials. The cause of rock internal damage can be monitored continuously and real-timely by sensing rock acoustic wave. However, the key problem is how to split the position and analyze the acoustic emission characteristics based on the acoustic tracking experiment. First, we collected the acoustic waves of rock evolution. Then, a linear relationship is established between the acoustic emission and the propagation process of rock. And we proposed a rock sound source crowd localization algorithm. The algorithm can accurately restore the internal deformation and failure process of the rock. Finally, we designed an acoustic emission characteristic analysis method based on the acoustic source and rock sound. Test results of the ten location algorithm show that the positioning error of the proposed algorithm is less than 0.005 m, which is obviously better than the least square method. The calculation of rock strength and splitting rate is consistent with the actual measurement by using the embedded acoustic emission characteristic analysis mechanism. © 2016, The Author(s).

Zhou J.-B.,Jilin University | Wilde S.A.,Curtin University Australia | Zhao G.-C.,University of Hong Kong | Han J.,Jilin University
Earth-Science Reviews | Year: 2017

The microcontinental blocks in the CAOB include the combined NE China blocks (comprising the Erguna, Xing'an, Songliao and Jimusi-Khanka blocks) in the eastern segment of the CAOB, the Kazakhstan-Yili-Central Tianshan and Junggar blocks in the western segment of the CAOB, and the Tuva-Mongolia blocks and Beishan block in the central segment of the CAOB. The basement in these microcontinental blocks mainly consists of Archean to Paleoproterozoic crystalline rocks and/or Meso-Neoproterozoic granitoids and metamorphic complexes, indicating that most of the so-called blocks in the CAOB can be regarded as microcontinental fragments. Zircon age spectra from the eastern segment of the CAOB reveal four age peaks at 495. Ma, 780. Ma, 1825. Ma and 2600. Ma, which is similar to those recorded in the central and western segments of the CAOB. In addition, evidence of the global 'Grenvillian' tectonic event at 1000. Ma is also present in most blocks, indicating that the microcontinents in the CAOB have a common tectonic history. Furthermore, late Pan-African metamorphism at ~. 500. Ma affects all the microcontinents in the CAOB, with this granulite-facies event forming a single metamorphic belt that extends for>. 1300. km across NE China, and named the NE China Khondalite Belt in the eastern segment of the CAOB. There is also a corresponding>. 1000. km-long Sayang-Baikal orogenic belt along the southern margin of the Siberia Craton. We propose that the microcontinents of the CAOB originated as part of Rodinia along the global Grenville Orogenic Belt (1100-750. Ma). At 750-600. Ma, after the break-up of Rodinia, the various microcontinental blocks were located along the margin of Gondwana, close to the South China and Tarim cratons. At ~. 600. Ma, these blocks became detached from eastern Gondwana and, together with accreted complexes, drifted to the north (present-day co-ordinates) across the Paleo-Asian Ocean to the southern margin of the Siberia Craton, where collision took place during the late Pan-African. © 2017 Elsevier B.V.

Du L.,Jilin University
Revista de la Facultad de Ingenieria | Year: 2016

With the application of aggregation degree sensitive distance as the data similarity measure, and on the basis of the idea of multi-agent simulation, a kind of aggregation degree sensitive based multi-agent simulation clustering algorithm (Referred to as ADSMASC for short) is proposed. The algorithm has designed a kind of encoding mode on the basis of connection; through the process of decoding, the final clustering results can be obtained directly, without the necessity to determine the number of cluster classes, which has effectively overcome the reliance on the domain knowledge. According to the clustering problem, three effective simulation operators are designed to simulate the competition, cooperation and self-learning behavior between the agents, to jointly complete the simulation of the agents, and finally achieve the purpose of the clustering of data. Simulation is performed on the artificial data sets, UCI data sets and synthetic texture images respectively, and the experiment results show that, the algorithm not only can automatically determine the number of the classes of the clustering, but also can deal with the data with different structures, adapt to the requirements of different clustering, and thus have relatively strong practical value.

Li L.,Tonghua Normal University | Wu H.-Y.,Jilin University
Journal of Alloys and Compounds | Year: 2017

Novel Pr3+, Ho3+, and Er3+ single-doped CaXSrYBa1−X−YWO4 phosphors were successfully prepared via a facile hydrothermal method. The hydrothermal process was conducted in aqueous condition without the use of any organic solvent, surfactant, or catalyst. The effects of doping-host composition and RE3+ doping concentration on the emission intensity were investigated to optimize the luminescent properties of CaXSrYBa1−X−YWO4:RE3+ phosphors. Experimental results demonstrate that the morphologies of the products vary gradually and regularly with the change of the host composition, in which the anisotropic growth played a key role. Moreover, the down-conversion emissions of Pr3+, Ho3+, and Er3+ in CaXSrYBa1−X−YWO4 host were successfully realized. After optimizing the luminescent properties, Ca0.4Sr0.6WO4:0.01Pr3+, Ca0.8Sr0.2WO4:0.01Ho3+, and Ca0.6Sr0.4WO4:0.005Er3+ exhibited optimal luminescent property, with orange, yellowish-green, and green emissions, respectively. © 2017 Elsevier B.V.

Xu H.,Jilin University
Optics InfoBase Conference Papers | Year: 2016

We demonstrate that, when a femtosecond filament is formed in a combustion flame, clean fluorescence emissions from combustion intermediates can be obtained, showing the feasibility of femtosecond laser filamentation for combustion diagnostics. © OSA 2016.

Zhang Y.,Jilin Business and Technology College | Ran X.,Jilin University
Proceedings - 2016 International Conference on Robots and Intelligent System, ICRIS 2016 | Year: 2016

The data file's format of 3D model generated by GoCAD is researched, and a 3D Visualization System for GoCAD objects is developped based on VTK visualization graphics library and QT platform. It can load the pointset, curve, surface files exported from GoCAD model into true 3D render window, suplies tools for geologists to analise the geological model It is more convinient to view and analise the geological model in true 3D compared with GoCAD. © 2016 IEEE.

Zhou S.,TU Berlin | Li J.,Jilin University | Schlangen M.,TU Berlin | Schwarz H.,TU Berlin
Angewandte Chemie - International Edition | Year: 2017

The thermal gas-phase reactions of rhenium carbonyl complexes [Re(CO)x]+ (x=0-3) with methane have been explored by using FT-ICR mass spectrometry complemented by high-level quantum chemical calculation. While it had been concluded in previous studies that addition of closed-shell ligands in general decreases the reactivity of metal ions, the current work provides an exception: the previously demonstrated inertness of atomic Re+ towards methane is completely changed upon ligation with CO. Both [Re(CO)]+ and [Re(CO)2]+ bring about efficient dehydrogenation of the hydrocarbon under ambient conditions. However, addition of a third ligand to form [Re(CO)3]+ completely quenches the reactivity. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Sun W.,Jilin Institute of Chemical Technology | Pan S.,Jilin University
Multimedia Tools and Applications | Year: 2017

Graph learning is an important approach for machine learning. Kernel method is efficient for constructing similarity graph. Single kernel isn’t sufficient for complex problems. In this paper we propose a framework for multi-kernel learning. We give a brief introduction of Gaussian kernel, LLE and sparse representation. Then we analyze the advantages and disadvantages of these methods and give the reason why the combine of these methods with random walk is efficient. We compare our method with baseline methods on real-world data sets. The results show the efficiency of our method. © 2017 Springer Science+Business Media New York

Chu H.,Jilin University | Gao B.,Jilin University | Gu W.,Jilin University | Chen H.,Jilin University
IEEE Transactions on Industrial Electronics | Year: 2017

In speed control of a permanent-magnet dc torque motor, cogging torque is an undesirable disturbance and results in speed ripple. It is especially prominent at lower speeds, with the symptom of jerkiness. This paper provides a novel observer-based nonlinear triple-step controller to improve the low-speed tracking performance. Considering that cogging torque is a fast time-varying disturbance and changes harmonically, a nonlinear parameter-varying high-order system is established to model the fast-varying properties of cogging torque. Then, a reduced-order nonlinear observer is designed to estimate the cogging torque, and the robustness analysis with regard to the uncertainties is given for the proposed nonlinear observer. Thereafter, a triple-step nonlinear method is applied to derive a speed tracking controller, and then the robustness analysis against considered observation errors and lumped uncertainties is completed. Finally, the proposed control scheme is verified through experimental tests, and the results show that tracking errors are substantially reduced at low speeds. © 2017 IEEE.

Objective: To express recombinant Staphylococcus aureus enteroxtoxin B (rSEB) and heat shock protein 65 (HSP65) fusion protein in prokaryotic cells and investigate its humoral immune effect in mice. Methods Recombinant plasmid pET-rSEB-HSP65 was constructed by fusion of a SEB gene in which TCR VB binding region was modified with HSP65 gene by molecular biological technique, and transformed to E. coli BL21 (DE3) for expression under induction of IPTG. The expressed product was purified by affinity chromatography, with which mice were injected s.c. on days 0, 14 and 28. Serum samples were collected on days 14, 28 and 42, and determined for anti-SEB IgG by indirect ELISA. Results: Restriction analysis and PCR proved that recombinant plasmid pET-28a-rSEB-HSP65 was constructed correcdy. The expressed rSEB-HSP65, with a relative molecular mass of about 85 000, mainly existed in a form of inclusion body, contained about 40. 81% of total somatic protein, and reached a purity of about 90% after purification. High antibody titers were induced in mice in various groups. Most of the GMTs of mice on days 14, 28 and 42 after immunization with aluminum adjuvant-containing vaccine were significantly higher than those with aluminum adjuvant-free vaccine at the same dosages (each P < 0. 05). However, the GMTs of mice 42 d after immunization with aluminum adjuvant-containing vaccine at a low dosage showed no significant difference with those with aluminum adjuvant-free vaccine at the same dosage (P> 0. 01). Conclusion: Recombinant vaccine rSEB-HSP65 was successfully expressed in E. coli BL21(DE3), which induced high antibody level in mice.

Xu Q.,Jilin University | Li Y.,University of Missouri | Zhang L.,Jilin University | Zheng W.,Jilin University | And 3 more authors.
Chemistry of Materials | Year: 2017

We theoretically investigate Sn(II) phosphates as optoelectronic materials using first-principles calculations. We focus on known prototype materials SnnP2O5+n (n = 2, 3, 4, 5) and a previously unreported compound, SnP2O6 (n = 1), which we find using global optimization structure prediction. The electronic structure calculations indicate that these compounds all have large band gaps above 3.2 eV, meaning they are transparent with visible light. Several of these compounds show relatively low hole effective masses (∼2-3 m0), comparable the electron masses. This suggests potential bipolar conductivity depending on doping. The dispersive valence band-edges, underlying the low hole masses, originate from the antibonding hybridization between the Sn 5s orbitals and the phosphate groups. Analysis of structure-property relationships for the metastable structures generated during the structure search shows considerable variation in combinations of band gap and carrier effective masses, implying chemical tunability of these properties. The unusual combinations of relatively high band gap, low carrier masses, and high chemical stability suggest possible optoelectronic applications of these Sn(II) phosphates, including p-type transparent conductors. Related to this, calculations for doped material indicate low visible light absorption, combined with high plasma frequencies. © 2016 American Chemical Society.

Yang X.,Jilin University | Zhao L.,Jilin University | Lian J.,Jilin University
Journal of Power Sources | Year: 2017

One-dimensional (1D) hierarchical structures composed of nickel sulfides/MoS2 (NMS) supported on carbon nanotube (CNT) are fabricated through a one-step facile glucose-assisted hydrothermal method (NMS/CNT). The curled and tangled 1D structure is intertwined with each other and constructs three-dimensional (3D) porous networks, providing easy access of electrolyte. Meanwhile, the formation of metallic 1T-2H hybridized MoS2 and the synergistic effect between the MoS2 layers and nickel sulfides (NS) nanoparticles promotes the ions diffusion on the surface of the electrode, and the void space formed between NMS sheets can endure volume change in redox process for more stable structures. Therefore, the assembled NMS/CNT//activated carbon (AC) asymmetric supercapacitor manifests favorable specific capacitance of 108 F g−1 at 0.5 A g−1, along with a high energy density of 40 Wh kg−1 and good cycling stability of almost 100% capacity maintained after 10,000 cycles, implying it's the promising candidate for energy storage. © 2017 Elsevier B.V.

Ma Y.,Jilin University | Liu J.,Jilin University | Li H.,Jilin University
Biosensors and Bioelectronics | Year: 2017

In this study, we designed and fabricated an electrochemical impedance aptasensor based on Au nanoparticles (Au-NPs) coated boron-doped diamond (BDD) modified with aptamers, and 6-mercapto-1-hexanol (MCH) for the detection of bisphenol A (BPA). The constructed BPA aptasensor exhibits good linearity from 1.0×10–14 to 1.0×10−9 mol L−1. The detection limitation of 7.2×10–15 mol L−1 was achieved, which can be attributed to the synergistic effect of combining BDD with Au-NPs, aptamers, and MCH. The examine results of BPA traces in Tris-HCl buffer and in milk, UV spectra of aptamer/BPA and interference test revealed that the novel aptasensors are of high sensitivity, specificity, stability and repeatability, which could be promising in practical applications. © 2017 Elsevier B.V.

du R.,Changchun University of Technology | Xu F.,Jilin University
Journal of Dynamical and Control Systems | Year: 2017

This paper deals with the null controllability of the system governed by coupled degenerate equations with the first order terms. The null controllability of the system with two controls is proved firstly, then the system with one control is shown to be null controllable by constructing the control function. To investigate the null controllability, we establish the Carleman estimate and the observability inequality for the adjoin system by using the Carleman estimate for the single degenerate equation. © 2017 Springer Science+Business Media New York

Liu Z.,Jilin University | Su X.,Jilin University
Biosensors and Bioelectronics | Year: 2017

In this work, a novel fluorescent DNA sensor for ultrasensitive detection of Helicobacter pylori (H. pylori) DNA was developed. This strategy took advantage of DNA hybridization between single-stranded DNA (ssDNA, which had been designed as an aptamer specific for H. pylori DNA) and the complementary target H. pylori DNA, and the feature that ssDNA bound to graphene oxide (GO) with significantly higher affinity than double-stranded DNA (dsDNA). ssDNA were firstly covalent conjugated with CuInS2 quantum dots (QDs) by reaction between the carboxy group of QDs and amino group modified ssDNA, forming ssDNA-QDs genosensor. In the absence of the complementary target H. pylori DNA, GO could adsorb ssDNA-QDs DNA sensor and efficiently quench the fluorescence of ssDNA-QDs. While the complementary target H. pylori DNA was introduced, the ssDNA-QDs preferentially bound with the H. pylori DNA. The formation of dsDNA would alter the conformation of ssDNA and disturb the interaction between ssDNA and GO. Thus, the dsDNA-QDs/GO system exhibited a stronger fluorescence emission than that of the ssDNA-QDs/GO system. Under the optimized conditions, a linear correlation was established between the fluorescence intensity ratio I/I0 and the concentration of H. pylori DNA in the range of 1.25–875 pmol L−1 with a detection limit of 0.46 pmol L−1. The proposed method was applied to the determination of H. pylori DNA sequence in milk samples with satisfactory results. © 2016 Elsevier B.V.

Ma R.,Jilin University | Zhao H.,Macau University of Science and Technology
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2017

Stock market is definitely one of the common choices for investment throughout the world. Stock market index is well known as the composite of several representative stocks and reflects the trends of future stock market. Predicting the change of stock market index becomes crucial for individual investor, companies and stock holders. Recent research from behavioral finance implies that emotions of investors from social media can also influence stock market index in addition to the commonly used financial factors. Taking the advantages from the development of modern network and the age of big data, we are able to obtain information from different sources. More specifically, accessing user data from social media is no longer a challenge. Thus we apply data mining methods and propose to use the key words of emotions of market participates obtained from social media through text mining to predict the change of stock market index. Compared with traditional methods, we are able to utilize full information from the social network. We apply the propose approach in a dataset collected from Xueqiu forum, and the results show that linear discriminant analysis could give relatively good predictions of stock market index. © Springer International Publishing AG 2017.

Wu H.,Jilin University
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2017

The log generated by the software system becomes bigger and bigger, which are including many important and valuable information, so it will have a very high commercial value in the future. Because the log information is complex, it is difficult to mine numerous relative data and receive valuable one by means of the traditional technology. The capability of the big data process on Hadoop is much faster than that of traditional modus. This research is primary to analyze the weather log apace, taking advantage of the parallel process on Hadoop. It forms the B/S structure system and utilizes the High charts plug-in to generate charts to display to the user, in the light of that people may forecast the temperature change and make a decision. By applying a test it shows a perfect application, a good graphical interface and an elevated operability and interactivity, so it is more convenient and much faster, and much simpler to show the results of the analysis directly. © Springer International Publishing AG 2017.

Fu X.,Jilin University
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2017

Many learning algorithms can suffer from a performance bias for classification with imbalanced data. This paper proposes the pre-training the deep structure neural network by restricted Boltzmann machine (RBM) learning algorithm, which is pre-sampled with standard SMOTE methods for imbalanced data classification. Firstly, a new training data set can be generated by a pre-sampling method from original examples; secondly the deep neural network structure is trained on the sampled data and all unlabelled data sets by RBM greedy algorithm, which is called “coarse tuning”. Then the neural networks are fined tuned by BP algorithm. The effectiveness of the RBM pre-training neural network (RBMPT) classifier is demonstrated on a number of benchmark data sets. Compared with only BP classifier, pre-sampling BP classifier and RBMPT classifier, it has shown that pre-training procedure can learn more representations of data better with unlabelled data and has better classification performance for classification with imbalanced data sets. © Springer International Publishing AG 2017.

Jiang Y.,Jilin University | Ma W.,Jilin University
Medical Science Monitor | Year: 2017

Background: To develop new strategies for identifying atopic dermatitis patients, a better understanding of the signs for chronic inflammatory status is needed. This study was designed to investigate whether neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are related to the severity of atopic dermatitis (AD) assessed by the Scoring Atopic Dermatitis (SCORAD) index. Material/Methods: A retrospective study involving 80 AD patients and 45 healthy control subjects was performed. NLR, PLR, and the number of peripheral blood eosinophils were compared between AD patients and healthy controls, and correlations between these indexes and clinical characteristics were analyzed. Results: NLR, PLR, and eosinophils in AD patients were all significantly higher than in healthy individuals. Among AD patients, NLR (p<0.001) and PLR (p<0.001), as contrasted with eosinophils (p=0.146), were correlated positively with SCORAD index. Additionally, an NLR level of 1.75 was determined as the predictive cut-off value of severe AD (SCORAD ≥51) (sensitivity 94.7%, specificity 58.6%, the area under the receiver-operating characteristic curve (AUROC) 0.778, p=0.001). For eosinophils, the sensitivity and specificity were 78.9% and 62.1%, respectively, and the AUROC was only 0.685 (p=0.032) in predicting high SCORAD. Conclusions: NLR and PLR reflect inflammatory response and disease severity in AD patients. © Med Sci Monit.

Zhang W.,Jilin University
Pancreas | Year: 2017

OBJECTIVE: The aim of this study was to establish a suitable rabbit model and select the optimal protocol for laparotomy cryoablation of pancreatic carcinoma. METHODS: VX2 tumor tissues were inoculated into rabbit pancreases to build the pancreatic carcinoma model; then, the tumor-bearing rabbits were randomly divided into 4 groups: control, treatment A (the cryoablated-iceball diameter was bigger than the tumor), treatment B (iceball was as big as the tumor), and treatment C (iceball was smaller than the tumor). Related laboratory tests were conducted, and survival time was recorded. RESULTS: The VX2 pancreatic carcinoma model was successfully established, and serum neuron-specific enolase levels increased continuously after inoculation. Compared with controls, rabbits in treatments A and C groups had no significant survival benefit (P > 0.05), but treatment B significantly prolonged the survival time (P < 0.01). CONCLUSIONS: VX2 pancreatic cancer model was successfully established with neuron-specific enolase as biomarker. Treatment B may be the optimal protocol for pancreatic carcinoma and a new treatment option for patients with unresectable pancreatic cancer. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

Gong M.,Jilin University | Qin Y.,Jilin University
Proceedings - 2016 8th International Conference on Intelligent Human-Machine Systems and Cybernetics, IHMSC 2016 | Year: 2016

According to the force feedback effect is not sufficient and the impact on the operator's problems, the variable gain position constraint space bilateral servo force feedback control strategy is put forward in this paper. The mathematical model of the electro-hydraulic servo control system of the master-slave hand is established, then the PD controller is designed by using the parameter space graphic method to improve the dynamic response characteristics of the electro hydraulic servo system. Finally, through the simulation experiments under the conditions of no load, spring load and rigid load, the effectiveness of the proposed control strategy is verified. © 2016 IEEE.

Chen Y.,Jilin University | Wu W.,Changchun Institute of Urban Planning and Design
Ore Geology Reviews | Year: 2017

In this research, we conduct a case study of mapping polymetallic prospectivity using an extreme learning machine (ELM) regression. A Quad-Core CPU 1.8 GHz laptop computer served as hardware platform. Almeida's Python program was used to construct the ELM regression model to map polymetallic prospectivity of the Lalingzaohuo district in Qinghai Province in China. Based on geologic, metallogenic, and statistical analyses of the study area, one target and eight predictor map patterns and two training sets were then used to train the ELM regression and logistic regression models. ELM regression modeling using the two training sets spends 61.4 s and 65.9 s; whereas the logistic regression modeling using the two training sets spends 1704.0 s and 1628.0 s. The four trained regression models were used to map polymetallic prospectivity. Based on the polymetallic prospectivity predicted by each model, the receiver operating characteristic (ROC) curve was plotted and the area under the curve (AUC) was estimated. The ROC curves show that the two ELM-regression-based models somewhat dominate the two logistic-regression-based models over the ROC performance space; and the AUC values indicate that the overall performances of the two ELM-regression-based models are somewhat better than those of the two logistic-regression-based models. Hence, the ELM-regression-based models slightly outperform the logistic-regression-based models in mapping polymetallic prospectivity. Polymetallic targets were optimally delineated by using the Youden index to maximize spatial association between the delineated polymetallic targets and the discovered polymetallic deposits. The polymetallic targets predicted by the two ELM-regression-based models occupy lower percentage of the study area (2.66–2.68%) compared to those predicted by the two logistic-regression-based models (4.96%) but contain the same percentage of the discovered polymetallic deposits (82%). Therefore, the ELM regression is a useful fast-learning data-driven model that slightly outperforms the widely used logistic regression model in mapping mineral prospectivity. The case study reveals that the magmatic complexes, which intruded into the Baishahe Formation of the Paleoproterozoic Jinshuikou Group or the Carboniferous Dagangou and Shiguaizi Formations, and which were controlled by northwest-western/east-western trending deep faults, are critical for polymetallic mineralization and need to be paid much attention to in future mineral exploration in the study area. © 2016 Elsevier B.V.

Li Q.,Jilin University | Zhao Y.,Jilin University
Proceedings of SPIE - The International Society for Optical Engineering | Year: 2016

The existence of vertical parallax is the main factor of affecting the viewing comfort of stereo video. Visual fatigue is gaining widespread attention with the booming development of 3D stereoscopic video technology. In order to reduce the vertical parallax without affecting the horizontal parallax, a self-Adaptive image scaling algorithm is proposed, which can use the edge characteristics efficiently. In the meantime, the nonlinear Levenberg-Marquardt (L-M) algorithm is introduced in this paper to improve the accuracy of the transformation matrix. Firstly, the self-Adaptive scaling algorithm is used for the original image interpolation. When the pixel point of original image is in the edge areas, the interpretation is implemented adaptively along the edge direction obtained by Sobel operator. Secondly the SIFT algorithm, which is invariant to scaling, rotation and affine transformation, is used to detect the feature matching points from the binocular images. Then according to the coordinate position of matching points, the transformation matrix, which can reduce the vertical parallax, is calculated using Levenberg-Marquardt algorithm. Finally, the transformation matrix is applied to target image to calculate the new coordinate position of each pixel from the view image. The experimental results show that: comparing with the method which reduces the vertical parallax using linear algorithm to calculate two-dimensional projective transformation, the proposed method improves the vertical parallax reduction obviously. At the same time, in terms of the impact on horizontal parallax, the proposed method has more similar horizontal parallax to that of the original image after vertical parallax reduction. Therefore, the proposed method can optimize the vertical parallax reduction. © 2016 SPIE.

Wang J.,Jilin University
Proceedings of SPIE - The International Society for Optical Engineering | Year: 2017

In this paper, we propose a new inclusion measure between fuzzy sets. Firstly, we select an axiomatic definition for the inclusion measure. Then, we present a new computation formula based on the selected axiomatic definition, and demonstrate its two properties. Finally, we give examples to validate its performance. The results show that the new inclusion measure is rational for fuzzy sets. © 2017 SPIE.

Na Y.,Jilin University | Yang Y.,Changchun Institute of Technology
Proceedings - 9th International Conference on Measuring Technology and Mechatronics Automation, ICMTMA 2017 | Year: 2017

For gold exploration and sustainable exploitation, it has great significance for the genesis of gold deposit mineralization enrichment regularity. Jiaodong area is one of the most important gold producing areas in China, whose reserves account for about 1 /3 of proven rock gold reserves in China. In this paper, we take northwest of Jiaodong gold concentration area, the eastern side of Yishu fault zone and Xincheng fault structure zone as the main research object to obtain the zircon U-Pb age of the Linglong granite and guojialing granodiorite, which is 158.53 + 0.79Ma and 135.56 + 0.53Ma. On the basis of the general analyzing research of the spatial variation law of ore controlling structure, the dynamic characteristics of ore controlling faults, the spatial location mechanism of industrial ore-bodies and other mineralization enrichment regularity, the analysis shows that there is another mineralization enrichment section in the deep part of the mining area. Namely, the dip angle of the fracture where occurrence tend to be gently is a favorable region for mineralization, that is the second mineralization enrichment segment, whcih provides theoretical basis for the next step of prospecting work. © 2017 IEEE.

OBJECTIVE:: Gallic acid, a natural chemical found in plants, has been reported to show antioxidant, anticancer, and anti-inflammatory effects. We investigated the efficacy of a short-term or long-term treatment with gallic acid in N-nitro-L-arginine methyl ester (L-NAME)-induced hypertensive mice and the underlying regulatory mechanism. METHODS:: Hypertension was sufficiently induced after 2 weeks of L-NAME administration. Cardiac remodeling was assessed by echocardiography. Hypertrophic markers, transcription factors, and fibrosis-related gene expression were evaluated by quantitative real-time polymerase chain reaction and western blotting. RESULTS:: Gallic acid effectively lowered SBP, regardless of the administration route (intraperitoneal or oral). L-NAME increased the left ventricular (LV) thickness without an increase in the total heart weight. Weekly echocardiography demonstrated that gallic acid significantly reduced LV posterior wall and septum thickness in chronic L-NAME mice from 3 to 7 weeks. The administration of gallic acid to mice showed a dual preventive and therapeutic effect on the L-NAME-induced LV remodeling. The effect was associated with the suppression of the gene expression of hypertrophy markers and the GATA-binding factor 6 (GATA6) transcription factor. Short-term or long-term treatment with gallic acid attenuated cardiac fibrosis and reduced the expression of histone deacetylase 1 and 2 in H9c2 cells and in rat primary cardiac fibroblasts, as well as in vivo. Small interfering RNA knockdown confirmed the association of these enzymes with L-NAME-induced cardiac remodeling and fibrosis. CONCLUSION:: These results suggested that gallic acid may be a potential therapeutic agent for the treatment of cardiovascular diseases with hypertension and cardiac fibrosis. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.

Lu X.B.,Jilin University
Genetics and Molecular Research | Year: 2017

With the expanding demand for genetically modified (GM) rice, its safety evaluation is of great significance. Therefore, this study was carried out to assess the acute cytotoxicity of the whole protein extract from GM rice Bar68-1 in Mus musculus lymphocytes in vitro. Cell viability was determined by Cell Counting Kit-8 (CCK-8) and Neutral Red Uptake (NRU) tests. CCK-8 tests was carried out according to the manufacturer’s instructions. Cell dehydrogenase (catalytic redox enzymes) activity was spectrophotometrically determined at 450 nm. The tests result were recorded immediately. NRU tests were completed under yellow light in a dark room according to an improved protocol. Lysosomal uptake of neutral red was spectrophotometrically determined at 540 nm and the results were recorded immediately. The results showed that the survival rate of M. musculus lymphocytes in the positive control group was significantly less than in the blank control group (P < 0.05). Moreover, an exposure- time-effect relationship was observed in the positive control group with CCK-8 and NRU tests. There was no significant difference in survival rate between GM rice Bar68-1group and non-GM rice D68 group (P > 0.05). The GM rice Bar68-1 group also did not show a higher survival rate than non-GM rice D68 group (P > 0.05). These results suggested that the whole protein extract from Bar68-1 and D68 were equivalent in their cytotoxicity, and GM rice Bar68-1 had no acute cytotoxic effect on M. musculus lymphocytes in vitro. © 2017 The Authors.

Jiang X.,Jilin University | Zhang L.,Jilin University
International Journal of Heat and Technology | Year: 2017

This paper analyzes the advantages and defects of the k-ω SST turbulence model when adopted for simulation calculation under working conditions of rotational motion and curved walls. On the basis of this model and in consideration of the rotational motion and the curvature effect, the author introduces the correction equation proposed by Spalart on the basis of the steady-state rotation effect, and Hellsten's Richardson number correction model, recalculates the specific dissipation rate in the near-wall area by the EWT, and corrects the turbulent kinetic energy generation term in the turbulence model. The author applies the original and the improved turbulence models in the calculation of the lift and efficiency of the centrifugal pump and finds that the calculation results of the improved model are closer to the experimental results at a rotating speed of 2,500n/min or above. The calculation results are optimal under the working condition of a rotating speed of 3,370n/min and a flow of 180L/min. The calculated result of pump lift is 21.04m, with a calculation error of 0.67%, meaning that the calculation accuracy is improved by 0.3%; the calculated result of efficiency is 26.2%, with a calculation error of 0.76%, meaning that the accuracy is improved by 0.7%. After analyzing the inner flow field, the author finds that in the turbulence intensity nephogram calculated by the improved model, the turbulence intensity in the outlet area is low, the forward trend along the curved wall is weak and the veolocity is significantly reduced. From the turbulence kinetic energy nephogram, it can be seen that the calculation results of the improved model are low at the outlet and the central area, and that the turbulence development is weak. By comparing the calculation results and experimental results of the original model and the improved one, it can be proved that the improved turbulence model has higher calculation accuracy.

Zhou H.,Jilin University | Fu J.,Jilin University | Cai Z.-W.,Hong Kong Baptist University
Journal of Chinese Mass Spectrometry Society | Year: 2017

Aristolochic acids (AAs), derived from aristolochia plant species, are a mixture of structural-related compounds. Aristolochic acid I and aristolochic acid II are reported to be the major components that are associated with kidney damage toxicity and carcinogenic mutagenicity toxicity. Since the toxicity mechanism of action of Aristolochic acids are still unclear, it is necessary to develop a sensitive analytical method to facilitate these studies. In this work, a rapid and sensitive method based on high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was applied for the determination of aristolochic acid I, aristolochic acid II and their major metabolites in samples from in vitro metabolism studies. Aristolochic acid I and aristolochic acid II were incubated with rat liver microsome S9 fractions under aerobic and anaerobic conditions. The incubation samples were analyzed by HPLC-MS/MS. The obtained results showed that the in vitro metabolic pathways of aristolochic acid I and aristolochic acid II are different. The metabolites of aristolochic acid I was detected and characterized as aristolochic acid Ia under aerobic condition and aristololactam I under anaerobic condition, respectively; however, in the case of aristolochic acid II, the only metabolite of aristolochic acid II was identified as aristololactam II under the anaerobic condition. Besides, the fragmentation behaviors of aristolochic acid I, aristolochic acid II and their metabolites in rat liver microsomes S9 fractions were characterized and summarized. The results indicated that the production of aristololactams is the main cause of the toxicity of aristolochic acid I and aristolochic acid II in the metabolism of rat liver microsome S9. This study have a certain significance for better understanding of the toxicity mechanism of action of aristolochic acid I and aristolochic acid II, as well as for toxicity monitoring of aristolochia plants. © 2017, Editorial Board of Journal of Chinese Mass Spectrometry Society. All right reserved.

INTERVENTIONS: 2 patients received chemotherapy ,but others rejected treatment.OUTCOMES: Most patients died within 1 year after the onset of skin lesions.LESSONS: These findings suggest that skin infiltration of AML may precede any systemic evidence, and typical cutaneous lesions in elderly individuals may be indicative for AML.RATIONALE: Cutaneous presentation preceding acute myeloid leukemia (AML) is rare, and the prognosis is poor.PATIENT CONCERNS: We report 4 cases of AML cutis, where skin infiltration precedes any blood or bone marrow evidence of leukemia. We also reviewed 13 cases reported in English and Chinese literature. The 4 cases all presented typical cutaneous lesions without any systemic evidence of leukemia. Histopathological examination found that dense monomorphous cell infiltration involved the dermis. Some cells surrounded blood vessels and skin appendages in a concentric manner or showed single-row arrangement in the collagen fiber bundles. Uninvolved papillary dermis was found to separate normal epidermis from dermal infiltration. Minor cells had a large kidney-shaped or oval nucleus with nucleoli and slightly eosinophilic cytoplasm. Immunohistochemical analysis was positive for CD4, CD56, while CD123 was negative in all cases.AML-M5.

