Jiaxing College

Jiaxing, China

Jiaxing College

Jiaxing, China
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Han D.,Jiaxing College
Chinese Journal of Oncology | Year: 2012

Objective: To explore the cytotoxic responses of spleen T lymphocytes (CTL) in BALB/c mice induced by recombinant HSP110-HER2/neu ICD complex. Methods: Tumor-bearing mouse model was immunized by HSP110-HER2/neu ICD complex. The IFN-γ level secreted by activated spleen T lymphocytes was detected by enzyme linked immunospot assay (ELISPOT). The corresponding CTL activity was measured by granzyme release assay. Results: The BALB/c mouse model of human mammary tumor highly expressing HER2/neu was established. HSP110-HER2/neu ICD complex immunization led to a significantly higher level of INF-γ than that in HSP110-P789-797 immunized and HER2/neu ICD immunized mice. HSP110-HER2/neu ICD complex immunized animals also show significant CTL activity. The results of immunohistochemical staining showed that the number of blue spots in the PBS group was 4.57 ± 1.33, HSP110 group 6.83 ± 2.08, HER2/neu ICD group 16.17 ± 2.86, HSP110-P789-797 group 43.67 ± 4.78, and SP110-HER2/neu ICD group 76.51 ± 8.17. The number of IFN-γ-secreting spleen lymphocytes in the HSP110-HER2/neu ICD group was significantly higher than that in the HSP110-P789-797, group, and that of HSP110-P789-797 group was significantly higher than that of HER2/neu ICD group (P < 0.01). The target cell-killing rate of the PBS group was (8.15 ± 1.27)%, HSP110 group (9.51 ± 1.51)%, HER2/neu ICD group (14.03 ± 2.45)%, HSP110-P789-797 group (25.99 ± 3.04)% and HSP110-HER2/neu ICD group (38.15 ± 3.95) % (all P < 0.01). Conclusions: HSP110-HER2/neu ICD complex can promote the proliferation and maturation of T lymphocytes into CTLs, and might be used as anti-tumor vaccine to induce potent cytotoxic T lymophocyte immunoresponse against specific tumor cells.


The resistivity related to temperature and magnetic field is a crucial parameter for determining the physical properties of the perovskite-type manganese oxide. The first task of this work is to find out a suitable method to predict the resistivities of La0.67Ca0.33MnO3 and Pr0.7Sr0.3MnO3 in the process from insulator phase to the metal phase via the temperature and the magnetic field. Based on the nonlinear numerical fitting, an analytical expression showing the dependence of the resistivity on temperature both less than and higher than the metal-insulator transition Curie temperature (TC) at different magnetic fields, and the maximum resistivity (ρmax) corresponding to each Curie temperature is acquired. The second task of this work is to trace a mathematical relationship between the magnetic field and the maximum resistivity, and the Boltzmann function can be used successfully by numerical fitting. The lowest correlation coefficient and the largest average relative error between the actual and the calculated data are 0.998 and 4.35% in all considered cases respectively. © Chinese Physical Society.


Qian C.,Jiaxing College
Advanced Materials Research | Year: 2011

With the development of automotive industry, automotive air-conditioning filter became the essential equipment in people's daily life. On today's market, there is half of the filtration equipment made from non-woven materials because of its small resistance, good filtration efficiency, high yield and low cost advantages. In this paper, based on the comparison and analyses of the web structure, fiber distribution and finesse, permeability, thickness and filtration efficiency of the newly developed nonwoven composites and other imported materials, the results were got that the finer fibers, more porosity, thinner thickness and smaller holes together would make an ideal filtering product for using in the cleaner car. © (2011) Trans Tech Publications, Switzerland.


In order to probe the possibility of utilizing chromed leather wastes from the view of textile, firstly ultra-short leather fiber of 0.01∼0.5cm was extracted by special equipment. Then the fiber structure was characterized; the moisture absorbency was tested and compared with wool and silk protein fibers. On the above basis, ultra-short collagen fiber suede fabric was developed successfully. The results indicate that ultra-short collagen fibers exist in bundles, adhesion forces between fibers are larger those of single (bundle) fiber strength. Their moisture absorbency is similar to that of wool. The micro-suede fabric made is suitable for decorating materials. © (2011) Trans Tech Publications, Switzerland.


Qian C.,Jiaxing College
Advanced Materials Research | Year: 2012

The relations between properties and processing parameters of needle-punched composite geotextiles are tentatively discussed in the paper. In the meantime, a new kind of adhesive bonded composite geotextiles are developed in the laboratory. Then the hydrokenetic properties of the two composite geotextiles are analyzed and compared. The results were got that with the increment of needle-punching density, breaking strength, vertical permeate coefficient and O95 of needle-punched composite geotextiles are all increase, whereas peeling strength decreases. With the rise of needle-punching depth, the breaking strength decreases, but both peeling strength and O95 are increase. Meanwhile, with the rise of bonded area, adhesive bonded composite geotextiles have good permeate property. On the other hand, adhesive bonded composite geotextiles have similar peeling strength compared with needle-punched composite geotextiles, but manifested with better permeability.


