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Yu X.,Jiashan No1 Peoples Hospital | Liang G.,Shanghai Hospital of Traditional Chinese Medicine | Wu M.,Shanghai JiaoTong University | Zheng J.,Jiashan No1 Peoples Hospital | And 7 more authors.
Chinese Journal of Andrology | Year: 2015

Objective To investigate the prevalence of benign prostatic hyperplasia (BPH) among old and middle-aged males in community inhabitants. Methods A cross-sectional randomized study of 2 000 men aged between 40 to 70 years was performed in Shanghai and Zhejiang community. The lower urinary tract symptoms (LUTS) was investigated by International Prostate Symptom Score (IPSS). The length, width, height of prostate zone were measured by transrectal ultrasonography (TRUS) in each volunteer for calculating the prostate volume (PV). The data were processed by one-way analysis of variance. Results Totally 1,982 cases meeting the study criteria were included in the investigation. The mean age was (57.85±8.33) years old. The mean IPSS and PV were (5.43±3.21) and (29.86±20.32)mL respectively. The prevalence of moderate and severe LUTS was 50.61%(1 003/1 982). The PV was over 20mL in 68.92%(1 366/1 982). The incidence rate of BPH was 29.97%. Of three groups with different ages, the BPH prevalence was 2.03%, 24.89% and 54.18% respectively. It showed a trend of increase with age (P<0.01). The prevalence of BPH was 36.58% in Shanghai community, while 23.42% in Zhejiang area. Conclusion The BPH prevalence was serious among old and middle-aged males in community inhabitants, especially in urban and should be given much more attention. © 2015, Shanghai Jiaotong University School of Medicine. All rights reserved.


Liang G.-Q.,Shanghai University of Traditional Chinese Medicine | Yu X.-H.,Jiashan No1 Peoples Hospital | Wu M.,Shanghai JiaoTong University | Shen Y.-Z.,Jiashan No1 Peoples Hospital | And 7 more authors.
Journal of Shanghai Jiaotong University (Medical Science) | Year: 2014

Objective: To study the relationship of erectile function (EF) and serum total testosterone (TT), free testosterone (FT), and bioavailable testosterone (Bio-T) of old and middle-aged males. Methods: The International Index of Erectile Function questionnaires was used to evaluate 236 people with normal EF, 369 patients with mild erectile dysfunction (ED), and 390 patients with moderate and severe ED. The serum total testosterone (TT) and sex hormone-binding globulin (SHBG) were measured by chemilum inescentenzyme immunoassay (CLIA) method, and free testosterone (FT) and bioavailable testosterone (Bio-T) levels were calculated. Results: The incidence of ED was 76.28% among old and middle-aged males and increased significantly with the age. The TT levels of ED patients were slightly lower than those of people with normal EF (P>0.05). While FT and Bio-T values were significantly lower than those of people with normal EF (P<0.01). The variations of TT among ED patients with different IIEF scores are not regular, while FT and Bio-T decreased significantly with decreasing of IIEF score. Pearson regression analysis revealed that TT was not related to IIEF score, while FT and Bio-T were significantly related to IIEF score (P<0.01). Conclusion: The incidence of ED among old and middle-aged males increases significantly with the age. The TT level is not significantly related to ED, but FT and Bio-T are significantly related to ED. The endocrine diagnostic value of FT and Bio-T is better than TT and can reflect the serum testosterone level of ED patients more accurately.

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