Xian W.,Jilin University | Wang D.F.,Jilin University | Wang D.F.,Japan National Institute of Advanced Industrial Science and Technology
Applied Physics Letters | Year: 2017

A position and orientation correction scheme for current sensing based on magnetic piezoelectric cantilevers is proposed in this letter, offering an insight for the improvement of measurement accuracy. In this scheme, an array of magnetic piezoelectric cantilevers, converting mechanical vibration generated by current induced magnetic force applied on magnets at the ends of cantilevers into output voltages, is utilized. A system of nonlinear equations is established in terms of amplitude of objective current, position, and orientation errors. They are derived by solving the system of equations treated as variables, instead of parameters. As a result, the measurement error caused by position and orientation errors decreased substantially. Experiments of passive current sensing for two-wire appliances prove the validity of the proposed position and orientation correction scheme. The application of the proposed scheme can be further extended to sensors based on the magnetic field sensing mechanism, for achieving higher measurement accuracy. © 2017 Author(s).

Zhang H.,Jilin University | Li W.,Jilin University
Proceedings - 2016 9th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics, CISP-BMEI 2016 | Year: 2016

Sensor fault diagnosis is one of the important parts of a vehicle control system. Normally we sort sensor faults as incipient-faults and abrupt-faults [5]. In this paper, we focus on the sensor abrupt-faults of Hybrid electric vehicles (HEV) control system. A novel method for diagnosing sensor abrupt-faults is proposed based on the wavelet packet neural network (WPNN). The simulating test is conducted in Matlab/Simulink and MotoTron rapid prototyping platform. The results after simulating show that this approach is feasible and effective in detecting sensor abrupt-faults. © 2016 IEEE.

Zhao X.,Zhejiang Normal University | Ouyang D.,Jilin University
2016 IEEE International Conference on Information and Automation, IEEE ICIA 2016 | Year: 2016

Deriving all minimal hitting-sets (MHSes), as candidate diagnoses, is an active topic in model-based diagnosis. Based on the "Divide and Conquer" principle, an algorithm for computing all MHSes by recursive merging is proposed. First, each given (large) family of conflict sets is divided into two smaller sub-families, every one of which is used for computing its own MHSes, respectively. Then, the cross-product of the two corresponding sub-families of MHSes is generated. Finally, the family of MHSes for the whole conflict sets is obtained, only with the additional final step: minimizing the product. Detailed theoretical analysis of time complexity is given in different cases. Experimental results show that our approach has better efficiency than other approaches in many cases. © 2016 IEEE.

Meng X.,Jilin University
2016 IEEE International Conference on Information and Automation, IEEE ICIA 2016 | Year: 2016

In this paper, a novel decentralized key-policy attribute-based signcryption scheme is proposed, where the decentralized authority A can generate an attribute-based key pair for the sensitive data owner independently. In the proposed scheme, the sensitive data owner can share sensitive data through specifying an attribute-based access control structure so that any users whose attributes satisfy it can be allowed to access the sensitive data without knowing the sensitive data owner's unique identity information. Therefore, it is clear that the decentralized authority can reduce the communication cost and the collab ENGLorative cost. Additionally, the decentralized key-policy attribute-based signcryption scheme is efficient in terms of both the security communication and identification authentication, and can realize security sensitive data sharing for valid users in cloud computing environments. © 2016 IEEE.

Yang W.,Jilin University | Zhao X.,Jilin University
2016 IEEE Global Communications Conference, GLOBECOM 2016 - Proceedings | Year: 2016

In this paper, we study the robust relay selection and power allocation problems for orthogonal frequency division multiplexing (OFDM) based cooperative cognitive radio networks (CRNs) with channel uncertainties. The objective is to maximize the capacity of the cooperative CRN, which is subject to the interference threshold constraints of primary users (PUs) and the total transmit power limitation of secondary user (SU) and relays. We describe all possible channel uncertainties with ellipsoid set and interval set. The robust relay selection and power allocation problems are formulated as semi-infinite programming (SIP) problems, respectively. We convert the SIP problems into their equivalent convex optimization problems with the worst-case approach, which can be solved by the Lagrange dual decomposition method. Simulation results show that the proposed robust relay selection and power allocation algorithm can strictly guarantee the quality of service of PUs under channel uncertainties. © 2016 IEEE.

Dong A.,Inner Mongolia University | Wang Y.-J.,University of British Columbia | Gao Y.,Inner Mongolia University | Gao T.,Inner Mongolia University | Gao G.,Jilin University
Chemical Reviews | Year: 2017

Microbial contamination arising from pathogens poses serious threats to human health and in recent decades has presented an unprecedented challenge to antibacterial research. Of the various antibacterial agents that effectively kill pathogens, halogen-based antibacterial compounds have been successful in eliminating harmful pathogen-associated diseases and are becoming the most popular disinfectants. As a significant subcategory of halogen antibacterial agents, N-halamines have drawn increasing research interest into their chemistry and practical applications. N-Halamines have many advantages over other antibacterial agents, including effectiveness against a broad spectrum of microorganisms, long-term physicochemical stability, high structural durability, and the regenerability of their functional groups, with corresponding renewal of their antibacterial properties. This review examines recent progress and research trends in both theoretical and experimental studies of N-halamines, with the aim of providing a systematic and comprehensive survey and assessment of the significant advances in our understanding of antibacterial N-halamines. This review serves as a practical guide to developing N-halamines through both broad and in-depth basic research and offers suggestions for their potential future applications. © 2017 American Chemical Society.

News Article | April 25, 2017

Researchers have developed a process to make light-emitting diodes by spraying a substrate with quantum dots (ACS Photonics 2017, DOI: 10.1021/acsphotonics.7b00216). The quantum-dot LEDs (QLEDs) are 100 times as bright and efficient as similar devices, the researchers say. The process could someday be used to mass-produce inexpensive, vibrant, and flexible displays. Quantum dots are semiconductor nanocrystals that emit a single wavelength when stimulated by electricity or light. This pure color can be tuned by changing the size or composition of the nanocrystals. In some electronic displays on the market today, quantum dots convert blue light from a conventional LED into red and green light, needed for a full-color display. But engineers want to make true QLED displays in which quantum dots at each pixel are electrically triggered to emit each of those three colors. Such displays should be rich, bright, and energy efficient. The question is how to make QLEDs on large areas. A QLED contains quantum dots sandwiched between a layer that transports negatively charged electrons and one that transports positively charged holes. To make these various layers, researchers coat glass or plastic substrates with layers of charge-ferrying organic polymers and quantum dots using vacuum deposition or spin-coating. But the vacuum method is expensive and complicated, and it is difficult to make high-quality films over large areas with spin-coating. “These are not suitable for industry-scale production,” says Wenfa Xie, a professor of electronic science & engineering at Jilin University. Spraying is a much simpler and cheaper way to coat large areas, including flexible plastic sheets. So Xie, Hanzhuang Zhang, and their colleagues created prototype 5-mm2 QLEDs by spraying a series of three nanoparticle solutions onto a glass substrate, depositing one layer at a time. For this, they used an ultrasonic spray machine, which vibrates to break down a liquid into tiny droplets and releases them from a nozzle as an ultrafine spray. The quantum dots were made of cadmium selenide-cadmium sulfide cores and zinc sulfide shells, which glow green when excited with electricity. Xie and his colleagues chose inorganic metal oxides as charge-transport layers instead of organic polymers because organic materials don’t last long under air and humidity and require expensive encapsulation. The team used zinc oxide nanoparticles for the electron-transporting layer and nickel oxide nanoparticles for the hole-transporting layer. To boost efficiency, Xie and his colleagues sprayed a layer of aluminum oxide between the nickel oxide and quantum dot layers, which helps to quash charge-trapping defect sites in the nickel oxide. The team produced green QLEDs with an efficiency of 20.5 candelas per ampere and a brightness of more than 20,000 cd/m2. These numbers are two orders of magnitude greater than previously reported QLEDs made with all inorganic materials, Xie says. The process could easily be used to make QLEDs of other colors. But the devices still need to catch up in brightness and lifetime with organic polymer-based QLEDs, which can be twice as efficient and last 10 times as long. Xie says that his team is now trying to improve both traits by engineering better quantum-dot and hole-transport layers. Paul Holloway, a materials science & engineering professor at the University of Florida, says the spray process is unique for making QLEDs. Manufacturers would still need to figure out how to pattern the QLEDs to make pixels for displays, he adds, but there are many ways to do that.

Zheng K.,Jilin University | Song W.,Jilin University | He G.,Jilin University | Yuan Z.,University of Macau | Qin W.,Jilin University
Optics Express | Year: 2015

Under 980 nm excitation, the temperature dependence of fivephoton UV (256 and 276 nm) upconversion luminescence in Yb3+-Er3+ codoped β4-NaLuF4 nanocrystals was studied from 303 K to 523 K. The 4D7/2 and 4G9/2 levels of Er3+ are confirmed to be thermally coupled levels. They are the highest energy states for optical thermometry known so far. By using fluorescence intensity ratio technique, optical temperature sensing characteristics based on the 4D7/2/4G9/24I15/2 transitions of Er3+ were reported here for the first time. The obtained sensitivity of this UV-based sensor is higher than that of green-based optical thermometer in low temperature range. © 2015 OSA.

Li Q.-L.,Jilin University | Gu W.-X.,Tianjin University of Technology | Gao H.,Tianjin University of Technology | Yang Y.-W.,Jilin University | Yang Y.-W.,Nanjing University
Chemical Communications | Year: 2014

In this feature article, we give an overview of the preparation and application of self-assembled architectures based on an emerging area of polymers, i.e., poly(glycidyl methacrylate)s (PGMAs) and their derivatives. A series of PGMA-based aggregates and hybrids, such as micelles, reverse micelles, capsules, nanoparticles, and inorganic-organic hybrid materials, has been constructed, and diverse morphologies were formed, driven by hydrophobic interactions, hydrogen bonding, ionic complexation, host-guest interactions, etc. In particular, the assemblies have shown great potential applications as drug vectors, gene vectors, solubilizing agents, antimicrobial agent, and so forth. Herein, the general guidelines are elaborately selected from literature examples and partially from our own. Although still in its infancy, self-assembly of PGMA-based polymers is expected to become a hot topic in polymer chemistry and materials science. © 2014 the Partner Organisations.

Alia S.M.,University of California at Riverside | Zhang G.,Jilin University | Kisailus D.,University of California at Riverside | Li D.,University of California at Riverside | And 3 more authors.
Advanced Functional Materials | Year: 2010

Porous platinum nanotubes (PtNTs) with a all thickness of 5 nm, an outer diameter of 60 nm, and a length of 520 μm are synthesized by galvanic displacement with silver nanowires, which are formed by the ethylene glycol reduction of silver nitrate. Oxygen reduction reaction (ORR) and durability experiments are conducted for PtNTs, Pt nanoparticles supported on carbon (Pt/C), and bulk polycrystalline Pt (BP-Pt) electrocatalysts to evaluate their catalytic properties for use as cathode catalysts in proton exchange membrane fuel cells. PtNTs demonstrate improved mass and specific activity for ORR and durability to Pt/C. Following durability testing, PtNTs exhibit specific ORR activity approaching that of BP-Pt. Catalyst activity for the methanol oxidation reaction (MOR) is characterized through cyclic voltammetry and chronoamperometry techniques to evaluate the materials for use as anode catalysts in direct methanol fuel cells. The PtNTs show improved specific activity for MOR and chronoamperometry characteristics over Pt/C and BP-Pt catalysts. This study focuses on the use of porous platinum nanotubes (PtNTs) with a thickness of 5 nm, an outer diameter of 60 nm, and a length of 520 μm as fuel cell catalysts. PtNTs demonstrate higher mass and specific activity for oxygen reduction and durability than the conventional platinum supported on carbon catalyst (Pt/C). PtNTs further illustrate greater specific activity and poison resistance for methanol oxidation than Pt/C and bulk platinum. © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Shi N.-Q.,Jilin Medical College | Shi N.-Q.,Peking University | Qi X.-R.,Peking University | Xiang B.,Peking University | And 3 more authors.
Journal of Controlled Release | Year: 2014

Cell-penetrating peptides (CPPs), often vividly termed as the "Trojan Horse" peptides, have attracted considerable interest for the intracellular delivery of a wide range of cargoes, such as small molecules, peptides, proteins, nucleic acids, contrast agents, nanocarriers and so on. Some preclinical and clinical developments of CPP conjugates demonstrate their promise as therapeutic agents for drug discovery. There is increasing evidence to suggest that CPPs have the potential to cross several bio-barriers (e.g., blood-brain barriers, intestinal mucosa, nasal mucosa and skin barriers). Despite revolutionary process in many aspects, there are a lot of basic issues unclear for these entities, such as internalization mechanisms, translocation efficiency, translocation kinetics, metabolic degradation, toxicity, side effect, distribution and non-specificity. Among them, non-specificity remains a major drawback for the in vivo application of CPPs in the targeted delivery of cargoes. So far, diverse organelle-specific CPPs or controlled delivery strategies have emerged and improved their specificity. In this review, we will look at the opportunities of CPPs in clinical development, bio-barriers penetration and nanocarriers delivery. Then, a series of basic problems of CPPs will be discussed. Finally, this paper will highlight the use of various controlled strategies in the organelle-specific delivery and targeted delivery of CPPs. The purpose of this review will be to emphasize most influential advance in this field and present a fundamental understanding for challenges and utilizations of CPPs. This will accelerate their translation as efficient vectors from the in vitro setting into the clinic arena, and retrieve the entry art to "Troy". © 2014 Elsevier B.V.

Han C.,Heilongjiang University | Zhang Z.,Jilin University | Xu H.,Heilongjiang University | Li J.,Heilongjiang University | And 4 more authors.
Angewandte Chemie - International Edition | Year: 2012

A series of dibenzofuran-based ternary hosts were designed and prepared. The singlet energy levels and carrier injecting/transporting abilities were adjusted on the basis of the mixed meso and short-axis linkages (see picture). By harmonizing the optical and electrical properties, the blue-emitting diodes realized highly efficient blue electrophosphorescence with ultralow driving voltages. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Chen C.,Jilin University | Song M.,University of Toledo | Xin C.,Old Dominion University | Backens J.,Christopher Newport University
IEEE Network | Year: 2013

Cognitive radio networks are a promising solution to the spectrum scarcity issue. However, cognitive radio networks are vulnerable to various kinds of security attacks, among which the jamming attack has attracted great attention as it can significantly degrade spectrum utilization. In this article we model the jamming and anti-jamming process as a Markov decision process. With this approach, secondary users are able to avoid the jamming attack launched by external attackers and therefore maximize the payoff function. We first use a policy iteration method to solve the problem. However, this approach is computationally intensive. To decrease the computation complexity, Q-function is used as an alternate method. Furthermore, we propose an algorithm to solve the Q-function. The simulation results indicate that our approach can achieve better performance than existing approaches to defend against the jamming attack. © 1986-2012 IEEE.

Lu Z.,University of California at Riverside | Li C.,University of California at Riverside | Li C.,Jilin University | Yin Y.,University of California at Riverside
Journal of Materials Chemistry | Year: 2011

A convenient route for the preparation of thermochromic VO2 particles has been developed by combining solution-phase hydrolysis and a thermal reduction process. With this method, the particle size can be easily tuned from tens to hundreds of nanometres. The liquid dispersibility of these VO2 particles facilitates convenient observation and effective measurement of the temperature-dependent optical properties in the visible region. We observe a blue shift of the resonance peak of metal-phase VO 2 particles with decreasing size. The size effect also exists in the phase transition behavior: smaller VO2 particles exhibit a wider hysteresis curve during the semiconductor-to-metal transition. We also demonstrate that the VO2 particles in the form of a colloidal dispersion can be easily incorporated into thin plastic thermochromic films that may be used as smart windows for energy management. This journal is © The Royal Society of Chemistry.

Qi W.,Jilin University | Guo Y.,Jilin University
Journal of the American Chemical Society | Year: 2011

Acid-decomposable, luminescent ZnO quantum dots (QDs) have been employed to seal the nanopores of mesoporous silica nanoparticles (MSNs) in order to inhibit premature drug (doxorubicin) release. After internalization into HeLa cells, the ZnO QD lids are rapidly dissolved in the acidic intracellular compartments, and as a result, the loaded drug is released into the cytosol from the MSNs. The ZnO QDs behave as a dual-purpose entity that not only acts as a lid but also has a synergistic antitumor effect on cancer cells. We anticipate that these nanoparticles may prove to be a significant step toward the development of a pH-sensitive drug delivery system that minimizes drug toxicity. © 2011 American Chemical Society.

Alper J.P.,University of California at Berkeley | Wang S.,University of California at Berkeley | Wang S.,Jilin University | Rossi F.,CNR Institute of Materials for Electronics and Magnetism | And 4 more authors.
Nano Letters | Year: 2014

Microsupercapacitors are attractive energy storage devices for integration with autonomous microsensor networks due to their high-power capabilities and robust cycle lifetimes. Here, we demonstrate porous silicon nanowires synthesized via a lithography compatible low-temperature wet etch and encapsulated in an ultrathin graphitic carbon sheath, as electrochemical double layer capacitor electrodes. Specific capacitance values reaching 325 mF cm -2 are achieved, representing the highest specific ECDL capacitance for planar microsupercapacitor electrode materials to date. © 2014 American Chemical Society.

Chen J.,Jilin University | Chen J.,Changchun Normal University | Wang X.,Jilin University | Cui X.,Jilin University | And 2 more authors.
Chemical Communications | Year: 2014

An amorphous metal-free N-doped carbon film prepared by sputtering and annealing exhibits comparable electrocatalytic activity and superior stability and methanol tolerance to the commercial Pt/C catalyst via a four-electron pathway for oxygen reduction reaction (ORR). Pyridinic nitrogen in films plays a key role in electrocatalytic activity for ORR. This journal is © The Royal Society of Chemistry 2014.

Wang L.,Peking University | Wang L.,Jilin University | Du Y.,Key Laboratory of Carcinogenesis and Translational Research | Lu M.,Peking University | Li T.,Peking University
Nucleic Acids Research | Year: 2012

Protein lysine acetylation plays an important role in the normal functioning of cells, including gene expression regulation, protein stability and metabolism regulation. Although large amounts of lysine acetylation sites have been identified via large-scale mass spectrometry or traditional experimental methods, the lysine (K)-acetyl-transferase (KAT) responsible for the acetylation of a given protein or lysine site remains largely unknown due to the experimental limitations of KAT substrate identification. Hence, the in silico prediction of KAT-specific acetylation sites may provide direction for further experiments. In our previous study, we developed the acetylation set enrichment based (ASEB) computer program to predict which KAT-families are responsible for the acetylation of a given protein or lysine site. In this article, we provide KAT-specific acetylation site prediction as a web service. This web server not only provides the online tool and R package for the method in our previous study, but several useful services are also included, such as the integration of protein-protein interaction information to enhance prediction accuracy. This web server can be freely accessed at huac. © 2012 The Author(s).

Liu C.,CAS Institute of Chemistry | Gao Z.,Jilin University | Zeng J.,CAS Institute of Chemistry | Hou Y.,CAS Institute of Chemistry | And 7 more authors.
ACS Nano | Year: 2013

Detection of early malignant tumors remains clinically difficult; developing ultrasensitive imaging agents is therefore highly demanded. Owing to the unusual magnetic and optical properties associated with f-electrons, rare-earth elements are very suitable for creating functional materials potentially useful for tumor imaging. Nanometer-sized particles offer such a platform with which versatile unique properties of the rare-earth elements can be integrated. Yet the development of rare-earth nanoparticle-based tumor probes suitable for imaging tiny tumors in vivo remains difficult, which challenges not only the physical properties of the nanoparticles but also the rationality of the probe design. Here we report new approaches for size control synthesis of magnetic/upconversion fluorescent NaGdF4:Yb,Er nanocrystals and their applications for imaging tiny tumors in vivo. By independently varying F-:Ln3+ and Na+:Ln3+ ratios, the size and shape regulation mechanisms were investigated. By replacing the oleic acid ligand with PEG2000 bearing a maleimide group at one end and two phosphate groups at the other end, PEGylated NaGdF4:Yb,Er nanoparticles with optimized size and upconversion fluorescence were obtained. Accordingly, a dual-modality molecular tumor probe was prepared, as a proof of concept, by covalently attaching antitumor antibody to PEGylated NaGdF4:Yb,Er nanoparticles through a "click" reaction. Systematic investigations on tumor detections, through magnetic resonance imaging and upconversion fluorescence imaging, were carried out to image intraperitoneal tumors and subcutaneous tumors in vivo. Owing to the excellent properties of the molecular probes, tumors smaller than 2 mm was successfully imaged in vivo. In addition, pharmacokinetic studies on differently sized particles were performed to disclose the particle size dependent biodistributions and elimination pathways. © 2013 American Chemical Society.

Xue Y.,Jilin University | Matuszewski M.,Instytut Fizyki Polskiej Akademii Nauk
Physical Review Letters | Year: 2014

We predict the existence of a self-localized solution in a nonresonantly pumped exciton-polariton condensate. The solution has a shape resembling the well-known hyperbolic tangent profile of a dark soliton, but exhibits several distinct features. We find that it performs small oscillations, which are transformed into "soliton explosions" at lower pumping intensities. Moreover, after hundreds or thousands of picoseconds of apparently stable evolution the soliton decays abruptly, which is explained by the acceleration instability found previously in the Bekki-Nozaki hole solutions of the complex Ginzburg-Landau equation. We show that the soliton can be formed spontaneously from a small seed in the polariton field or by using spatial modulation of the pumping profile. © 2014 American Physical Society.

Liang S.,Changchun Normal University | Liang S.,Jilin University | Zhang J.,Nanjing Normal University
Nonlinear Analysis: Real World Applications | Year: 2014

In this paper, we consider the existence and multiplicity of solutions of Kirchhoff type problems with critical nonlinearity in R3:- ε2(a+b∫R3|u|2dx) Δu+V(x)u=K(x)|u|4u+h(x,u), (t,x) â̂̂R×R3. Under suitable assumptions, we prove that this has at least one solution and for any mâ̂̂N, it has at least m pairs of solutions. © 2013 Elsevier Ltd. All rights reserved.

Wei Y.,Jilin University | Yang M.,Zhejiang Normal University
Zeitschrift fur Angewandte Mathematik und Physik | Year: 2014

In this paper, we consider the existence and multiplicity of homoclinic type solutions to a system of diffusion equations with spectrum point zero. By using some recent critical point theorems for strongly indefinite problems, we obtain at least one nontrivial solution and also infinitely many solutions. © 2013 Springer Basel.

Tong X.,China Institute of Technology | Dai M.-J.,China Institute of Technology | Zhang Z.-H.,Jilin University
Applied Surface Science | Year: 2013

In this study, the selective laser surface melting and laser surface alloying technologies were adopted to improve the thermal fatigue resistance of medium carbon hot-work die steel (H13) by a CO2 laser. Two kinds of mixed chromium (Cr) and nickel (Ni) powders were used as the laser alloying materials, and the effects of the mixing ratio on the thermal fatigue resistance were investigated thoroughly. Some important results such as cross-sectional morphology, phases, hardness and thermal fatigue behavior were analyzed and evaluated. It indicates that the laser surface alloying technique using mixed powder with ratio of 75%Cr-25%Ni can considerably enhance the thermal fatigue resistance of the H13 steel. The laser alloyed zone has excellent properties such as preventing crack initiation and oxidation corrosion compared with original H13. Thermal cracking and oxidation corrosion that occurred at substrate surface can be surrounded and intercepted by a gridded laser strengthened structure. Therefore, the naturally developed cracks could be effectively prevented. Theses results and analysis show that laser surface technique can be positively used to improve surface mechanical properties of H13 dies. © 2013 Elsevier B.V.

Liu F.,Zhejiang University | Wang L.,Jilin University | Sun Q.,Zhejiang University | Zhu L.,Jilin University | And 2 more authors.
Journal of the American Chemical Society | Year: 2012

Homogeneous catalysts usually show higher catalytic activities than heterogeneous catalysts because of their high dispersion of catalytically active sites. We demonstrate here that heterogeneous catalysts of ionic liquids functionalized on superhydrophobic mesoporous polymers exhibit much higher activities in transesterification to form biodiesel than homogeneous catalysts of the ionic liquids themselves. This phenomenon is strongly related to the unique features of high enrichment and good miscibility of the superhydrophobic mesoporous polymers for the reactants. These features should allow the design and development of a wide variety of catalysts for the conversion of organic compounds. © 2012 American Chemical Society.

Zhao Q.,National University of Singapore | Tan P.,National University of Singapore | Dai Q.,Jilin University | Shen L.,Institute for Infocomm Research | And 2 more authors.
IEEE Transactions on Pattern Analysis and Machine Intelligence | Year: 2012

We propose a method for intrinsic image decomposition based on retinex theory and texture analysis. While most previous methods approach this problem by analyzing local gradient properties, our technique additionally identifies distant pixels with the same reflectance through texture analysis, and uses these nonlocal reflectance constraints to significantly reduce ambiguity in decomposition. We formulate the decomposition problem as the minimization of a quadratic function which incorporates both the retinex constraint and our nonlocal texture constraint. This optimization can be solved in closed form with the standard conjugate gradient algorithm. Extensive experimentation with comparisons to previous techniques validate our method in terms of both decomposition accuracy and runtime efficiency. © 2012 IEEE.

Han C.,Heilongjiang University | Xie G.,Jilin University | Xu H.,Heilongjiang University | Zhang Z.,Jilin University | And 4 more authors.
Advanced Materials | Year: 2011

Highly efficient white organic light-emitting diodes (WOLEDs) with a simple, single-host-based structure are fabricated to realize the state-of-the-art performance of extremely low driving voltages, high efficiencies, and low efficiency roll-offs. This is the first single-host-based WOLED with both high efficiency and extremely low operating voltage at practical luminescence, demonstrating the great potential of these WOLEDs for portable display and lighting applications. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Home > Press > Quantum effects affect the best superconductor: Quantum effects explain why hydrogen sulphide is a superconductor at record-breaking temperatures Abstract: The theoretical results of a piece of international research published in Nature, whose first author is Ion Errea, a researcher at the UPV/EHU and DIPC, suggest that the quantum nature of hydrogen (in other words, the possibility of it behaving like a particle or a wave) considerably affects the structural properties of hydrogen-rich compounds (potential room-temperature superconducting substances). This is in fact the case of the superconductor hydrogen sulphide: a stinking compound that smells of rotten eggs, which when subjected to pressures a million times higher than atmospheric pressure, behaves like a superconductor at the highest temperature ever identified. This new advance in understanding the physics of high-temperature superconductivity could help to drive forward progress in the search for room-temperature superconductors, which could be used in levitating trains or next-generation supercomputers, for example. Superconductors are materials that carry electrical current with zero electrical resistance. Conventional or low-temperature ones behave that way only when the substance is cooled down to temperatures close to absolute zero (-273 °C o 0 degrees Kelvin). Last year, however, German researchers identified the high-temperature superconducting properties of hydrogen sulphide which makes it the superconductor at the highest temperature ever discovered: -70 °C or 203 K. The structure of the chemical bonds between atoms changes In classical or Newtonian physics it is possible to measure the position and momentum of a moving object to determine where it is going and how long it will take to reach its destination. These two properties are inherently linked. However, in the strange world of quantum physics, it is impossible, according to Heisenberg's uncertainty principle, for specific pairs of observable complementary physical magnitudes of a particle to be known at the same time. Hydrogen is the lightest element in the periodic table, so it is an atom that is very strongly affected by quantum behaviour. Its quantum nature affects the structural and physical properties of various hydrogen compounds. An example is high-pressure ice where quantum fluctuations of the proton lead to a change in the way the molecules are held together, due to the fact that the chemical bonds between atoms end up being symmetrical. The researchers in this study believe that a similar quantum hydrogen-bond symmetrisation occurs in the hydrogen sulphide superconductor. The researchers have formulated the calculations by considering the hydrogen atoms as quantum particles behaving like waves, and they have concluded that they form symmetrical bonds at a pressure similar to that used experimentally by the German researchers. So they have succeeded in explaining the phenomenon of superconductivity at record-breaking temperatures because in previous calculations hydrogen atoms were treated as classical particles, which made impossible to explain the experiment. All this highlights the fact that quantum physics and symmetrical hydrogen bonds lie behind high-temperature conductivity in hydrogen sulphide. The researchers are delighted that the good results obtained in this research show that quantitative predictions and computation can be used with complete confidence to speed up the discovery of high-temperature superconductors. According to the calculations made, the quantum symmetrisation of the hydrogen bonds has a great impact on the vibrational and superconducting properties of hydrogen sulphide. "In order to theoretically reproduce the observed pressure dependence of the superconducting critical temperature, the quantum symmetrisation needs to be taken into account," explained Ion Errea, the lead researcher in the study. This theoretical study shows that in hydrogen-rich compounds, the quantum motion of hydrogen can strongly affect the structural properties (even modifying the chemical bonding), as well as the electron-phonon interaction that drives the superconducting transition. In the view of the researchers, theory and computation have played a key role in the search for superconducting hydrides subjected to extreme compression. And they also pointed out that in the future an attempt will be made to increase the temperature until room-temperature superconductivity is achieved while dramatically reducing the pressures required. ### Additional information This international research was carried out with the collaboration of researchers from the UPV/EHU-University of the Basque Country and Donostia International Physics Center (DIPC), the UPMC Université Paris 06 (Sorbonne), the University of Cambridge (Cavendish Laboratory), the Jiangsu Normal University, the Carnegie Institution of Washington, Jilin University, and the University of Rome 'La Sapienza'. The lead researcher in the study was Ion Errea (Donostia-San Sebastian, 1984); he is a PhD holder in Physics and is currently a researcher at DIPC and a lecturer in the UPV/EHU's Department of Applied Physics. For more information, please click If you have a comment, please us. Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Horsley S.A.R.,University of Exeter | Wu J.-H.,Jilin University | Artoni M.,Instituto Nazionale Of Ottica | Artoni M.,CNR Institute of Acoustics and Sensors Orso Mario Corbino | La Rocca G.C.,Normal School of Pisa
Physical Review Letters | Year: 2013

Reciprocity is fundamental to light transport and is a concept that holds also in rather complex systems. Yet, reciprocity can be switched off even in linear, isotropic, and passive media by setting the material structure into motion. In highly dispersive multilayers this leads to a fairly large forward-backward asymmetry in the pulse transmission. Moreover, in multilevel systems, this transport phenomenon can be all-optically enhanced. For atomic multilayer structures made of three-level cold Rb87 atoms, for instance, forward-backward transmission contrast around 95% can be obtained already at atomic speeds in the meter per second range. The scheme we illustrate may open up avenues for optical isolation that were not previously accessible. © 2013 American Physical Society.

Su J.,Shanghai JiaoTong University | Zou X.,Jilin University | Chen J.-S.,Shanghai JiaoTong University
RSC Advances | Year: 2014

The defect chemistry of metal oxides is a very important research aspect of inorganic solid-state materials. This is because (i) a certain amount of defects or imperfections are always present in metal oxide materials; (ii) the presence of defects affects, and even sometimes determines, the physical and chemical properties of the materials; and (iii) more importantly, defects do not necessarily have adverse effects on the properties of materials, and judicious "defect engineering" can bring about improved properties desired in material systems, and even some new useful functionalities that are not available to the "perfect" material. In this review, we specially highlight the recent research efforts toward understanding the defect chemistry of titanium dioxide (also known as titania, TiO2), a widely-studied multifunctional metal oxide. In the discussion, particular attention is paid to the synthesis of Ti3+/oxygen vacancy self-modified TiO2 materials and the favorable effects of these defects on the materials' properties and applications. This review, focusing on a representative metal oxide (i.e., TiO2), is anticipated to provide some new insights into the general defect chemistry of metal oxides, and to give impetus to the development of the "defect engineering" of metal oxide materials. © 2014 The Royal Society of Chemistry.

Li L.-L.,University of Illinois at Urbana - Champaign | Zhang R.,University of Illinois at Urbana - Champaign | Yin L.,University of Illinois at Urbana - Champaign | Zheng K.,Jilin University | And 3 more authors.
Angewandte Chemie - International Edition | Year: 2012

Coat of lipids: Water-dispersible and functionalizable upconverting nanoparticles (UCNPs) for selective imaging of live cancer cells were synthesized. The synthetic approach involves coating the surface of the UCNPs with a monolayer of phospholipids that contain different functional groups (see picture), thus allowing for conjugation of many molecules for applications in fields such as bioinspired nanoassembly, biosensing, and biomedicine. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Guo X.,Jilin University | Song W.,Jilin University | Chen C.,University of Maine, United States | Di W.,Jilin University | Qin W.,Jilin University
Physical Chemistry Chemical Physics | Year: 2013

A novel near-infrared (NIR)-responsive photocatalyst, β-NaYF 4:Yb3+,Tm3+@ZnO composites, was prepared by a two-step high temperature thermolysis method. In the NIR-responsive photocatalysis, β-NaYF4:Yb,Tm served as a NIR-to-UV upconverter and provided "UV light" or "necessary energy" to the ZnO catalyst. The energy transfer in the composites and the mixtures of β-NaYF4:Yb,Tm and ZnO was studied by using steady-state and dynamic fluorescence spectroscopy. The NIR photocatalytic activities were investigated by the decomposition of Rhodamine B. It was found that the energy transfer processes dominated the overall photocatalytic activities, and the generation of hydroxyl radicals was the origin of organic pollutant decomposition under NIR irradiation. This journal is © the Owner Societies 2013.

Qi D.,Chang'an University | Leick M.,University of Illinois at Urbana - Champaign | Liu Y.,Jilin University | Lee C.-F.F.,University of Illinois at Urbana - Champaign
Fuel | Year: 2011

In this study, the effect of injection timing and EGR rate on the combustion and emissions of a Ford Lion V6 split injection strategy direct injection diesel engine has been experimentally investigated by using neat biodiesel produced from soybean oil. The results showed that, with the increasing of EGR rate, the brake specific fuel combustion (BSFC) and soot emission were slightly increased, and nitrogen oxide (NOx) emission was evidently decreased. Under higher EGR rate, the peak pressure was slightly lower, and the peak heat release rate kept almost identical at lower engine load, and was higher at higher engine load. With the main injection timing retarded, BSFC was slightly increased, NOx emission was evidently decreased, and soot emission hardly varied. The second peak pressure was evidently decreased and the heat release rate was slightly increased. © 2010 Elsevier Ltd. All rights reserved.