Qian C.,Jiaxing College
Advanced Materials Research | Year: 2012

For making eco-friendly cellulose sponge, cellulose pulp dissolving properties were researched in this paper. NaOH and NaOH/Urea solutions were both used, various factors (temperature, concentration and time) on viscosity of the pulp were studied. At first, ten different kinds of cellulose pulps were dissolved at low temperature in a certain range of concentration of NaOH solvent and the pulp with best soluble property was chosen. On the above basis, effects of the temperature of alkaline solvent and concentration on the viscosity of the selected pulp was fatherly experimented and analyzed. The result was got that at concentration of 8% of NaOH solution and at temperature of -5°C, the cellulose pulp has the best solubility. In the meantime, the solution has the biggest viscosity. On the other hand, NaOH/Urea solvent was tested for cellulose solubility. After experiment, the tests showed that when NaOH/Urea blending ratio is 8:12, the selected pulp solves completely and the solution was clear. Thus NaOH/Urea solvent has better solubility than that of NaOH solution for solving the cellulose pulp.


Zhong M.-P.,Jiaxing College
Applied Mechanics and Materials | Year: 2012

A mathematical model of operation on air compressors is set up in order to improve the efficiency of air compressors. Parameter of Compressor is optimized by an Ant Colony Optimization (ACO) Particle approach. Volume and its weight of the new compressor are little, and its efficiency is high. An Ant Colony Optimization embed BLDCM module which optimizating the air compressor was put forward. Optimizated target of an Ant Colony Optimization is the efficiency of BLDCM. Optimizated variables are the diameter of low pressure cylinder, the diameter of high pressure cylinder, the journey of low pressure piston, the journey of high pressure piston and the rotate speed of BLDCM. Simulated result shows that the efficiency of BLDCM is more than that before optimizating. The test is done. The result shows that the specifc Power of air compressor is much less than before optimizating on 2.5Mpa. The result also shows that an Ant Colony Optimization which optimizating the air compressor is availability and practicality. © (2012) Trans Tech Publications, Switzerland.


Qian C.,Jiaxing College
Journal of the American Leather Chemists Association | Year: 2014

In this paper, the possibility of making use of wet-blue leather wastes on a large scale through a nonwoven method was investigated. Firstly, collagen fibers were extracted from the wastes and their structure was characterized. The water absorbency of collagen fibers was tested and compared with that of wool and silk fibers. Then, we successfully developed a composite of regenerated collagen fibers on a base layer of PA/PET and viscose fiber, and tested their physical properties. The results indicated that most of the extracted short collagen fibers existed in bundles, their fibers' length were in the range of 25-45 mm, and their finesse was in the range of 2-5μm. The extent of water absorption of collagen fibers was similar to that of wool fiber. The collagen fiber composite on the base layer of PA/PET had good tensile and tearing strength. Moreover, the composite had good moisture permeability with the viscose fibers as a support base layer.


Changshi L.,Jiaxing College
Journal of Chemical and Engineering Data | Year: 2011

Temperature- and magnetic field-dependent resistivity is a crucial parameter in determining the physical properties of manganites. The first objective of this work was to find out an applicable method of using temperature to predict the resistivity and control the transition of La 0.8Sr0.2MnO3 and La0.67Ca 0.33MnO3 from the insulator phase to the metal phase in the transition area. Predicated on nonlinear curve fitting, a typical numerical method is used to quantitatively analyze the temperature-dependent resistivity for temperatures both less than and higher than the metal-insulator transition temperature (Tp). The simulations agree very well with the observed spectra (resistivity versus temperature). The second objective of this work was to find out the mathematical relationships between the magnetic field and the maximum resistivity ρmax as well as the metal-insulator transition temperature, Tp. On the basis of the calculated results from the nonlinear curve fitting method, the magnetic field-dependent T p and ρmax are theoretically explained successfully via three functions. The minimum correlation coefficient between the actual and the calculated data is 0.994. The average relative errors between the measured and the modeled quantities do not exceed 5.86 % in all considered cases. To my knowledge, the effects of the magnetic field on the shift of both the maximum resistivity and the metal-insulator transition temperature of manganites are quantitatively discussed for the first time. © 2010 American Chemical Society.


Zhong M.-P.,Jiaxing College
Proceedings - 2012 IEEE Symposium on Electrical and Electronics Engineering, EEESYM 2012 | Year: 2012

The new portable compressor was designed and manufactured. Volume and its weight of The new portable compressor are little, and its efficiency is high. Three-dimensional model of the new portable compressor is Established. Forces principle of air compressor and load moment are analysised. The measure reciprocating inertial force of the new portable compressor is analysised and Controlled. Simulation Model of The new portable compressor is built up in Simulink of Matlab. Rotate speed of two compressor and current of two compressor are Simulated. The Current of opposed type is much more than that of contraposition type. The half of horizontal reciprocating inertial force is transferred to the perpendicularity, which can reduce the vibration horizontal vibration, so that reduce the vibration of the direct-drive air compressor. The test is done. The result shows that rotate speed fluctuate of dual- same movement pistons compressor is less. The efficiency of opposed type compressor is much higher than that of dual- same compressor. © 2012 IEEE.

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