Zhu S.,Jilin University | Ma Z.,Shanghai JiaoTong University
Physics Letters, Section A: General, Atomic and Solid State Physics | Year: 2010

In this Letter, we study various physically important topologies on the set S (H) of states of standard quantum mechanics, and find the relationship between them. Our result extends the results in S. Bugajski (1994) [11]. © 2010 Elsevier B.V. All rights reserved.

Yu T.,Jilin University | Yu T.,Heilongjiang University
Systems and Control Letters | Year: 2011

This paper deals with the transmission problem in simultaneous stabilization of time-varying linear systems. We establish two criteria for the transitivity in simultaneous stabilization. In particular, we give a necessary and sufficient condition for certain linear systems to satisfy a strengthened version of transitivity. © 2010 Elsevier B.V. All rights reserved.

Sun L.,Heilongjiang University | Tian C.,Heilongjiang University | Fu Y.,Jilin University | Yang Y.,Heilongjiang University | And 3 more authors.
Chemistry - A European Journal | Year: 2014

An advanced supercapacitor material based on nitrogen- doped porous graphitic carbon (NPGC) with high a surface area was synthesized by means of a simple coordination- pyrolysis combination process, in which tetraethyl orthosilicate (TEOS), nickel nitrate, and glucose were adopted as porogent, graphitic catalyst precursor, and carbon source, respectively. In addition, melamine was selected as a nitrogen source owing to its nitrogen-enriched structure and the strong interaction between the amine groups and the glucose unit. A low-temperature treatment resulted in the formation of a NPGC precursor by combination of the catalytic precursor, hydrolyzed TEOS, and the melamine-glucose unit. Following pyrolysis and removal of the catalyst and porogent, the NPGC material showed excellent electrical conductivity owing to its high crystallinity, a large Brunauer- Emmett-Teller surface area (SBET=1027 m2g-1), and a high nitrogen level (7.72 wt%). The unusual microstructure of NPGC materials could provide electrochemical energy storage. The NPGC material, without the need for any conductive additives, showed excellent capacitive behavior (293 Fg-1 at 1 Ag-1), long-term cycling stability, and high coulombic efficiency (>99.9% over 5000 cycles) in KOH when used as an electrode. Notably, in a two-electrode symmetric supercapacitor, NPGC energy densities as high as 8.1 and 47.5 Whkg-1, at a high power density (10.5 kWkg-1), were achieved in 6m KOH and 1m Et4NBF4-PC electrolytes, respectively. Thus, the synthesized NPGC material could be a highly promising electrode material for advanced supercapacitors and other conversion devices. © 2014 Wiley-VCH Verlag GmbH& Co. KGaA, Weinheim.

Liu L.,University of Connecticut | Liu S.,Jilin University
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing | Year: 2014

The stepped-frequency continuous wave (SFCW) radar technique was used to detect cardio-respiratory signals as the vital sign from a human subject positioned behind obstacles under laboratory conditions. The experiments were organized with a number of detection scenarios by collecting data from a group of human subjects. The experiments also investigated the effect of varying thickness of the obstacles, human subject postures, status of breathing, position of radar antenna relative to human subject's chest, as well as the length of survey times. The experimental results have shown that respiration as the primary vital sign can be detected with very high confidence and should be highlighted in developing radar systems for search and rescue for earthquake disaster survivors. Among the four human subject postures of face up, face down, face left, and face right, detection of the cardiologic signals can solely be achieved possibly when the subject was facing up. When the radar antennas to be placed at certain offset, not directly above the human subject's chest, it is still possible for good detection of the breathing signal. The minimum recording time for extracting respiration signal can be as short as 5 s. Even be conservative, a period of 30 s should be long enough for catching the respiratory signal with high signal to noise ratio. © 2008-2012 IEEE.

Song W.,Jilin University | Mano J.F.,University of Minho | Mano J.F.,European Institute of Excellence on Tissue Engineering and Regenerative Medicine
Soft Matter | Year: 2013

Regulation of protein adsorption and cell adhesion on surfaces is a key aspect in the field of biomedicine and tissue engineering. Beside the general studies on hydrophilic/hydrophobic surfaces, there are both fundamental and practical interests to extend the investigation of the interaction between proteins or cells and surfaces to the two extreme wettability ranges, namely superhydrophilicity and superhydrophobicity. This review gave an overview of recent studies on proteins or cells action on these two special wettability ranges. The first part will focus on the interaction between proteins and superhydrophilic/superhydrophobic surfaces. The second part will focus on cells adhesion on these extreme wettable surfaces. Surfaces can be patterned to control in space the wettability within extreme values. As an application of such substrates, flat chips for high-throughput screening are also addressed to offer new insight on the design of a new type of bioanalysis supports. © 2013 The Royal Society of Chemistry.

Liu Y.,Shanghai JiaoTong University | Yu C.,Shanghai JiaoTong University | Jin H.,Shanghai JiaoTong University | Jiang B.,Shanghai JiaoTong University | And 4 more authors.
Journal of the American Chemical Society | Year: 2013

Herein, we report a novel Janus particle and supramolecular block copolymer consisting of two chemically distinct hyperbranched polymers, which is coined as Janus hyperbranched polymer. It is constructed by the noncovalent coupling between a hydrophobic hyperbranched poly(3-ethyl-3-oxetanemethanol) with an apex of an azobenzene (AZO) group and a hydrophilic hyperbranched polyglycerol with an apex of a β-cyclodextrin (CD) group through the specific AZO/CD host-guest interactions. Such an amphiphilic supramolecular polymer resembles a tree together with its root very well in the architecture and can further self-assemble into unilamellar bilayer vesicles with narrow size distribution, which disassembles reversibly under the irradiation of UV light due to the trans-to-cis isomerization of the AZO groups. In addition, the obtained vesicles could further aggregate into colloidal crystal-like close-packed arrays under freeze-drying conditions. The dynamics and mechanism for the self-assembly of vesicles as well as the bilayer structure have been disclosed by a dissipative particle dynamics simulation. © 2013 American Chemical Society.

Bo Y.,Jilin University | Liu J.,Hong Kong Baptist University | Feng J.,University of Warwick
IEEE Transactions on Knowledge and Data Engineering | Year: 2012

Network communities refer to groups of vertices within which their connecting links are dense but between which they are sparse. A network community mining problem (or NCMP for short) is concerned with the problem of finding all such communities from a given network. A wide variety of applications can be formulated as NCMPs, ranging from social and/or biological network analysis to web mining and searching. So far, many algorithms addressing NCMPs have been developed and most of them fall into the categories of either optimization based or heuristic methods. Distinct from the existing studies, the work presented in this paper explores the notion of network communities and their properties based on the dynamics of a stochastic model naturally introduced. In the paper, a relationship between the hierarchical community structure of a network and the local mixing properties of such a stochastic model has been established with the large-deviation theory. Topological information regarding to the community structures hidden in networks can be inferred from their spectral signatures. Based on the above-mentioned relationship, this work proposes a general framework for characterizing, analyzing, and mining network communities. Utilizing the two basic properties of metastability, i.e., being locally uniform and temporarily fixed, an efficient implementation of the framework, called the LM algorithm, has been developed that can scalably mine communities hidden in large-scale networks. The effectiveness and efficiency of the LM algorithm have been theoretically analyzed as well as experimentally validated.

Wu Y.-L.,Guangdong General Hospital and Guangdong Academy of Medical science | Zhou C.,Shanghai Pulmonary Hospital | Hu C.-P.,Central South University | Feng J.,Jiangsu Provincial Tumor Hospital | And 11 more authors.
The Lancet Oncology | Year: 2014

Background: Afatinib-an oral irreversible ErbB family blocker-improves progression-free survival compared with pemetrexed and cisplatin for first-line treatment of patients with EGFR mutation-positive advanced non-small-cell lung cancer (NSCLC). We compared afatinib with gemcitabine and cisplatin-a chemotherapy regimen widely used in Asia-for first-line treatment of Asian patients with EGFR mutation-positive advanced NSCLC. Methods: This open-label, randomised phase 3 trial was done at 36 centres in China, Thailand, and South Korea. After central testing for EGFR mutations, treatment-naive patients (stage IIIB or IV cancer [American Joint Committee on Cancer version 6], performance status 0-1) were randomly assigned (2:1) to receive either oral afatinib (40 mg per day) or intravenous gemcitabine 1000 mg/m2 on day 1 and day 8 plus cisplatin 75 mg/m2 on day 1 of a 3-week schedule for up to six cycles. Randomisation was done centrally with a random number-generating system and an interactive internet and voice-response system. Randomisation was stratified by EGFR mutation (Leu858Arg, exon 19 deletions, or other; block size three). Clinicians and patients were not masked to treatment assignment, but the independent central imaging review group were. Treatment continued until disease progression, intolerable toxic effects, or withdrawal of consent. The primary endpoint was progression-free survival assessed by independent central review (intention-to-treat population). This study is registered with, NCT01121393. Findings: 910 patients were screened and 364 were randomly assigned (242 to afatinib, 122 to gemcitabine and cisplatin). Median progression-free survival was significantly longer in the afatinib group (11·0 months, 95% CI 9·7-13·7) than in the gemcitabine and cisplatin group (5·6 months, 5·1-6·7; hazard ratio 0·28, 95% CI 0·20-0·39; p<0·0001). The most common treatment-related grade 3 or 4 adverse events in the afatinib group were rash or acne (35 [14·6%] of 239 patients), diarrhoea (13 [5·4%]), and stomatitis or mucositis (13 [5·4%]), compared with neutropenia (30 [26·5%] of 113 patients), vomiting (22 [19·5%]), and leucopenia (17 [15·0%]) in the gemcitabine and cisplatin group. Treatment-related serious adverse events occurred in 15 (6·3%) patients in the afatinib group and nine (8·0%) patients in the gemcitabine and cisplatin group. Interpretation: First-line afatinib significantly improves progression-free survival with a tolerable and manageable safety profile in Asian patients with EGFR mutation-positive advanced lung NSCLC. Afatinib should be considered as a first-line treatment option for this patient population. Funding: Boehringer Ingelheim. © 2014 Elsevier Ltd.

Yuan B.,CAS Changchun Institute of Applied Chemistry | Zheng C.,Heilongjiang University | Teng H.,Jilin University | You T.,CAS Changchun Institute of Applied Chemistry
Journal of Chromatography A | Year: 2010

A rapid and simple method was demonstrated for the analysis of atropine, anisodamine, and scopolamine by nonaqueous capillary electrophoresis (NACE) coupled with electrochemiluminescence (ECL) and electrochemistry (EC) dual detection. The mixture of acetonitrile (ACN) and 2-propanol containing 1 M acetic acid (HAc), 20 mM sodium acetate (NaAc), and 2.5 mM tetrabutylammonium perchlorate (TBAP) was used as the electrophoretic buffer. Although a short capillary of 18 cm was used, the decoupler was not needed and the separation efficiency was good. The linear ranges of atropine, anisodamine, and scopolamine were 0.5-50, 5-2000, and 50-2000 μM, respectively. For six replicate measurements of 100 μM scopolamine, 15 μM atropine, and 200 μM anisodamine, the RSDs of ECL intensity, EC current, and migration time were less than 3.6%, 4.5%, and 0.3%, respectively. In addition, because the organic buffer was used, the working electrode (Pt) was not easily fouled and did not need reactivation. The method was also applied for the determination of these three alkaloids in Flos daturae extract. © 2009 Elsevier B.V. All rights reserved.

News Article | October 30, 2015

Whispering-Gallery-Mode (WGM) microcavities that confine light in a small volume with high quality (Q) factors and enhance interaction of light with matters inside the cavity have shown promising applications as an element for a variety of devices such as micro-lasers, micro-sensors, micro-filters, and thus are becoming the basic building blocks of integrated photonic systems. This leads to tremendous progress in the development of micro-scale high-Q microcavity processing technologies. In a review entitled "Femtosecond laser 3D fabrication of whispering-gallery-mode microcavities" by Huailiang Xu and Hongbo Sun at the State Key Laboratory on Integrated Optoelectronics, Jilin University, recent progress in femtosecond laser three-dimensional fabrications of optical WGM microcavities was overviewed. This review was published in Science China Physics, Mechanics & Astronomy (volume 58, Issue 11). Femtosecond laser direct writing has attracted a lot of attention in recent years, and demonstrated the versatility in fabrication of a variety of devices from micro-fluidics, optoelectronics, micro-electronics, micro-machines, micro-sensing, to micro-biomimetics and micro-optics, etc. However, the reports on the fabrication of high-Q WGM microcavities appeared only recently. This review article began with a brief introduction of the basic principle of femtosecond laser processing, in which the 3D capability of high-quality micro-fabrication of femtosecond laser processing technique is discussed. Subsequently, the fabrications of 3D passive and active WGMs microcavities in a variety of materials including polymer, glass and crystals were demonstrated. The fabrication of the integrated device of a micro-sensor incorporated with WGM microcavity was also introduced. They pointed out that fabricating microcavities with extremely high Q factors in the range of 108-1010 by using femtosecond laser direct writing is still challenging. However, "it is believed," the two researchers said, "the further effort on the investigation of femtosecond laser 3D fabrication of high-Q factor microcavities will undoubtedly benefit the applications of microcavities in a broad spectrum from bio-sensing and optoelectronics to quantum information.." Explore further: Plasmonic whispering gallery microcavity paves the way to future nanolasers More information: HuaiLiang Xu et al. Femtosecond laser 3D fabrication of whispering-gallery-mode microcavities, Science China Physics, Mechanics & Astronomy (2015). DOI: 10.1007/s11433-015-5720-5

Zhou T.,Jilin University | Jia T.,Jilin University | Kang B.,Jilin University | Li F.,Jilin University | And 2 more authors.
Advanced Energy Materials | Year: 2011

The development of non-fullerene-based electron acceptors (especially organic molecules with sufficient absorption property within the solar spectrum region) for bulk-heterojunction (BHJ) organic solar cells (OSCs) is an important issue for the achievement of high photoconversion efficiency. In this contribution, a new class of organic acceptors di-cyan substituted quinacridone derivatives (DCN-n CQA, n = 4, 6 and 8) for BHJ solar cells was designed and synthesized. DCN-n CQA molecules possess facile synthesis, solution processability, visible and near-IR light absorption and relatively stable characteristics. The DCN-8CQA molecule exhibited a proper LUMO energy level (-4.1 eV), small bandgap (1.8 eV) and moderate electron mobility (10 -4 cm 2 V -1 S -1), suggesting that this molecule is an ideal acceptor material for the classical donor material regio-regular poly (3-hexylthiophene) (P3HT). A photovoltaic device with a structure of [ITO/PEDOT:PSS/P3HT:DCN-8CQA/LiF/Al] displayed a power conversion efficiency of 1.57% and a fill factor of 57% under 100 mW cm -2 AM 1.5G simulated solar illumination. The DCN-n CQA molecules showed remarkable absorption in the region from 650 to 700 nm, where P3HT has a weak absorption promoting overlap with the solar spectrum and potentially improving the performance of the solar cell. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Wang X.,Jilin University | Deng X.,Beihang University | Zhang X.,Jilin University
PLoS ONE | Year: 2014

Amelogenin, the major enamel matrix protein in tooth development, has been demonstrated to play a significant role in tooth enamel formation. Previous studies have identified the alternative splicing of amelogenin in many mammalian vertebrates as one mechanism for amelogenin heterogeneous expression in teeth. While amelogenin and its splicing forms in mammalian vertebrates have been cloned and sequenced, the amelogenin gene, especially its splicing forms in nonmammalian species, remains largely unknown. To better understand the mechanism underlying amelogenin evolution, we previously cloned and characterized an amelogenin gene sequence from a squamate, the green iguana. In this study, we employed RT-PCR to amplify the amelogenin gene from the black spiny-tailed iguana Ctenosaura similis teeth, and discovered a novel splicing form of the amelogenin gene. The transcript of the newly identified iguana amelogenin gene (named C. Similis-T2L) is 873 nucleotides long encoding an expected polypeptide of 206 amino acids. The C. Similis-T2L contains a unique exon denominated exon X, which is located between exon 5 and exon 6. The C. Similis-T2L contains 7 exons including exon 1, 2, 3, 5, X, 6, and 7. Analysis of the secondary and tertiary structures of T2L amelogenin protein demonstrated that exon X has a dramatic effect on the amelogenin structures. This is the first report to provide definitive evidence for the amelogenin alternative splicing in non-mammalian vertebrates, revealing a unique exon X and the splicing form of the amelogenin gene transcript in Ctenosaura similis. © 2012 Wang et al.

Li D.,Jilin University | Li D.,Hong Kong University of Science and Technology | Liu J.,Hong Kong University of Science and Technology | Kwok R.T.K.,Hong Kong University of Science and Technology | And 3 more authors.
Chemical Communications | Year: 2012

Mesoporous SBA-15 functionalized with aggregation-induced emission (AIE) luminogens serves as an efficient and recyclable fluorescent sensor for the detection of picric acid (PA), with a quenching constant of up to 2.5 × 10 5 M -1 in a water solution, presenting a new model for the supersensitive detection of explosives. © 2012 The Royal Society of Chemistry.

Qi Z.,Jilin University | Qi Z.,Jilin Institute of Architecture and Civil Engineering | Gao Q.,Jilin University | Liu Y.,Jilin University | And 2 more authors.
Renewable and Sustainable Energy Reviews | Year: 2014

Hybrid energy systems (HES) facilitate the efficient utilization of renewable resources and sustainable energy, and they are expected to be more prevalent in the future. With ground source heat pump (GSHP) as the main body and core technology, the hybrid ground source heat pump (HGSHP) system is used frequently in recent years and its integration and synthesis skills face higher requirements. The worldwide hybrid system has usually been composed of types of energy source devices, such as solar collector, boiler (coal, gas, oil), electric heater, waste energy device, cooling tower, cooler, and thermal storage system with natural cold and hot. Actually, they lead to the complicated unsteady processes and various hybrid energy systems. In China, the applications of these systems are growing year by year, but the new technology breakthrough is being in difficulty and even in an awkward situation. This paper review the progress of GSHP combined with HES all over the world, and surveyed the development of HGSHP in China. Meanwhile, the basic proposals for development in the future are presented to make up the gap in the field of HES and HGSHP. A coming work aims to research the basic problems during the demonstration application, such as investigation of system design parameters, component configuration and control strategies of a HGSHP system. These problems will strengthen theoretical and practical understanding of HES and facilitate more extensive application of HGSHP in China. © 2013 Elsevier Ltd.

Shao Y.-H.,Zhejiang University of Technology | Wang Z.,Jilin University | Chen W.-J.,Zhejiang University of Technology | Deng N.-Y.,China Agricultural University
Knowledge-Based Systems | Year: 2013

For the recently proposed projection twin support vector machine (PTSVM) [1], we propose a simpler and reasonable variant from theoretical point of view, called projection twin support vector machine with regularization term, RPTSVM for short. Note that only the empirical risk minimization is introduced in primal problems of PTSVM, incurring the possible singularity problems. Our RPTSVM reformulates the primal problems by adding a maximum margin regularization term, and, therefore, the singularity is avoided and the regularized risk principle is implemented. In addition, the nonlinear classification ignored in PTSVM is also considered in our RPTSVM. Further, a successive overrelaxation technique and a genetic algorithm are introduced to solve our optimization problems and to do the parameter selection, respectively. Computational comparisons of our RPTSVM against original PTSVM, TWSVM and MVSVM indicate that our RPTSVM obtains better generalization than others. © 2012 Elsevier B.V. All rights reserved.

Wang G.,Hong Kong University of Science and Technology | Wang G.,Jilin University | Zhang T.-Y.,Hong Kong University of Science and Technology
Journal of Colloid and Interface Science | Year: 2012

Hierarchical nanostructured CuO surface was embellished to amplify the wettability. The pristine superhydrophilic CuO surface spontaneously transited to be superhydrophobic after exposed in air at room temperature for about 3. weeks. The wettability change is attributed to the adsorption of oxygen molecules on the topmost layer according to the surface chemical analysis. The adsorbed oxygen molecules could be removed by dipping the sample into l-Ascorbic acid solution for 10. s, leading to the recovery of the pristine superhydrophilicity. © 2012 Elsevier Inc..

Di J.,Jilin University | Zhao Y.,Beihang University | Yu J.,Jilin University
Journal of Materials Chemistry | Year: 2011

Molecular sieves, such as zeolites and mesoporous materials, have been widely used in the fields of catalysis, adsorption, ion-exchange, and are finding new applications in optics, electronics, magnetism, medicine, etc. Molecular sieves with different morphologies or aggregation states, such as spheres, films, and fibers have been prepared to fulfil the need for various applications. Electrospinning offers a simple and straightforward way for generating ultrafine fibers with diameter in the range of nanometres to micrometres from a variety of materials. In recent decades, electrospinning has been introduced to prepare molecular sieve fibers. In this review, fibrous molecular sieves including zeolite fibers, siliceous and nonsiliceous mesoporous fibers prepared by electrospinning are summarized, and their prominent applications in optics, adsorptions, catalysis, etc. are highlighted. © 2011 The Royal Society of Chemistry.

Zhao J.-X.,Jilin University | Ding Y.-H.,Harbin Normal University
Diamond and Related Materials | Year: 2010

The unsatisfactory stability of CNT under high temperature or subject to strong oxidants has limited the potential use of p- and n-type field-effect transistors (FETs). Promisingly, boron nitride (BN) nanotubes are known to have the excellent resistance to oxidant and thermal stability at high temperature as well as the uniform electronic properties, which rends their possible application as alternative FET device. In this paper, through the theoretical computation of the noncovalent functionalization of BN nanotube by various aromatic molecules (including C10H8, C14H 10, porphyrin, DDQ, and TCNQ molecules), we for the first time evaluate its possibility as a candidate of stable FET device. We find that: (i) these aromatic molecules can be stably adsorbed on the studied BN with the adsorption energy ranging from - 0.22 (C10H8) to - 0.42 eV (porphyrin); (ii) the adsorption of electrophilic molecules on the outer sidewall of BN nanotube realizes a p-type semiconductor with a smaller band gap (~ 0.90 eV); (iii) exoherdral adsorption of nucleophilic aromatic molecules leads to an n-type semiconductor. This novel BN nanotube-based material offers great promise for molecule electronics in terms of their good stability. © 2010 Elsevier B.V. All rights reserved.

Meng L.,Jilin University | Zheng Y.,Jilin University | Hui R.,Peking Union Medical College
Hypertension Research | Year: 2013

To assess whether habitual sleep duration or insomnia increase the incidence of hypertension. PubMed, EMBASE and Cochrane were searched without language restriction. Prospective cohort studies of adults with at least a 1-year follow-up duration were included. Habitual sleep duration or symptoms of insomnia were assessed as baseline exposure, and the outcome was incidence of hypertension. Subgroup, meta-regression and sensitivity analyses were conducted to assess heterogeneity, and Egger's test was used to assess publication bias. Eleven studies (17 cohorts) were included. Short sleep duration, sleep continuity disturbance (SCD), early-morning awakening (EMA) and combined symptoms of insomnia increased the risk of hypertension incidence (the relative risks (95% confidence intervals) were 1.21 (1.05-1.40) for short sleep duration, 1.20 (1.06-1.36) for SCD, 1.14 (1.07-1.20) for EMA and 1.05 (1.01-1.08) for combined insomnia symptoms). Less evidence exists to support conclusions about the association between long sleep duration or difficulty falling asleep (DFA) and hypertension incidence. No obvious heterogeneity or publication biases were found. Our meta-analysis demonstrates that short sleep duration and single/combined symptoms of insomnia (except DFA) are associated with an increased risk of hypertension incidence. It is important to consider sleep duration and insomnia during hypertension prevention and treatment. More laboratory studies on potential mechanisms and prospective observational studies with objective measures of sleep are needed. © 2013 The Japanese Society of Hypertension. All rights reserved.

Zou X.,Jilin University | Zhang Y.,Beihang University
Chemical Society Reviews | Year: 2015

Sustainable hydrogen production is an essential prerequisite of a future hydrogen economy. Water electrolysis driven by renewable resource-derived electricity and direct solar-to-hydrogen conversion based on photochemical and photoelectrochemical water splitting are promising pathways for sustainable hydrogen production. All these techniques require, among many things, highly active noble metal-free hydrogen evolution catalysts to make the water splitting process more energy-efficient and economical. In this review, we highlight the recent research efforts toward the synthesis of noble metal-free electrocatalysts, especially at the nanoscale, and their catalytic properties for the hydrogen evolution reaction (HER). We review several important kinds of heterogeneous non-precious metal electrocatalysts, including metal sulfides, metal selenides, metal carbides, metal nitrides, metal phosphides, and heteroatom-doped nanocarbons. In the discussion, emphasis is given to the synthetic methods of these HER electrocatalysts, the strategies of performance improvement, and the structure/composition-catalytic activity relationship. We also summarize some important examples showing that non-Pt HER electrocatalysts could serve as efficient cocatalysts for promoting direct solar-to-hydrogen conversion in both photochemical and photoelectrochemical water splitting systems, when combined with suitable semiconductor photocatalysts. This journal is © The Royal Society of Chemistry.

Shao Y.-H.,Zhejiang University of Technology | Wang Z.,Jilin University | Chen W.-J.,Zhejiang University of Technology | Deng N.-Y.,China Agricultural University
Applied Intelligence | Year: 2013

In this paper, we propose a novel least squares twin parametric-margin support vector machine (TPMSVM) for binary classification, called LSTPMSVM for short. LSTPMSVM attempts to solve two modified primal problems of TPMSVM, instead of two dual problems usually solved. The solution of the two modified primal problems reduces to solving just two systems of linear equations as opposed to solving two quadratic programming problems along with two systems of linear equations in TPMSVM, which leads to extremely simple and fast algorithm. Classification using nonlinear kernel with reduced technique also leads to systems of linear equations. Therefore our LSTPMSVM is able to solve large datasets accurately without any external optimizers. Further, a particle swarm optimization (PSO) algorithm is introduced to do the parameter selection. Our experiments on synthetic as well as on several benchmark data sets indicate that our LSTPMSVM has comparable classification accuracy to that of TPMSVM but with remarkably less computational time. © 2013 Springer Science+Business Media New York.

Shao Y.-H.,Zhejiang University of Technology | Deng N.-Y.,China Agricultural University | Yang Z.-M.,Zhejiang University of Technology | Chen W.-J.,Zhejiang University of Technology | Wang Z.,Jilin University
Knowledge-Based Systems | Year: 2012

In many cases, the output of a classifier should be a calibrated posterior probability to enable post-processing. However, twin support vector machines (TWSVM) do not provide such probabilities. In this paper, we propose a TWSVM probability model, called PTWSVM, to estimate the posterior probability. Note that our model is quite different from the SVM probability model because of the different mechanism of TWSVM and SVM. In fact, for TWSVM, we first define a new ranking continues output by comparing the distances between the sample and the two non-parallel hyperplanes, and then map this ranking continues output into probability by training the parameters of an additional sigmoid function. Our PTWSVM has been tested on both artificial datasets and several data-mining-style datasets, and the numerical experiments indicate that PTWSVM yields nice results. © 2012 Elsevier B.V. All rights reserved.

Wen Q.,Jilin University | Di J.,Jilin University | Jiang L.,Beihang University | Yu J.,Jilin University | Xu R.,Jilin University
Chemical Science | Year: 2013

Oil-water separations are helping with urgent issues due to increasing industrial oily wastewater, as well as frequent oil spill accidents. Membrane-based materials with special wettability are desired to separate oils from water. However, fabrication of energy-efficient and stable membranes that are suitable for practical oil-water separation remains challenging. Zeolite films have attracted intense research interest due to their unique pore character, excellent chemical, thermal and mechanical stability, etc. Here we first demonstrate zeolite-coated mesh films for gravity-driven oil-water separation. High separation efficiency of various oils can be achieved based on the excellent superhydrophilicity and underwater superoleophobicity of the zeolite surface. Flux and intrusion pressure are tunable by simply changing the pore size, dependent on the crystallization time of the zeolite crystals, of the zeolite meshes. More importantly, such films are corrosion-resistant in the presence of corrosive media, which gives them promise as candidates in practical applications of oil-water separation. © The Royal Society of Chemistry 2013.

Wen Q.,Jilin University | Di J.,Jilin University | Zhao Y.,Beihang University | Wang Y.,Jilin University | And 2 more authors.
Chemical Science | Year: 2013

Organic molecule pollution in industrial and agricultural sewage is a serious threat to the environment and human health. Adsorption membranes have proven to be good candidates for removing contaminations from wastewater efficiently and continuously. Inorganic porous materials possessing large surface area, and high chemical and thermal stability are excellent adsorbents for organic contaminants. However, a major shortfall of the inorganic porous membranes is that they are usually fragile. Here we demonstrate flexible SiO2-TiO2 composite porous nanofibrous membranes fabricated via electrospinning technique for efficient water purification. The composite membranes exhibit high adsorption capacity and permeability in the purification test with methylene blue solution based on their hierarchical porous structure and ultrafast wettability, and can be easily recycled by calcination. Such properties, integrated with the membrane fabrication process that is energy-efficient, low cost and easy to scale-up, will facilitate their practical application in the removal of organic pollutants. This journal is © 2013 The Royal Society of Chemistry.

Gu H.,Harbin Institute of Technology | Bi L.,Jilin University | Fu Y.,Harbin Institute of Technology | Wang N.,Harbin Institute of Technology | And 2 more authors.
Chemical Science | Year: 2013

Reversibly fluorescent switchable materials have important applications in the fields of ultrahigh-density optical data storage, molecular switches, logic gates, molecular wires, optical/electronic devices, sensors, bioimaging and so on. Some systems have been developed based on smart luminescent polymers and organic photoswitchable molecules. However, the use of such materials for practical applications is dramatically restricted by their intrinsic drawbacks such as low ON/OFF ratios, irreversibility and poor environmental resistance. An imperative challenge toward real applications is to design and fabricate photoluminescence switching devices with high on/off contrast and fast response time, and especially to obtain multicolored systems, in which the photoluminescence wavelength can be easily tuned in the visible region. Here we report the first inorganic example of a multicolored photoluminescence switching system by controlling the organization of crown-type polyoxometalates (POMs) and CdSe@CdS core-shell quantum dots (QDs) into the layer-by-layer (LBL) nanostructures. The photoluminescence of this system can be switched on and off reversibly upon application of step potentials for different redox states, owing to the energy transfer between reduced POMs and QDs. This system displays a quick response (off 17 s, on 38 s), high on/off contrast (∼91%), good cycling performance (the modulation ratio is only decreased by 19% after 200 cycles) and also has the advantage of low power consumption. Furthermore, reversible four-state fluorescence switching is realized by integrating different-sized QDs in one multifunctional system. This journal is © 2013 The Royal Society of Chemistry.

Lu S.,Jilin University | Lu S.,Beijing Computational Science Research Center | Wang Y.,Jilin University | Liu H.,Jilin University | And 3 more authors.
Nature Communications | Year: 2014

Surfaces of semiconductors are crucially important for electronics, especially when the devices are reduced to the nanoscale. However, surface structures are often elusive, impeding greatly the engineering of devices. Here we develop an efficient method that can automatically explore the surface structures using structure swarm intelligence. Its application to a simple diamond (100) surface reveals an unexpected surface reconstruction featuring self-assembled carbon nanotubes arrays. Such a surface is energetically competitive with the known dimer structure under normal conditions, but it becomes more favourable under a small compressive strain or at high temperatures. The intriguing covalent bonding between neighbouring tubes creates a unique feature of carrier kinetics (that is, one dimensionality of hole states, while two dimensionality of electron states) that could lead to novel design of superior electronics. Our findings highlight that the surface plays vital roles in the fabrication of nanodevices by being a functional part of them. © 2014 Macmillan Publishers Limited.

News Article | December 9, 2015

Understanding and tailoring materials’ properties usually requires trial and error, and a bit of luck. But, as a special issue of Computational Materials Science [112, Part B, 405-546, Computational Materials Science in China.] shows, the latest generation of computation techniques and new algorithms can now model novel materials and explore existing ones better than ever before. China is embracing these new possibilities, making fast progress over the last decade as access to computation resources has become more widespread, according to Xingao Gong of Fudan University. The university is home to a Key Laboratory for Computational Physical Sciences, which has over the last five years successfully used computational tools to clarify long-held misunderstandings about the structure and properties of quaternary semiconductors tagged for future solar cells. “The profile of computational materials science as a discipline has been rising quickly in China over the last few years,” adds Editor-in-Chief, Professor Susan Sinnott of The Pennsylvania State University. “So this is an ideal time to highlight some of the best work in the field that is being carried out there.” Exploring the electronic and magnetic properties of materials theoretically begins with a simple model. By considering a few tens or hundreds of atoms at a time, computational methods can calculate properties that are scalable to larger dimensions. These basic models can be finely tuned to improve accuracy. At the University of Science and Technology of China, for example, Lixin He and colleagues are using atomic orbitals as the basic unit for ab initio electronic structure calculations of silicon, group IV and III-V semiconductors including technologically important GaAs and GaN, as well as alkali and 3d transition metals. Focusing on orbital physics can be a helpful tactic in unpicking the novel electronic and magnetic behavior of transition metal oxides, which are a platform for many functional devices, according to Hua Wu at Fudan University. The combination of charge, spin, and orbital degrees of freedom in these materials leads to unusual – and useful – effects such as colossal magnetoresistance and multiferroicity. First principles calculations based on density functional theory (DFT), where quantum mechanical equations determine the density of electrons, are proving effective and versatile in understanding the new generation of planar materials, such as graphene, silicene, and boron nitride. Despite being well known for decades, DFT has been refined in recent years so it can now be used to tailor the physical properties of 2D materials for applications. DFT can also help unravel the science behind exotic materials like topological insulators, which have an insulating core but surface conducting electrons. Researchers at Beijing Institute of Technology are using this approach to explore such fantastic phenomena as these in solid materials that would be difficult to comprehend by other means. Likewise, modeling is effective when it comes to identifying and assessing materials for extreme environments. A group at Beihang University is using DFT to identify materials able to withstand the extreme temperatures and irradiation levels inside thermonuclear reactors. Taking a different approach to models, meanwhile, can yield new insights. A group at Jilin University, for example, has devised a computational method based on a ‘swarm intelligence’ algorithm inspired by natural systems such as ant colonies, bee swarms, and flocks of birds. The self-improving approach works particularly well with atomic and molecular clusters, nanoparticles, and 3D bulk materials. “I am very excited to see that young scientists in China now have a strong interest in developing new algorithms and first principles approaches based on local atomic orbitals,” says Gong. The rise of computational methods to understand materials behaviors and properties, and drive new materials’ discovery, has been particularly impressive in China, agrees Baptiste Gault, senior publisher at Elsevier. “It is very timely to provide an overview of the state-of-the-art here and Computational Materials Science is the preeminent forum.” This special issue is published in Computational Materials Science- 112, Part B, 405-546 "Computational Materials Science in China". To find out more about each article included within this special issue, please follow the below links: The novel electronic and magnetic properties in 5d transition metal oxides system First-principles investigations on the Berry phase effect in spin–orbit coupling materials Recent progresses in real-time local-basis implementation of time dependent density functional theory for electron–nucleus dynamics Modeling and simulation of helium behavior in tungsten: A first-principles investigation Recent advances in computational studies of organometallic sheets: Magnetism, adsorption and catalysis Tailoring physical properties of graphene: Effects of hydrogenation, oxidation, and grain boundaries by atomistic simulations

HONG KONG, Dec. 28, 2016 /PRNewswire/ -- Jebsen Group (Jebsen), a regional leader in marketing and distribution of premium products across Greater China, has recently released its Corporate Social Responsibility (CSR) Report 2016, which marks the 8th consecutive year that Jebsen has published its annual CSR report since 2009. It summarises Jebsen's innovative and effective practices in CSR management, business partnerships, environmental conservation, staff well-being, and philanthropy in 2015 across its diverse business units. With clearly established objectives and the Group's strong commitment in CSR, the programmes have taken economic, social and environmental considerations into the company's strategic development and operations. Jebsen's business growth has been successfully achieved, while expanding its efforts in various aspects of CSR from environment conservation, staff well-being to philanthropy. With a strong focus on the betterment of society, Jebsen's invested HKD 4.5 million in CSR activities in 2015. A total of 62 philanthropic activities were organised, garnering a total attendance of 898 people/times and raising HKD 250,000 in funds. By the end of 2015, Project Morning Star, a philanthropic initiative launched by Jebsen in partnership with ORBIS in 2011, has benefited over 1.2 million ophthalmic patients in rural China in its first five-year plan thanks to donations of over RMB 5.15 million made by the Group. Due to the tremendous achievements and impact over the first five years of this programme, the next five-year plan was launched in October 2016. More than a million people are expected to benefit from it, with Jebsen donating RMB 7.4 million between 2016 and 2020. Apart from Project Morning Star, Jebsen's commitment to caring for the underprivileged is also reflected in its Life is Art programme. Launched in 2014 in Hong Kong, Shanghai, Beijing and Guangzhou, this innovative programme focuses on caring for children with autism and children from migrant families, with the Shutterbug Club, Art Jamming Class and Djembe Drum Class as some of its major activities. Through the workshops, outdoor photographic exploration, DIY album creation and mini galleries, the Shutterbug Club provides the children with the opportunity to observe the world through a different lens and learn about colour and beauty. On the other hand, by organising Djembe Drum Class, teaching music and rhythm to the autistic children and providing them the opportunity to perform at music concerts and at Jebsen's annual dinner party, the programme harnesses their creativity and increases their confidence through music. In the second half of 2015, more than 80 Jebsen employees participated in these programmes to show their love for the children. Jebsen has also continued its support to education in order to cultivate the creativity, commitment and potential of students in universities. Jebsen will donate RMB 1 million in total over 5 years, from 2015 till 2019, to Nankai University for the second phase of the Nankai- Jebsen Education Fund, awarding outstanding students and teachers achieving excellent performance. Jebsen Group also cooperated with Jilin University in 2015, marking the third year of a partnership that seeks to nurture future business leaders through the means of a summer internship programme and insightful lectures. In Hong Kong, the Jebsen Educational Foundation Scholarship has supported more than 400 students over the past 20 years at The Hong Kong University of Science and Technology. Jebsen considers the well-being of its staff to be a key priority, and recognises employees to be one of its most valuable assets. Driven by its Employer Value Proposition (EVP) - "Success Breeds Success", the Group enhanced the communication with staff by launching "Jebsen Heroes" to highlight the staff's success stories within the Group and share their achievements. In terms of staff development, the Group has developed a Career Pathing Framework and continued training programmes to support employees in their career development. In 2016, Jebsen invested HKD 3.5 million in staff training, and the total training productivity was 2,130 person-times or 14,732 hours. Advocating a positive work and life attitude, the Group organised a series of staff engagement activities to foster happier minds and healthier bodies, such as wellness seminars and exercises to guide employees to maintain their physical and mental wellness. Environmental conservation is another core area of Jebsen's CSR endeavours as it aims to strengthen sustainable development. In 2015, emissions of the Jebsen Group totalled 8,772.85 tonnes of CO2-e, with carbon intensity having decreased by 10% compared to the 2009 baseline level. Meanwhile, Jebsen continues to invest in two climate friendly projects, and purchased 7207.74 tonnes of carbon credit to achieved carbon neutrality for three years in a row. To promote green and healthy living, Jebsen offers consumers a variety of green products and services including home and building products, water purifiers, etc. Internally, Jebsen launched the "Green Office Solution", encouraging staff to reduce printing, using recyclable paper, saving water and electricity. As a Diamond Member of WWF Corporate Membership Program (CMP) in Hong Kong since 2000, Jebsen proudly participated in the Earth Hour event for the eighth consecutive year, when all non-essential lights, neon signs, billboards and computers at Jebsen locations across the region were turned off for an hour during the global event. As a company deeply rooted in the Greater China region for the past 120 years, Jebsen has been awarded seven corporate social responsibility awards in 2015 which recognise its continuous active initiatives in philanthropy, staff well-being and environment conservation. "Grounded by its core values of Commitment, Excellence, Responsibility, Recognition, and Trust, Jebsen will expand its efforts in contributing to the communities and sustain innovation and adaptiveness to market changes," said Mr Helmuth Hennig, Group Managing Director of Jebsen. For more details, please click below links to download Jebsen CSR Report 2016. Founded in 1895, Jebsen Group is a focused marketing and distribution organisation. With a long, unique established presence and deep understanding of Mainland China, Hong Kong, Macau and Taiwan, the Jebsen Group is committed to supporting our partners' needs in building market demand, generating and supporting sales, and serving as an important link to customers throughout the region.  With a broad spectrum of consumer, beverage, industrial, and motors products, Jebsen offers some 200 of the world's leading products extensive local market access with a high degree of specialisation. Outside the region, the Jebsen Group enjoys close ties with sister companies in Australia, South East Asia, Denmark, Germany, Middle East and the United States. For more information, visit and Jebsen Facebook page (, or follow us on Sina Weibo (, WeChat (id: jebsen1895) and LinkedIn (id: jebsen group).

Fei T.,Jilin University | Jiang K.,Jilin University | Liu S.,Jilin University | Zhang T.,Jilin University
Sensors and Actuators, B: Chemical | Year: 2014

Nanoporous polymer based on divinylbenzene was synthesized by radical polymerization with a solvothermal route. The nanoporous characteristic of the resultant polymer poly(divinylbenzene) (PDVB) was determined by a series of characterizations. The hydrophobic porous polymer was used as the host to prepare composited humidity sensitive materials. Different levels of LiCl were loaded into the nanoporous polymer and their humidity sensing properties were researched. Humidity sensitivities of the composites were greatly improved by LiCl loading compared with pure PDVB. The sensor based on 5 wt% LiCl/PDVB showed the best sensing properties to relative humidity (RH). The impedance of the optimum sensor changed three orders of magnitude over the whole humidity range, with a good linearity and rapid response. The mechanism by the complex impedance plots suggests the protons are the domination carrier in low humidities and ions (Li+ and Cl-) in a high humidity range. The results demonstrate nanoporous polymers are a new kind of promising materials for humidity sensors. © 2013 Elsevier B.V. All rights reserved.

Zhang Y.,Jilin University | Sun J.,Jilin University
ACS Nano | Year: 2015

In this study, we demonstrate multilevel and multicomponent layer-by-layer (LbL) assembly as a convenient and generally applicable method for the fabrication of nanofibrillar films by exploiting the dynamic nature of polymeric complexes. The alternate deposition of poly(allylamine hydrochloride)-methyl red (PAH-MR) complexes with poly(acrylic acid) (PAA) produces nanofibrillar PAH-MR/PAA films, which involves the disassembly of PAH-MR complexes, the subsequent assembly of PAH with PAA, and the PAA-induced assembly of MR molecules into MR nanofibrils via a π-π stacking interaction. The aqueous solution of weak polyelectrolyte PAA with a low solution pH plays an important role in fabricating nanofibrillar PAH-MR/PAA films because proton transfer from acidic PAA to MR molecules induces the formation of MR nanofibrils. The generality of the multilevel and multicomponent LbL assembly is verified by alternate assembly of complexes of 1-pyrenylbutyric acid (PYA) and PAH with PAA to fabricate PAH-PYA/PAA films with organized nanofibrillar structures. Unlike the traditional static LbL assembly, the multilevel and multicomponent LbL assembly is dynamic and more flexible and powerful in controlling the interfacial assembly process and in fabricating composite films with sophisticated structures. These characteristics of multilevel and multicomponent LbL assembly will enrich the functionalities of the LbL-assembled films. © 2015 American Chemical Society.

Su X.,Jilin University | Xu W.,Jilin University | Du S.,Jilin University
Journal of Water Supply: Research and Technology - AQUA | Year: 2014

Artificial recharge is becoming one of the most important ways to deal with water shortage and induced environmental geological problems, but it also brings potential groundwater contaminant risks, especially under extreme weather conditions. A classic method, DRASTIC, and groundwater flow simulation model have been used to analyze the response of groundwater vulnerability to artificial recharge under extreme weather conditions. The results show that a simultaneously abundant year and scarce year of the local area and the Han River Basin are 7.46 and 6.60%, respectively. The quantities of artificial recharge water would be 8.72 × 104 m3/a and 4.64 × 104 m3/a, respectively. Five scenarios with extreme weather conditions were discussed. The groundwater vulnerability would not change a great deal without extreme conditions under artificial recharge. Under extreme abundant conditions, the induced groundwater level lowering would making the depth of groundwater level increase, and the vulnerability would be lower. Under extreme abundant conditions, the decreased depth of groundwater level and increased net recharge made the vulnerability increase obviously, and the low vulnerability area was converted into the moderate and high vulnerability areas. More attention should be paid to the quality of recharged water and monitoring schemes should be carried out around the infiltration field. © IWA Publishing 2014.

Wang L.,Jilin University | Wang K.,Jilin University | Zou B.,Jilin University | Ye K.,Jilin University | And 2 more authors.
Advanced Materials | Year: 2015

An organic crystal adopts a molecular packing that can be readily perturbed by external stresses like tensile forces, isotropic pressure, and anisotropic pressure through mechanical smashing, grinding, and compressing, respectively. As a result, the crystals display mechanoluminescence (ML) in response to different mechanical stimuli. The present study provides a model in which three distinct MLs are combined into one organic material. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Tian H.,Jilin University | Yuan R.,Chongqing University | Zhao Y.,Chongqing University
Dianwang Jishu/Power System Technology | Year: 2013

To improve the reliability evaluation efficiency of distribution network containing distributed generation (DG), a network partition-based fault recovery strategy is proposed. Considering the influence of DG on distribution network reliability, a probability distribution model for the reliability of distribution network containing DG and corresponding algorithm are put forward, thus the defect of traditional expectation indices that measure system risk only in the meaning of probabilistic mean values is remedied. Based on the thinking of partitioning of distribution network, the reliability indices of distribution network are characterized by random function in system level and nodal hierarchies, and combining with non-parametric kernel density estimation the probability distribution calculation of random function expression for reliability indices is implemented. Simulation results of RBTS-BUS6 system show that the proposed method is effective.

Zhao Y.,Jilin University | Zhao Y.,New York State Institute for Basic Research in Developmental Disabilities | Gong C.-X.,New York State Institute for Basic Research in Developmental Disabilities
Cellular and Molecular Neurobiology | Year: 2014

Chronic cerebral hypoperfusion (CCH) is a common consequence of various cerebral vascular disorders and hemodynamic and blood changes. Recent studies have revealed an important role of CCH in neurodegeneration and dementia, including vascular dementia and Alzheimer’s disease (AD). This article reviews the recent advances in understanding CCH-induced neurodegeneration and AD-related brain pathology and cognitive impairment. We discuss the causes and assessment of CCH, the possible mechanisms by which CCH promotes Alzheimer-like pathology and neurodegeneration, and animal models of CCH. It appears that CCH promotes neurodegeneration and AD through multiple mechanisms, including induction of oxidative stress, Aβ accumulation and aggravation, tau hyperphosphorylation, synaptic dysfunction, neuronal loss, white matter lesion, and neuroinflammation. Better understanding of the mechanisms of CCH will help develop therapeutic strategies for preventing and treating neurodegeneration, including sporadic AD and vascular dementia, caused by CCH. © 2014, Springer Science+Business Media New York.

Zheng J.H.,Jilin University | Jiang Q.,Jilin University | Lian J.S.,Jilin University
Applied Surface Science | Year: 2011

Flower-like ZnO nanorods have been synthesized by heating a mixture of ZnO/graphite powders using the thermal evaporation and vapor transport on Si (1 0 0) substrates without any catalyst. The structures, morphologies and optical properties of the products were characterized in detail by using X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), photoluminescence (PL) and Raman spectroscopy. The synthesized products consisted of large quantities of flower-like ZnO nanostructures in the form of uniform nanorods. The flower-like ZnO nanorods had high purity and well crystallized wurtzite structure, whose high crystalline quality was proved by Raman spectroscopy. The as-synthesized flower-like ZnO nanorods showed a strong ultraviolet emission at 386 nm and a weak and broad yellow-green emission in visible spectrum in its room temperature photoluminescence (PL) spectrum. In addition, the growth mechanism of the flower-like ZnO nanorods was discussed based on the reaction conditions. © 2010 Elsevier B.V. All rights reserved.

Sun H.,Jilin University
Lecture Notes in Electrical Engineering | Year: 2016

The rapid development of science and technology makes the mouse become the most commonly used product life and work, but also the most frequent computer equipment, so users gradually the use of mouse proposed more requirements, including comfortable operation, flexible moving and accurate positioning, operation comfort discomfort the most attention. The fatigue caused by long time and high frequency use of mouse is known as the mouse hand. The disease has exerted adverse effect on people’s life and work. In the paper, based on the experimental data of fatigue of using mouse, in-depth analysis was conducted on the bone and meridian of the arm using traditional mouse as well as the wrist force. On the basis of the man–machine factors, the traditional mouse was improved in the design. Besides, the optimization scheme that could reflect mouse comfort and effectively avoid mouse hand was put forward. © Springer Science+Business Media Singapore 2016.

A poly(butyl methacrylate-co-ethyleneglyceldimethacrylate) (poly(BMA-EDMA)) monolithic column was prepared with in situ polymerization method and modified with allylamine-β-cyclodextrin (ALA-β-CD) and nano-cuprous oxide (Cu2O). A polymer monolith microextraction method was developed with the modified monolithic column for the preconcentration of polychlorinated biphenyls combined with gas chromatography-electron capture detector. Various parameters affecting the extraction efficiency were investigated and optimized. Under the optimum experimental conditions, we obtained acceptable linearities, low limits of detection, and good intra-day/inter-day relative standard deviations. Because of the hydrophobic properties of β-CD and the porous nano structure of Cu2O, the enrichment capacity of the poly(BMA-EDMA) monolithic column was significantly improved. The extraction efficiency followed the order: poly(BMA-EDMA-ALA-β-CD-Cu2O)>poly(BMA-EDMA-ALA-β-CD)>poly(BMA-EDMA)>direct GC analysis. When applied to the determination of polychlorinated biphenyls in wine samples, low limits of detection (0.09ngmL-1) were obtained under the preoptimized conditions (sample volume 1.0mL, sample flow rate 0.1mLmin-1, eluent volume 0.1mL, and eluent flow rate 0.05mLmin-1). In addition, the present method was employed to determine polychlorinated biphenyls in red wine samples and the accuracy was assessed through recovery experiments. The obtained recovery values were in the range of 78.8-104.1% with relative standard deviations less than 9.0%. © 2014 Elsevier B.V.

Bai Z.K.,Jilin University
Journal of molecular histology | Year: 2013

The aim of this study was to investigate the differential expression and regulation of Runt-related transcription factor 3 (Runx3) in mouse uterus during early pregnancy and its regulation by steroid hormones using in situ hybridization. There was a low level of the Runx3 mRNA expression in the mouse uterus on days 1-4 of pregnancy. On day 5 when embryo implanted, Runx3 mRNA signal was obviously observed in the stromal cells surrounding the implanting blastocyst. From day 6 to 8 of pregnancy, Runx3 mRNA was highly expressed in the decidual cells and mesometrial decidual beds. Similarly, Runx3 mRNA was strongly expressed in decidualized cells under artificial decidualization. Compared with the delayed uterus, a high level of Runx3 mRNA signal was detected in the uterus with activated implantation. In the ovariectomized mouse uterus, estrogen could induce the expression of Runx3, while progesterone had no effects. These results suggest that Runx3 may play an important role during mouse implantation and decidualization. Estrogen can induce the expression of Runx3 in the ovariectomized mouse uterus.

Lin L.,Dalian Polytechnic University | Zhai S.-R.,Dalian Polytechnic University | Xiao Z.-Y.,Dalian Polytechnic University | Song Y.,Dalian Polytechnic University | And 2 more authors.
Bioresource Technology | Year: 2013

In continuation of previous work on utilizing rice husks, this study aimed to prepare mesoporous activated carbons using residues of sodium hydroxide-pretreated RHs, and then examine their dye adsorption performance. The influences of the activation temperature and activation time on the surface area, pore volume, and pore radius of the activated carbon were investigated based on nitrogen adsorption/desorption isotherms and transmission electron microscopy. The adsorptive behavior of the mesoporous activated carbons obtained under optimum preparation conditions was evaluated using methyleneblue as the model adsorbate. The adsorption kinetics was studied by pseudo-first-and pseudo-second-order models, and the adsorption isotherms were studied by Langmuir and Freundlich models. The pseudo-second-order model and Langmuir isotherm were found to fit well the adsorption characteristics of the as-prepared mesoporous activated carbons. Thermodynamic data of the adsorption process were also obtained to elucidate the adsorption thermo-chemistry between the activated carbons produced from NaOH-pretreated RHs and MB molecules. © 2013 Elsevier Ltd.

Zhang F.,Jilin University | Zou X.,Jilin University | Gao X.,Jilin University | Fan S.,Jilin University | And 3 more authors.
Advanced Functional Materials | Year: 2012

Hydrogen-based energy is a promising renewable and clean resource. Thus, hydrogen selective microporous membranes with high performance and high stability are demanded. Novel NH 2-MIL-53(Al) membranes are evaluated for hydrogen separation for this goal. Continuous NH 2-MIL-53(Al) membranes have been prepared successfully on macroporous glass frit discs assisted with colloidal seeds. The gas sorption ability of NH 2-MIL-53(Al) materials is studied by gas adsorption measurement. The isosteric heats of adsorption in a sequence of CO 2 > N 2 > CH 4 -H 2 indicates different interactions between NH 2-MIL-53(Al) framework and these gases. As-prepared membranes are measured by single and binary gas permeation at different temperatures. The results of singe gas permeation show a decreasing permeance in an order of H 2 > CH 4 > N 2 > CO 2, suggesting that the diffusion and adsorption properties make significant contributions in the gas permeation through the membrane. In binary gas permeation, the NH 2-MIL-53(Al) membrane shows high selectivity for H 2 with separation factors of 20.7, 23.9 and 30.9 at room temperature (288 K) for H 2 over CH 4, N 2 and CO 2, respectively. In comparison to single gas permeation, a slightly higher separation factor is obtained due to the competitive adsorption effect between the gases in the porous MOF membrane. Additionally, the NH 2-MIL-53(Al) membrane exhibits very high permeance for H 2 in the mixtures separation (above 1.5 × 10 -6 mol m -2 s -1 Pa -1) due to its large cavity, resulting in a very high separation power. The details of the temperature effect on the permeances of H 2 over other gases are investigated from 288 to 353 K. The supported NH 2-MIL-53(Al) membranes with high hydrogen separation power possess high stability, resistance to cracking, temperature cycling and show high reproducibility, necessary for the potential application to hydrogen recycling. Continuous NH 2-MIL-53(Al) metal-organic framework (MOF) membranes are prepared successfully on macroporous glass frit discs assisted with colloidal seeds to be evaluated for hydrogen gas separation. As-prepared membrane is studied by single and binary gas permeation of H 2, CH 4, N 2 and CO 2 at different temperatures. The supported NH 2-MIL-53(Al) membranes exhibit high permeance and high selectivity, which result in a very high separation power. The robust membranes with high performance are expected in potential applications for hydrogen recycling. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Chan J.G.Y.,University of Sydney | Bai X.,Jilin University | Traini D.,University of Sydney
Expert Opinion on Drug Delivery | Year: 2014

Introduction: Tuberculosis (TB) remains rampant throughout the world, in large part due to the lengthy treatment times of current therapeutic options. Rifapentine, a rifamycin antibiotic, is currently approved for intermittent dosing in the treatment of TB. Recent animal studies have shown that more frequent administration of rifapentine could shorten treatment times, for both latent and active TB infection. However, these results were not replicated in a subsequent human clinical trial. Areas covered: This review analyses the evidence for more frequent administration of rifapentine and the reasons for the apparent lack of efficacy in shortening treatment times in human patients. Inhaled delivery is discussed as a potential option to achieve the therapeutic effect of rifapentine by overcoming the barriers associated with oral administration of this drug. Avenues for developing an inhalable form of rifapentine are also presented. Expert opinion: Rifapentine is a promising active pharmaceutical ingredient with potential to accelerate treatment of TB if delivered by inhaled administration. Progression of current fundamental work on inhaled anti-tubercular therapies to human clinical trials is essential for determining their role in future treatment regimens. While the ultimate goal for global TB control is a vaccine, a short and effective treatment option is equally crucial. © 2014 Informa UK, Ltd.

Xue S.,Jilin University | Yao L.,Jilin University | Shen F.,Jilin University | Gu C.,Jilin University | And 2 more authors.
Advanced Functional Materials | Year: 2012

Highly efficient and fully solution-processed white organic light-emitting diodes (WOLEDs) based on fluorescent small molecules and a polar conjugated polymer as electron-injection material are reported. The emitting layer in the WOLEDs is a blend of new blue-, green-, and red-fluorescent small molecules, with a blending ratio of 100:0.4:0.8 (B/G/R) by weight, and a methanol/water soluble conjugated polymerpoly[(9,9-bis(30-(N,N-dimethylamino)propyl)-2,7- fluorene)-alt-2,7-(9,9-dioctylfluorene)] (PFN) acts as the electron-injection layer (EIL). All the organic layers are spin-coated from solution. The device exhibits pure white emission with a maximum luminous efficiency of 9.2 cd A -1 and Commission Internationale d'Eclairage Coordinates of (0.35, 0.36). PFN acting as the EIL material plays a key role in the improvement of the device performance when used in solution-processed small-molecule WOLEDs. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Liu S.,Jilin University | Na W.,Jilin University | Pang S.,Jilin University | Su X.,Jilin University
Biosensors and Bioelectronics | Year: 2014

In this paper, we have developed a simple and rapid method for the detection of Pb2+ based on the DNA sequence capped CdS quantum dots (QDs). We utilized the designed guanine (G)-rich DNA sequence (PS2.M) as a coating reagent to synthesize the DNA-capped CdS QDs. The designed G-rich DNA sequence PS2.M can bind with hemin to form G-quadruplex/hemin complex with K+, accompanied by the fluorescence quenching of CdS QDs via the photoinduced electron transfer. Pb2+ can induce conformational changes in the G-quadruplex/hemin complex to release the hemin molecules, so the quenched fluorescence of CdS QDs could be recovered. Therefore, the new fluorescent analysis system could be applied for the detection of Pb2+ based on the label-free DNA sequence capped CdS QDs. © 2014 Elsevier B.V.

Zhang H.,Jilin University | Zhang H.,Karolinska University Hospital | Wu L.-M.,Jilin University | Wu J.,Jilin University
Mediators of Inflammation | Year: 2011

Apolipoprotein E (apoE) is a multifunctional glycosylated protein characterized by its wide tissue distribution. Despite its importance in lipid transport and atherosclerosis pathogenesis, apoE is associated with neurodegenerative disorders such as Alzheimer's disease (AD) and Parkinson disease, and autoimmune disorders such as multiple sclerosis and psoriasis. Among others, the role of apoE in modulating inflammation and oxidation is crucial in elucidating the risk factors of the above diseases since the function of apoE is closely linked with both proinflammatory and antiinflammatory cytokines. Moreover, apoE modulates inflammatory and immune responses in an isoform-dependent manner. Correspondingly, inflammatory cytokines can either upregulate or downregulate the production of apoE in various tissue types. However, studies on the interactions between apoE and cytokines occasionally yield conflicting results, highlighting the complex roles of apoE and cytokines in various disorders. The present paper summarizes the current knowledge about the cross-talk between apoE and cytokines, with emphasis on the effects of apoE on the Th1/Th2 balance. Copyright © 2011 Hongliang Zhang et al.

Sun P.D.,Jilin University
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery | Year: 2011

To study the feasibility and influence of vagus nerve preservation in radical operation for proximal gastric cancer. Thirty-two patients with early or T2 cardia cancer from May 2007 to May 2009 were enrolled and randomized into two groups, i.e. vagus nerve preservation group(n=16) and control group(n=16). Two groups were compared with regard to operative time, anastomotic fistula, digestive discomforts, body weight, survival rate, findings on gastroscope and abdominal ultrasonography. There were no statistically significant differences between the two groups in operative time (2.8 vs. 2.5 h), postoperative complications rate (25.0% vs. 31.3%). No recurrence or mortality was observed after one-year follow-up. However, patients who underwent vagus nerve preservation had less postprandial discomforts(3 vs. 12 cases), bile reflux(3 vs. 10 cases), atrophic gastritis(1 vs. 9 cases), gallstones(1 vs. 8 cases), body mass index, and diarrhea(P<0.05). For patients with early gastric cancer, preservation of the vagus nerve during radical gastrectomy results in less complications and does not compromise patient survival.

Yuan H.,Jilin University | Wang K.,Jilin University | Yang K.,CAS Shanghai Institute of Applied Physics | Liu B.,Jilin University | Zou B.,Jilin University
Journal of Physical Chemistry Letters | Year: 2014

Mechanochromic materials with aggregation-induced enhanced emission (AIEE) characteristic have been intensively expanded in the past few years. In general, intermolecular interactions invariably alter photophysical processes, while their role in the luminescence properties of these AIEE-active molecules is difficult to fully recognize because the pressurized samples possess amorphous nature in many cases. We now report the high-pressure studies on a prototype AIEE-active molecule, tetraphenylethene, using diamond anvil cell technique with associated spectroscopic measurements. An unusual pressure-dependent color, intensity, and lifetime change in tetraphenylethene has been detected by steady-state photoluminescence and time-resolved emission decay measurements. The flexible role of the aromatic C-H⋯π and C-H⋯C contacts in structural recovery, conformational modification, and emission efficiency modulation upon compression is demonstrated through structure and infrared analysis. SECTION: Spectroscopy, Photochemistry, and Excited States © 2014 American Chemical Society.

Du Y.,Jilin University
Lecture Notes in Electrical Engineering | Year: 2016

This research applies the theory of human-machine-environment system engineering, using the measurement method to analyze the relationship between the user and the various components of the office chair in the sedentary condition. The measurement and analysis of the numerical value of the Chinese office crowd, find the basic design criteria of the modern office chair, which is seat height, seat width, seat depth, seat angle, seat back, and seat armrest. The research aims at optimizing modern office chair design and combining with human-machine-environment system engineering to make the design more scientific and reasonable. © Springer Science+Business Media Singapore 2016.

Yu Y.,Jilin University | Wu B.,Jilin University | Lim C.W.,City University of Hong Kong
International Journal of Mechanical Sciences | Year: 2012

This paper analyzes the electromechanical post-buckling response of an axially stressed clamped-clamped beam actuator subjected to a symmetric electrostatic field. Numerical solutions of the nonlinear integral-differential governing equation are first obtained by constructing the extended systems and applying the shooting method. The corresponding analytical approximate solutions are then established by combining Newton linearization with Galerkins method. In contrast to the classical Galerkins method, the linearization is performed prior to its application. This yields a set of linear algebraic equations instead of nonlinear algebraic equations, and hence analytical approximate solutions are established. These analytical approximate solutions show excellent agreement with numerical solutions from the shooting method, and they are valid for a wide range of beam-center deflection. The analytical approximate method presented here is simple in principle and it is easy to be implemented with the help of any symbolic computational software. © 2012 Elsevier Ltd. All rights reserved.

Pan L.L.,Jilin University | Li G.Y.,Jilin University | Su Y.C.,Jilin University | Lian J.S.,Jilin University
Polymer Degradation and Stability | Year: 2012

Ammonium polyphosphate (APP) and triphenyl phosphate (TPP) were added in a dicyclopentadiene (DCPD) modified unsaturated polyester resin (UPR) as intumescent flame retardant (IFR) and the combustion resistance effects were investigated. Flammability and thermal stability were investigated through limiting oxygen index (LOI) test and UL-94 vertical burning test and by using thermogravimetric analysis (TGA) and differential scanning calorimeter (DSC). When 57.6 wt.% of the flame retardant was added, the LOI value increased from 20.9 to 27.2 and a V-0 rating in UL-94 test was obtained. The fire-resistant time reached to 26∼34 min. The TGA and DSC analyses showed that the char yield was increased by the introduction of APP and TPP system and decomposition of the phosphorous additives yielded strongly phosphoric acids which effectively promoted the cross-linking reaction during the burning process. So, a profound flame retardant effect was obtained as APP and TPP were added to the unsaturated polyester resin. © 2012 Elsevier Ltd. All rights reserved.

Pei Y.-C.,Jilin University
International Journal of Mechanical Sciences | Year: 2012

A rotating flexible annular micro-disk under thermoelastic coupling is modeled to investigate the thermoelastic damping in the rotating micro-disk in Microdrives. Transverse deflection of the micro-disk is considered as a function of both disk radial and circumferential coordinates, and its thermoelastic temperature increment is modeled by simultaneously involving disk thickness, radial and circumferential coordinates. Heat convection boundaries are assumed at disk top and bottom surfaces. System governing equations with the centrifugal stresses of disk rotation and thermoelastic coupling terms are discretized along disk radial direction by an annular finite element, and a quadratic eigenvalue problem is yielded to determine the thermoelastic damping. Mode shapes of the transverse deflection and temperature increment are presented, effects of disk rotation, surface convection and ambient temperature on natural frequency, frequency shift and thermoelastic damping are investigated. The maximum thermoelastic damping is obtained by optimizing disk thickness, inner radius and radial width. © 2012 Elsevier Ltd. All rights reserved.

Wu H.,Jilin University
Applied Mechanics and Materials | Year: 2013

According to inputting different combination of conditions so as to produce different impacts, software testing designs a large number of test cases. If the implementation of an overall test, due to the limit of the combination of conditions, it is difficult to carry out. In order to generate high quality test cases as early as possible to improve the efficiency of software testing, it is designed a generation tool of the automatic software testing case on orthogonal experimental design. For the test data, the use of that tool design test cases. The practice shows that a small number of test cases are generated, the error detection ability is strong, and it greatly improves the efficiency of software testing. © 2013 Trans Tech Publications Ltd, Switzerland.

Li A.,Jilin University
Faguang Xuebao/Chinese Journal of Luminescence | Year: 2012

We examine the absorption and dispersion properties of a weak probe field in a three-level lambda system closed by a microwave field. We find that, due to quantum interference in this closed-loop atomic system, the absorption and dispersion properties of a weak probe field depend on the relative phase of the applied fields. A large inversionless gain and a large index of refraction with zero absorption can be obtained by tuning the relative phase into proper values. In the case of three-photon off-resonance, the probe gain (absorption) exhibits periodically oscillatory behavior versus time.

Dai Q.Q.,Jilin University | Zhu Y.F.,Jilin University | Jiang Q.,Jilin University
Physical Chemistry Chemical Physics | Year: 2014

Grain boundaries (GBs) that inevitably appear in CVD-grown graphene affect the electronic properties of graphene-based nanomaterials. In this paper, we introduce 558 GB (composed of a pair of pentagons and one octagon alternately) into armchair graphene nanoribbons (AGNRs) and divide them into three groups in light of the end configurations of 558 GB at the ribbon edges. By using first-principles calculations, the variations of electronic and magnetic properties with two adjustable parameters W (ribbon widths) and NZ (the distances between 558 GBs) are systematically investigated for each group. The results show that different electronic and magnetic behaviors versus W and NZ are presented for varying end configurations of 558 GB, including nonmagnetic metals, ferromagnetic metals and nonmagnetic semiconductors. By introducing 558 GB into AGNRs, the impurity states that are completely contributed by 558 GB appear around the Fermi level. Furthermore, a ferromagnetic ordering on the two zigzag chains of 558 GB occurs for the ferromagnetic metals due to the spin splitting energy bands near the Fermi level. These unique electronic and magnetic properties of AGNRs with 558 GB would find their potential applications in electronic and spintronic devices. This journal is © the Partner Organisations 2014.

Gao N.,Jilin University | Li J.C.,Jilin University | Jiang Q.,Jilin University
Physical Chemistry Chemical Physics | Year: 2014

The geometric and electronic properties of silicene paired with a MoS 2 substrate are studied systematically by using density functional theory with van der Waals corrections. It is found that the nearly linear band dispersions can be preserved in the heterobilayers due to the weak interface interactions. Meanwhile, the band gap is opened because of the sublattice symmetry broken by the intrinsic interface dipole. Moreover, the band gap values could be effectively modulated under an external electric field. Therefore, a way is paved for silicene-MoS2 heterobilayers to be candidate materials for logic circuits and photonic devices. © 2014 the Partner Organisations.

Bai Y.,Jilin University | Luo Q.,Jilin University | Liu J.,Jilin University
Chemical Society Reviews | Year: 2016

Proteins, as the elemental basis of living organisms, mostly execute their biological tasks in the form of supramolecular self-assemblies with subtle architectures, dynamic interactions and versatile functionalities. Inspired by the structural harmony and functional beauty of natural protein self-assemblies to fabricate sophisticated yet highly ordered protein superstructures represents an adventure in the pursuit of nature's supreme wisdom. In this review, we focus on building protein self-assembly systems based on supramolecular strategies and classify recent progress by the types of utilized supramolecular driving forces. Especially, the design strategy, structure control and the thermodynamic/kinetic regulation of the self-assemblies, which will in turn provide insights into the natural biological self-assembly mechanism, are highlighted. In addition, recently, this research field is starting to extend its interest beyond constructing complex morphologies towards the potential applications of the self-assembly systems; several attempts to design functional protein complexes are also discussed. As such, we hope that this review will provide a panoramic sketch of the field and draw a roadmap towards the ultimate construction of advanced protein self-assemblies that even can serve as analogues of their natural counterparts. © 2016 The Royal Society of Chemistry.

Li Y.,Jilin University | Yu J.,Jilin University
Chemical Science | Year: 2016

Since the launch of the Materials Genome Initiative by the US government in 2011, many computer techniques have been developed to predict the structures and properties of advanced materials, providing important guidance for laboratory experimentation and a promising new direction for future materials innovation. However, lots of inorganic materials are difficult for computers to process because of their complex three-dimensionally extended structures. Fortunately, many of these materials are built from well-defined stacking layer modules, and the stacking sequences of their layer modules unambiguously determine their three-dimensional structures. Such one-dimensional stacking sequence representation is naturally accessible for computer processing, easing the problems not only of structure elucidation, but also in the enumeration, evaluation, and screening of a large number of unknown materials with desired properties. More importantly, with the aid of various computational methods, we may reveal the relationship between the stacking sequences and the properties of these materials, which is a key prerequisite for function-led targeted synthesis. This Minireview covers the most recent progress in this emerging area. © The Royal Society of Chemistry 2016.

Errea I.,Donostia International Physics Center | Errea I.,Ikerbasque | Calandra M.,French National Center for Scientific Research | Pickard C.J.,University College London | And 7 more authors.
Physical Review Letters | Year: 2015

We use first-principles calculations to study structural, vibrational, and superconducting properties of H2S at pressures P≥200GPa. The inclusion of zero-point energy leads to two different possible dissociations of H2S, namely 3H2S→2H3S+S and 5H2S→3H3S+HS2, where both H3S and HS2 are metallic. For H3S, we perform nonperturbative calculations of anharmonic effects within the self-consistent harmonic approximation and show that the harmonic approximation strongly overestimates the electron-phonon interaction (λ≈2.64 at 200 GPa) and Tc. Anharmonicity hardens HS bond-stretching modes and softens HS bond-bending modes. As a result, the electron-phonon coupling is suppressed by 30% (λ≈1.84 at 200 GPa). Moreover, while at the harmonic level Tc decreases with increasing pressure, the inclusion of anharmonicity leads to a Tc that is almost independent of pressure. High-pressure hydrogen sulfide is a strongly anharmonic superconductor. © 2015 American Physical Society.

Li Y.,Jiangsu University | Li Y.,Jilin University | Wang Y.,Jilin University | Pickard C.J.,University College London | And 3 more authors.
Physical Review Letters | Year: 2015

Alkali metals exhibit unexpected structures and electronic behavior at high pressures. Compression of metallic sodium (Na) to 200 GPa leads to the stability of a wide-band-gap insulator with the double hexagonal hP4 structure. Post-hP4 structures remain unexplored, but they are important for addressing the question of the pressure at which Na reverts to a metal. Here, we report the reentrant metallicity of Na at the very high pressure of 15.5 terapascal (TPa), predicted using first-principles structure searching simulations. Na is therefore insulating over the large pressure range of 0.2-15.5 TPa. Unusually, Na adopts an oP8 structure at pressures of 117-125 GPa and the same oP8 structure at 1.75-15.5 TPa. The metallization of Na occurs on the formation of a stable and striking body-centered cubic cI24 electride structure consisting of Na12 icosahedra, each housing at its center about one electron that is not associated with any Na ions. © 2015 American Physical Society.

Xiao L.,Jilin University | Jin L.,Jilin University
Astrophysical Journal | Year: 2015

In Paper I, we suggested that the diversity of extrasolar planets might originate from the diversity of molecular cloud cores and specifically illustrated the relationship between semi-major axes of planets in a planetary system and the properties of its progenitor cloud core. In this paper, we investigate the dependence of the mass of a giant planet on the progenitor core properties. We give numerical results of planet masses as a function of the core properties by using the core accretion model of planet formation. Comparing with observations, our model could explain the range and the most frequent values of observed masses of gas giant planets. Our calculations could interpret the observed pileup of gas giants at >1 AU and the distinct deficit of gas giants from ∼0.05 to 1 AU. Our calculations indicate that it is difficult to form gas giant planets outside 20 AU and the intermediate mass planets might be found at ∼15-30 AU as the observing technique advances. We suggest a formation mechanism of super-Jupiters in the framework of the core accretion model of planet formation. A super-Jupiter can form under the condition that a disk is gravitationally unstable ( high viscosity ) when a protoplanet opens the deep gap. Our calculations infer that the upper limit of super-Jupiter masses, the range of semi-major axes, and the occurrence rate of super-Jupiters increase with the central star mass. We find that gas giant planets should commonly exist around various stellar masses. © 2015. The American Astronomical Society. All rights reserved.

Zhang M.,Jilin University | Zhang M.,Beihua University | Liu H.,Jilin University | Li Q.,Jilin University | And 5 more authors.
Physical Review Letters | Year: 2015

We solve the crystal structure of recently synthesized cubic BC3 using an unbiased swarm structure search, which identifies a highly symmetric BC3 phase in the cubic diamond structure (d-BC3) that contains a distinct B-B bonding network along the body diagonals of a large 64-atom unit cell. Simulated x-ray diffraction and Raman peaks of d-BC3 are in excellent agreement with experimental data. Calculated stress-strain relations of d-BC3 demonstrate its intrinsic superhard nature and reveal intriguing sequential bond-breaking modes that produce superior ductility and extended elasticity, which are unique among superhard solids. The present results establish the first boron carbide in the cubic diamond structure with remarkable properties, and these new findings also provide insights for exploring other covalent solids with complex bonding configurations. © 2015 American Physical Society.

Wu J.-H.,Jilin University | Horsley S.A.R.,University of Exeter | Artoni M.,European Laboratory for Nonlinear Spectroscopy | Artoni M.,CNR Institute of Acoustics and Sensors Orso Mario Corbino | La Rocca G.C.,Normal School of Pisa
Light: Science and Applications | Year: 2013

The typically tiny effect of radiation damping on a moving body can be amplified to a favorable extent by exploiting the sharp reflectivity slope at one edge of an optically induced stop-band in atoms loaded into an optical lattice. In this paper, this phenomenon is demonstrated for the periodically trapped and coherently driven cold 87Rb atoms, where radiation damping might be much larger than that anticipated in previous proposals and become comparable with radiation pressure. Such an enhancement could be observed even at speeds of only a few meters per second with less than 1.0% absorption, making radiation damping experimentally accessible. © 2013 CIOMP. All rights reserved.

Fan X.,Jilin University | Zheng W.T.,Jilin University | Kuo J.-L.,Academia Sinica, Taiwan | Singh D.J.,Oak Ridge National Laboratory | Singh D.J.,Jilin University
ACS Applied Materials and Interfaces | Year: 2013

We analyzed the adsorption of Li on graphene in the context of anodes for lithium-ion batteries (LIBs) using first-principles methods including van der Waals interactions. We found that although Li can reside on the surface of defect-free graphene under favorable conditions, the binding is much weaker than to graphite and the concentration on a graphene surface is not higher than in graphite. At low concentration, Li ions spread out on graphene because of Coulomb repulsion. With increased Li content, we found that small Li clusters can be formed on graphene. Although this result suggests that graphene nanosheets can conceivably have a higher ultimate Li capacity than graphite, it should be noted that such nanoclusters can potentially nucleate Li dendrites, leading to failure. The implications for nanostructured carbon anodes in batteries are discussed. © 2013 American Chemical Society.

Sun Y.-L.,Jilin University | Sun Y.-L.,Northwestern University | Yang Y.-W.,Jilin University | Yang Y.-W.,Northwestern University | And 5 more authors.
Small | Year: 2013

Mechanized silica nanoparticles, equipped with pillar[5]arene-[2] pseudorotaxane nanovalves, operate in biological media to trap cargos within their nanopores, but release them when the pH is lowered or a competitive binding agent is added. Although cargo size plays an important role in cargo loading, cargo charge-type does not appear to have any significant influence on the amount of cargo loading or its release. These findings open up the possibility of using pillar[n]arene and its derivatives for the formation of robust and dynamic nanosystems that are capable of performing useful functions. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

The existence of fundamental differences between lung adenocarcinoma (AC) and squamous cell carcinoma (SCC) in their underlying mechanisms motivated us to postulate that specific genes might exist relevant to prognosis of each histology subtype. To test on this research hypothesis, we previously proposed a simple Cox-regression model based feature selection algorithm and identified successfully some subtype-specific prognostic genes when applying this method to real-world data. In this article, we continue our effort on identification of subtype-specific prognostic genes for AC and SCC, and propose a novel embedded feature selection method by extending Threshold Gradient Descent Regularization (TGDR) algorithm and minimizing on a corresponding negative partial likelihood function. Using real-world datasets and simulated ones, we show these two proposed methods have comparable performance whereas the new proposal is superior in terms of model parsimony. Our analysis provides some evidence on the existence of such subtype-specific prognostic genes, more investigation is warranted. © 2015 Suyan Tian.This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Liu S.,Jilin University | Yu B.,Jilin University | Zhang H.,Jilin University | Fei T.,Jilin University | Zhang T.,Jilin University
Sensors and Actuators, B: Chemical | Year: 2014

NO2 gas sensor has been constructed using reduced graphene oxide-ZnO nanoparticles (ZnO-rGO) hybrids as sensing materials. Most importantly, the sensor exhibits higher sensitivity, shorter response time and recovery time than those of the sensor based on rGO, indicating that the sensing performances for NO2 sensing operating at room temperature have been enhanced by introduction of ZnO nanoparticles into rGO matrix. © 2014 Elsevier B.V.

Yu W.,Jilin University | Xu W.,Jilin University | Song H.,Jilin University | Zhang S.,Jilin University
Dalton Transactions | Year: 2014

Oleic acid-capped NaYF4:Yb3+/Er3+ upconversion nanocrystals (UCNCs) with different sizes and crystalline phases were prepared, and their temperature-dependent upconversion luminescence (UCL) and dynamics were studied. It is interesting to observe that the temperature-dependent behavior of UCL for the β-phase (25 nm, 45 nm and bulk) and α-phase (<10 nm) UCNCs is quite different. The UCL intensity of Er3+ ions of the β-phase NaYF4 demonstrates a maximum around 100 K, while the intensity of the α-phase quenches monotonously with elevated temperature (10-400 K). The intensity ratio of 2H11/2-4I15/2 to 4S 3/2-4I15/2, RHS, increases solely with temperature for β-phase NaYF4, while for the α-phase sample, it demonstrates a complex and indeterminate variation as a function of temperature. In the β-phase samples, rising processes were observed in the dynamics of Er3+ ions, while in the α-phase sample, no rising process was observed and the decay processes of Er3+ ions were bi-exponential. The rationale for these different temperature-dependent UCL properties was explained carefully. This journal is © the Partner Organisations 2014.

Ma G.,Jilin University
Pure and Applied Geophysics | Year: 2013

We present two new potential-inversion methods for estimating the depth and the nature (structural index) of the source, which use various combinations of different forms of local wavenumbers and the information about the horizontal location to estimate individually the depth and the nature of a magnetic source. The improved local wavenumber methods only use the horizontal offset and vertical offset of local wavenumbers to estimate the depth and the structural index of the source, so they yield more stable results compared with the results obtained by current methods that require the derivatives of local wavenumbers. Tests conducted with synthetic noise-free and noise-corrupted magnetic data show that the proposed methods can successfully estimate the depth and the nature of the geologic body. However, our methods are sensitive to high-wavenumber noise present in the data, and we reduced the noise effect by upward continuing the noise-corrupted magnetic data. The practical application of the new methods is tested on a real magnetic anomaly over a dike whose source parameters are known and the inversion results are consistent with the true values. © 2012 Springer Basel AG.

Lin Q.,Jilin University
Applied Mechanics and Materials | Year: 2014

In this paper, a novel method which can identify error parameters of accelerometer accurately in the absence of high precision test turntable occasions is provided. The novel method makes use of artificial fish swarm algorithm(AFSA), permits to obtain an accurate identification by taking the acceleration norm as observation, and the standard variance of norm error as optimization index. The identification test is carried out on the platform of fiber optic gyro (FOG) strapdown inertial navigation system (SINS), and the 24-hours static navigation test is also executed. The validity of our method is verified by experiment results, which shows significant profit in practice. © (2014) Trans Tech Publications, Switzerland.

Zhang X.E.,Jilin University
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology | Year: 2012

To study the pathogen and characteristics of viral diarrhea in children in Changchun area. 460 stools specimens were collected from children with acute diarrhea cured in the childrens, hospital of Changchun in 2010. Rotavirus were detected by ELISA, caliceverus and astrovirus were detected by reverse transcription-polymerase chain reactions (RT-PCR), adenovirus were detected by polymerase chain reactions (PCR). A total of 460 specimens were detected. The detection rate of rotavirus, caliceverus, astrovious, adenovious respectively is 35.22%, 20.43%, 9.78%, 3.70%, the detectablerate of mixed infection is 7.61%, children under 2 years old were the major patient. The main genotypes of the virus: rotavirus (G3P[8]), caliceverus (GII-4), astrovious (type I), adenovious (Ad41). Rotavirus is the main pathogen in Changchun. Followed by caliceverus, astrovious, adenovious.

Zhang H.,Shanghai Maritime University | Zhang H.,Ohio State University | Zhang X.,Jilin University | Wang J.,Ohio State University
Vehicle System Dynamics | Year: 2014

In this paper, we investigate the vehicle lateral dynamics stabilisation problem to enhance vehicle handling by considering time-varying longitudinal velocity. The longitudinal velocity is described by a polytope with finite vertices and a novel technique is proposed to reduce the number of vertices. Since the tyre dynamics is nonlinear, the cornering stiffness is represented via the norm-bounded uncertainty. Concerning the time-varying velocity and the nonlinear tyre model, a linear parameter-varying vehicle model is obtained. As the velocity and the states are measurable, a gain-scheduling state-feedback controller is introduced. In the lateral control, the sideslip angle is required to be as small as possible and the yaw rate is constrained to a certain level. Thus, the control objective is to minimise the sideslip angle while the yaw rate is under a prescribed level or constrain both the sideslip angle and the yaw rate to prescribed levels. To consider the transient response of the closed-loop system, the D-stability is also employed in the energy-to-peak control. The optimal controller can be obtained by solving a set of linear matrix inequalities. A nonlinear vehicle model is utilised to illustrate the design procedure and the effectiveness of the proposed design method. Finally, simulations and comparisons are carried out to show the significant advantage of the designed controller. Compared to the open-loop system, the closed-loop system with the designed controller can achieve much smaller sideslip angle and the yaw rate is closer to the desired yaw rate from a reference model. Therefore, the vehicle safety and the handling are both improved in our simulation cases. © 2014 © 2014 Taylor & Francis.

Liu Y.,Jilin University | Wu Z.,Jilin University | Zhang H.,Jilin University
Advances in Colloid and Interface Science | Year: 2014

Two-dimensional (2D) nanomaterials with the thickness at atomic level are promising candidates for a wide range of applications, and now reach the point to create diversified 2D architectures. The colloidal synthesis route is powerful to produce crystalline nanosheets, nanoribbons and nanoplatelets, and the self-assembly strategy is robust to integrate the functionalities of different nano-objects. In this review, we bridge the colloidal synthesis of nanosheets and the 2D self-assembly of nanoclusters (NCs) with the aim to further optimize the physical and chemical properties of 2D nanomaterials. Ultrasmall NCs, the intermediate for synthesizing nanosheets, are highlighted to show the similarity of 2D crystallization and 2D self-assembly. The modification of conventional 2D colloidal synthesis route greatly permits the controlled self-assembly of NCs into free-standing monolayers in colloidal solutions. © 2013 Elsevier B.V.

Xu M.-L.,Jilin University | Liu J.-B.,Jilin University | Lu J.,Jilin University
Applied Spectroscopy Reviews | Year: 2014

We present a review concerning the determination and control of pesticide residues and transformation products in beverages. We review preparation methods using microextraction techniques, which are time-consuming, inexpensive, simple, and endeavor to be environment friendly. Mass spectrometry (MS) and tandem mass spectrometry (MS/MS) technologies are able to detect and quantify matrix-induced chromatographic response effects (matrix effects) accurately, even with the low milligram per kilogram levels. Rapid detection technology is an important tool in food product analysis. We review the technology to analyze the persistence of pesticide residues in beverages in order to effectively control their quality and safety. © 2014 Taylor and Francis Group, LLC.

Jiang J.,Jilin University
World journal of gastroenterology : WJG | Year: 2012

To investigate the role of expressions of Ki-67, p53, epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2) in gastrointestinal stromal tumor (GIST) grading and prognosis. Tumor tissue was collected retrospectively from 96 patients with GIST. Antibodies against Ki-67, p53, EGFR and COX-2 were used for immunohistochemical staining. Tumor grading was designated according to a consensus system and the staining was quantified in 3 categories for each antibody in the statistical analysis. The Ki-67 expression in GISTs was significantly associated with the size of the tumors, mitotic rate and the risk of malignancy (χ(2) = 15.51, P = 0.02; χ(2) = 22.27, P < 0.001; χ(2) = 20.05; P < 0.001). The p53 expression was also significantly correlated with mitotic rate and the risk of malignancy (χ(2) = 9.92, P = 0.04; χ(2) = 9.97; P = 0.04). Over-expression of Ki-67 was strongly correlated with poor survival (χ(2) = 10.44, P = 0.006), but no correlation was found between the expression of p53, EGFR or COX-2 and survival. Multivariate analysis further demonstrated that Ki-67 expression (relative risk = 15.78, 95% CI: 4.25-59.37) could be used as an independent prognostic value for GIST patients. Adjuvant imatinib therapy could improve clinical outcomes in the patients with high risk and intermediate risk of recurrence after complete tumor resections (median survival time: 52 mo vs 37 mo, χ(2) = 7.618, P = 0.006). Our results indicated that the expression of Ki-67 could be used as an independent prognostic factor for GIST patients.

Han X.-G.,Jilin University | Zhang C.-X.,Jilin University
Journal of Chemical Physics | Year: 2010

The phase behavior of physically associating polymer solutions, where the polymer chain contains a small fraction of "stickers" regularly placed along the backbone, is studied using self-consistent field lattice model. Two inhomogenous morphologies are observed. One is a microfluctuation homogenous (MFH) morphology, where the mean-field values of the local average concentrations of polymers φP (r) and stickers φst (r) slightly fluctuate around their respective bulk average values φ- P and φ- st and regularly from site to site. The other is a randomly close-packed micelle (RCPM) morphology. The structure of the micelle in RCPM morphology is similar to that of the "flower micelle" in the telechelic associative polymer system, where stickers are located in the core of the micelle and nonsticky groups in the corona. When φ- P 0.08, if homogenous associating polymer solutions are cooled, MFH morphology appears, and the system entirely changes from homogenous solutions (HS) to MFH morphology; If the solutions are cooled further, RCPM morphology appears. When φ- P <0.08, however, RCPM morphology appears immediately. If φ- P <0.53, a macroscopic phase separation, where the polymer rich phase is RCPM morphology, occurs. If φ- P 0.53, only RCPM morphology is found in the system. A peak appears in the temperature-dependent specific-heat curve CV (Ξ) at each transition point. For the HS-MFH transition, CV (Ξ) has an abrupt increase and a slow decrease, whereas for the MFH-RCPM transition, both the increase and the decrease in CV (Ξ) are slow. Furthermore, the system with only MFH morphology may be trapped in one of the two energy basins in a experimental time scale. However, the appearance of RCPM morphology means that the system is trapped in one of a series of "deeper" energy basins, and it is very difficult to jump off this deep basin into the one of MFH morphology or one of the other RCPM morphologies through thermal fluctuations. © 2010 American Institute of Physics.

Pan X.-L.,Jilin University | Liu W.,Jilin University | Liu J.-Y.,Jilin University
Journal of Physical Chemistry B | Year: 2013

The enzyme α-galactosidase (α-GAL), a member of glycoside hydrolase family 27, catalyzes the removal of a nonreducing terminal α-galactose residue from polysaccharides, glycolipids, and glycopeptides. α-GAL is believed to have the double displacement retaining reaction mechanism. In this work, the glycosylation step catalyzed by human α-GAL was computationally simulated with quantum mechanics/molecular mechanics metadynamics. Our simulations show that the overall catalytic mechanism follows a DN*AN-like mechanism, and the transition state has a oxocarbenium ion like character with a partially formed double bond between the ring oxygen and C5′ carbon atoms. In addition, the galactosyl ring of the substrate follows a conformational itinerary of 4C1 → [E3/4H3]§ → 1S3 along the reaction coordinate. © 2012 American Chemical Society.

He B.-R.,Nagoya University | Ma Y.-L.,Jilin University | Harada M.,Nagoya University
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2015

We study the effects of light scalar mesons on the Skyrmion properties by constructing and examining a mesonic model including pion, rho meson, and omega meson fields as well as two-quark and four-quark scalar meson fields. In our model, the physical scalar mesons are defined as mixing states of the two- and four-quark fields. We first omit the four-quark scalar meson field from the model and find that when there is no direct coupling between the two-quark scalar meson and the vector mesons, the soliton mass is smaller and the soliton size is larger for lighter scalar mesons; when direct coupling is switched on, as the coupling strength increases, the soliton becomes heavy, and the radius of the baryon number density becomes large as the repulsive force arising from the ω meson becomes strong. We then include the four-quark scalar meson field in the model and find that mixing between the two-quark and four-quark components of the scalar meson fields also affects the properties of the soliton. When the two-quark component of the lighter scalar meson is increased, the soliton mass decreases and the soliton size increases. © 2015 American Physical Society. © 2015 American Physical Society.

Li W.,Jilin University | Kim Y.,Jilin University | Li J.,Jilin University | Lee M.,Jilin University
Soft Matter | Year: 2014

The construction of supramolecular polymers has been intensively pursued because the nanostructures formed through weak non-covalent interactions can be triggered by external stimuli leading to smart materials and sensors. Self-assemblies of coordination polymers consisting of metal ions and organic ligands in aqueous solution also provide particular contributions in this area. The main motivation for developing those coordination polymers originates from the value-added combination between metal ions and ligands. This review highlights the recent progress of the dynamic self-assembly of coordination polymers that result from the sophisticated molecular design, towards fabricating stimuli-responsive systems and bio-related materials. Dynamic structural changes and switchable physical properties triggered by various stimuli are summarized. Finally, the outlook for aqueous nanostructures originated from the dynamic self-assembly of coordination polymers is also presented. This journal is © the Partner Organisations 2014.

Fan X.,Jilin University | Zheng W.,Jilin University | Singh D.J.,Jilin University | Singh D.J.,Oak Ridge National Laboratory
Light: Science and Applications | Year: 2014

Light scattering by small particles has a long and interesting history in physics. Nonetheless, it continues to surprise with new insights and applications. This includes new discoveries, such as novel plasmonic effects, as well as exciting theoretical and experimental developments such as optical trapping, anomalous light scattering, optical tweezers, nanospasers, and novel aspects and realizations of Fano resonances. These have led to important new applications, including several ones in the biomedical area and in sensing techniques at the single-molecule level. There are additionally many potential future applications in optical devices and solar energy technologies. Here we review the fundamental aspects of light scattering by small spherical particles, emphasizing the phenomenological treatments and new developments in this field.

Chen K.,CAS Institute of Microbiology | Huang Y.-H.,Jilin University | Chen J.-L.,CAS Institute of Microbiology | Chen J.-L.,Fujian Agriculture and forestry University
Acta Pharmacologica Sinica | Year: 2013

Cancer stem cells (CSCs) have been identified as rare cell populations in many cancers, including leukemia and solid tumors. Accumulating evidence has suggested that CSCs are capable of self-renewal and differentiation into various types of cancer cells. Aberrantregulation of gene expression and some signaling pathways has been observed in CSCs compared to other tumor cells. CSCs are thought tobe responsible for cancer initiation, progression, metastasis, recurrence and drug resistance. The CSC hypothesis has recently attracted much attention due to the potential for discovery and development of CSC-related therapies and the identification of key molecules involved in controlling the unique properties of CSC populations. Over the past several years, a tremendous amount of effort has been invested in the development of new drugs, such as nanomedicines, that can take advantage of the "Achilles' heel" of CSCs by targeting cell-surface molecular markers or various signaling pathways. Novel compounds and therapeutic strategies that selectively target CSCs have been identified, some of which have been evaluated in preclinical and clinical studies. In this article, we review new findings related to the investigation of the CSC hypothesis, and discuss the crucial pathways involved in regulating the development of CSC populations and the advances in studies of drug resistance. In addition, we review new CSC-targeted therapeutic strategies aiming to eradicate malignancies. © 2013 CPS and SIMM.

Zhang H.,Jilin University | Cheng X.,Jilin University | Wang K.,Jilin University | Huang S.,Jilin University | Wang Y.,Jilin University
Angewandte Chemie - International Edition | Year: 2015

A series of highly efficient deep red to near-infrared (NIR) emissive organic crystals 1-3 based on the structurally simple 2′-hydroxychalcone derivatives were synthesized through a simple one-step condensation reaction. Crystal 1 displays the highest quantum yield (Φf) of 0.32 among the reported organic single crystals with an emission maximum (λem) over 710nm. Comparison between the bright emissive crystals 1-3 and the nearly nonluminous compounds 4-7 clearly gives evidence that a subtle structure modification can arouse great property changes, which is instructive in designing new high-efficiency organic luminescent materials. Notably, crystals 1-3 exhibit amplified spontaneous emissions (ASE) with extremely low thresholds. Thus, organic deep red to NIR emissive crystals with very high Φf have been obtained and are found to display the first example of NIR fluorescent crystal ASE. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Zhao Y.,Jilin University | Hu Z.,Jilin University
Chemical Communications | Year: 2012

How structural features observed computationally are connected to excitation-wavelength dependent kinetics observed experimentally remains an unanswered question in the field of ionic liquids. Using molecular dynamics simulation methods and approximated models that simplify the electrostatic interactions in ionic liquids, we discovered that on the timescale shorter than the relaxation time of the photochemical process, the energetic heterogeneity in terms of distribution of excitation energies is the consequence of the structure heterogeneity formed by local arrangement of ions around the solute probe. © 2012 The Royal Society of Chemistry.

Zhang J.,Jilin University | Yan G.,Jilin University
Chaos | Year: 2010

A lattice Boltzmann model is developed for the one- and two-dimensional Burgers-Fisher equation based on the method of the higher-order moment of equilibrium distribution functions and a series of partial differential equations in different time scales. In order to obtain the two-dimensional Burgers-Fisher equation, vector σj has been used. And in order to overcome the drawbacks of "error rebound," a new assumption of additional distribution is presented, where two additional terms, in first order and second order separately, are used. Comparisons with the results obtained by other methods reveal that the numerical solutions obtained by the proposed method converge to exact solutions. The model under new assumption gives better results than that with second order assumption. © 2010 American Institute of Physics.

Zhang J.,Jilin University | Yan G.,Jilin University
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics | Year: 2010

A lattice Boltzmann model with complex distribution function for the complex Ginzburg-Landau equation (CGLE) is proposed. By using multiscale technique and the Chapman-Enskog expansion on complex variables, we obtain a series of complex partial differential equations. Then, complex equilibrium distribution function and its complex moments are obtained. Based on this model, the rotation and oscillation properties of stable spiral waves and the breaking-up behavior of unstable spiral waves in CGLE are investigated in detail. © 2010 The American Physical Society.

Suenaga D.,Nagoya University | He B.-R.,Nagoya University | Ma Y.-L.,Jilin University | Harada M.,Nagoya University
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2015

We explore the mass splitting of heavy-light mesons with chiral partner structure in nuclear matter. In our calculation, we employed the heavy hadron chiral perturbation theory with chiral partner structure, and the nuclear matter is constructed by putting Skyrmions from the standard Skyrme model onto the face-centered cubic crystal and regarding the Skyrmion matter as nuclear matter. We find that, although the masses of heavy-light mesons with chiral partner structure are split in matter-free space and the Skyrmion phase, they are degenerated in the half-Skyrmion phase in which the chiral symmetry is restored globally. This observation suggests that the magnitude of the mass splitting of heavy-light mesons with chiral partner structure can be used as a probe of the phase structure of nuclear matter. © 2015 American Physical Society.

Cheng X.,Jilin University | Zhang H.,Jilin University | Ye K.,Jilin University | Wang Y.,Jilin University
Journal of Materials Chemistry C | Year: 2013

Here we report a bis(2′-hydroxychalcone)beryllium complex Be(HC) 2 that displays yellow fluorescence (λem = 557 nm; Φf = 0.10) in solution. Notably, the solution of this complex produces a non-emissive amorphous thin film (ACQ effect; fluorescent "OFF" state) but brightly emissive crystalline powders (AEE-active; fluorescent "ON" state) with deep red (λem = 678 nm; Φf = 0.27) or near infrared (λem = 700 nm; Φf = 0.20) emission colors and the fluorescent "ON" and "OFF" states can be smoothly transformed into each other by simple engineering processes: mechanical grinding and solvent fuming. © 2013 'The Royal Society of Chemistry.

Zheng K.,Jilin University | Liu Z.,Jilin University | Lv C.,Jilin University | Qin W.,Jilin University
Journal of Materials Chemistry C | Year: 2013

Optical temperature sensing characteristics based on the ultraviolet (UV) upconversion luminescence (UCL) of Gd3+ ions are reported here for the first time. Under 980 nm excitation, the temperature dependence five-photon UV UCL from the 6PJ and 6IJ levels of Gd3+ ions in NaLuF4:Yb3+, Tm3+, Gd3+ microcrystals were investigated systematically. The fluorescence intensity ratios (FIR) of two pairs of thermally coupled levels ( 6P5/2, 6P7/2 and 6I 9/2, 6I7/2) were studied as a function of temperature in a range of 298-523 K. The maximum sensor sensitivities were found to be about 0.0004 K-1 (333 K) and 0.0029 K-1 (298 K) by exploiting the UC emissions from the 6PJ and 6IJ levels, respectively. This suggests that the Gd 3+-based UCL materials are promising prototypes for application as multi-mode probes for use in bio-separation, MRI imaging, optical thermometers, etc. This journal is © The Royal Society of Chemistry 2013.

Sun H.,Northeast Normal University | Zhang F.,Northeast Normal University | Wei H.,Jilin University | Yang B.,Jilin University
Journal of Materials Chemistry B | Year: 2013

Recently, researchers have paid much attention to the toxicity of QDs because of their rapidly increasing application in biomedicine. Recent investigations have indicated that QDs have influences on biological systems at the cellular, subcellular, and protein levels during the processes of imaging and therapeutic applications. The toxicity of QDs is related to their composition, surface functionality, size, shape, and charge, etc. among which composition and surface modification are two important elements. This feature article mainly concentrates on the latest developments in reducing QD toxicity by manipulating their composition and surface modification. Besides the cadmium-based QDs, the assessment of toxicity in vitro and in vivo for other QDs such as carbon dots, graphene QDs, silicon QDs, Ag2Se QDs, CuInS2@ZnS, InP QDs, hybrid QDs of carbon and CdSe@ZnS, etc., is generalized. Each kind of QD has its own advantages. Cadmium-based QDs have broad UV excitation, narrow emission and bright photoluminescence (PL), while cadmium-free ones present low toxicity. In fact, a lot of investigations show that the toxicity of QDs is dose dependent, whatever the composition. Consequently, surface modification becomes very important to reduce toxicity and simultaneously impart biocompatibility, stability, and specificity to QDs. Therefore, the functionalization of QDs with inorganic shells (e.g., CdSe@ZnS, CdSe@SiO2), polymers, bio- or natural macromolecules is summarized. Future research work should concentrate on preparing novel QDs with appropriate surface modification and investigating the long-term influence of QDs on absorption, distribution, metabolism, and elimination in vivo, especially for cadmium-free QDs such as carbon-based QDs, Ag2Se QDs, CuInS 2@ZnS QDs and InP QDs, etc. © 2013 The Royal Society of Chemistry.

Li Y.,Jilin University | Wang X.,Jilin University | Sun J.,Jilin University
Chemical Society Reviews | Year: 2012

In the past two decades, layer-by-layer (LbL) assembly has been proven to be a convenient and versatile method to fabricate functional films. However, using traditional dipping LbL assembly to fabricate micrometer-thick films is time consuming. Compared with ultrathin films, micrometer-thick films prepared by LbL assembly possess enhanced mechanical stability, and allow deposition of a significantly increased amount of materials and the integration of multiple functions. These merits of thick films produced by LbL assembly can result in new functions and allow the functions of ultrathin films fabricated by LbL assembly to be optimized. In this tutorial review, the methods for rapid fabrication of thick polymeric films involving LbL assembly are reviewed. The functions of such films that are relevant to their micrometer thickness are discussed. This journal is © The Royal Society of Chemistry 2012.

Zhang H.,Jilin University | Liu Y.,Jilin University | Yao D.,Jilin University | Yang B.,Jilin University
Chemical Society Reviews | Year: 2012

Inorganic nanoparticles (NPs) with diversified functionalities are promising candidates in future optoelectronic and biomedical applications, which greatly depend on the capability to arrange NPs into higher-order architectures in a controllable way. This issue is considered to be solved by means of self-assembly. NPs can participate in self-assembly in different manners, such as smart self-organization with blended molecules, as the carriers of host molecules for assembly and disassembly with guest molecules, as netpoints to endow the architectures specific functionalities, and so forth. To enhance the structural stability of the as-prepared assembly architectures, polymers have been utilized to create NP-polymer composites. Meanwhile, such a strategy also demonstrates the possibility of integrating the functionalities of NPs and/or polymers by forming regular architectures. The emerging interest in the current optoelectronic and biological areas strongly demands intelligent nanocomposites, which are produced by combination of the excellent functionalities of NPs and the responsiveness of polymers. On the basis of the recent progress in fabricating NP-polymer composites, this critical review summarizes the development of new methods for fabricating regular self-assembly architectures, highlights the reversible assembly and disassembly behavior, and indicates the potential applications. This journal is © The Royal Society of Chemistry 2012.

Single-molecule force spectroscopy (SMFS) opens new avenues for elucidating the structures and functions of large coiled molecules such as synthetic and biopolymers at the single-molecule level. In addition, some of the features in the force-extension curves (i.e. force spectra) are closely related to primary/secondary structures of the molecules being stretched. For example, the long force plateau in the DNA stretching curve is related to the double-helix structure. These features can be regarded as the force fingerprints of individual macromolecules. These force fingerprints can therefore be used as indicators/criteria of single-molecule manipulation during the measurement of some unknown intra- or intermolecular interactions. By comparing the force spectra of a single polymer chain before and after interaction with other molecules, the mode/strength of such molecular interactions can be derived. This Review focuses on recent advances in AFM-based SMFS studies on molecular interactions in both synthetic and biopolymer systems using a single macromolecular chain as probe, including interactions between nucleic acids and proteins, mechanochemistry of covalent bonds, conformation-regulated enzymatic reactions, adsorption and desorption of biopolymers on a flat surface or from the nanopore of a carbon nanotube, and polymer interactions in the condensed state. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Sun J.,Jilin University | Sun J.,Ohio State University | Bhushan B.,Jilin University
RSC Advances | Year: 2012

Nacre (known as mother of pearl) is the iridescent inner shell layer of some mollusks. Nacre is composed of 95 wt% aragonite (a crystallographic form of CaCO 3) and 5 wt% organic materials (proteins and polysaccharides). It is well known that it exhibits high fracture toughness, much greater than that of monolithic aragonite, because of its ingenious structure. It also exhibits energy absorption properties. It has a complex hierarchical microarchitecture that spans multiple length scales from the nanoscale to the macroscale. It includes columnar architectures and sheet tiles, mineral bridges, polygonal nanograins, nanoasperities, plastic microbuckling, crack deflection, and interlocking bricks, which exhibit a remarkable combination of stiffness, low weight and strength. Nacre's special self-assembly characteristics have attracted interest from materials scientists for the development of laminated composite materials, molecular scale self-assembly and biomineralization. This paper reviews the characteristics of hierarchical structure and the mechanical properties of nacre that provide the desired properties, and the latest developments and biomimetic applications. This journal is © 2012 The Royal Society of Chemistry.

Liang Q.,Jilin University
Journal of Nanoparticle Research | Year: 2016

In this work, we show that compositionally controlled Cu2(Sn1–xGex)S3 nanocrystals can be successfully synthesized by the hot-injection method through careful tuning the Ge/(Sn+Ge) precursor ratio. The band gaps of the resultant nanocrystals are demonstrated to be linearly tuned from 1.45 to 2.33 eV by adjusting the composition parameter x of the Ge/(Sn+Ge) ratio from 0.0 to 1.0. The crystalline structures of the resultant NCs have been studied by the X-ray diffraction (XRD), high-resolution transmission electron microscopy (HRTEM), select area electron diffraction (SAED), and Raman spectroscopy. A ligand exchange procedure is further performed to replace the native ligands on the surface of the NCs with sulfur ions. The photoresponsive behavior indicates the potential use of as-prepared Cu2(Sn1–xGex)S3 nanocrystals in solar energy conversion systems. The synthesis of compositionally controlled Cu2(Sn1–xGex)S3 nanocrystals reported herein provides a way for probing the effect of Ge inclusion in the Cu-Sn-S system thin films. © 2016, The Author(s).

Wang C.,Jilin University | Xiao B.,Jilin University | Ding Y.-H.,Jilin University
ChemPhysChem | Year: 2012

Many outstanding properties of graphene are blocked by the existence of structural defects. Herein, we propose an important healing mechanism for the growth of graphene, which is produced via plasma-enhanced chemical vapor decomposition (PECVD), that is, the healing of graphene with single vacancies by decomposed CH 4 (hydrocarbon radical CH x, x=1, 2, 3). The healing processes undergo three evolutionary steps: 1) the chemisorption of the hydrocarbon radicals, 2) the incorporation of the C atom of the hydrocarbon radicals into the defective graphene, accompanied by the adsorption of the leaving H atom on the graphene surface, 3) the removal of the adsorbed H atom and H 2 molecule to generate the perfect graphene. The overall healing processes are barrierless, with a huge released heat of 530.79, 290.67, and 159.04 kcal mol -1, respectively, indicative of the easy healing of graphene with single vacancies by hydrocarbon radicals. Therefore, the good performance of the PECVD method for the generation of graphene might be ascribed to the dual role of the CH x (x=1, 2, 3) species, acting both as carbon source and as defect healer. Growing well: Many outstanding properties of graphene are blocked by the existence of structural defects (see picture). An important healing mechanism that takes place during the growth of this material via plasma-enhanced chemical vapor decomposition (PECVD) is proposed. The three-step process is based on the incorporation of C atoms from hydrocarbon radicals into the single-vacancy defects of graphene. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Qian Z.-H.,Jilin University | Wang Y.-J.,Jilin University
Tien Tzu Hsueh Pao/Acta Electronica Sinica | Year: 2012

Based on analyzing IoT two basic concepts, architecture of IoT is proposed, which includes underlayer network distribution, convergence gateway access, inter-connected network integration and terminal user application. In the architecture, a protocol structure of IoT is given, which consists of network protocol layers, network control platform and application terminal platform, and the key technologies for IoT have been discussed concerning hardware and software. Six development conceptions of future IoT have been presented based on summarizing the existing problems of IoT in standards, technologies, security and application.

Yin X.,Jilin University | Meng F.,Jilin University | Wang L.,Jilin University
Journal of Materials Chemistry C | Year: 2013

A class of new compounds consisting of a tetraphenylethene (TPE) core and hydrophilic peripheral oligo(ethylene glycol) chains was synthesized. These newly synthesized compounds showed aggregation-induced emission (AIE) nature which originated from the TPE core, and their peripheral oligo(ethylene glycol) chains impart water-solubility for the whole molecules. These compounds exhibit a lower critical solution temperature behavior in water. The phase transition temperature of TPE derivatives increases with the increase in the length of oligo(ethylene glycol) chains. By taking advantage of the AIE properties and thermosensitivity, these compounds are able to sense temperature by showing different emission intensities. When being heated above its phase-transition temperature, these compounds start to aggregate, which results in the restricted intramolecular rotation of the TPE moiety. Consequently, the aqueous solutions of these compounds show a stronger fluorescence. The temperature-induced fluorescence change is highly reversible. © 2013 The Royal Society of Chemistry.

Shi Z.,Jilin University | Zhao X.,Jilin University | Huang X.,Jilin University
Journal of Materials Chemistry C | Year: 2013

Based on first-principles computations, the geometries, stabilities, electronic and magnetic properties of fully and partially hydrogenated boron nitride nanoribbons (BNNRs) were investigated. Our results from the theoretical computation revealed that the boat and stirrup configurations were the most stable ones among the boat, chair and stirrup configurations for zigzag and armchair fully hydrogenated BNNRs, respectively. The fully hydrogenated 10-zBNNRs exhibited energetically degenerated ferromagnetic (FM) and ferrimagnetic (MFM) states for the boat and chair configurations. In the FM state, they showed metallic behavior, whereas in the MFM state, only the energy levels in the spin-down channel cross the Fermi-level, indicating the corresponding half-metallic feature. Moreover, intrinsic MFM half-metallic behavior can be observed in stirrup fully hydrogenated 10-zBNNRs. However, all of the fully hydrogenated 15-aBNNRs were nonmagnetic wide-band-gap semiconductors. By hydrogenating the zigzag BNNRs (zBNNRs) from the edge(s) step by step in a boat manner, we provide an effective approach to enrich the electronic and magnetic properties of zBNNRs and the transition of NM wide-gap semiconductor → NM narrow-gap semiconductor → energetically degenerated FM/MFM(AFM) metal/half-metal → FM metal → MFM half-metal can be achieved by controlling the hydrogenation patterns and ratios. These appealing features, especially the diverse electronic and magnetic transitions, in the unitary BNNR-based nanostructures may provide tremendous potential applications for integrated multi-functional and spintronic nanodevices. © 2013 The Royal Society of Chemistry.

Zhao Y.,Jilin University | Hu Z.,Jilin University
Journal of Physical Chemistry B | Year: 2013

Over the past decade, there has been much controversy regarding the microscopic mechanism by which the π-electron-rich carbon nanomaterials such as graphene and carbon nanotubes can be dispersed in ionic liquids. Through a combination of a quantum mechanical calculation on the level of density functional theory, an extensive molecular dynamics study on the time scale of microseconds, and a kinetic analysis at the experimental time scale, we have demonstrated that collective van der Waals forces between ionic liquids and graphene are able to describe both the short-ranged cation-π interaction and the long-ranged dispersion interaction and this microscopic interaction drives two graphene plates trapped in their metastable state while two graphene plates easily self-assemble into graphite in water. © 2013 American Chemical Society.

Zhao Y.Y.,Jilin University
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology | Year: 2013

To construct a short hairpin (sh)RNA targeting the gene encoding the MDM2 oncoprotein in order to investigate its role in human hepatocellular carcinoma (HCC) and its potential for use as a gene therapy strategy to inhibit HCC growth in vivo. Small interfering (si)RNAs were designed targeting the MDM2 gene (siMDM2-1 and siMDM2-2) and unrelated sequences (negative control) and cloned into the expression plasmid pGCSilencer-U6-neo-GFP. A HCC mouse model was established by subcutaneous inoculation of HepG2 cells (2 x 10(6) in 0.2 ml) into 20 nude mice. The inoculated mice were divided into four equal groups for tumor-localized injections of saline, negative control siRNA plasmid, siMDM2-1 plasmid, and siMDM2-2 plasmid. Tumor growth was observed daily (by caliper measurement) for one month, when mice were sacrificed by cervical dislocation. The tumor mass was resected for analysis of tumor inhibition rate (% = [(average tumor weight of control group - average tumor weight of treatment group) / average tumor weight of control group x 100]) and effects on MDM2 and p53 mRNA and protein expression (by reverse transcription- PCR and western blotting, both normalized to beta-actin). Significance of between-group differences was assessed by one-way ANOVA or LSD test; pairwise comparisons were made by the Chi-squared test. siMDM2-1 and siMDM2-2 suppressed the xenografted tumor growth remarkably (60.6% and 54.6% inhibition rates, respectively), significantly reduced the expression ofMDM2 gene (62.8% and 61.6%) and protein (60.7% and 59.5%), and significantly increased p53 gene (47.1% and 45.6%) and protein (45.9% and 44.3%) (all, P < 0.05). shRNA-mediated silencing of the MDM2 gene effectively inhibits HCC tumorigenesis of subcutaneously xenografted HepG2 cells in nude mice, and the mechanism may involve p53.

Wang Z.,Jilin University | Yu J.,Jilin University | Xu R.,Jilin University
Chemical Society Reviews | Year: 2012

Zeolites are an important class of materials which are widely used in industry as catalysts, adsorbents and ion-exchangers. Their superior properties are closely related to their unique porous framework structure, as well as composition and morphology. The ever-growing needs for zeolitic materials in applications inspire us to think of the rational synthesis of zeolites with desired structures and properties. However, rationalization of zeolitic materials remains one of the most challenging issues in the zeolite research field due to their unclear formation mechanism. Despite this, many efforts have been devoted to synthesize zeolites in a more rational way. In this tutorial review, first, we demonstrate how the geometrical characteristics of zeolite frameworks affect the catalytic performances of the resulting materials; then, we present recent advances in synthetic innovations to target materials, and we further highlight the developments in computer simulations toward ab initio design and synthesis; finally, the future perspective on the rational synthesis of zeolitic materials with desired functions and structures will be described. © 2012 The Royal Society of Chemistry.

Xue X.,Jilin University
Wei sheng wu xue bao = Acta microbiologica Sinica | Year: 2013

To sequence the complete genome of CVS-11 strain and establish a reverse genetic system of CVS-11 to further study its pathogenic mechanism, virulence genes and antigenic sites. We amplified12 fragments covering the complete genome of the CVS-11 strain by RT-PCR, and then cloned to pEASY-Blunt vector for sequencing the complete genome of CVS-11. We analyzed single restriction enzyme sites of the full length cDNA of the CVS-11 strain by DNAMAN and designed 4 pairs of specific primers. We amplified the full-length cDNA of CVS-11 by RT-PCR. We obtained four fragments and cloned into pcDNA3. 1. We named the full-length cDNA plasmid pcDNA3. 1-CVS-11. We also cloned helper plasmids pcDNA3.1-N, P, L and G expressing N, P, L and G protein of CVS-11 strain, respectively. We co-transfected NA cells with the full-length plasmid and four helper plasmids. We identified the supernatant of the transfected and then passaged NA cells by immunofluorescence staining and RT-PCR and found the recombinant virus rCVS-11 rescued successfully. Sequencing results showed that the complete genome of CVS-11 was composed of 11 927 nucleotides. The complete genome of CVS-11 encoded 5 structure proteins and gene array was the same as other reported rabies viruses. We successfully constructed a reverse genetic system of CVS-11, namely the full length plasmid pcDNA3. 1-CVS-11 and 4 help plasmids pcDNA3. 1-N, P, L, G and rescued the rCVS-11 from a full-length infectious cDNA clone. The reverse genetic system of the CVS-11 strain laid the foundation for future studies on rabies virus.

Xu H.,Jilin University | Yu B.,Beijing Institute of Technology
Expert Systems with Applications | Year: 2010

Email has become one of the fastest and most economical forms of communication. Email is also one of the most ubiquitous and pervasive applications used on a daily basis by millions of people worldwide. However, the increase in email users has resulted in a dramatic increase in spam emails during the past few years. This paper proposes a new spam filtering system using revised back propagation (RBP) neural network and automatic thesaurus construction. The conventional back propagation (BP) neural network has slow learning speed and is prone to trap into a local minimum, so it will lead to poor performance and efficiency. The authors present in this paper the RBP neural network to overcome the limitations of the conventional BP neural network. A well constructed thesaurus has been recognized as a valuable tool in the effective operation of text classification, it can also overcome the problems in keyword-based spam filters which ignore the relationship between words. The authors conduct the experiments on Ling-Spam corpus. Experimental results show that the proposed spam filtering system is able to achieve higher performance, especially for the combination of RBP neural network and automatic thesaurus construction. © 2009 Elsevier Ltd. All rights reserved.

Guli M.,University of Bristol | Guli M.,Jilin University | Lambert E.M.,University of Bristol | Li M.,University of Bristol | Mann S.,University of Bristol
Angewandte Chemie - International Edition | Year: 2010

(Figure Presented) Redox reactions were utilized to deposit periodically arranged Ag and Au nano-structures within the solvent channels of cross-linked lysozyme crystals (see picture for Ag-doped lysozyme crystals). The ability to crystallize lysozyme in various polymorphic forms provides an opportunity to tailor the architecture of the metalized nanostructures through judicious choice of the protein lattice. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.

Sun J.,Jilin University | Sun J.,Ohio State University | Bhushan B.,Ohio State University
RSC Advances | Year: 2012

Insects of extremely small size have evolved to solve many problems. Their structure and mechanical properties information can be utilized to mimic them for industrial applications. Since beetle (Coleoptera, an order of insects) wings exhibit special functionalities, they have sparked worldwide research attention. Beetle wings are composed of a forewing (also known as elytron) and a hind wing. The elytra are rigid. A beetle's functional wings, which allow flying, are the hind wings. The elytra have an ingenious structure with superhydrophobic characteristics, a structural coloration and anti-adhesion characteristics. Their inner structure helps to provide light mass and high strength. The rotation angle and wing locking system of elytra are important features which increase beetles' ability to fly; they may furnish an insight for portable micro air vehicles (MAVs) and also provide inspiration for the design of bioinspired deployable systems. Studies of the structural and mechanical properties in biological systems may improve the understanding of natural solutions and advance the design of novel artificial materials. In this paper, the structure, mechanical properties and their relationship to function of beetle wings are discussed. Examples of bioinspired structures and materials are also presented. © 2012 The Royal Society of Chemistry.

Wang Y.,Jilin University | Wang W.,Yantai Wanhua Polyurethanes Co. | Song W.,Jilin University
Electrochimica Acta | Year: 2011

Cobalt oxide-doped copper oxide composite nanofibers (CCNFs) were successfully achieved via electrospinning followed by thermal treatment processes and then exploited as active electrode material for direct enzyme-free fructose detection. The morphology and the structure of as-prepared samples were investigated by X-ray diffraction spectrum (XRD) and scanning electron microscopy (SEM). The electrocatalytic activity of CCNFs films towards fructose oxidation and sensing performances were evaluated by conventional electrochemical techniques. Cyclic voltammetry (CV) and chronoamperometry (I-t) revealed the distinctly enhanced sensing properties towards fructose compared to pure copper oxide nanofibers (CNFs), i.e., showing significantly lowered overpotential of 0.30 V, ultrafast (1 s) and ultrasensitive (18.988 μA mM-1) current response in a wide linear range of 1.0 × 10 -5 M to 6.0 × 10-3 M with satisfied reproducibility and stability, which could be ascribed to the synergic catalytic effect of the binary CuO/Co3O4 composite nanofibers and the highly porous three-dimensional network films structure of the CCNFs. In addition, a good selectivity for fructose detection was achieved. Results in this work demonstrated that CCNFs is one of the promising catalytic electrode materials for enzymeless fructose sensor fabrication. © 2011 Elsevier Ltd. All Rights Reserved.

Yang H.,University of Colorado at Boulder | Liu Z.,Jilin University | Zhang W.,University of Colorado at Boulder
Advanced Synthesis and Catalysis | Year: 2013

A series of triphenolsilane-coordinated molybdenum(VI) propylidyne catalysts has been developed, which are resistant to small alkyne polymerization and compatible with various functional groups (including phenol substrates). The catalysts remain active in solution for days at room temperature (months at -30 °C). The catalysts are also compatible with 5 Å molecular sieves (small alkyne scavengers), and have enabled the homodimerization of small alkyne substrates at 40-70 °C in a closed system, with dimer products being obtained in 76-96% yields. A shape-persistent aryleneethynylene macrocycle (11) was also prepared on a gram scale with 0.5 mol% catalyst loading, in almost quantitative yield. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Chen X.F.,Jilin University | Lian J.S.,Jilin University | Jiang Q.,Jilin University
Physical Review B - Condensed Matter and Materials Physics | Year: 2012

First-principles calculations based on all-electron density functional theory are performed on hydrogenated graphene/boron nitride (BN) bilayer and graphene/BN multilayers to exploit the effects of the heterogeneous interface and external bias voltage on controlling their electronic properties. After hydrogenation, the emerging of the dipoles at the interface induced by the charge transfer between the graphene and the BN layer introduces a built-in potential difference, which plays a critical role in determining the band gaps of the resulting system. Tuning this internal potential difference through changing the number of BN layers or an external bias allows continuous modulation of the band gaps and leads to a linear transition from semiconductors to metals. © 2012 American Physical Society.

Liu M.,Qingdao University of Science and Technology | Zhang J.,Qingdao University of Science and Technology | Liu J.,Nanjing University of Science and Technology | Yu W.W.,Jilin University
Journal of Catalysis | Year: 2011

Stable poly(N-vinyl-2-pyrrolidone)-stabilized Pt/Ru colloidal nanoparticles (PVP-Pt/Ru) were prepared via ethanol reduction of H2PtCl 66H2O and RuCl3nH2O. The average diameters of the nanoparticles with different molar ratio of Pt/Ru were in a range of 2.1-2.8 nm with narrow size distributions. X-ray photoelectron spectroscopy verified that both Pt and Ru were in the metallic state and Ru was rich on the surface. These nanoparticles were employed to selectively hydrogenate ortho-chloronitrobenzene at 298 K and 0.1 MPa hydrogen pressure. They showed high activity [TOF was in the range of 0.8-5.3 × 10 -2 molo-CNB/(molM,surface atom) s] and high selectivity (93-99%) to ortho-chloroaniline (o-CAN) for the reaction, which were composition-dependent. The selectivity to o-CAN monotonously increased, but the activity of the catalyst decreased with the increasing proportion of Ru in Pt/Ru colloidal catalysts. PVP-1Pt/4Ru nanoparticles exhibited the highest selectivity of 99.0% to o-CAN at a complete conversion. © 2010 Elsevier Inc. All rights reserved.

Dong Y.,Jilin University | Junde H.,Jilin University
Nuclear Data Sheets | Year: 2014

The 2005 evaluation for A=54 (2006Hu08) has been updated. Detailed experimental nuclear structure data and decay data for all nuclei with mass chain A=54 are presented in this current evaluation. The new data and information are given in following datasets:. 54Ca: 9Be(76Ge, X) and Be(55Sc, p), (56Ti, 2p)54Sc: 54Ca β- decay and 54Sc IT decay54Ti: 54Sc β- decay54Cr: 54Mn ε decay, 56Fe(μ, nupng), and 238U(64Ni, Xγ)54Mn: 51V(20Ne, Xγ), 55Mn(p, pn), and 56Fe(μ, nu2ng)54Fe: 58Ni α decay, 9Be(55Co, Xγ), 54Fe(e, e'), 54Fe(p, p'), and Coulomb Excitation54Co: 54Ni ε decay, 55Cu εp decay, 28Si(32S, αpnγ), 54Fe(p,n), and 54Fe(3He, t)54Ni: 54Ni IT decay, 55Zn εp decay, 9Be(55Ni, Xγ), and 24Mg(32S, Xγ)54Zn: Ni(58Ni, X). © 2014.

The groundwater flow system is typical dissipative structure system, and its evolution can be described with system information entropies. The information entropies of groundwater in Shijiazhuang City had been calculated between 1960 and 2005, and the results show that the entropies have a decreasing trend throughout the research period, and they can be divided into our stages based on the groundwater flow system entropy variation as follows: entropy steady period (1960-1965), entropy decreasing period (1965-1980), entropy increasing period (1980-1995) and secondary entropy decreasing period (1995-2005); understanding the major and significant driving the pattern changing forces of groundwater levels is essential to groundwater management,. A new method of grey correlation analysis has been presented, and the results show that, the grey correlation grade between groundwater flow system information entropies and precipitation series is γ01 = 0.749, the grey correlation grade between groundwater flow system information entropies and groundwater withdrawal series is γ02 = 0.814, as the groundwater withdrawal is the main driving force of groundwater flow system entropy variation; based on the numerical simulation results, information entropy increased with artificial recharge, and a smaller recharge water volume would enhance the information entropy drastically, but then doubled water would not increase the information correspondingly, which could be useful to assess the health state of groundwater flow systems. © 2014 by the authors; licensee MDPI, Basel, Switzerland.

Shao C.-B.,Jilin University | Ding Y.-H.,Jilin University
Physical Chemistry Chemical Physics | Year: 2010

Molecules with hypercoordinate planar centers have continued to receive enthusiastic attention due to their violation of the traditional models of three-dimensional chemical bonding and maximum tetracoordination. These electronic exotic but structurally aesthetic species have been optimistically conceived as building blocks in cluster-assembly for bulky materials. Recently, the planar hexacoordinate nitrogen (phN) unit, NB6 -, has been theoretically incorporated into a series of sandwich-like transition-metal compounds. However, the intrinsic stability of NB6 - in both gas-phase and assembly has not been tackled, though it is the key factor for predicting the viability of any molecules. In this paper, at the CCSD(T)/6-311+G(2df)//B3LYP/6-311+G(d)+ZPVE level, we investigate for the first time the thermodynamic and kinetic stability of the phN unit, NB 6 -, in both free and assembled ([NB6] 2Fe) forms. The calculated least barrier height of phN towards conversion is 9.2 and 4.4 kcal mol-1 in free and assembled forms, respectively. Most importantly, the phN structure is thermodynamically rather unstable, by 102.8 and 162.1 kcal mol-1 higher than the respective lower-lying conversion isomers. Therefore, in view of the combined thermodynamic and kinetic consideration, we propose that isolation of the phN structure of NB6 - in either gas phase or assembly is unlikely. The present results manifest that for predicting any viable molecule with exotic structures, investigation of its "intrinsic stability" is highly necessary. The maintenance of the phN-NB6 - is discussed at the 6-311+G(d)-B3LYP, MP2, CCSD and CCSD(T) optimization levels in comparison with the isoelectronic and milestone phC-CB6 2-. © 2010 the Owner Societies.

Ni J.-Y.,Sun Yat Sen University | Liu S.-S.,Jilin University | Xu L.-F.,Sun Yat Sen University | Sun H.-L.,Sun Yat Sen University | Chen Y.-T.,Sun Yat Sen University
World Journal of Gastroenterology | Year: 2013

AIM: To compare radiofrequency ablation (RFA) and transcatheter arterial chemoembolization (TACE) with RFA monotherapy in hepatocellular carcinoma (HCC). METHODS: We searched PubMed, Medline, Embase and Chinese databases (CBMdisc and Wanfang data) for randomized controlled trails comparing RFA plus TACE and RFA alone for treatment of HCC from January 2000 to December 2012. The overall survival rate, recurrence-free survival rate, tumor progression rate, and safety were analyzed and compared. The analysis was conducted on dichotomous outcomes and the standard meta-analytical techniques were used. Pooled odds ratios (ORs) with 95%CIs were calculated using either the fixed-effects or random-effects model. For each meta-analysis, the χ2 and I2 tests were first calculated to assess the heterogeneity of the included trials. For P < 0.05 and I2 > 50%, the assumption of homogeneity was deemed invalid, and the random-effects model was used; otherwise, data were assessed using the fixed-effects model. All statistical analysis was conducted using Review manager (version 4.2.2.) from the Cochrane collaboration. RESULTS: Eight randomized controlled trials were identified as eligible for inclusion in this analysis and included 598 patients with 306 treated with RFA plus TACE and 292 with RFA alone. Our data analysis indicated that RFA plus TACE was associated a significantly higher overall survival rate (OR1-year = 2.96, 95%CI: 1.84-7.74, P < 0.001; OR2-year = 3.72, 95%CI: 1.24-11.16, P = 0.02; OR3-year = 2.65, 95%CI: 1.81-3.86, P < 0.001) and recurrence-free survival rate (OR3-year = 3.00, 95%CI: 1.75-5.13, P < 0.001; OR5-year = 2.26, 95%CI: 1.43-3.57, P = 0.0004) vs that of RFA alone. The tumor progression rate in patients treated with RFA alone was higher than that of RFA plus TACE (OR = 0.60, 95%CI: 0.42-0.88, P = 0.008) and there was no significant difference on major complications between two different kinds of treatment (OR = 1.20, 95%CI: 0.31-4.62, P = 0.79). Additionally, the meta-analysis data of subgroups revealed that the survival rate was significantly higher in patients with intermediate- and large-size HCC underwent RFA plus TACE than in those underwent RFA monotherapy; however, there was no significant difference between RFA plus TACE and RFA on survival rate for small HCC. CONCLUSION: The combination of RFA with TACE has advantages in improving overall survival rate, and provides better prognosis for patients with intermediate-and large-size HCC. © 2013 Baishideng. All rights reserved.

ABSTRACT: Study Design. Meta-analysisObjective. The purpose of this study was to answer the following questions: (1) Does heterotopic ossification (HO) negatively influence clinical outcomes following cervical total disc replacement (CTDR)? (2) Should patients be classified into HO and non-HO groups? (3) Is there a more rational classification?Summary of Background Data. HO has emerged as a common complication following CTDR and has been an important reason for reoperation, thus limiting the use of the surgery. However, the influence of HO on clinical outcomes following CTDR has not been well established.Methods. A meta-analysis was conducted with studies identified by searches of MEDLINE, EMBASE, and the Cochrane Library. We calculated the weighted mean differences (WMD) of the visual analog scale (VAS) pain, neck disability index (NDI) and range of motion (ROM). Patients were classified into two groups under three classifications based on the grade of HO. Results were pooled using a fixed effect model or a random effects model, according to the heterogeneity.Results. There were significant differences in ROM uner all three classifications. The VAS pain and NDI between the patients with and without HO showed no significant difference following CTDR. Significant differences in VAS pain were observed when patients were classified into a “high-grade HO” group (McAfee grades 3 or 4 HO) and a “low-grade HO” group (McAfee grade 0, 1, or 2 HO).Conclusions. The presence of HO is not associated with clinical outcomes following CTDR. However, the severity of HO actually impacts clinical outcomes in an inverse manner which needs further investigation. Itʼs inappropriate to classify patients based on the presence of heterotopic ossification, further studies of the classifications (ROM-affecting HO vs. ROM-preserving HO; high-grade HO vs. low-grade HO) and cervical stability following CTDR are needed. © 2015 by Lippincott Williams & Wilkins

Fine N.M.,Mayo Medical School | Chen L.,Mayo Medical School | Chen L.,Jilin University | Bastiansen P.M.,Mayo Medical School | And 4 more authors.
Circulation: Cardiovascular Imaging | Year: 2013

Background-Although right ventricular (RV) dysfunction is a major determinant of outcome in patients with pulmonary hypertension (PH), the optimal measure of RV function is poorly defined. We hypothesized that RV strain measured by speckle-tracking echocardiography predicts outcome in PH over a broad range of pulmonary pressures. Methods and Results-Prospective peak RV longitudinal systolic strain measurement was performed on 575 patients (mean age, 56±18 years; 63% women) referred for echocardiography for known or suspected PH. Survival status was assessed over a median of 16.5 (interquartile range, 7.6-20.0) months. There were 406 patients with PH (71%) (74% group 1, 14% group 3, and 12% group 4) and 169 patients without evidence of PH (29%). Among patients with PH, 46% were World Health Organization functional class III-IV. The mean RV strain was -21.2±6.7% for all patients. RV strain declined with worse functional class, shorter 6-minute walk distances, higher N-terminal pro-B-type natriuretic peptide levels, and the presence of right heart failure. RV strain predicted outcome across pulmonary pressures and groups of PH. Eighteen-month survival was 92%, 88%, 85%, and 71% according to RV strain quartile (P<0.001), with a 1.46 higher risk of death (95% confidence interval, 1.05-2.12) per 6.7% decline in RV strain. RV strain predicted survival when adjusted for pulmonary pressure, pulmonary vascular resistance, and right atrial pressure and provided incremental prognostic value over conventional clinical and echocardiographic variables. Conclusions-Quantitative assessment of RV free-wall systolic strain is feasible and is a powerful predictor of the clinical outcome of patients with known or suspected PH. © 2013 American Heart Association, Inc.

Zhang G.,Jilin University | Zhao L.,Jilin University
Materials Letters | Year: 2012

Single-crystalline nickel nanopolyhedra with edge lengths about 60 nm were synthesized through a simple solvothermal method. Further adjusting the experimental parameters, two kinds of one-dimensional (1D) nickel submicron chains with quite different surfaces were also obtained. Here, the dosages of tetramethylammonium hydroxide and hydrazine hydrate play important roles in controlling the morphologies. The formation mechanism of nickel crystals with different shapes was deeply investigated. Moreover, it can be proved one more time by our experimental results that the morphologies of magnetic crystals have some influences on their magnetic properties. By magnetic measurement, the saturation magnetization of the nickel nanopolyhedra and submicron chains is respectively 48.2 and 57.3 emu/g. © 2012 Elsevier B.V. All rights reserved.

Jiang T.,Jilin University | Qin W.,Jilin University | Zhao D.,Jilin University
Materials Letters | Year: 2012

CaF 2:Yb,Tm nano- and micro-crystals with different sizes were synthesized by a simple hydrothermal method. All the nanocrystals present intense ultraviolet (UV), visible, and near infrared (NIR) upconversion (UC) luminescence. The relationship between the UC luminescence intensities and the sample sizes from 50 nm to 1200 nm was investigated. The UV UC luminescence intensity of the sample with the particle size around 600 nm was the highest among all the samples, but the NIR UC luminescence intensity of the sample was the lowest. Our experimental results indicated that there was a size between 50 nm and microscale at which the UV emission intensity was the highest for CaF 2 matrix. The size-dependent UC luminescence was proposed and analyzed based on experimental data. © 2012 Elsevier B.V. All rights reserved.

Li C.,Jilin University | Lian J.S.,Jilin University | Jiang Q.,Jilin University
Physical Review B - Condensed Matter and Materials Physics | Year: 2011

The band structures, partial density of states, and electronic configuration of several AB2C full-Heusler compounds have been simulated using local-density approximation (LDA)+U. Results show that full-Heusler compounds with half-filled d orbitals and d5d5s2p6 electronic structures can also form topological insulators, which will double the range of topological insulator candidates. The band structures of full-Heusler compounds are affected by the covalent bondings of A-B and B-C jointly. The spin-up electrons and spin-down electrons influence the orbitals respectively, which leads to the magnetism of the materials, and all full-Heusler compounds with the magnetic moments ∼9μB are antiferromagnets, which may provide a new design of a tunable optical modulator. © 2011 American Physical Society.

Yang B.,Jilin University | Liu J.,Hong Kong Baptist University | Liu D.,Jilin University
IEEE Transactions on Systems, Man, and Cybernetics, Part B: Cybernetics | Year: 2012

Complex network theory provides a means for modeling and analyzing complex systems that consist of multiple and interdependent components. Among the studies on complex networks, structural analysis is of fundamental importance as it presents a natural route to understanding the dynamics, as well as to synthesizing or optimizing the functions, of networks. A wide spectrum of structural patterns of networks has been reported in the past decade, such as communities, multipartites, bipartite, hubs, authorities, outliers, and bow ties, among others. In this paper, we are interested in tackling the challenging task of characterizing and extracting multiplex patterns (multiple patterns as mentioned previously coexisting in the same networks in a complicated manner), which so far has not been explicitly and adequately addressed in the literature. Our work shows that such multiplex patterns can be well characterized as well as effectively extracted by means of a granular stochastic blockmodel, together with a set of related algorithms proposed here based on some machine learning and statistical inference ideas. These models and algorithms enable us to further explore complex networks from a novel perspective. © 2006 IEEE.

Gao J.,Jilin University | Gao J.,University of Minnesota | Truhlar D.G.,University of Minnesota | Wang Y.,University of Minnesota | And 4 more authors.
Accounts of Chemical Research | Year: 2014

ConspectusMolecular mechanical force fields have been successfully used to model condensed-phase and biological systems for a half century. By means of careful parametrization, such classical force fields can be used to provide useful interpretations of experimental findings and predictions of certain properties. Yet, there is a need to further improve computational accuracy for the quantitative prediction of biomolecular interactions and to model properties that depend on the wave functions and not just the energy terms. A new strategy called explicit polarization (X-Pol) has been developed to construct the potential energy surface and wave functions for macromolecular and liquid-phase simulations on the basis of quantum mechanics rather than only using quantum mechanical results to fit analytic force fields. In this spirit, this approach is called a quantum mechanical force field (QMFF).X-Pol is a general fragment method for electronic structure calculations based on the partition of a condensed-phase or macromolecular system into subsystems ("fragments") to achieve computational efficiency. Here, intrafragment energy and the mutual electronic polarization of interfragment interactions are treated explicitly using quantum mechanics. X-Pol can be used as a general, multilevel electronic structure model for macromolecular systems, and it can also serve as a new-generation force field. As a quantum chemical model, a variational many-body (VMB) expansion approach is used to systematically improve interfragment interactions, including exchange repulsion, charge delocalization, dispersion, and other correlation energies. As a quantum mechanical force field, these energy terms are approximated by empirical functions in the spirit of conventional molecular mechanics. This Account first reviews the formulation of X-Pol, in the full variationally correct version, in the faster embedded version, and with systematic many-body improvements. We discuss illustrative examples involving water clusters (which show the power of two-body corrections), ethylmethylimidazolium acetate ionic liquids (which reveal that the amount of charge transfer between anion and cation is much smaller than what has been assumed in some classical simulations), and a solvated protein in aqueous solution (which shows that the average charge distribution of carbonyl groups along the polypeptide chain depends strongly on their position in the sequence, whereas they are fixed in most classical force fields). The development of QMFFs also offers an opportunity to extend the accuracy of biochemical simulations to areas where classical force fields are often insufficient, especially in the areas of spectroscopy, reactivity, and enzyme catalysis. © 2014 American Chemical Society.

Zeng T.,University of Waterloo | Li H.,Jilin University | Roy P.-N.,University of Waterloo
Journal of Physical Chemistry Letters | Year: 2013

We present the first simulation study of bosonic clusters doped with an asymmetric top molecule. The path-integral Monte Carlo method with the latest methodological advance in treating rigid-body rotation [Noya, E. G.; Vega, C.; McBride, C. J. Chem. Phys.2011, 134, 054117] is employed to study a para-water impurity in para-hydrogen clusters with up to 20 para-hydrogen molecules. The growth pattern of the doped clusters is similar in nature to that of pure clusters. The para-water molecule appears to rotate freely in the cluster. The presence of para-water substantially quenches the superfluid response of para-hydrogen with respect to the space-fixed frame. © 2012 American Chemical Society.

Lu J.,Jilin University | Der Steen T.V.,Mayo Medical School | Tindall D.J.,Mayo Medical School
Nature Reviews Urology | Year: 2015

Androgen receptor splice variants (AR-Vs) - which are expressed in castration-resistant prostate cancer (CRPC) cell lines and clinical samples - lack the C-terminal ligand-binding domain and are constitutively active. AR-Vs are, therefore, resistant to traditional androgen deprivation therapy (ADT). AR-Vs are induced by several mechanisms, including ADT, and might contribute to the progression of CRPC and resistance to ADT. AR-Vs could represent a novel therapeutic target for prostate cancer, especially in CRPC.

Li H.,Jilin University | Wu L.,Jilin University
Soft Matter | Year: 2014

The introduction of metal centers to a supramolecular polymer system is an important approach to fabricate hybrid supramolecular polymers with synergistic properties between their inorganic and organic components, which is mainly realized through two strategies: one is the embedment of metal ions through metal-ligand coordination to form metallo-supramolecular polymers (MSPs); the other is using metal-containing clusters as hybrid building blocks to prepare clusto-supramolecular polymers (CSPs). The available paradigms of MSPs and CSPs not only exhibit the unique functions of metal centers but also hold the good processing ability and the stimuli-responsibility of dynamically bonded polymeric structures, thus representing a new class of hybrid soft materials. In this review, the development and recent progress of MSPs and CSPs are discussed in detail, including their structure design, synthetic procedures and related properties. Finally, challenges and potential areas in metal-containing supramolecular polymers are outlooked. This journal is © the Partner Organisations 2014.

Khan M.,Jilin University
International journal of biological sciences | Year: 2012

Isoalantolactone, a sesquiterpene lactone compound possesses antifungal, antibacteria, antihelminthic and antiproliferative activities. In the present study, we found that isoalantolactone inhibits growth and induces apoptosis in pancreatic cancer cells. Further mechanistic studies revealed that induction of apoptosis is associated with increased generation of reactive oxygen species, cardiolipin oxidation, reduced mitochondrial membrane potential, release of cytochrome c and cell cycle arrest at S phase. N-Acetyl Cysteine (NAC), a specific ROS inhibitor restored cell viability and completely blocked isoalantolactone-mediated apoptosis in PANC-1 cells indicating that ROS are involved in isoalantolactone-mediated apoptosis. Western blot study showed that isoalantolactone increased the expression of phosphorylated p38 MAPK, Bax, and cleaved caspase-3 and decreased the expression of Bcl-2 in a dose-dependent manner. No change in expression of phosphorylated p38 MAPK and Bax was found when cells were treated with isoalantolactone in the presence of NAC, indicating that activation of these proteins is directly dependent on ROS generation. The present study provides evidence for the first time that isoalantolactone induces ROS-dependent apoptosis through intrinsic pathway. Furthermore, our in vivo toxicity study demonstrated that isoalantolactone did not induce any acute or chronic toxicity in liver and kidneys of CD1 mice at dose of 100 mg/kg body weight. Therefore, isoalantolactone may be a safe chemotherapeutic candidate for the treatment of human pancreatic carcinoma.

Zhang Y.-L.,Jilin University | Zhang Y.-L.,Yonsei University | Xia H.,Jilin University | Kim E.,Yonsei University | Sun H.-B.,Jilin University
Soft Matter | Year: 2012

The surface wettability control of solid materials has been considered as an essential aspect of surface chemistry. In the past decade, superhydrophobic surfaces have revealed a cornucopia of novel structural and functional properties, exhibiting considerable importance in both fundamental research and practical applications. In this review, we summarize the recent developments of superhydrophobic surfaces with unique structural and functional properties. Both the fabricative methods and the working performance of superhydrophobic surfaces with multidisciplinary functionalities including self-cleaning, icephobicity, anti-corrosion, drag reduction, transparency, anti-reflection, structural color, droplet transportation, anisotropy, oil-water separation, water supporting force, superamphiphobicity and responsive switching, have been discussed briefly. Finally, the current challenges and future prospects of this dynamic field are discussed based on our own opinion. © 2012 The Royal Society of Chemistry.

Liu Y.,Jilin University
International journal of medical sciences | Year: 2012

Splenosis is not an uncommon disease. However, it is often misdiagnosed as malignant tumors, and then the patients underwent unnecessary operations. Unfortunately, it is very difficult to diagnose it prior to operation. We report a rare case of a 49-year-old female patient with liver and colon splenosis, misdiagnosed as liver and colon tumors, and summarize experience how to diagnose it preoperatively according to literatures. We come to conclusion that in patients who ever underwent splenectomy especially owning to trauma, and were found mass in abdomen, clinicians must consider the existence of splenosis, and take some measures, such as scintigraphy with (99m) Tc labelled heat-denatured erythrocyte rather than biopsy, to diagnose it correctly to prevent unnecessary operations.

Qu L.,Jilin University | Xu W.,Jilin University
Cancer Research and Clinic | Year: 2016

Malignant colon cells require angiogenesis and optimal tumor microenvironment for proliferation, invasion and metastasis. The non-receptor tyrosine kinase signal transducer and activator of transcription (JAK-STAT) pathway are involved in multiple processes, including chronic inflammation-associated tumorigenesis, cancer proliferation, tumor angiogenesis, immune evasion and facilitating tumor metastasis, making JAK-STAT a new target in molecular target therapy. In this review, advances on JAK-STAT pathway as a new target in colon tumorigenesis are updated, and a preliminary estimation of JAK-STAT in prognosis and target therapy will be mentioned to show a potential future of JAK-STAT in colon cancer. © Copyright 2016 by the Chinese Medical Association.

Liu H.,Jilin University | Liu L.,Jilin University | Zhang H.,Northeast Normal University
Pattern Recognition | Year: 2010

Cancer diagnosis is an important emerging clinical application of microarray data. Its accurate prediction to the type or size of tumors relies on adopting powerful and reliable classification models, so as to patients can be provided with better treatment or response to therapy. However, the high dimensionality of microarray data may bring some disadvantages, such as over-fitting, poor performance and low efficiency, to traditional classification models. Thus, one of the challenging tasks in cancer diagnosis is how to identify salient expression genes from thousands of genes in microarray data that can directly contribute to the phenotype or symptom of disease. In this paper, we propose a new ensemble gene selection method (EGS) to choose multiple gene subsets for classification purpose, where the significant degree of gene is measured by conditional mutual information or its normalized form. After different gene subsets have been obtained by setting different starting points of the search procedure, they will be used to train multiple base classifiers and then aggregated into a consensus classifier by the manner of majority voting. The proposed method is compared with five popular gene selection methods on six public microarray datasets and the comparison results show that our method works well. © 2010 Elsevier Ltd. All rights reserved.

Xi G.-L.,Jilin University | Liu Z.-Q.,Jilin University
Journal of Agricultural and Food Chemistry | Year: 2015

Two coumarin skeletons can form chromeno[3,4-c]chromene-6,7-dione by sharing with the C=C in lactone. The aim of the present work was to explore the antioxidant effectiveness of the coumarin-fused coumarin via six synthetic compounds containing hydroxyl and N,N-dimethylamino as the functional groups. The abilities to quench 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonate) cationic radical (ABTS+•), 2,2′-diphenyl-1-picrylhydrazyl radical (DPPH), and galvinoxyl radical revealed that the rate constant for scavenging radicals was related to the amount of hydroxyl group in the scaffold of coumarin-fused coumarin. But coumarin-fused coumarin was able to inhibit DNA oxidations caused by •OH, Cu2+/glutathione (GSH), and 2,2′-azobis(2-amidinopropane hydrochloride) (AAPH) even in the absence of hydroxyl group. In particular, a hydroxyl and an N,N-dimethylamino group locating at different benzene rings increased the inhibitory effect of coumarin-fused coumarin on AAPH-induced oxidation of DNA about 3 times higher than a single hydroxyl group, whereas N,N-dimethylamino-substituted coumarin-fused coumarin possessed high activity toward •OH-induced oxidation of DNA without the hydroxyl group contained. Therefore, the hydroxyl group together with N,N-dimethylamino group may be a novel combination for the design of coumarin-fused heterocyclic antioxidants. © 2015 American Chemical Society.

Ma D.-L.,CAS Changchun Institute of Applied Chemistry | Ma D.-L.,Jilin University | Cao Z.-Y.,Jilin University | Wang H.-G.,CAS Changchun Institute of Applied Chemistry | And 4 more authors.
Energy and Environmental Science | Year: 2012

A new hybrid nanostructure composed of three-dimensionally ordered macroporous (3DOM) FeF 3 and an homogenous coating of poly(3, 4-ethylenedioxythiophene) (PEDOT) is successfully synthesized using polystyrene (PS) colloidal crystals as hard template, and the coating of PEDOT is achieved through a novel in situ polymerization method. The special nanostructure provides a three-dimensional, continuous, and fast electronic and ionic path in the electrode. Surprisingly, the advantageous combination of 3DOM structure and homogenous coating of PEDOT endows the as-prepared hybrid nanostructures with a stable and high reversible discharge capacity up to 210 mA h g -1 above 2.0 V at room temperature (RT), and a good rate capability of 120 mA h g -1 at a high current density of 1 A g -1, which opens up new opportunities in the development of high performance next-generation lithium-ion batteries (LIBs). © 2012 The Royal Society of Chemistry.

Zhang S.-F.,Jilin University | Chen X.-K.,Jilin University | Fan J.-X.,Jilin University | Ren A.-M.,Jilin University
Organic Electronics: physics, materials, applications | Year: 2013

The charge transport properties in a series of five-ring-fused thienoacenes are detailedly investigated here. With both high 3-D hole mobilities and good oxidative stability, the thiophene-benzene alternate structures in series B should be better than other two series as p-type organic semiconductors. In addition, a theoretical explanation for the difference between experimental hole mobilities in B-3 and B-3- is provided based on crystal structure prediction. The role of dynamic disorder in C-3 is also investigated here and the results indicate that dynamic disorder plays a crucial role both in the 1-D and 2-D carrier transporting process. © 2012 Elsevier B.V. All rights reserved.

Liu S.,Jilin University | Hu J.,Jilin University | Zhang H.,Jilin University | Su X.,Jilin University
Talanta | Year: 2012

In this paper, a sensitive and simple method for the determination of melamine (MA) was developed based on the fluorescence changes of the water-soluble CuInS2 quantum dots (QDs). The water-soluble CuInS 2 QDs capped by mercaptopropionic acid (MPA) was directly synthesized by hydrothermal method based on our previous report. The fluorescence emission of CuInS2 QDs was quenched by the oxidation of the surface of the QDs with H2O2, and the quenched fluorescence of CuInS 2 QDs could be recovered upon the addition of small amounts of MA, which might be due to the surface passivation of the CuInS2 QDs by MA. The other amino acids such as glycine and lysine had no effect on the quenched fluorescence of CuInS2 QDs. Under optimum conditions, there was a good linear relationship between the fluorescence intensity of CuInS 2 QDs and the concentration range of MA from 1.0×10 -8 to 1.0×10-5 mol/L with a detection limit as low as 5 nM. The proposed method was successfully applied to detect trace MA in raw milk with satisfactory results. Compared with previous reports, the proposed method manifested several advantages such as high sensitivity, short analysis time, low cost and ease of operation. © 2012 Elsevier B.V. All rights reserved.

Zhuang H.,Jilin University | Tang N.,Jilin University | Yuan Y.,Jilin University
Journal of Functional Foods | Year: 2013

Corn gluten meal was hydrolyzed by alkaline protease and Flavourzyme to obtain the antioxidant peptides. The antioxidant activities of the hydrolysates or peptides were evaluated by free radical scavenging capacity (1,1-diphenyl-2-picrylhydrazyl/2,2-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt/hydroxyl radical/superoxide radical anion), metal ion (Fe2+/Cu2+) chelating activity and lipid peroxidation inhibitory capacity. The hydrolysates were separated by ultrafiltration, and those with molecular weight <10kDa exhibited highest antioxidant activity in all relevant assays. The hydrolysates were subsequently purified by gel filtration chromatography, and fraction F3 showed the highest antioxidant activity. Three peptides were identified from fraction F3 using LC-ESI-Q-TOF MS/MS as Leu-Pro-Phe (375.46Da), Leu-Leu-Pro-Phe (488.64Da) and Phe-Leu-Pro-Phe (522.64Da). These peptides exhibited good free radical scavenging activity and lipid peroxidation inhibitory effect. Thus, corn gluten meal may be used as a potential source of antioxidant peptides for food and nutraceutical applications. © 2013 Elsevier Ltd.

Ren W.,Jilin University | Gu G.,Jilin University
European Journal of Cancer Care | Year: 2015

Primary osteosarcoma is the most frequent malignant bone cancer in children and teenagers. Genetic alterations at the retinoblastoma 1 (RB1) gene has been implicated in the development and progression of human osteosarcoma. Here, we performed a meta-analysis to examine the impact of RB1 mutations on the survival of osteosarcoma patients, the risk of metastasis and the histological response of osteosarcoma to chemotherapy. A systemic review of the Medline, Embase, Scopus and Cochrane Library yielded 12 eligible studies with 491 patients for this study. Forest plots resulting from our meta-analyses illustrate that loss of RB1 function results in a 1.62-fold increase in the mortality rate for osteosarcoma patients (RR = 1.62, 95% CI: 1.23-2.13; Z = 3.44, P = 0.0006), a significant increase in osteosarcoma metastasis (OR = 3.95, 95% CI: 1.86-8.38; Z = 3.57; P = 0.0004), and a significant reduction in the histological response of osteosarcoma to chemotherapy (OR = 0.35; 95% CI: 0.13-0.94; Z = -2.08; P = 0.038). Additionally, the nearly symmetrical funnel plot (Egger's test, t = 1.15, P = 0.288) indicates absence of publication bias regarding the meta-analysis that examined the correlation of RB1 alterations with the survival rate for osteosarcoma patients. Our findings suggest that RB1 alterations may serve as a prognostic marker for the management of osteosarcoma patients. © 2015 John Wiley & Sons Ltd.

Zhou J.-B.,Jilin University | Zhou J.-B.,Curtin University Australia | Wilde S.A.,Jilin University | Wilde S.A.,Curtin University Australia
Gondwana Research | Year: 2013

The basement rocks in parts of NE China constitute a khondalitic sequence of sillimanite- and garnet-bearing gneisses, hornblende-plagioclase gneiss and various felsic paragneisses. Zircon U-Pb dating of garnet-sillimanite gneiss samples from the Erguna, Xing'an, Jiamusi and Khanka blocks indicates that high-grade metamorphism occurred at ~ 500. Ma. Evidence from detrital zircons in Paleozoic sediments from the Songliao Block also indicates the former presence of a ~ 500. Ma component. This uniformity of U-Pb ages across all crustal blocks in NE China establishes a >. 1300. km long Late Pan-African khondalite belt which we have named the 'NE China Khondalite Belt'. This indicates the blocks of NE China were amalgamated prior to ~ 500. Ma, contrary to current belief. One scenario is that this amalgamated terrane had a tectonic affinity to the Siberia Craton, once forming part of the Late Pan-African (~ 500. Ma) Sayang-Baikal orogenic belt extensively developed around the southern margin of the Siberia Craton. This belt was the result of collision between currently unidentified terranes with the Southeastern Angara-Anabar Province at about 500. Ma, where the rocks were deformed and metamorphosed to granulite facies. It appears likely that at sometime after ~ 450. Ma, the combined NE China blocks rifted away from Siberia and moved southward to form what is now NE China. The combined block collided with the North China Craton along the Solonker-Xar Moron-Changchun suture zone at ~ 230. Ma rather than in the end-Permian as previously thought. Local rifting at the eastern extremity of the developing Central Asian Orogenic Belt (CAOB) resulted in the splitting away of the Jiamusi/Khanka(/Bureya) blocks. However, this was only transient and sometime between 210 and 180. Ma, these were re-united with the CAOB by the onset of Pacific plate subduction, which has dominated the tectonic evolution of the region since that time. © 2012 International Association for Gondwana Research.

Liu Y.,Jilin University | Liu Y.,University of Texas at Austin | Fomel S.,University of Texas at Austin
Geophysical Prospecting | Year: 2013

Many natural phenomena, including geologic events and geophysical data, are fundamentally nonstationary - exhibiting statistical variation that changes in space and time. Time-frequency characterization is useful for analysing such data, seismic traces in particular. We present a novel time-frequency decomposition, which aims at depicting the nonstationary character of seismic data. The proposed decomposition uses a Fourier basis to match the target signal using regularized least-squares inversion. The decomposition is invertible, which makes it suitable for analysing nonstationary data. The proposed method can provide more flexible time-frequency representation than the classical S transform. Results of applying the method to both synthetic and field data examples demonstrate that the local time-frequency decomposition can characterize nonstationary variation of seismic data and be used in practical applications, such as seismic ground-roll noise attenuation and multicomponent data registration. © 2012 European Association of Geoscientists & Engineers.

Lai H.-W.,Jilin University | Liu Z.-Q.,Jilin University
European Journal of Medicinal Chemistry | Year: 2014

4-Thiaflavan is a sulfur-substituted flavonoid with a benzoxathiin scaffold. The aim of this work is to compare abilities of sulfur and oxygen atom, hydroxyl groups, and ferrocene moiety at different positions of 4-thiaflavan to trap radicals and to inhibit DNA oxidation. It is found that abilities of thiaflavans to trap radicals and to inhibit DNA oxidation are increased in the presence of ferrocene moiety and are further improved by the electron-donating group attaching to thiaflavan skeleton. It can be concluded that the ferrocene moiety plays the major role for thiaflavans to be antioxidants even in the absence of phenolic hydroxyl groups. On the other hand, the antioxidant effectiveness of phenolic hydroxyl groups in thiaflavans can be improved by the electron-donating group. The influences of sulfur and oxygen atoms in thiaflavans on the antioxidant property of para-hydroxyl group exhibit different manners when the thiaflavans are used to trap radicals and to inhibit DNA oxidation. © 2014 Elsevier Masson SAS. All rights reserved.

Xi G.-L.,Jilin University | Liu Z.-Q.,Jilin University
European Journal of Medicinal Chemistry | Year: 2014

Twenty-two 2-phenyl-4-ferrocenylquinolines are synthesized by Povarov three-component-reaction (3CR) among the substituted anilines, benzaldehydes, and ferrocenylacetylene with Ce(OTf)3 being catalyst in the absence of solvents. The antioxidative effects of the obtained quinolines are estimated by quenching 2,2€2-azinobis(3-ethylbenzothiazoline-6-sulfonate) cationic radical (ABTS+), 2,2#x020AC;2-diphenyl-1-picrylhydrazyl (DPPH), and galvinoxyl radicals, and by inhibiting Cu2+/glutathione (GSH)-, hydroxyl radical (OH)-, and 2,2#x020AC;2-azobis(2-amidinopropane hydrochloride) (AAPH)-induced oxidations of DNA. It is found that the ferrocenyl group instead of hydroxyl group generates the antioxidative effect for quinoline to quench radicals and to protect DNA against radical-induced oxidations. The antioxidative effect generated by ferrocenyl group can be further increased by the electron-donating moieties such as furan, -N(CH3)2, -OCH3, and ferrocenyl group, while the electron-withdrawing groups such as -NO2 and -Cl are not beneficial for quinolines to be antioxidants. The ferrocenyl group in quinoline exhibits higher antioxidant activity than hydroxyl group in Trolox. © 2014 Elsevier Masson SAS.

Chen H.-L.,Jilin University | Yang B.,Jilin University | Liu J.,Jilin University | Liu D.-Y.,Jilin University
Expert Systems with Applications | Year: 2011

Breast cancer is becoming a leading cause of death among women in the whole world, meanwhile, it is confirmed that the early detection and accurate diagnosis of this disease can ensure a long survival of the patients. Expert systems and machine learning techniques are gaining popularity in this field because of the effective classification and high diagnostic capability. In this paper, a rough set (RS) based supporting vector machine classifier (RS-SVM) is proposed for breast cancer diagnosis. In the proposed method (RS-SVM), RS reduction algorithm is employed as a feature selection tool to remove the redundant features and further improve the diagnostic accuracy by SVM. The effectiveness of the RS-SVM is examined on Wisconsin Breast Cancer Dataset (WBCD) using classification accuracy, sensitivity, specificity, confusion matrix and receiver operating characteristic (ROC) curves. Experimental results demonstrate the proposed RS-SVM can not only achieve very high classification accuracy but also detect a combination of five informative features, which can give an important clue to the physicians for breast diagnosis. © 2011 Elsevier Ltd. All rights reserved.

The important differences in physiological parameters and anatomical characteristics of the kidney between humans and mice make it difficult to replicate the precise progression of human renal cystic diseases in gene modification mouse models. In contrast to mice, pigs are a better animal model of human diseases, as they are more similar in terms of organ size, structure, and physiological parameters. Here, we report the generation and initial examination of an AQP2-Cre transgenic (Tg) Chinese miniature (mini)-pig line that expresses Cre recombinase exclusively in kidney collecting duct cells. An 8-kb fragment of the mini-pig aquaporin 2 (AQP2) 5'-flanking region was utilized to direct Cre expression in Tg mini-pigs. Two Tg mini-pigs were generated by pig somatic cell nuclear transfer and both carried the entire coding sequence of Cre recombinase. RT-PCR and western blotting analysis revealed that Cre recombinase was uniquely expressed in the kidney, while immunohistochemical studies located its expression in kidney collecting duct cells. Furthermore, six integration sites and 12-14 copies of the Cre gene were detected in various tissues by high-efficiency thermal asymmetric interlaced PCR and absolute quantitative real-time PCR, respectively. Combined with previous studies of Cre recombinase activity, we believe that this AQP2-Cre Tg mini-pig line will be a useful tool to generate kidney collecting duct cell-specific gene knockout mini-pig models, thereby allowing the investigation of gene functions in kidney development and the mechanisms of human renal cystic disease.

Sun Y.-L.,Jilin University | Liu D.X.,Jilin University | Dong W.-F.,Jilin University | Chen Q.D.,Jilin University | Sun H.B.,Jilin University
Optics Letters | Year: 2012

Herein, tunable protein harmonic diffractive microlenses (PHDMs) have been constructed by femtosecond laser direct writing from bovine serum albumin. With excellent three-dimensional topography, PHDMs show distinct harmonic diffractive features, such as similarly good imaging performance with smaller thickness than refractive lenses and well controlled minus chromatic dispersion compared with simple diffractive lenses (∼5% focal length shift against ∼21% of the protein Fresnel zone plate with the same radius under light with wavelength 450-659 nm). Owing to the nature of protein molecules as "building blocks," the focal length of the PHDM can be facilely tuned within seconds by changing the pH value (focal length tunability of up to ∼20%). © 2012 Optical Society of America.

Peng F.,Jilin University | Peng F.,Luoyang Normal University | Miao M.,University of California at Santa Barbara | Wang H.,Jilin University | And 2 more authors.
Journal of the American Chemical Society | Year: 2012

High pressure can fundamentally alter the bonding patterns of light elements and their compounds, leading to the unexpected formation of materials with unusual chemical and physical properties. Using an unbiased structure search method based on particle-swarm optimization algorithms in combination with density functional theory calculations, we investigate the phase stabilities and structural changes of various Li-B systems on the Li-rich regime under high pressures. We identify the formation of four stoichiometric lithium borides (Li3B2, Li2B, Li4B, and Li6B) having unforeseen structural features that might be experimentally synthesizable over a wide range of pressures. Strikingly, it is found that the B-B bonding patterns of these lithium borides evolve from graphite-like sheets in turn to zigzag chains, dimers, and eventually isolated B ions with increasing Li content. These intriguing B-B bonding features are chemically rationalized by the elevated B anionic charges as a result of LiB charge transfer. © 2012 American Chemical Society.

The layer-by-layer (LbL) codeposition of polyelectrolyte-polyelectrolyte complexes (PECs) and free polyelectrolytes with oppositely charged polyelectrolytes for the fabrication of polymeric films has been systematically investigated. Aqueous dispersions containing positively charged diazoresin (DAR)poly(acrylic acid) (PAA) complexes (denoted as DAR-PAA) and free DAR were used as the dipping solutions for LbL film fabrication with PAA. Simultaneous deposition of DAR-PAA complexes and free DAR with PAA took place under a nondrying LbL deposition process that produced bilayered thick polymeric films with the hierarchical PAA/DAR-PAA coatings rooting in the underlying continuous PAA/DAR films. The structure of the bilayered polymeric films depends largely on the ratio of DAR-PAA complexes to free DAR in the dipping solution. The more rapid deposition of PAA/DAR-PAA coatings than that of the PAA/DAR films accounts for the formation of bilayered polymeric films because DAR-PAA complexes have larger dimensions than DAR in solution. The bilayered polymeric coatings with hierarchical structures rooting in continuous films have enhanced adhesion with the underlying substrates because of the increased contacting area. After chemical vapor deposition of a layer of fluoroalkylsilane, the bilayered polymeric coatings can be easily converted into superhydrophobic. In contrast, the LbL codeposition of DAR-PAA complexes and DAR with PAA produces thin and compact films without bilayered structures when a N2 drying step is conducted after each layer deposition. The present study is meaningful in deeply understanding the deposition behavior and structure tailor of LbL assembled films using PECs as building blocks. © 2010 American Chemical Society.

Zhang Z.,Baicheng Normal College | Zhang Z.,Jilin University
Inorganic Chemistry Communications | Year: 2012

Silver atoms and strongly interlinking α-metatungstate units ensure the 3D structure of (NH 4) 5[Ag 5(L) 2(H 2O) 8(H 2W 12O 40)]•H 2O (L = pyridine-3,5-dicarboxylate dianion), which has been synthesized in aqueous solution and characterized by the normal physical methods as well as the single-crystal X-ray diffraction. This compound represents the first example that the α-metatungstate cluster as the structural motif is linked by transition metal complexes to yield unprecedented 3D framework with the highest eleven-connected number. © 2011 Elsevier B.V. All rights reserved.

Zhao K.,Jilin University
Proceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014 | Year: 2014

Hexavalent chromium Cr(VI) has been widely used in metal pickling and plating, which induces cancer and coetaneous allergy in the long time exposure. In this work, a novel thin film composite hollow fiber nanofiltration (NF) membrane was developed, which was optimized by time of interfacial polymerization, concentration of monomers and the IP process. In addition, operational conditions, including PH values, temperatures and operational pressures on the NF performance was further investigated to exhibit potential application in the industrial wastewater treatment and obtained resultant water for biomedical use. © 2014 IEEE.

Hou G.,Jilin University | Bi L.,Jilin University | Li B.,Jilin University | Wu L.,Jilin University
Inorganic Chemistry | Year: 2010

To investigate the influence of reaction conditions on the compound structures, five polyoxometalate (POM)-supported Inorganic-organic hybrid compounds, [Cul 3(L1)4][PW 12O40] (1). [Cul 3(L 1)4][PMO12O40] (2), [Cu l 3(L1)4][PW12O 40] (3), [Cul 3(L1) 3][PW12O40] (4), and [Cu3(L 2)3][PMO12O40] (5) [L1 = 1,4-bis(pyrazol-1-ylmethyl)benzene, L2 = 4,4′bis(pyrazol-1 -ylmethyl)biphenyl], were hydrothermally synthesized by tuning the reactant species and molar ratio and reaction temperature and were characterized by elemental analysis, IR spectroscopy, PXRD, XPS, electrochemistry. SPS, and X-ray crystallography. Compounds 1 and 2 were synthesized in the isostructural state at 150°C, In which L1 ligands link Cul ions, generating a catlonic 2D 63 (hcb) skeleton {[Cu3(L 1)4]3+}n-like sheet that further connects with POM anions, forming a neutral 2D (3,4)-connected network with a Schläfli symbol of (53)2(54;8 2). In contrast, compound 3 was synthesized at a relatively lower reaction temperature (130°C) than that for the synthesis of 1 and 2, which exhibits a similar 2D sheet-like cationic skeleton with 1 and 2. Interestingly, the POM anions do not coordinate with the cationic moieties in 3. Compounds 4 and 5 were synthesized with a relatively lower reactant molar ratio In comparison with that for the synthesis of 1-3, In which the cationic coordination moieties all present 1D chain-like structures. Compound 4 exhibits a 3D (3,4)-connected sqc74 framework with a Schläfli symbol of (6;8 2)(64;8;10) formed by the POM anions linking {[Cu 3(L1)3]3+}n cationic chains. In comparison to 4, compound 5 shows a 3D supramolecular framework,.which is formed by POM anions and {[Cu3(L 2)3]3+}n catlonic chains via hydrogen bonds. The structural difference of compounds 1-5 indicates that the reaction conditions perform a crucial Influence on the structures of this series. The electrochemical properties of 2 and 5 and the SPS responses of 3-5 suggest that these compounds can be used as potential electrocatalytic or photocatalytic framework materials. In addition, EFISPS curves Indicate that 3-5 possess the n-type semiconductor characteristic. © 2010 American Chemical Society.

Zhang H.,Jilin University | Wei A.,Jilin University | Qiu X.,Jilin University | Chen J.,Sanyou Automobile Parts Manufacturing Co.
Materials and Design | Year: 2014

In this study, resistance spot welding (RSW) experiments were performed in order to evaluate the microstructure and mechanical properties of single-lap joints between DP780 and DP600. The results show that the weld joints consist of three regions including base metal (BM), heat affected zone (HAZ) and fusion zone (FZ). The grain size and martensite volume fractions increase in the order of BM, HAZ and FZ. The hardness in the FZ is significantly higher than hardness of base metals. Tensile properties of the joints were described in terms of the failure modes and static load-carrying capabilities. Two distinct failure modes were observed during the tensile shear test of the joints: interfacial failure (IF) and pullout failure (PF). The FZ size plays a dominate role in failure modes of the joints. © 2013 Elsevier Ltd.

Li B.,University of South Florida | Zhang Y.,University of South Florida | Ma D.,Jilin University | Ma T.,Jilin Agricultural University | And 2 more authors.
Journal of the American Chemical Society | Year: 2014

In this work, a new strategy is developed to encapsulate a metal-functionalized guest molecule into a metal-organic framework (MOF) via metal-cation-directed de novo assembly from the component fragments of the guest molecule. This strategy, as illustrated in proof-of-principle studies on the de novo assembly of metal(II) phthalocyanine molecules into bio-MOF-1, can circumvent some drawbacks of existing approaches for encapsulating guest molecules into MOFs, such as inaccessibility for larger guest molecules due to limitations of the MOF window size and disruption of the MOF framework structure by functionalized guest molecules. Overall, this work provides a general yet versatile approach for encapsulating a broader range of metal-functionalized guest molecules into MOFs for various applications. © 2014 American Chemical Society.

Liu Y.,University of Maryland University College | Li Y.,Jilin University | He J.,University of Maryland University College | Duelge K.J.,University of Maryland University College | And 2 more authors.
Journal of the American Chemical Society | Year: 2014

Although an analogy has been drawn between them, organic molecular amphiphiles (MAMs) and inorganic nanoparticle (NP) amphiphiles (NPAMs) are significantly different in dimension, geometry, and composition as well as their assembly behavior. Their concurrent assembly can synergetically combine the inherent properties of both building blocks, thus leading to new hybrid materials with increasing complexity and functionality. Here we present a new strategy to fabricate hybrid vesicles with well-defined shape, morphology, and surface pattern by coassembling MAMs of block copolymers (BCPs) and NPAMs comprising inorganic NPs tethered with amphiphilic BCPs. The assembly of binary mixtures generated unique hybrid Janus-like vesicles with different shapes, patchy vesicles, and heterogeneous vesicles. Our experimental and computational studies indicate that the different nanostructures arise from the delicate interplay between the dimension mismatch of the two types of amphiphiles, the entanglement of polymer chains, and the mobility of NPAMs. In addition, the entropic attraction between NPAMs plays a dominant role in controlling the lateral phase separation of the two types of amphiphiles in the membranes. The ability to utilize multiple distinct amphiphiles to construct discrete assemblies represents a promising step in the self-assembly of structurally complex functional materials. © 2014 American Chemical Society.

Van Humbeck J.F.,University of California at Berkeley | McDonald T.M.,University of California at Berkeley | Jing X.,Jilin University | Wiers B.M.,University of California at Berkeley | And 3 more authors.
Journal of the American Chemical Society | Year: 2014

The elimination of specific environmental and industrial contaminants, which are hazardous at only part per million to part per billion concentrations, poses a significant technological challenge. Adsorptive materials designed for such processes must be engendered with an exceptionally high enthalpy of adsorption for the analyte of interest. Rather than relying on a single strong interaction, the use of multiple chemical interactions is an emerging strategy for achieving this requisite physical parameter. Herein, we describe an efficient, catalytic synthesis of diamondoid porous organic polymers densely functionalized with carboxylic acids. Physical parameters such as pore size distribution, application of these materials to low-pressure ammonia adsorption, and comparison with analogous materials featuring functional groups of varying acidity are presented. In particular, BPP-5, which features a multiply interpenetrated structure dominated by <6 Å pores, is shown to exhibit an uptake of 17.7 mmol/g at 1 bar, the highest capacity yet demonstrated for a readily recyclable material. A complementary framework, BPP-7, features slightly larger pore sizes, and the resulting improvement in uptake kinetics allows for efficient adsorption at low pressure (3.15 mmol/g at 480 ppm). Overall, the data strongly suggest that the spatial arrangement of acidic sites allows for cooperative behavior, which leads to enhanced NH3 adsorption. © 2014 American Chemical Society.

Liu D.-R.,Jilin University | Jiang Y.-S.,Jilin University | Gao G.-M.,Jilin University
Chemosphere | Year: 2011

N-doped NaTaO 3 compounds (NaTaO 3-xN x) with nano-cubic morphology were successfully synthesized by one-step hydrothermal method and Methyl Orange (MO) was used as a model dye to evaluate their photocatalytic efficiency under visible-light irradiation. The as-prepared NaTaO 3-xN x samples were characterized by various techniques, such as X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) and UV-vis diffuse reflectance spectra and GC-MS. The results indicate that NaTaO 3-xN x displays a pure perovskite structure when the synthesis temperature is higher than 180°C. Moreover, as observed by SEM images, the particles of resultant NaTaO 3-xN x show cubic morphology with the edge length of 200-500nm, which can be easily removed by filtration after photocatalytic reaction. Doping of N increases the photocatalytic activity of NaTaO 3, and NaTaO 2.953N 0.047 shows the highest visible-light photocatalytic activity for the degradation of MO. Based on the experiment results, a possible mechanism of the photocatalysis over NaTaO 3-xN x and the photodegradation pathway of MO were proposed. © 2011 Elsevier Ltd.

Hou N.,Jilin University | Wu D.,Jilin University | Li Y.,Jilin University | Li Z.-R.,Jilin University
Journal of the American Chemical Society | Year: 2014

A new kind of cationic superatom compounds (M-F)+ (M = OLi 4, NLi5, CLi6, BLi7, and Al 14) with low vertical electron affinities (VEA) has been designed based on the distinctive electronic structure of superalkaline-earth atom. The stability of the studied superatom architectures is guaranteed by strong M-fluorine interactions, considerable HOMO-LUMO gaps, as well as large dissociation energies. What is extraordinary is that fluorination plays an important role in lowering the VEA value of M+ and enables the resulting (M-F)+ fluorides to join the superalkali family. However, the same strategy does not work as well for the alkaline-earth atoms whose valence electrons are more tightly bound. The comparative study on (OLi 4-X)+ (X = F, Cl, Br) reveals that fluorination is more effective than chlorination and bromination to reduce the VEA value of the OLi4+ cation. As for the (Al14-X)+ species, there is no obvious dependence of VEA values on halogen atomic number. © 2014 American Chemical Society.

Ge X.-L.,Jilin University | Du H.,Jilin University | Guo J.,Jilin University | Liu X.-S.,Jilin University
Optics Express | Year: 2015

By solving a two-dimensional time-dependent Schrödinger equation we investigate high harmonic generation (HHG) and isolated attosecond pulse generation for the H2+ molecular ion in a circularly polarized laser pulse combined with a Terahertz (THz) field. The harmonic intensity can be greatly enhanced and a continuum spectrum can be obtained when a THz field is added. The HHG process is studied by the semi-classical threestep model and the time-frequency analysis. Our studies show that only short trajectories contribute to HHG. Furthermore, we present the temporal evolution of the probability density of electron wave packet, which perfectly shows a clear picture of the electron's two-time recombination when a THz field is added, and it is the main mechanism of HHG. By superposing the harmonics in the range of 216-249 eV, an isolated attosecond pulse with a duration of about 69 attoseconds can be generated. © 2015 Optical Society of America.

Nie H.,Jilin University | Zhao Y.,Jilin University | Zhang M.,Jilin University | Ma Y.,Jilin University | And 2 more authors.
Chemical Communications | Year: 2011

A novel fluorescent poly(2,7-carbazole) with a 4-[tris-(4-octyloxyphenyl) methyl]phenyl side chain is used to detect the explosive compounds TNT and DNT. It shows high recycled fluorescence quenching sensitivity, which is due to its strong electron donating ability and weaker interaction between the polymer chains caused by the bulky side chain. © 2011 The Royal Society of Chemistry.

Meng L.,Jilin University | Chen D.,Jilin University | Yang Y.,Jilin University | Zheng Y.,Jilin University | Hui R.,Chinese Academy of Sciences
Journal of Hypertension | Year: 2012

Background: It has long been known that depression is associated with hypertension but whether depression is a risk factor for hypertension incidence is still inconclusive. Objectives: To assess whether depression increases the incidence of hypertension. METHOD:: Literatures were searched from PubMed, EMBASE, Cochrane and PsycINFO without language restrictions. Any prospective cohort study was included, which reported the correlation between depression and incidence of hypertension in apparently healthy normotensive individuals. At baseline, the studies which had at least one self-report or interview-based assessment on depressive symptoms/disorders were selected. The definition of hypertension was defined as a repeatedly elevated blood pressure exceeding 140 (systolic) and/or over 90 mmHg (diastolic) determined in interview, use of antihypertensive medications, or self-reported or recorded diagnosed hypertension. Studies with cross-sectional or case-control design were excluded. Data abstraction was conducted independently by two authors. Results: Seventy-five full texts were initially searched, but only nine studies met our inclusion criteria, and they were comprised of 22 367 participants with a mean follow-up period of 9.6 years. We found that depression increased the risk of hypertension incidence [adjusted relative risk 1.42, 95% confidence interval (CI) 1.09 to 1.86, P = 0.009] and the risk was significantly correlated with the length of follow-up (P = 0.0002) and the prevalence of depression at baseline (P < 0.0001). Conclusions: Our meta-analysis supports that depression is probably an independent risk factor of hypertension. It is important to take depression into consideration during the process of prevention and treatment of hypertension. Further studies are needed to exclude the effects of other confounding factors. © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins.

Cisplatin resistance is a difficult problem in clinical chemotherapy, and the mechanisms involved in cisplatin resistance require further study. In this study, we investigated the role of chloride channel-3 (ClC-3) in cisplatin resistance. Autophagy was demonstrated by accumulation of LC3-II, beclin 1 and Atg12-Atg5. The ultrastructure changes were observed under electron microscope. Chemical staining with acridine orange or MDC was used to detect acidic vesicular organelles. Quantification of apoptosis was detected by PI and Annexin V staining. The mechanisms involved in the Akt pathway and autophagy were studied by western blot analysis. Our results showed that Akt phosphorylation and autophagy were induced by cisplatin in human glioma U251 cells. Specific inhibition of ClC-3 by ClC-3 siRNA sensitized the apoptosis-resistant U251 cells to cisplatin-mediated cell death and downregulated phosphorylated Akt. Interestingly, ClC-3 suppression also inhibited induction of autophagy by cisplatin although the Akt/mTOR pathway was deregulated. Counteracting the autophagic process by 3-methylademine enhanced cytotoxicity of cisplatin, revealing that autophagy plays a key role in chemoresistance. Suppressing the Akt/mTOR pathway by the NADPH oxidase inhibitor diphenyl iodonium (DPI) indicated that cisplatin-induced activation of Akt/mTOR pathway requires generation of reactive oxygen species (ROS) through NADPH oxidase. Collectively, our results suggest that ClC-3 suppression causes the inhibition of Akt and autophagy, which can enhance the therapeutic benefit of cisplatin in U251 cells. Copyright © 2013 Wiley Periodicals, Inc.

Li C.,Jilin University | Zhou X.,Jilin University
Clinica Chimica Acta | Year: 2012

The presence of a complex population of gene transcripts in mature human sperm is well established, and numerous mRNAs and non-coding mRNAs have been identified in sperm of men and other mammalian species using microarray and RT-PCR. The traditional concept that RNAs in mature sperm are only remnants from spermatogenesis and have no biological functions is in doubt. The findings that reverse transcriptases in sperm are active and that sperm can independently activate translation of stored mRNAs suggest that sperm RNAs may have significant effects on male fertility. The differences in expression profiles among RNAs in mature sperm from fertile and infertile men, and the regulation of sperm RNAs in embryonic development make them appealing markers for therapeutic and diagnostic tools in male infertility. In this review, methods for the detection and description of the diversity of gene transcript in sperm are discussed along with their putative roles in functional aspects of sperm and in embryogenesis. © 2012 Elsevier B.V.

Tang G.,Jilin University | Du L.,Jilin University | Su X.,Jilin University
Food Chemistry | Year: 2013

In this paper, we constructed the fluorescence resonance energy transfer (FRET) system between MPAcapped CdTe quantum dots (QDs) and Rhodamine B (RB) in the environment of cetyltrimethylammonium bromide (CTAB). In this system, CdTe QDs were treated as energy donors, whilst RB was treated as energy acceptor. CTAB was used to make the distance between the particles of CdTe QDs and RB closer to improve the efficiency of FRET system. We optimized some important factors which would affect the efficiency of FRET system. Under the optimized experimental conditions, melamine (MB) could be detected based on the fluorescence intensity changes of RB in the FRET system. We could get a linear relationship between the fluorescence intensity of RB and the concentration of MB in the range of 0.05-4.0 μmol/L and the detection limit was 0.01 μmol/L. The proposed method was applied for the determination of melamine in milk samples with satisfactory results. © 2013 Elsevier Ltd.

Li M.,Jilin University
Environmental technology | Year: 2011

The reductive degradation of nitrobenzene (NB) by iron-carbon micro-electrolysis packing was investigated. The influence of initial NB concentration, pH value and packing amount on the removal rate of NB were studied. The results showed that the reaction with packing followed the pseudo-first-order reaction. The optimum pH was 3.0 for the degradation of NB in the tested pH ranges of 3-9 and the optimum packing amount was 40 g/200 ml. The flow-through column packed with packing was designed to remove NB from simulated wastewater for approximately 68 days. The removal rate was over 90% within initial periods. It could be seen that after running for 68 days, the packing still had good performance after the long-term column experiment. In addition, the changes of the packing surfaces morphologies and matters before, during and after the column experiment were analysed by scanning electron microscopy in conjunction with energy-dispersion spectroscopy (EDS).

Cui Z.-H.,Jilin University | Contreras M.,University of Guanajuato | Ding Y.-H.,Jilin University | Merino G.,University of Guanajuato
Journal of the American Chemical Society | Year: 2011

In this study, we analyzed CB4 and its cation, CB 4 +. Using CCSD(T)/aug-cc-pVQZ//CCSD(T)/aug-cc-pVTZ quantum-chemical calculations, we found that the neutral molecule is in accord with the results of Boldyrev and Wang, having a Cs global minimum with a planar tricoordinate carbon structure, contradicting previous studies. In contrast, CB4 +, which was reported by an early mass spectroscopic study, has a planar tetracoordinate carbon (ptC) atom, demonstrating that a modification of the charge can promote the stabilization of a ptC structure. © 2011 American Chemical Society.

Gao P.,Jilin University
IMA Journal of Mathematical Control and Information | Year: 2016

This paper is concerned with the optimal distributed control problem of the Kuramoto-Sivashinsky equation with pointwise state constraints and coupled integral state-control constraints. Based on perturbation methods of modern variational analysis and Ekeland's variational principle, the Pontryagin's minimum principle of this system is proved. The main difficulty in this paper is to deal with the non-linear term in the Kuramoto-Sivashinsky equation. © The Authors 2015. Published by Oxford University Press on behalf of the Institute of Mathematics and its Applications. All rights reserved.

Li Q.,Jilin University | Li Q.,University of Nevada, Las Vegas | Zhou D.,Jilin University | Zhou D.,University of Nevada, Las Vegas | And 3 more authors.
Physical Review Letters | Year: 2013

Tungsten borides are among a distinct class of transition-metal light-element compounds with superior mechanical properties that rival those of traditional superhard materials. An in-depth understanding of these compounds, however, has been impeded by uncertainties regarding their complex crystal structures. Here, we examine a wide range of chemical compositions of tungsten borides using a recently developed global structural optimization approach. We establish thermodynamically stable structures and identify a large number of metastable phases. These results clarify and correct previous structural assignments and predict new structures for possible synthesis. Our findings provide crucial insights for understanding the rich and complex crystal structures of tungsten borides, which have broad implications for further exploration of this class of promising materials. © 2013 American Physical Society.

Liu S.,Jilin University | Zhang H.,Jilin University | Qiao Y.,Jilin University | Su X.,Jilin University
RSC Advances | Year: 2012

In this paper, we present a novel and simple hydrothermal synthesis method for preparing water soluble high quality ternary CuInS 2 quantum dots (QDs) with mercaptopropionic acid (MPA) as the stabilizer. The influences of various experimental variables, including the precursor concentrations, reaction time, reaction temperature, pH value, the MPA/Cu molar ratio, as well as the kind of capping ligand used on the luminescent properties of the obtained ternary CuInS 2 QDs have been systematically investigated. The stable ternary CuInS 2 QDs with good photoluminescence emission properties and narrow size distribution can be obtained under optimum experimental conditions. It was used to label liver cancer cells. The optical features and structure of the obtained CuInS 2 QDs have been characterized by UV-vis and fluorescence spectroscopy, TEM, XRD, FT-IR and EDX. The proposed synthesis method was simple, low cost, with comparatively low reaction temperature (150 °C), and the as-synthesized near-infrared CuInS 2 QDs was proven to have excellent photostability. The synthesized CuInS 2 QDs is a promising fluorescent probe for biological and biomedical imaging due to its bandgap in the near infrared and the absence of toxic heavy metal ions. © 2012 The Royal Society of Chemistry.

Liu H.,Jilin University | Ma Y.,Jilin University
Physical Review Letters | Year: 2013

The recent discovery of phase IV of solid hydrogen and deuterium consisting of two alternate layers of graphenelike three-molecule rings and unbound H 2 molecules have generated great interest. However, the vibrational nature of phase IV remains poorly understood. Here, we report a peculiar proton or deuteron transfer and a simultaneous rotation of three-molecule rings in graphenelike layers predicted by ab initio variable-cell molecular dynamics simulations for phase IV of solid hydrogen and deuterium at pressure ranges of 250-350 GPa and temperature range of 300-500 K. This proton or deuteron transfer is intimately related to the particular elongation of molecules in graphenelike layers, and it becomes more pronounced with increasing pressure at the course of larger elongation of molecules. As the consequence of proton transfer, hydrogen molecules in graphenelike layers are short lived and hydrogen vibration is strongly anharmonic. Our findings provide direct explanations on the observed abrupt increase of Raman width at the formation of phase IV and its large increase with pressure. © 2013 American Physical Society.

Luo W.,Fudan University | Ma Y.,Jilin University | Gong X.,Fudan University | Xiang H.,Fudan University
Journal of the American Chemical Society | Year: 2014

A method based on the particle swarm optimization algorithm is presented to design quasi-two-dimensional materials. With this development, various single-layer and bilayer materials of C, Si, Ge, Sn, and Pb were predicted. A new Si bilayer structure is found to have a more favored energy than the previously widely accepted configuration. Both single-layer and bilayer Si materials have small band gaps, limiting their usages in optoelectronic applications. Hydrogenation has therefore been used to tune the electronic and optical properties of Si layers. We discover two hydrogenated materials of layered Si8H2 and Si6H2 possessing quasidirect band gaps of 0.75 and 1.59 eV, respectively. Their potential applications for light-emitting diode and photovoltaics are proposed and discussed. Our study opened up the possibility of hydrogenated Si layered materials as next-generation optoelectronic devices. © 2014 American Chemical Society.

Vantomme G.,CNRS Institute of Science and Supramolecular Engineering | Jiang S.,CNRS Institute of Science and Supramolecular Engineering | Jiang S.,Jilin University | Lehn J.-M.,CNRS Institute of Science and Supramolecular Engineering
Journal of the American Chemical Society | Year: 2014

Constitutional dynamic libraries of hydrazones aAbB and acylhydrazones aAcC undergo reorganization and adaptation in response to a chemical effector (metal cations) or a physical stimulus (light). The set of hydrazones [1A1B, 1A2B, 2A1B, 2A 2B] undergoes metalloselection on addition of zinc cations which drive the amplification of Zn(1A2B)2 by selection of the fittest component 1A2B. The set of acylhydrazones [E-1A1C, 1A2C, 2A1C, 2A2C] undergoes photoselection by irradiation of the system, which causes photoisomerization of E- 1A1C into Z-1A1C with amplification of the latter. The set of acyl hydrazones [E-1A1C, 1A3C, 2A1C, 2A 3C] undergoes a dual adaptation via component exchange and selection in response to two orthogonal external agents: a chemical effector, metal cations, and a physical stimulus, light irradiation. Metalloselection takes place on addition of zinc cations which drive the amplification of Zn( 1A3C)2 by selection of the fittest constituent 1A3C. Photoselection is obtained on irradiation of the acylhydrazones that leads to photoisomerization from E-1A 1C to Z-1A1C configuration with amplification of the latter. These changes may be represented by square constitutional dynamic networks that display up-regulation of the pairs of agonists ( 1A2B, 2A1B), (Z-1A 1C, 2A2C), (1A3C, 2A1C), (Z-1A1C, 2A 3C) and the simultaneous down-regulation of the pairs of antagonists (1A1B, 2A2B), (1A 2C, 2A1C), (E-1A1C, 2A3C), (1A3C, 2A 1C). The orthogonal dual adaptation undergone by the set of acylhydrazones amounts to a network switching process. © 2014 American Chemical Society.

Zhang Z.,Jilin University | Yao D.,Jilin University | Zhou T.,Jilin University | Zhang H.,Jilin University | Wang Y.,Jilin University
Chemical Communications | Year: 2011

Crystalline samples of 3(5)-(9-anthryl)pyrazole and its one derivative exhibit interesting piezochromic behaviors with the emission colors differently changing from blue to green and from green to blue, respectively, upon grinding. © 2011 The Royal Society of Chemistry.

Zhu S.,Jilin University | Song Y.,Jilin University | Zhao X.,Jilin University | Shao J.,Jilin University | And 2 more authors.
Nano Research | Year: 2015

At present, the actual mechanism of the photoluminescence (PL) of fluorescent carbon dots (CDs) is still an open debate among researchers. Because of the variety of CDs, it is highly important to summarize the PL mechanism for these kinds of carbon materials; doing so can guide the development of effective synthesis routes and novel applications. This review will focus on the PL mechanism of CDs. Three types of fluorescent CDs were involved: graphene quantum dots (GQDs), carbon nanodots (CNDs), and polymer dots (PDs). Four reasonable PL mechanisms have been confirmed: the quantum confinement effect or conjugated π-domains, which are determined by the carbon core; the surface state, which is determined by hybridization of the carbon backbone and the connected chemical groups; the molecule state, which is determined solely by the fluorescent molecules connected on the surface or interior of the CDs; and the crosslink-enhanced emission (CEE) effect. To give a thorough summary, the category and synthesis routes, as well as the chemical/physical properties for the CDs, are briefly introduced in advance. © 2014, Tsinghua University Press and Springer-Verlag Berlin Heidelberg.

Gao Z.,Jilin University | Cheng G.,Jilin University | Shen F.,Jilin University | Zhang S.,Jilin University | And 3 more authors.
Laser and Photonics Reviews | Year: 2014

Highly efficient deep blue fluorescent material (SiPIM) based on phenanthro[9, 10-d]imidazole (PPI) and triphenylsilane is designed and synthesized. SiPIM presents a narrow deep blue emission, high quantum yield, high thermal stability and good morphological stability. A non-doped vacuum-deposited device using SiPIM as active layer achieves an extremely high external quantum efficiency of 6.29% with true deep blue CIE coordinates of (0.163, 0.040). The solution-processed device is also tried due to the good solubility of SiPIM, which displays a maximum ηext of 2.40% and CIE coordinates of (0.157, 0.041). © 2013 by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Adekola K.A.,Jilin University
Agricultural Engineering International: CIGR Journal | Year: 2015

In this study, two-dimensional flow simulation in food extruder die for intermeshing co-rotating twin-screw extruder were performed by solving Navier-Stokes equation and continuity equation for non-Newtonian fluid using finite element computer package of ANSYS/FLOTRAN. The objective of the study is to determine the nature of flow, heat and pressure distribution in the die and to determine the effect of screw speed on process parameters such as temperature, pressure and flow rate in the die. Four different die geometries were used. The levels of temperature considered were 120°C, 140°C, 160°C and 180°C. The screw speeds (taken as inlet velocity for the die) were 120, 160, 200 and 240 rpm. The results are presented for the flow profile, pressure distribution, temperature distribution and flow rate. For all the velocities considered, temperature has no significant effect on the velocity vector. The concentration of the vectors increase as the cross-sectional area becomes smaller. The vectors are relatively linear and smooth in the transition section of the die and get concentrated towards the die exit. The flow rate increases with increase in inlet velocity. Extruder throughput has a significant effect on the flow rate as reflected in higher flow rate recorded for increased throughput. The pressure at the die exit is lower than the highest pressure obtained for all the experimental runs. As the dough gets to the die exit, the dough experienced pressure drop. A pressure drop of more than 0.8MPa between the entrance and exit of the die was obtained. Experimental results obtained for the die geometries statistically correlate with the simulation results. © 2015, Int. Comm. of Agricultural and Biosystems Engineering. All rights reserved.

Tan L.-L.,Jilin University | Yang Y.-W.,Jilin University
Journal of Inclusion Phenomena and Macrocyclic Chemistry | Year: 2015

As a rapidly developing class of synthetic macrocycles with intrinsic characteristics and properties, pillarenes (or pillararenes) have become more and more attractive on account of their unique features and potentials in fabricating functional materials. This feature article provides an overview of molecular recognition and selfassembly of pillarenes. The host-guest motifs, building strategies, topological architectures, stimuli-responsiveness, functionalities and various supramolecular assemblies including mechanically interlocked molecules containing rotaxanes, polyrotaxanes and catenanes, self-inclusion complexes, supramolecular dimers and polymers, micelles, vesicles, tubes and artificial transmembrane channels are comprehensively discussed. Prospects about future research directions and applications in this research area are predicted. © Springer Science+Business Media Dordrecht 2014.

Wang B.,Jilin University | Yin Z.-D.,Jilin University | Bi L.-H.,Jilin University | Wu L.-X.,Jilin University
Chemical Communications | Year: 2010

We selected a Eu3+-containing tungstogermanate [(CH 3)4N]2.5H7.5[Eu(GeW 11O39)(H2O)2]2·4. 5H2O (EuGeW) as a molecular dyad combining fluorescence and electroactivity components within the same framework and studied its electroswitchable fluorescence in solution and in the thin-film, which can be reversibly switched by electrochemical stimulation. © 2010 The Royal Society of Chemistry.

Guo J.,Jilin University | Liu X.-S.,Jilin University | Chu S.-I.,University of Kansas
Physical Review A - Atomic, Molecular, and Optical Physics | Year: 2013

The nonsequential double ionization (NSDI) of Mg atoms is investigated in both linearly and circularly polarized laser fields with different kinds of potentials. The numerical results indicate that the "knee" structure still exists in circularly polarized laser fields in the 800-nm case with different potentials, which can be well explained by the corresponding momentum and position distribution of electrons. Moreover, the ionized electron energy of Mg atoms at the end of the pulse also shows that the behavior of rescattering electrons is different between linearly and circularly polarized cases. Besides, we also look into the angular distribution at the end of the pulse with different kind of potentials to illustrate the difference in the double-ionization mechanism between the linearly and circularly polarized cases. © 2013 American Physical Society.

Yu A.-Y.,Jilin University
Canadian Journal of Chemistry | Year: 2013

In this work, the reaction mechanism and kinetics of Cl + CH 2BrCH2Br → products are theoretically investigated for the first time. The optimized geometries and frequencies of all of the stationary points and selected points along the minimum-energy path for the three hydrogen abstraction channels and two bromine abstraction channels are calculated at the BH&H-LYP level with the 6-311G** basis set and the energy profiles are further calculated at the CCSD(T) level of theory. The rate constants are evaluated using the conventional transition-state theory, the canonical variational transition-state theory, and the canonical variational transition-state theory with a small-curvature tunneling correction over the temperature range 200-1000 K. The results show that reaction channel 3 is the primary channel and the calculated rate constants are in good agreement with available experimental values. The three-parameter Arrhenius expression for the total rate constants over 200-1000 K is provided. © 2013 Published by NRC Research Press.

Zhu Z.,Jilin University | Zhou X.,Jilin University | Luo D.,Jilin University | Liu Q.,Jilin University
Optics Express | Year: 2013

In this paper, a novel pseudo-random diamond turning (PRDT) method is proposed for the fabrication of freeform optics with scattering homogenization by means of actively eliminating the inherent periodicity of the residual tool marks. The strategy for accurately determining the spiral toolpath with pseudo-random vibration modulation is deliberately explained. Spatial geometric calculation method is employed to determine the toolpath in consideration of cutting tool geometries, and an iteration algorithm is further introduced to enhance the computation efficiency. Moreover, a novel two degree of freedom fast tool servo (2-DOF FTS) system with decoupled motions is developed to implement the PRDT method. Taking advantage of a novel surface topography generation algorithm, theoretical surfaces generated by using the calculated toolpaths are obtained, the accuracy of the toolpath generation and the efficiency of the PRDT method for breaking up the inherent periodicity of tool marks are examined. A series of preliminary cutting experiments are carried out to verify the efficiency of the proposed PRDT method, the experimental results obtained are in good agreement with the results obtained by numerical simulation. In addition, the results of scattering experiments indicate that the proposed PRDT method will be a very promising technique to achieve the scattering homogenization of machined surfaces with complicated shapes. © 2013 Optical Society of America.

Song N.,Jilin University | Yang Y.-W.,Jilin University
Chemical Society Reviews | Year: 2015

Nanotechnology has attracted much attention because it possesses many advantages to engineer new organized nanomaterials and endow them with improved performance. In recent decades, mesoporous silica nanoparticles (MSNs) have been proven to be excellent solid supports owing to their superior properties. Molecular and supramolecular switches have also received a lot of interest in the past decade on account of their unique features. Materials derived from the combination of MSNs as solid supports and molecular/supramolecular switches as movable entities have emerged in the literature and are playing prominent roles in materials science nowadays. Thus, in this review, we chose to gather significant and typical examples of intelligent materials, which comprise MSNs surface-immobilized with molecular and supramolecular switches, and overview their wide applications in many fields such as controlled release of cargo molecules for disease therapy and cell imaging. Utilizing the switching ability of molecular and supramolecular switches, smart hybrid nanomaterials are endowed with intelligently controllable properties in response to a variety of external stimuli such as pH variation, enzyme, light irradiation, temperature, redox, magnetic field, competition, and ultrasound. In order to rationalize the presentation concisely, we will introduce molecular switches and supramolecular switches cooperated with MSNs based on their different features and the actuations they are responsive for. © The Royal Society of Chemistry 2015.

Tong J.,CAS Changchun Institute of Applied Chemistry | Wu Z.,CAS Changchun Institute of Applied Chemistry | Li Y.,Jilin University | Wu D.,Jilin University
Dalton Transactions | Year: 2013

A series of polynuclear superalkali cations YLi3+ (Y = O2, CO4, C2O4, and C 2O6) have been studied using ab initio method. The structural characters and stabilities of these systems are found to be related to the nature of the central cores. In the lowest-energy structure of the C 2O4Li3+ cations, the central group features a slight distortion. While in the global minima of O2Li 3+, CO4Li3+ and C 2O6Li3+ cations, the central cores are divided into various units including one peroxo group (O2). These YLi3+ (Y = O2, CO4, C 2O4, and C2O6) species exhibit very low vertical electron affinities of 3.01-3.85 eV (except one outlier in one of the O2Li3+ species which lie much higher in energy than the most stable structure) and hence should be classified as superalkali cations, and the corresponding neutral species can be regarded as superalkalies. Such polynuclear superalkalies are candidates to the superatoms and offered potential building blocks for the assembly of new materials in which strong electron donors are involved. © 2013 The Royal Society of Chemistry.

Li Y.,Jilin University | Li L.,Jilin University | Sun J.,Jilin University
Angewandte Chemie - International Edition | Year: 2010

Heal thyself! Self-healing superhydrophobic coatings are fabricated by preserving healing agents of reacted fluoroalkylsilane in layered polymeric coatings that are porous and rigidly flexible. When the top layer of fluoroalkyl chains decomposes or the coatings are scratched, the healing agents migrate to the surface to restore the superhydrophobicity of the coatings (see picture). © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Wu X.,Wuhan University | Wang X.,Jilin University | Zhang Y.,Wuhan University | Zhang Y.,Jilin University
ACS Applied Materials and Interfaces | Year: 2013

Nanoworm-like Li2FeSiO4-C composites are synthesized using triblock copolymer Pluronic P123 (poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide), EO20PO70EO20) as the structure directing agent (SDA) and under the effects of ethanol. As a polar nonaqueous cosolvent, ethanol has effects on the self-organization behavior of Pluronic P123 in water, which determines the final morphologies of the Li2FeSiO4-C composites synthesized. Li 2FeSiO4-C composite nanoparticles are obtained if no ethanol is added into the system during the synthesis process. When tested as lithium-ion battery cathodes, the Li2FeSiO4-C nanoworms show superior electrochemical performances. At the rate of 1 C (1 C = 166 mA g-1) the discharge capacity of the Li2FeSiO4-C nanoworms can reach 166 mAh g-1 in the voltage window of 1.5-4.8 V at room temperature. At the rates